메뉴 건너뛰기




Volumn 1232, Issue 1, 2011, Pages 18-35

Barrett's esophagus: Genetic and cell changes

(17)  Souza, Rhonda F a   Freschi, Giancarlo b   Taddei, Antonio b   Ringressi, Maria Novella b   Bechi, Paolo b   Castiglione, Francesca c   Degl'Innocenti, Duccio Rossi c   Triadafilopoulos, George d   Wang, Jean S e   Chang, Andrew C f   Barr, Hugh g   Bajpai, Manisha h   Das, Kiron M h   Schneider, Paul M i   Krishnadath, Kausilia K j   Malhotra, Usha k   Lynch, John P l  


Author keywords

Adenocarcinoma; BAR T cells; Barrett's esophagus; Bile; BMP 4; CDKN2A; CDX 1gene; CDX 2 gene; Hedgehog pathway; Hox genes; IGF 1R genotype; Intestinal metaplasia; MAb Das 1; Mitogen activated protein kinase; NF B; P16; P53; TP53; Villin

Indexed keywords

BILE ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NOTCH RECEPTOR; PROTEIN P16; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR RUVB1; TRANSCRIPTION FACTOR RUVB2; TUMOR MARKER; UNCLASSIFIED DRUG; WNT PROTEIN;

EID: 80053207315     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2011.06043.x     Document Type: Article
Times cited : (5)

References (63)
  • 1
    • 28844461009 scopus 로고    scopus 로고
    • Prevalence of Barrett's esophagus in the general population: an endoscopic study
    • Ronkainen, J., P. Aro, T. Storskrubb, et al 2005. Prevalence of Barrett's esophagus in the general population: an endoscopic study. Gastroenterology 129: 1825-1831.
    • (2005) Gastroenterology , vol.129 , pp. 1825-1831
    • Ronkainen, J.1    Aro, P.2    Storskrubb, T.3
  • 2
    • 33749366481 scopus 로고    scopus 로고
    • Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastresophageal junction Cancer Epidemiol
    • Chak, A., H. Ochs-Balcom, G. Falk, et al 2006. Familiality in Barrett's esophagus, adenocarcinoma of the esophagus, and adenocarcinoma of the gastresophageal junction Cancer Epidemiol. Biomarkers Prev. 15: 1668-1673.
    • (2006) Biomarkers Prev. , vol.15 , pp. 1668-1673
    • Chak, A.1    Ochs-Balcom, H.2    Falk, G.3
  • 4
    • 47249089615 scopus 로고    scopus 로고
    • A pro-inflammatory genotype predisposes to Barrett's esophagus
    • Moons, L.M., J.G. Kusters, J.H. Van Delft, et al 2008. A pro-inflammatory genotype predisposes to Barrett's esophagus. Carcinogenesis 29: 926-931.
    • (2008) Carcinogenesis , vol.29 , pp. 926-931
    • Moons, L.M.1    Kusters, J.G.2    Van Delft, J.H.3
  • 5
    • 67649872357 scopus 로고    scopus 로고
    • A polymorphic variant of the insulin-like growth factor type I receptor gene modifies risk of obesity for esophageal adenocarcinoma
    • Macdonald, K., G.A. Porter, D.L. Guernsey, et al 2009. A polymorphic variant of the insulin-like growth factor type I receptor gene modifies risk of obesity for esophageal adenocarcinoma. Cancer Epidemiol. 33: 37-40.
    • (2009) Cancer Epidemiol. , vol.33 , pp. 37-40
    • Macdonald, K.1    Porter, G.A.2    Guernsey, D.L.3
  • 7
    • 33845380456 scopus 로고    scopus 로고
    • Molecular basis of Barrett's esophagus and esophageal adenocarcinoma
    • Fitzgerald, R.C. 2006. Molecular basis of Barrett's esophagus and esophageal adenocarcinoma. Gut. 55: 1810-1820.
