메뉴 건너뛰기




Volumn 98, Issue 9, 1996, Pages 2120-2128

Dynamic effects of acid on Barrett's esophagus. An ex vivo proliferation and differentiation model

Author keywords

brush border; gastroesophageal reflux; intestinal metaplasia; villin

Indexed keywords

CYCLINE; VILLIN;

EID: 0029907124     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI119018     Document Type: Article
Times cited : (305)

References (66)
  • 1
    • 0000051338 scopus 로고
    • The lower esophagus lined by columnar epithelium
    • Barrett, N.R. 1957. The lower esophagus lined by columnar epithelium. Surgery (St. Louis). 41:881-894.
    • (1957) Surgery (St. Louis) , vol.41 , pp. 881-894
    • Barrett, N.R.1
  • 3
    • 0026039730 scopus 로고
    • Barrett's esophagus and esophageal adenocarcinoma
    • Reid, B.J. 1991. Barrett's esophagus and esophageal adenocarcinoma. Gastroenterol. Clin. N. Am. 20:817-834.
    • (1991) Gastroenterol. Clin. N. Am. , vol.20 , pp. 817-834
    • Reid, B.J.1
  • 4
    • 0027993158 scopus 로고
    • Barrett's esophagus, dysplasia, and adenocarcinoma
    • Haggitt, R.C. 1994. Barrett's esophagus, dysplasia, and adenocarcinoma. Hum. Pathol. 25:982-993.
    • (1994) Hum. Pathol. , vol.25 , pp. 982-993
    • Haggitt, R.C.1
  • 5
    • 0030040665 scopus 로고    scopus 로고
    • The columnar-lined esophagus, intestinal metaplasia, and Norman Barrett
    • Spechler, S.J., and R.J. Goyal. 1996. The columnar-lined esophagus, intestinal metaplasia, and Norman Barrett. Gastroenterology. 110:614-621.
    • (1996) Gastroenterology , vol.110 , pp. 614-621
    • Spechler, S.J.1    Goyal, R.J.2
  • 6
    • 0022003991 scopus 로고
    • Barrett's esophagus: Its prevalence and association with adenocarcinoma in patients with symptoms of gastroesophageal reflux
    • Sarr, M.G., S.R. Hamilton, G.C. Marrone, and J.L. Cameron. 1985. Barrett's esophagus: its prevalence and association with adenocarcinoma in patients with symptoms of gastroesophageal reflux. Am. J. Surg. 149:187-193.
    • (1985) Am. J. Surg. , vol.149 , pp. 187-193
    • Sarr, M.G.1    Hamilton, S.R.2    Marrone, G.C.3    Cameron, J.L.4
  • 7
    • 0026028040 scopus 로고
    • Rising incidence of adenocarcinoma of the esophagus and gastric cardia
    • Blot, W.J., S.S. Devesa, R.W. Kneller, and J.F. Fraumeni, Jr. 1991. Rising incidence of adenocarcinoma of the esophagus and gastric cardia. J. Am. Med. Assoc. 265:1287-1289.
    • (1991) J. Am. Med. Assoc. , vol.265 , pp. 1287-1289
    • Blot, W.J.1    Devesa, S.S.2    Kneller, R.W.3    Fraumeni Jr., J.F.4
  • 8
    • 0027302718 scopus 로고
    • An endoscopie biopsy protocol can differentiate high-grade dysplasia from early adenocarcinoma in Barrett's esophagus
    • Levine, D.S., R.C. Haggitt, P.L. Blount, P.S. Rabinovitch, V.W. Rusch, and B. Reid. 1993. An endoscopie biopsy protocol can differentiate high-grade dysplasia from early adenocarcinoma in Barrett's esophagus. Gastroenterology. 105:40-50.
    • (1993) Gastroenterology , vol.105 , pp. 40-50
    • Levine, D.S.1    Haggitt, R.C.2    Blount, P.L.3    Rabinovitch, P.S.4    Rusch, V.W.5    Reid, B.6
  • 9
    • 0026643230 scopus 로고
    • Reflux and motility pattern in Barrett's esophagus
    • Stein, H.J., S. Hoeft, and T.R. DeMeester. 1992. Reflux and motility pattern in Barrett's esophagus. Dis. Esoph. 5:21-28.
    • (1992) Dis. Esoph. , vol.5 , pp. 21-28
    • Stein, H.J.1    Hoeft, S.2    Demeester, T.R.3
  • 12
    • 0027394782 scopus 로고
