-
1
-
-
20444427991
-
The anticoagulant protein C pathway
-
Dahlbäck B, Villoutreix BO. The anticoagulant protein C pathway. FEBS Lett 2005; 579: 3310-6.
-
(2005)
FEBS Lett
, vol.579
, pp. 3310-3316
-
-
Dahlbäck, B.1
Villoutreix, B.O.2
-
2
-
-
0029790055
-
The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex
-
Stearns-Kurosawa DJ, Kurosawa S, Mollica JS, Ferrell GL, Esmon CT. The endothelial cell protein C receptor augments protein C activation by the thrombin-thrombomodulin complex. Proc Natl Acad Sci U S A 1996; 93: 10212-6.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 10212-10216
-
-
Stearns-Kurosawa, D.J.1
Kurosawa, S.2
Mollica, J.S.3
Ferrell, G.L.4
Esmon, C.T.5
-
3
-
-
67849104652
-
Genetics of venous thrombosis
-
Rosendaal FR, Reitsma PH. Genetics of venous thrombosis. J Thromb Haemost 2009; 7(Suppl. 1): 301-4.
-
(2009)
J Thromb Haemost
, vol.7
, Issue.SUPPL. 1
, pp. 301-304
-
-
Rosendaal, F.R.1
Reitsma, P.H.2
-
4
-
-
0034603799
-
Genetic determinants of hemostasis phenotypes in Spanish families
-
Souto JC, Almasy L, Borrell M, Gari M, Martinez E, Mateo J, Stone WH, Blangero J, Fontcuberta J. Genetic determinants of hemostasis phenotypes in Spanish families. Circulation 2000; 101: 1546-51.
-
(2000)
Circulation
, vol.101
, pp. 1546-1551
-
-
Souto, J.C.1
Almasy, L.2
Borrell, M.3
Gari, M.4
Martinez, E.5
Mateo, J.6
Stone, W.H.7
Blangero, J.8
Fontcuberta, J.9
-
5
-
-
3042853035
-
Protein C levels are regulated by a quantitative trait locus on chromosome 16: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project
-
Buil A, Soria JM, Souto JC, Almasy L, Lathrop M, Blangero J, Fontcuberta J. Protein C levels are regulated by a quantitative trait locus on chromosome 16: results from the Genetic Analysis of Idiopathic Thrombophilia (GAIT) Project. Arterioscler Thromb Vasc Biol 2004; 24: 1321-5.
-
(2004)
Arterioscler Thromb Vasc Biol
, vol.24
, pp. 1321-1325
-
-
Buil, A.1
Soria, J.M.2
Souto, J.C.3
Almasy, L.4
Lathrop, M.5
Blangero, J.6
Fontcuberta, J.7
-
6
-
-
0028968010
-
Genotypic variation in the promoter region of the protein C gene is associated with plasma protein C levels and thrombotic risk
-
Spek CA, Koster T, Rosendaal FR, Bertina RM, Reitsma PH. Genotypic variation in the promoter region of the protein C gene is associated with plasma protein C levels and thrombotic risk. Arterioscler Thromb Vasc Biol 1995; 15: 214-8.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 214-218
-
-
Spek, C.A.1
Koster, T.2
Rosendaal, F.R.3
Bertina, R.M.4
Reitsma, P.H.5
-
7
-
-
0032984668
-
Complex association of protein C gene promoter polymorphism with circulating protein C levels and thrombotic risk
-
Aiach M, Nicaud V, Alhenc-Gelas M, Gandrille S, Arnaud E, Amiral J, Guize L, Fiessinger JN, Emmerich J. Complex association of protein C gene promoter polymorphism with circulating protein C levels and thrombotic risk. Arterioscler Thromb Vasc Biol 1999; 19: 1573-6.
-
(1999)
Arterioscler Thromb Vasc Biol
, vol.19
, pp. 1573-1576
-
-
Aiach, M.1
Nicaud, V.2
Alhenc-Gelas, M.3
Gandrille, S.4
Arnaud, E.5
Amiral, J.6
Guize, L.7
Fiessinger, J.N.8
Emmerich, J.9
-
8
-
-
52449099245
-
PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study
-
Reiner AP, Carty CL, Jenny NS, Nievergelt C, Cushman M, Stearns-Kurosawa DJ, Kurosawa S, Kuller LH, Lange LA. PROC, PROCR and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study. J Thromb Haemost 2008; 6: 1625-32.