    • (2006) Gut. , vol.55 , pp. 1810-1820
    • Fitzgerald, R.C.1
  • 8
    • 66349110898 scopus 로고    scopus 로고
    • Roles of caudal-related homeobox gene Cdx1 in esophageal epithelial cells in Barrett's epithelium development
    • Kazumori, H., S. Ishihara & Y. Kinoshita 2009. Roles of caudal-related homeobox gene Cdx1 in esophageal epithelial cells in Barrett's epithelium development. Gut. 58: 620-628.
    • (2009) Gut. , vol.58 , pp. 620-628
    • Kazumori, H.1    Ishihara, S.2    Kinoshita, Y.3
  • 9
    • 77951256261 scopus 로고    scopus 로고
    • The molecular pathogenesis of Barrett's esophagus: common signaling pathways in embryogenesis metaplasia and neoplasia
    • Peters, J.H. & N. Avisar 2010. The molecular pathogenesis of Barrett's esophagus: common signaling pathways in embryogenesis metaplasia and neoplasia. J. Gastroint. Surg. 14(Suppl 1): S81-S87.
    • (2010) J. Gastroint. Surg. , vol.14 , Issue.SUPPL. 1
    • Peters, J.H.1    Avisar, N.2
  • 10
    • 70349952360 scopus 로고    scopus 로고
    • Regulation of CDX2 expression in esophageal adenocarcinoma
    • Vaninetti, N., L. Williams, L. Geldenhuys, et al 2009.Regulation of CDX2 expression in esophageal adenocarcinoma. Mol. Carcinog. 48: 965-974.
    • (2009) Mol. Carcinog. , vol.48 , pp. 965-974
    • Vaninetti, N.1    Williams, L.2    Geldenhuys, L.3
  • 11
    • 0036161377 scopus 로고    scopus 로고
    • Acid exposure activates the mitogen-activated protein kinase pathways in Barrett's esophagus
    • Souza, R.F., K. Shewmake, L.S. Terada & S.J. Spechler 2002. Acid exposure activates the mitogen-activated protein kinase pathways in Barrett's esophagus. Gastroenterology 122: 299-307.
    • (2002) Gastroenterology , vol.122 , pp. 299-307
    • Souza, R.F.1    Shewmake, K.2    Terada, L.S.3    Spechler, S.J.4
  • 12
    • 0029907124 scopus 로고    scopus 로고
    • Dynamic effects of acid on Barrett's esophagus. Anex vivoproliferation and differentiation model
    • Fitzgerald, R.C., M.B. Omary, G. Triadafilopoulos 1996. Dynamic effects of acid on Barrett's esophagus. Anex vivoproliferation and differentiation model. J. Clin. Invest. 98: 2120-2128.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2120-2128
    • Fitzgerald, R.C.1    Omary, M.B.2    Triadafilopoulos, G.3
  • 13
    • 76649134465 scopus 로고    scopus 로고
    • Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers
    • Saadi, A., N.B. Shannon, P. Lao-Sirieix, et al. 2010. Stromal genes discriminate preinvasive from invasive disease, predict outcome, and highlight inflammatory pathways in digestive cancers. Proc. Natl. Acad. Sci. U. S. A. 107: 2177-2182.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 2177-2182
    • Saadi, A.1    Shannon, N.B.2    Lao-Sirieix, P.3
  • 14
    • 65949107556 scopus 로고    scopus 로고
    • Endoscopic evaluation of esophago-gastro-jejunostomy in rat model of Barrett's esophagus
    • Lu, S., A.W. Lowe, G. Triadafilopoulos, et al. 2009. Endoscopic evaluation of esophago-gastro-jejunostomy in rat model of Barrett's esophagus. Dis. Esophagus. 22: 323-330.
    • (2009) Dis. Esophagus. , vol.22 , pp. 323-330
    • Lu, S.1    Lowe, A.W.2    Triadafilopoulos, G.3
  • 15
    • 77955856948 scopus 로고    scopus 로고
    • Polyploidy, aneuploidy and the evolution of cancer
    • Merlo, L.M., L.S. Wang, J.W. Pepper, et al. 2010. Polyploidy, aneuploidy and the evolution of cancer. Adv. Exp. Med. Biol. 676: 1-13.
