Impaired CD4 T cell memory response to streptococcus pneumoniae precedes CD4 T cell depletion in HIV-infected Malawian adults

PLoS ONE

Volumn 6, Issue 9, 2011, Pages

  Glennie, Sarah J ^a   Sepako, Enoch ^a   Mzinza, David ^a   Harawa, Visopo ^a   Miles, David J C ^a,b   Jambo, Kondwani C ^a,c   Gordon, Stephen B ^c   Williams, Neil A ^d   Heyderman, Robert S ^a,d  

^a UNIVERSITY OF MALAWI   (Malawi)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

^c LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^d UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CD40 LIGAND; GAMMA INTERFERON; INTERLEUKIN 17;

ADULT; ANTIGEN EXPRESSION; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOMODULATION; LYMPHOCYTE COUNT; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MALE; MEMORY T LYMPHOCYTE; STREPTOCOCCUS PNEUMONIAE; T CELL DEPLETION; T LYMPHOCYTE ACTIVATION; UPREGULATION; ADOLESCENT; ASYMPTOMATIC INFECTION; BIOSYNTHESIS; CASE CONTROL STUDY; CELL AGING; CELL PROLIFERATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MALAWI; METABOLISM; MICROBIOLOGY; MIDDLE AGED; PATHOGENICITY; PATHOLOGY; REGULATORY T LYMPHOCYTE; SPECIES DIFFERENCE;

STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ADULT; ASYMPTOMATIC INFECTIONS; CASE-CONTROL STUDIES; CD4-POSITIVE T-LYMPHOCYTES; CD40 LIGAND; CELL AGING; CELL PROLIFERATION; FEMALE; HIV INFECTIONS; HUMANS; INTERFERON-GAMMA; INTERLEUKIN-17; MALAWI; MALE; MIDDLE AGED; SPECIES SPECIFICITY; STREPTOCOCCUS PNEUMONIAE; T-LYMPHOCYTES, REGULATORY; UP-REGULATION; YOUNG ADULT;

EID: 80053219521     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025610     Document Type: Article

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