-
(2008)
J Thromb Haemost
, vol.6
, pp. 1625-1632
-
-
Reiner, A.P.1
Carty, C.L.2
Jenny, N.S.3
Nievergelt, C.4
Cushman, M.5
Stearns-Kurosawa, D.J.6
Kurosawa, S.7
Kuller, L.H.8
Lange, L.A.9
-
9
-
-
78649735165
-
Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study
-
Tang W, Basu S, Kong X, Pankow JS, Aleksic N, Tan A, Cushman M, Boerwinkle E, Folsom AR. Genome-wide association study identifies novel loci for plasma levels of protein C: the ARIC study. Blood 2010; 116: 5032-6.
-
(2010)
Blood
, vol.116
, pp. 5032-5036
-
-
Tang, W.1
Basu, S.2
Kong, X.3
Pankow, J.S.4
Aleksic, N.5
Tan, A.6
Cushman, M.7
Boerwinkle, E.8
Folsom, A.R.9
-
10
-
-
62549112168
-
Assessment of coagulation and fibrinolysis in families with unexplained thrombophilia
-
Wichers IM, Tanck MW, Meijers JC, Lisman T, Reitsma PH, Rosendaal FR, Büller HR, Middeldorp S. Assessment of coagulation and fibrinolysis in families with unexplained thrombophilia. Thromb Haemost 2009; 101: 465-70.
-
(2009)
Thromb Haemost
, vol.101
, pp. 465-470
-
-
Wichers, I.M.1
Tanck, M.W.2
Meijers, J.C.3
Lisman, T.4
Reitsma, P.H.5
Rosendaal, F.R.6
Büller, H.R.7
Middeldorp, S.8
-
11
-
-
78651068305
-
Quantitative trait locus for protein C in a family with thrombophilia
-
Tanck MW, Wichers IM, Meijers JC, Büller HR, Reitsma PH, Middeldorp S. Quantitative trait locus for protein C in a family with thrombophilia. Thromb Haemost 2011; 105: 199-201.
-
(2011)
Thromb Haemost
, vol.105
, pp. 199-201
-
-
Tanck, M.W.1
Wichers, I.M.2
Meijers, J.C.3
Büller, H.R.4
Reitsma, P.H.5
Middeldorp, S.6
-
12
-
-
0028805704
-
Two mutations in the promoter region of the human protein C gene both cause type I protein C deficiency by disruption of two HNF-3 binding sites
-
Spek CA, Greengard JS, Griffin JH, Bertina RM, Reitsma PH. Two mutations in the promoter region of the human protein C gene both cause type I protein C deficiency by disruption of two HNF-3 binding sites. J Biol Chem 1995; 270: 24216-21.
-
(1995)
J Biol Chem
, vol.270
, pp. 24216-24221
-
-
Spek, C.A.1
Greengard, J.S.2
Griffin, J.H.3
Bertina, R.M.4
Reitsma, P.H.5
-
14
-
-
0034050886
-
Mechanisms by which soluble endothelial cell protein C receptor modulates protein C and activated protein C function
-
Liaw PC, Neuenschwander PF, Smirnov MD, Esmon CT. Mechanisms by which soluble endothelial cell protein C receptor modulates protein C and activated protein C function. J Biol Chem 2000; 275: 5447-52.
-
(2000)
J Biol Chem
, vol.275
, pp. 5447-5452
-
-
Liaw, P.C.1
Neuenschwander, P.F.2
Smirnov, M.D.3
Esmon, C.T.4
-
15
-
-
13244253704
-
Haplotypes of the EPCR gene, plasma sEPCR levels and the risk of deep venous thrombosis
-
Uitte de Willige S, van Marion V, Rosendaal FR, Vos HL, de Visser MCH, Bertina RM. Haplotypes of the EPCR gene, plasma sEPCR levels and the risk of deep venous thrombosis. J Thromb Haemost 2004; 2: 1305-10.
-
(2004)
J Thromb Haemost
, vol.2
, pp. 1305-1310
-
-
Uitte de Willige, S.1
van Marion, V.2
Rosendaal, F.R.3
Vos, H.L.4
de Visser, M.C.H.5
Bertina, R.M.6
-
16
-
-
33644859098
-
The Ser219-->Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype
-
Qu D, Wang Y, Song Y, Esmon NL, Esmon CT. The Ser219-->Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype. J Thromb Haemost 2006; 4: 229-35.
-
(2006)
J Thromb Haemost
, vol.4
, pp. 229-235
-
-
Qu, D.1
Wang, Y.2
Song, Y.3
Esmon, N.L.4
Esmon, C.T.5
-
17
-
-
43549096946
-
Alternative mRNA is favored by the A3 haplotype of the EPCR gene PROCR and generates a novel soluble form of EPCR in plasma
-
Saposnik B, Lesteven E, Lokajczyk A, Esmon CT, Aiach M, Gandrille S. Alternative mRNA is favored by the A3 haplotype of the EPCR gene PROCR and generates a novel soluble form of EPCR in plasma. Blood 2008; 111: 3442-51.