    • (2010) Adv. Exp. Med. Biol. , vol.676 , pp. 1-13
    • Merlo, L.M.1    Wang, L.S.2    Pepper, J.W.3
  • 16
    • 48249128273 scopus 로고    scopus 로고
    • Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's esophagus
    • Leedham, S.J., S.L. Preston, S.A. Mcdonald, et al. 2008. Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's esophagus. Gut. 57: 1041-1048.
    • (2008) Gut. , vol.57 , pp. 1041-1048
    • Leedham, S.J.1    Preston, S.L.2    Mcdonald, S.A.3
  • 17
    • 77649247178 scopus 로고    scopus 로고
    • Verification and unmasking of widely used human esophageal adenocarcinoma cell lines
    • Boonstra, J.J., R. Van Marion, D.G. Beer, et al 2010. Verification and unmasking of widely used human esophageal adenocarcinoma cell lines. J. Natl. Cancer Inst. 102: 271-274.
    • (2010) J. Natl. Cancer Inst. , vol.102 , pp. 271-274
    • Boonstra, J.J.1    Van Marion, R.2    Beer, D.G.3
  • 18
    • 34249668293 scopus 로고    scopus 로고
    • Characterization of telomerase- immortalized, non-neoplastic, human Barrett's cell line (BAR-T)
    • Jaiswal, K.R., C.P. Morales, L.A. Feagins, et al 2007. Characterization of telomerase- immortalized, non-neoplastic, human Barrett's cell line (BAR-T). Dis. Esophagus 20: 256-264.
    • (2007) Dis. Esophagus , vol.20 , pp. 256-264
    • Jaiswal, K.R.1    Morales, C.P.2    Feagins, L.A.3
  • 19
    • 0042169024 scopus 로고    scopus 로고
    • Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model
    • Palanca-Wessels, M.C., A. Klingelhutz, B.J. Reid, et al 2003. Extended lifespan of Barrett's esophagus epithelium transduced with the human telomerase catalytic subunit: a useful in vitro model. Carcinogenesis 24: 1183-1190.
    • (2003) Carcinogenesis , vol.24 , pp. 1183-1190
    • Palanca-Wessels, M.C.1    Klingelhutz, A.2    Reid, B.J.3
  • 20
    • 33645396945 scopus 로고    scopus 로고
    • Genetic clonal diversity predicts progression to esophageal adenocarcinoma
    • Maley, C.C., P.C. Galipeau, J.C. Finley, et al 2006. Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nat. Genet. 38: 468-473.
    • (2006) Nat. Genet. , vol.38 , pp. 468-473
    • Maley, C.C.1    Galipeau, P.C.2    Finley, J.C.3
  • 21
    • 35948975117 scopus 로고    scopus 로고
    • The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation
    • Okawa, T, C.Z. Michaylira, J. Kalabis, et al 2007. The functional interplay between EGFR overexpression, hTERT activation, and p53 mutation in esophageal epithelial cells with activation of stromal fibroblasts induces tumor development, invasion, and differentiation. Genes. Dev. 21: 2788-2803.
    • (2007) Genes. Dev. , vol.21 , pp. 2788-2803
    • Okawa, T.1    Michaylira, C.Z.2    Kalabis, J.3
  • 22
    • 78649248733 scopus 로고    scopus 로고
    • A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma
    • Merlo, L.M., N.A. Shah, X. Li, et al. 2010. A comprehensive survey of clonal diversity measures in Barrett's esophagus as biomarkers of progression to esophageal adenocarcinoma. Cancer Prev. Res. 3: 1388-1397.
    • (2010) Cancer Prev. Res. , vol.3 , pp. 1388-1397
    • Merlo, L.M.1    Shah, N.A.2    Li, X.3
  • 23
    • 78649251520 scopus 로고    scopus 로고
    • The origins and implications of intratumor heterogeneity
    • Michor, F. & K. Polyak 2010. The origins and implications of intratumor heterogeneity. Cancer Prev. Res. 3: 1361-1364.
    • (2010) Cancer Prev. Res. , vol.3 , pp. 1361-1364
    • Michor, F.1    Polyak, K.2
  • 24
    • 77953258292 scopus 로고    scopus 로고
    • Cellular origin of Barrett's metaplasia and esophageal stem cells
    • Barbera, M. & R.C. Fitzgerald 2010. Cellular origin of Barrett's metaplasia and esophageal stem cells. Biochem. Soc. Trans. 38: 370-373.
