Cathepsins are upregulated by IFN-γ/STAT1 in human muscle culture: A possible active factor in dermatomyositis

Journal of Neuropathology and Experimental Neurology

Volumn 60, Issue 9, 2001, Pages 847-855

  Gallardo, Eduard ^a   De Andrés, Irene ^a   Illa, Isabel ^a,b  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

Cathepsins; Dermatomyositis; Fludarabine; IFN STAT1; Inflammatory myopathy

Indexed keywords

BETA ACTIN; CALPAIN; CATHEPSIN; CATHEPSIN B; CATHEPSIN L; DESMIN; FAS ANTIGEN; FLUDARABINE; GAMMA INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NERVE CELL ADHESION MOLECULE; PROTEIN BCL X; PROTEIN P21; STAT1 PROTEIN; STRUCTURAL PROTEIN; UTROPHIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE; CLINICAL ARTICLE; CONTROLLED STUDY; DERMATOMYOSITIS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MUSCLE ATROPHY; MUSCLE FIBER CULTURE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 0034837026     PISSN: 00223069     EISSN: None     Source Type: Journal    
DOI: 10.1093/jnen/60.9.847     Document Type: Article

References (41)

1. Polymyositis, dermatomyositis and inclusion-body myositis
2. The immunobiology of muscle
3. Dermatomyositis, polymyositis and inclusion body myositis: Current concepts
4. The polymyositis and dermatomyositis syndromes
5. New developments in the role of cytokines and chemokines in inflammatory myopathies
6. Immunofluorescent evidence for presence of interleukin-1 in normal and diseased human skeletal muscle
7. Cytokine expression profile in idiopathic inflammatory myopathies
8. Cytokine production in muscle tissue of patients with idiopathic inflammatory myopathies
9. Tumor necrosis factor-alpha expression in muscles of polymyositis and dermatomyositis
10. Immunolocalization of tumor necrosis factor-alpha and its receptors in inflammatory myopathies
11. Analysis of cytokine expression in muscle in inflammatory myopathies, Duchenne dystrophy, and non-weak controls
12. Activation of transcription by IFN-γgamma: Tyrosine phosphorylation of a 91-kD DNA binding protein
13. Signal transducer and activator of transcription 1 in human muscle: Implications in inflammatory myopathies
14. Jaks and Stats in signaling by the cytokine receptor superfamily
15. Cellular responses to interferon-gamma
16. Acute quadriplegic myopathy: Analysis of myosin isoforms and evidence for calpain-mediated proteolysis
17. Calpain and cathepsins in the skeletal muscle of inflammatory myopathies
18. Fludarabine-induced immunosuppression is associated with inhibition of STAT1 signaling
19. A new program for investigating adult human muscle grown aneurally in tissue culture
20. Regenerating and denervated human muscle fibers and satellite cells express neural cell adhesion molecule recognized by monoclonal antibodies to natural killer cells
21. Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells
22. Cleavage of structural proteins during the assembly of the head of the bacteriophage T4
23. Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: Procedure and some applications
24. Activation of a human T cell line: A two-stimulus requirement in the pretranslational events involved in the coordinate expression of interleukin 2 and gamma-interferon genes
25. Specific regulation of N-CAM/D2CAM cell adhesion molecule during skeletal muscle development
26. Helix-loop-helix proteins as regulators of muscle-specific transcription
27. Neural cell adhesion molecule in normal, denervated, and myopathic human muscle
28. Fas antigen expression on CD34+ human marrow cells is induced by interferon gamma and tumor necrosis factor alpha and potentiates cytokine-mediated hematopoietic suppression in vitro
29. Interferon-gamma-dependent stimulation of Fas antigen in SV40-transformed human keratinocytes: Modulation of the apoptotic process by protein kinase C
30. Signals through gp130 upregulate bcl-x gene expression via STAT1- binding cis-element in cardiac myocytes
31. Cell growth arrest and induction of cyclin-dependent kinase inhibitor p21 WAF1/CIP1 mediated by STAT1
32. Induction of HLA-DR expression on human myoblasts with interferon-gamma
33. Constitutive and cytokine-induced expression of human leukocyte antigens and cell adhesion molecules by human myotubes
34. Gamma-interferon causes a selective induction of the lysosomal proteases, cathepsins B and L, in macrophages
35. T-cell anti-apoptotic mechanisms in inflammatory myopathies
36. Cytotoxic mechanisms in inflammatory myopathies. Co-expression of Fas and protective Bcl-2 in muscle fibres and inflammatory cells
37. The inhibition of apoptosis in myositis and in normal muscle cells
38. MHC class I-mediated cytotoxicity does not induce apoptosis in muscle fibers nor in inflammatory T cells: Studies in patients with polymyositis, dermatomyositis, and inclusion body myositis
39. Major histocompatibility complex class I antigen expression, immunolocalization of interferon subtypes, and T cell-mediated cytotoxicity in myopathies
40. Constitutive and cytokine-induced production of interleukin-6 by human myoblasts
41. Interferon gamma gene expression in sensory neurons: Evidence for autocrine gene regulation