-
(2008)
Blood
, vol.111
, pp. 3442-3451
-
-
Saposnik, B.1
Lesteven, E.2
Lokajczyk, A.3
Esmon, C.T.4
Aiach, M.5
Gandrille, S.6
-
18
-
-
0029033740
-
Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study)
-
Koster T, Rosendaal FR, Briët E, van der Meer FJ, Colly LP, Trienekens PH, Poort SR, Reitsma PH, Vandenbroucke JP. Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study). Blood 1995; 85: 2756-61.
-
(1995)
Blood
, vol.85
, pp. 2756-2761
-
-
Koster, T.1
Rosendaal, F.R.2
Briët, E.3
van der Meer, F.J.4
Colly, L.P.5
Trienekens, P.H.6
Poort, S.R.7
Reitsma, P.H.8
Vandenbroucke, J.P.9
-
19
-
-
0028877463
-
Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results
-
Lander E, Kruglyak L. Genetic dissection of complex traits: guidelines for interpreting and reporting linkage results. Nat Genet 1995; 11: 241-7.
-
(1995)
Nat Genet
, vol.11
, pp. 241-247
-
-
Lander, E.1
Kruglyak, L.2
-
20
-
-
3042641333
-
2LD, GENECOUNTING and HAP: Computer programs for linkage disequilibrium analysis
-
Zhao JH. 2LD, GENECOUNTING and HAP: Computer programs for linkage disequilibrium analysis. Bioinformatics 2004; 20: 1325-6.
-
(2004)
Bioinformatics
, vol.20
, pp. 1325-1326
-
-
Zhao, J.H.1
-
21
-
-
0842307339
-
A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis
-
Saposnik B, Reny JL, Gaussem P, Emmerich J, Aiach M, Gandrille S. A haplotype of the EPCR gene is associated with increased plasma levels of sEPCR and is a candidate risk factor for thrombosis. Blood 2004; 103: 1311-8.
-
(2004)
Blood
, vol.103
, pp. 1311-1318
-
-
Saposnik, B.1
Reny, J.L.2
Gaussem, P.3
Emmerich, J.4
Aiach, M.5
Gandrille, S.6
-
22
-
-
73949130775
-
FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men
-
Ireland HA, Cooper JA, Drenos F, Acharya J, Mitchell JP, Bauer KA, Morrissey JH, Esnouf MP, Humphries SE. FVII, FVIIa, and downstream markers of extrinsic pathway activation differ by EPCR Ser219Gly variant in healthy men. Arterioscler Thromb Vasc Biol 2009; 29: 1968-74.
-
(2009)
Arterioscler Thromb Vasc Biol
, vol.29
, pp. 1968-1974
-
-
Ireland, H.A.1
Cooper, J.A.2
Drenos, F.3
Acharya, J.4
Mitchell, J.P.5
Bauer, K.A.6
Morrissey, J.H.7
Esnouf, M.P.8
Humphries, S.E.9
-
23
-
-
77950217693
-
Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: the CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium
-
Smith NL, Chen MH, Dehghan A, Strachan DP, Basu S, Soranzo N, Hayward C, Rudan I, Sabater-Lleal M, Bis JC, de Maat MP, Rumley A, Kong X, Yang Q, Williams FM, Vitart V, Campbell H, Malarstig A, Wiggins KL, van Duijn CM et al. Novel associations of multiple genetic loci with plasma levels of factor VII, factor VIII, and von Willebrand factor: the CHARGE (Cohorts for Heart and Aging Research in Genome Epidemiology) Consortium. Circulation 2010; 121: 1382-92.
-
(2010)
Circulation
, vol.121
, pp. 1382-1392
-
-
Smith, N.L.1
Chen, M.H.2
Dehghan, A.3
Strachan, D.P.4
Basu, S.5
Soranzo, N.6
Hayward, C.7
Rudan, I.8
Sabater-Lleal, M.9
Bis, J.C.10
de Maat, M.P.11
Rumley, A.12
Kong, X.13
Yang, Q.14
Williams, F.M.15
Vitart, V.16
Campbell, H.17
Malarstig, A.18
Wiggins, K.L.19
van Duijn, C.M.20
more..
-
24
-
-
44949100143
-
Haplotypes of the EPCR gene, prothrombin levels, and the risk of venous thrombosis in carriers of the prothrombin G20210A mutation
-
Navarro S, Medina P, Mira Y, Estellés A, Villa P, Ferrando F, Vayá A, Bertina RM, España F. Haplotypes of the EPCR gene, prothrombin levels, and the risk of venous thrombosis in carriers of the prothrombin G20210A mutation. Haematologica 2008; 93: 885-91.