    • (2010) Biochem. Soc. Trans. , vol.38 , pp. 370-373
    • Barbera, M.1    Fitzgerald, R.C.2
  • 25
    • 0017167185 scopus 로고
    • The clonal evolution of tumor cell populations
    • Nowell, P.C. 1976. The clonal evolution of tumor cell populations. Science 194: 238.
    • (1976) Science , vol.194 , pp. 238
    • Nowell, P.C.1
  • 26
    • 33645396945 scopus 로고    scopus 로고
    • Genetic clonal diversity predicts progression to esophageal adenocarcinoma
    • Maley, C.C., P.C. Galipeau, J.C. Finley, et al 2006. Genetic clonal diversity predicts progression to esophageal adenocarcinoma. Nat. Genet. 38: 468-473.
    • (2006) Nat. Genet. , vol.38 , pp. 468-473
    • Maley, C.C.1    Galipeau, P.C.2    Finley, J.C.3
  • 27
    • 48249128273 scopus 로고    scopus 로고
    • Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's esophagus
    • Leedham, S.J., S.L. Preston, S.A.C. Mcdonald, et al 2008. Individual crypt genetic heterogeneity and the origin of metaplastic glandular epithelium in human Barrett's esophagus. Gut 57: 1041-1048.
    • (2008) Gut , vol.57 , pp. 1041-1048
    • Leedham, S.J.1    Preston, S.L.2    Mcdonald, S.A.C.3
  • 28
    • 0030436380 scopus 로고    scopus 로고
    • Migration of the ductular elements of Gut-associated glands gives clues to the histogenesis of structures associated with responses to acid hypersecretory state: The origins of "gastric metaplasia in the duodenum of specialised mucosa of Barrett's esophagus and pseudopyloric metaplasia
    • Wright, N.A. Migration of the ductular elements of Gut-associated glands gives clues to the histogenesis of structures associated with responses to acid hypersecretory state: The origins of "gastric metaplasia in the duodenum of specialised mucosa of Barrett's esophagus and pseudopyloric metaplasia. Yale J. Biol. Med. 69: 147-153.
    • Yale J. Biol. Med. , vol.69 , pp. 147-153
    • Wright, N.A.1
  • 29
    • 48249134659 scopus 로고    scopus 로고
    • Dissecting out the genetic origins of Barrett's esophagus
    • Fitzgerald, R.C. 2008. Dissecting out the genetic origins of Barrett's esophagus. Gut 57: 1033-1034.
    • (2008) Gut , vol.57 , pp. 1033-1034
    • Fitzgerald, R.C.1
  • 30
    • 5644255657 scopus 로고    scopus 로고
    • The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma
    • Maley, C.C., P.C. Galipeau, X. Li, et al. 2004. The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma. Cancer Res. 64: 7629-7633.
    • (2004) Cancer Res. , vol.64 , pp. 7629-7633
    • Maley, C.C.1    Galipeau, P.C.2    Li, X.3
  • 31
    • 48249128273 scopus 로고    scopus 로고
    • Individual crypt genetic heterogeneity and origin of metaplastic glandular epithelium in human Barrett' esophagus
    • Leedham, S.J., S.L. Preston, S.A.C. Mcdonald, et al 2008. Individual crypt genetic heterogeneity and origin of metaplastic glandular epithelium in human Barrett' esophagus. Gut 57: 1041-1048.
    • (2008) Gut , vol.57 , pp. 1041-1048
    • Leedham, S.J.1    Preston, S.L.2    Mcdonald, S.A.C.3
  • 32
    • 22644431730 scopus 로고    scopus 로고
    • On the histiogenesis of Barrett's esophagus and its associated squamous islands: a three-dimensional study of their morphological relationship with native esophageal gland ducts
    • Coad, R.A., A.C. Woodman, P.J. Warner, et al 2005. On the histiogenesis of Barrett's esophagus and its associated squamous islands: a three-dimensional study of their morphological relationship with native esophageal gland ducts. J. Pathol. 25: 388-394.
    • (2005) J. Pathol. , vol.25 , pp. 388-394
    • Coad, R.A.1    Woodman, A.C.2    Warner, P.J.3
  • 33
    • 34249668293 scopus 로고    scopus 로고
    • Characterization of telomerase- immortalized, non-neoplastic, human Barrett's cell line (BAR-T)
    • Jaiswal, K.R., C.P. Morales, L.A. Feagins, et al 2007. Characterization of telomerase- immortalized, non-neoplastic, human Barrett's cell line (BAR-T). Dis. Esophagus. 20: 256-264.
    • (2007) Dis. Esophagus. , vol.20 , pp. 256-264
    • Jaiswal, K.R.1    Morales, C.P.2    Feagins, L.A.3
  • 34
    • 0038576447 scopus 로고    scopus 로고
    • Gastric intestinal metaplasia as detected by a monoclonal antibody is highly associated with gastric adenocarcinoma
    • Mirza, Z.K., K.K. Das, J. Slate, et al. 2003. Gastric intestinal metaplasia as detected by a monoclonal antibody is highly associated with gastric adenocarcinoma. Gut. 52: 807-812.
    • (2003) Gut. , vol.52 , pp. 807-812
    • Mirza, Z.K.1    Das, K.K.2    Slate, J.3
  • 35
    • 0028280219 scopus 로고    scopus 로고
    • Detection of a shared colon epithelial epitope on Barrett epithelium by a novel monoclonal antibody
    • Das, K.M., I. Prasad, S. Garla & P.S. Amenta Detection of a shared colon epithelial epitope on Barrett epithelium by a novel monoclonal antibody. Ann. Intern. Med. 120: 753-756.
    • Ann. Intern. Med. , vol.120 , pp. 753-756
    • Das, K.M.1    Prasad, I.2    Garla, S.3    Amenta, P.S.4
  • 36
    • 44349187242 scopus 로고    scopus 로고
    • Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line
    • Bajpai, M., J. Liu, X. Geng, et al 2008. Repeated exposure to acid and bile selectively induces colonic phenotype expression in a heterogeneous Barrett's epithelial cell line. Lab Invest 88: 643-651.
    • (2008) Lab Invest , vol.88 , pp. 643-651
    • Bajpai, M.1    Liu, J.2    Geng, X.3
  • 37
    • 80053206297 scopus 로고    scopus 로고
    • Transformation of benign barrett's epithelium by repeated acid and bile exposure over 65 weeks: a novel in-vitro model
    • Das, K.M., Y. Kong, M. Bajpai, et al 2010. Transformation of benign barrett's epithelium by repeated acid and bile exposure over 65 weeks: a novel in-vitro model. Int. J. Cancer. 22.
    • (2010) Int. J. Cancer. , vol.22
    • Das, K.M.1    Kong, Y.2    Bajpai, M.3
  • 38
    • 28544439939 scopus 로고    scopus 로고
    • High cyclooxygenase-2 expression following neoadjuvant radiochemotherapy is associated with minor histopathologic response and poor prognosis in esophageal cancer
    • Xi, H., S.E. Baldus, U. Warnecke-Eberz, et al 2005. High cyclooxygenase-2 expression following neoadjuvant radiochemotherapy is associated with minor histopathologic response and poor prognosis in esophageal cancer. Clin. Cancer Res. 11: 8341-8347.
    • (2005) Clin. Cancer Res. , vol.11 , pp. 8341-8347
    • Xi, H.1    Baldus, S.E.2    Warnecke-Eberz, U.3
  • 39
    • 33644823793 scopus 로고    scopus 로고
    • Gene expression profiling of localized esophageal carcinomas: association with pathologic response to preoperative chemoradiation
    • Luthra, R, T.T. Wu, M.G. Luthra, et al 2006. Gene expression profiling of localized esophageal carcinomas: association with pathologic response to preoperative chemoradiation. J. Clin. Oncol. 24: 259-267.