-
(2008)
Haematologica
, vol.93
, pp. 885-891
-
-
Navarro, S.1
Medina, P.2
Mira, Y.3
Estellés, A.4
Villa, P.5
Ferrando, F.6
Vayá, A.7
Bertina, R.M.8
España, F.9
-
25
-
-
77952739912
-
Paternal endothelial protein C receptor 219Gly variant as a mild and limited risk factor for deep vein thrombosis during pregnancy
-
Galanaud JP, Cochery-Nouvellon E, Alonso S, Chauleur C, Mercier E, Lissalde-Lavigne G, Fabbro-Peray P, Reny JL, Mares P, Dauzat M, Quere I, Gris JC. Paternal endothelial protein C receptor 219Gly variant as a mild and limited risk factor for deep vein thrombosis during pregnancy. J Thromb Haemost 2010; 8: 707-13.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 707-713
-
-
Galanaud, J.P.1
Cochery-Nouvellon, E.2
Alonso, S.3
Chauleur, C.4
Mercier, E.5
Lissalde-Lavigne, G.6
Fabbro-Peray, P.7
Reny, J.L.8
Mares, P.9
Dauzat, M.10
Quere, I.11
Gris, J.C.12
-
26
-
-
2442433385
-
Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk
-
Medina P, Navarro S, Estellés A, Vayá A, Woodhams B, Mira Y, Villa P, Migaud-Fressart M, Ferrando F, Aznar J, Bertina RM, España F. Contribution of polymorphisms in the endothelial protein C receptor gene to soluble endothelial protein C receptor and circulating activated protein C levels, and thrombotic risk. Thromb Haemost 2004; 91: 905-11.
-
(2004)
Thromb Haemost
, vol.91
, pp. 905-911
-
-
Medina, P.1
Navarro, S.2
Estellés, A.3
Vayá, A.4
Woodhams, B.5
Mira, Y.6
Villa, P.7
Migaud-Fressart, M.8
Ferrando, F.9
Aznar, J.10
Bertina, R.M.11
España, F.12
-
27
-
-
63149130223
-
Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study
-
Yamagishi K, Cushman M, Heckbert SR, Tsai MY, Folsom AR. Lack of association of soluble endothelial protein C receptor and PROCR 6936A/G polymorphism with the risk of venous thromboembolism in a prospective study. Br J Haematol 2009; 145: 221-6.
-
(2009)
Br J Haematol
, vol.145
, pp. 221-226
-
-
Yamagishi, K.1
Cushman, M.2
Heckbert, S.R.3
Tsai, M.Y.4
Folsom, A.R.5
-
28
-
-
27644527760
-
EPCR Ser219Gly: elevated sEPCR, prothrombin F1+2, risk for coronary heart disease, and increased sEPCR shedding in vitro
-
Ireland H, Konstantoulas CJ, Cooper JA, Hawe E, Humphries SE, Mather H, Goodall AH, Hogwood J, Juhan-Vague I, Yudkin JS, di Minno G, Margaglione M, Hamsten A, Miller GJ, Bauer KA, Kim YT, Stearns-Kurosawa DJ, Kurosawa S. EPCR Ser219Gly: elevated sEPCR, prothrombin F1+2, risk for coronary heart disease, and increased sEPCR shedding in vitro. Atherosclerosis 2005; 183: 283-92.
-
(2005)
Atherosclerosis
, vol.183
, pp. 283-292
-
-
Ireland, H.1
Konstantoulas, C.J.2
Cooper, J.A.3
Hawe, E.4
Humphries, S.E.5
Mather, H.6
Goodall, A.H.7
Hogwood, J.8
Juhan-Vague, I.9
Yudkin, J.S.10
di Minno, G.11
Margaglione, M.12
Hamsten, A.13
Miller, G.J.14
Bauer, K.A.15
Kim, Y.T.16
Stearns-Kurosawa, D.J.17
Kurosawa, S.18
-
29
-
-
50849093562
-
Endothelial protein C receptor polymorphisms and risk of myocardial infarction
-
Medina P, Navarro S, Corral J, Zorio E, Roldán V, Estellés A, Santamaría A, Marín F, Rueda J, Bertina RM, España F. Endothelial protein C receptor polymorphisms and risk of myocardial infarction. Haematologica 2008; 93: 1358-63.
-
(2008)
Haematologica
, vol.93
, pp. 1358-1363
-
-
Medina, P.1
Navarro, S.2
Corral, J.3
Zorio, E.4
Roldán, V.5
Estellés, A.6
Santamaría, A.7
Marín, F.8
Rueda, J.9
Bertina, R.M.10
España, F.11
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