    • (2006) J. Clin. Oncol. , vol.24 , pp. 259-267
    • Luthra, R.1    Wu, T.T.2    Luthra, M.G.3
  • 40
    • 77951693104 scopus 로고    scopus 로고
    • Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus
    • Lurje, G., J.M. Leers, A. Pohl, et al 2010. Genetic variations in angiogenesis pathway genes predict tumor recurrence in localized adenocarcinoma of the esophagus. Ann. Surg. 251: 857-864.
    • (2010) Ann. Surg. , vol.251 , pp. 857-864
    • Lurje, G.1    Leers, J.M.2    Pohl, A.3
  • 41
    • 39649094503 scopus 로고    scopus 로고
    • Alterations in Barrett's-related adenocarcinomas: a proteomic approach
    • Peng, D., E.A. Sheta, S.M. Powell, et al 2008. Alterations in Barrett's-related adenocarcinomas: a proteomic approach. Int. J. Cancer 122: 1303-1310.
    • (2008) Int. J. Cancer , vol.122 , pp. 1303-1310
    • Peng, D.1    Sheta, E.A.2    Powell, S.M.3
  • 42
    • 55249096894 scopus 로고    scopus 로고
    • Comprehensive mass- spectrometry-based proteome quantification of haploid versus diploid yeast
    • de Godoy, L.M., J.V. Olsen, J. Cox, et al 2008. Comprehensive mass- spectrometry-based proteome quantification of haploid versus diploid yeast. Nature 455: 1251-1254.
    • (2008) Nature , vol.455 , pp. 1251-1254
    • de Godoy, L.M.1    Olsen, J.V.2    Cox, J.3
  • 43
    • 29244432794 scopus 로고    scopus 로고
    • Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium
    • Kazumori, H., S. Ishihara, M.A. Rumi, et al. 2006. Bile acids directly augment caudal related homeobox gene Cdx2 expression in oesophageal keratinocytes in Barrett's epithelium. Gut. 55: 16-25.
    • (2006) Gut. , vol.55 , pp. 16-25
    • Kazumori, H.1    Ishihara, S.2    Rumi, M.A.3
  • 44
    • 77953556073 scopus 로고    scopus 로고
    • Acid and bile salt-induced CDX2 expression differs in esophageal squamous cells from patients with and without Barrett's esophagus
    • Huo, X., H.Y. Zhang, X.I. Zhang, et al Acid and bile salt-induced CDX2 expression differs in esophageal squamous cells from patients with and without Barrett's esophagus. Gastroenterology 139: 194-203 e191.
    • Gastroenterology , vol.139
    • Huo, X.1    Zhang, H.Y.2    Zhang, X.I.3
  • 45
    • 66349110898 scopus 로고    scopus 로고
    • Roles of caudal-related homeobox gene Cdx1 in oesophageal epithelial cells in Barrett's epithelium development
    • Kazumori, H., S. Ishihara & Y. Kinoshita 2009. Roles of caudal-related homeobox gene Cdx1 in oesophageal epithelial cells in Barrett's epithelium development. Gut. 58: 620-628.
    • (2009) Gut. , vol.58 , pp. 620-628
    • Kazumori, H.1    Ishihara, S.2    Kinoshita, Y.3
  • 46
    • 55849117334 scopus 로고    scopus 로고
    • Cdx1 and c- Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus
    • Stairs, D.B., H. Nakagawa, A. Klein-Szanto, et al 2008. Cdx1 and c- Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. PLoS One 3: e3534.
    • (2008) PLoS One , vol.3
    • Stairs, D.B.1    Nakagawa, H.2    Klein-Szanto, A.3
  • 47
    • 77951684109 scopus 로고    scopus 로고
    • Aberrant epithelial- mesenchymal Hedgehog signaling characterizes Barrett's metaplasia
    • Wang, D.H., N.J. Clemons, T. Miyashita, et al. Aberrant epithelial- mesenchymal Hedgehog signaling characterizes Barrett's metaplasia. Gastroenterology 138: 1810-1822.
    • Gastroenterology , vol.138 , pp. 1810-1822
    • Wang, D.H.1    Clemons, N.J.2    Miyashita, T.3
  • 48
    • 26844542497 scopus 로고    scopus 로고
    • A comparative analysis by SAGE of gene expression profiles of Barrett's esophagus, normal squamous esophagus, and gastric cardia
    • van Baal, J.W., F. Milano, A. Rygiel, et al 2005. A comparative analysis by SAGE of gene expression profiles of Barrett's esophagus, normal squamous esophagus, and gastric cardia. Gastroenterology 129: 1274-1281.
    • (2005) Gastroenterology , vol.129 , pp. 1274-1281
    • van Baal, J.W.1    Milano, F.2    Rygiel, A.3
  • 49
    • 34249982283 scopus 로고    scopus 로고
    • Bone morphogenetic protein 4 expressed in esophagitis induces a columnar phenotype in esophageal squamous cells
    • Milano, F., J.W. Van Baal, N.S. Buttar, et al. 2007. Bone morphogenetic protein 4 expressed in esophagitis induces a columnar phenotype in esophageal squamous cells. Gastroenterology 132: 2412-2421.
    • (2007) Gastroenterology , vol.132 , pp. 2412-2421
    • Milano, F.1    Van Baal, J.W.2    Buttar, N.S.3
  • 50
    • 34249668293 scopus 로고    scopus 로고
    • Characterization of telomerase-immortalized, non-neoplastic, human Barrett's cell line (BAR-T) Dis
    • Jaiswal, K.R., C.P. Morales, L.A. Feagins, et al 2007. Characterization of telomerase-immortalized, non-neoplastic, human Barrett's cell line (BAR-T) Dis. Esophagus. 20: 256-264.
    • (2007) Esophagus. , vol.20 , pp. 256-264
    • Jaiswal, K.R.1    Morales, C.P.2    Feagins, L.A.3
  • 51
    • 77956997434 scopus 로고    scopus 로고
    • Acid-induced p16 hypermethylation contributes to development of esophageal adenocarcinoma via activation of NADPH oxidase NOX5-S
    • Hong, J., M. Resnick, J. Behar, et al 2010. Acid-induced p16 hypermethylation contributes to development of esophageal adenocarcinoma via activation of NADPH oxidase NOX5-S. Am. J. Physiol. Gastrointest. Liver Physiol. 299: G697-G706.
    • (2010) Am. J. Physiol. Gastrointest. Liver Physiol. , vol.299
    • Hong, J.1    Resnick, M.2    Behar, J.3
  • 52
    • 0029907124 scopus 로고    scopus 로고
    • Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model
    • Fitzgerald, R.C., M.B. Omary & G. Triadafilopoulos 1996. Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model. J. Clin. Invest. 98: 2120-2128.
    • (1996) J. Clin. Invest. , vol.98 , pp. 2120-2128
    • Fitzgerald, R.C.1    Omary, M.B.2    Triadafilopoulos, G.3
  • 53
    • 34548710859 scopus 로고    scopus 로고
    • In Non-neoplastic Barrett's epithelial cells, acid exerts early antiproliferative effects through activation of the Chk2 pathway
    • Zhang, H.Y., X. Zhang, K. Hormi-Carver, et al 2007. In Non-neoplastic Barrett's epithelial cells, acid exerts early antiproliferative effects through activation of the Chk2 pathway. Cancer Res. 67: 8580-8587.
    • (2007) Cancer Res. , vol.67 , pp. 8580-8587
    • Zhang, H.Y.1    Zhang, X.2    Hormi-Carver, K.3
  • 54
    • 20044371170 scopus 로고    scopus 로고
    • Apoptosis resistance in Barrett's esophagus: ex vivo bioassay of live stressed tissues
    • Dvorakova, K., C.M. Payne, L. Ramsey, et al 2005. Apoptosis resistance in Barrett's esophagus: ex vivo bioassay of live stressed tissues. Am. J. Gastroenterol. 100: 424-431.
    • (2005) Am. J. Gastroenterol. , vol.100 , pp. 424-431
    • Dvorakova, K.1    Payne, C.M.2    Ramsey, L.3
  • 55
    • 0035908491 scopus 로고    scopus 로고
    • Phases of biomarker development for early detection of cancer
    • Pepe, M.S., R. Etzioni, Z. Feng, et al 2001. Phases of biomarker development for early detection of cancer. J. Natl. Cancer Inst. 93: 1054-1061.
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 1054-1061
    • Pepe, M.S.1    Etzioni, R.2    Feng, Z.3
  • 56
    • 0035180041 scopus 로고    scopus 로고
    • Predictors of progression in Barrett's esophagus: baseline flow cytometric variables
    • Rabinovitch, P.S., G. Longton, P.L. Blount, et al 2001. Predictors of progression in Barrett's esophagus: baseline flow cytometric variables. Am. J. Gastroenterol. 96: 3071-3083.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 3071-3083
    • Rabinovitch, P.S.1    Longton, G.2    Blount, P.L.3
  • 57
    • 0034793846 scopus 로고    scopus 로고
    • Predictors of progression in Barrett's esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression
    • Reid, B.J., L.J. Prevo, P.C. Agalipeau, et al 2001. Predictors of progression in Barrett's esophagus II: baseline 17p (p53) loss of heterozygosity identifies a patient subset at increased risk for neoplastic progression. Am. J. Gastroenterol. 96: 2839-2848.
    • (2001) Am. J. Gastroenterol. , vol.96 , pp. 2839-2848
    • Reid, B.J.1    Prevo, L.J.2    Agalipeau, P.C.3
  • 58
    • 5644255657 scopus 로고    scopus 로고
    • The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma
    • Maley, C.C., P.C. Galipeau, X. Li, et al 2004. The combination of genetic instability and clonal expansion predicts progression to esophageal adenocarcinoma. Cancer Res. 64: 7629-7633.
    • (2004) Cancer Res. , vol.64 , pp. 7629-7633
    • Maley, C.C.1    Galipeau, P.C.2    Li, X.3
  • 59
    • 80053199140 scopus 로고    scopus 로고
    • Cdx genes, inflammation, and the pathogenesis of intestinal metaplasias
    • In K. Kaestner, Ed. In Press, Elsevier .
    • Stairs, D.B., J. Kong, & J.P. Lynch, Cdx genes, inflammation, and the pathogenesis of intestinal metaplasias, In Molecular Biology of Digestive Organs. K. Kaestner, Ed. In Press, Elsevier .
    • Molecular Biology of Digestive Organs
    • Stairs, D.B.1    Kong, J.2    Lynch, J.P.3
  • 60
    • 66149115211 scopus 로고    scopus 로고
    • Molecular markers and genetics in cancer development
    • Hormi-Carver, K. & R.F. Souza 2009. Molecular markers and genetics in cancer development. Surg. Oncol. Clin. N. Am. 18: 453-467.
    • (2009) Surg. Oncol. Clin. N. Am. , vol.18 , pp. 453-467
    • Hormi-Carver, K.1    Souza, R.F.2
  • 61
    • 77952305665 scopus 로고    scopus 로고
    • The p53 tumor suppressor: a master regulator of diverse cellular processes and therapeutic target in cancer
    • Farnebo, M., V.J. Bykov, & K.G. Wiman 2010. The p53 tumor suppressor: a master regulator of diverse cellular processes and therapeutic target in cancer. Biochem. Biophys. Res. Commun. 396: 85-89.
    • (2010) Biochem. Biophys. Res. Commun. , vol.396 , pp. 85-89
    • Farnebo, M.1    Bykov, V.J.2    Wiman, K.G.3
  • 62
    • 0034614637 scopus 로고    scopus 로고
    • The hallmarks of cancer
    • Hanahan, D. & R.A. Weinberg 2000. The hallmarks of cancer. Cell 100: 57-70.
    • (2000) Cell , vol.100 , pp. 57-70
    • Hanahan, D.1    Weinberg, R.A.2
  • 63
    • 77954424806 scopus 로고    scopus 로고
    • Predictors of progression in Barrett's esophagus: current knowledge and future directions
    • Prasad, G.A., et al Predictors of progression in Barrett's esophagus: current knowledge and future directions. Am. J. Gastroenterol. 105: 1490-1502.
    • Am. J. Gastroenterol. , vol.105 , pp. 1490-1502
    • Prasad, G.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.