    • Role of reflux oesophagitis and acid in the development of columnar epithelium in the rat oesophagus
    • Seto, Y., and O. Kobori. 1993. Role of reflux oesophagitis and acid in the development of columnar epithelium in the rat oesophagus. Br. J. Surg. 80: 467-470.
    • (1993) Br. J. Surg. , vol.80 , pp. 467-470
    • Seto, Y.1    Kobori, O.2
  • 13
    • 0027976819 scopus 로고
    • Mechanisms of columnar metaplasia and squamous regeneration in experimental Barrett's esophagus
    • Hui, Li., T.N. Walsh, G. O'Dowd, P. Gillen, P.J. Byrne, and T.P.J. Hennessy. 1992. Mechanisms of columnar metaplasia and squamous regeneration in experimental Barrett's esophagus. Surgery (St. Louis). 115:176-181.
    • (1992) Surgery (St. Louis) , vol.115 , pp. 176-181
    • Hui, L.1    Walsh, T.N.2    O'Dowd, G.3    Gillen, P.4    Byrne, P.J.5    Hennessy, T.P.J.6
  • 15
    • 0028054143 scopus 로고
    • Effect of up to 3 years of high-dose lansoprazole on Barrett's esophagus
    • Sampliner, R.E. 1994. Effect of up to 3 years of high-dose lansoprazole on Barrett's esophagus. Am. J. Gastroenterol. 89:1844-1848.
    • (1994) Am. J. Gastroenterol. , vol.89 , pp. 1844-1848
    • Sampliner, R.E.1
  • 16
    • 0025037553 scopus 로고
    • Gastric acid hypersecretion in refractory gastroesophageal reflux disease
    • Collen, M.J., J.H. Lewis, and S.B. Benjamin. 1990. Gastric acid hypersecretion in refractory gastroesophageal reflux disease. Gastroenterology. 98:654-661.
    • (1990) Gastroenterology , vol.98 , pp. 654-661
    • Collen, M.J.1    Lewis, J.H.2    Benjamin, S.B.3
  • 17
    • 0024573523 scopus 로고
    • Specialized metaplastic columnar epithelium in Barrett's esophagus: A comparative transmission electron microscopic study
    • Levine, D.S., C.E. Rubin, B.J. Reid, and R. Haggitt. 1989. Specialized metaplastic columnar epithelium in Barrett's esophagus: a comparative transmission electron microscopic study. Lab. Invest. 60:418-432.
    • (1989) Lab. Invest. , vol.60 , pp. 418-432
    • Levine, D.S.1    Rubin, C.E.2    Reid, B.J.3    Haggitt, R.4
  • 18
    • 0029985644 scopus 로고    scopus 로고
    • Multifocal heterogeneity in villin and Ep-cam expression in Barrett's esophagus
    • Kumble, S., M.B. Omary, L.F. Fajardo, and G. Triadafilopoulos. 1996. Multifocal heterogeneity in villin and Ep-cam expression in Barrett's esophagus. Int. J. Cancer. 66:48-54.
    • (1996) Int. J. Cancer. , vol.66 , pp. 48-54
    • Kumble, S.1    Omary, M.B.2    Fajardo, L.F.3    Triadafilopoulos, G.4
  • 19
    • 85035182458 scopus 로고    scopus 로고
    • Upregulation of src in premalignant Barrett's esophagus and esophageal adenocarcinoma
    • In press
    • Kumble, S., C. Cartwright, B. Omary, and G. Triadafilopoulos. 1996. Upregulation of src in premalignant Barrett's esophagus and esophageal adenocarcinoma. Gastroenterology. 110:A547. In press.
    • (1996) Gastroenterology , vol.110
    • Kumble, S.1    Cartwright, C.2    Omary, B.3    Triadafilopoulos, G.4
  • 20
    • 0023840926 scopus 로고
    • Endoscopic biopsies diagnose high grade dysplasia or early operable adenocarcinoma without grossly recognizable neoplastic lesions
    • Reid, B.J., W.M. Weinstein, K.J. Lewin, R.C. Haggilt, G. Van Deventer, L. Den Besten, and C.E. Rubin. 1988. Endoscopic biopsies diagnose high grade dysplasia or early operable adenocarcinoma without grossly recognizable neoplastic lesions. Gastroenterology. 94:81-90.
    • (1988) Gastroenterology , vol.94 , pp. 81-90
    • Reid, B.J.1    Weinstein, W.M.2    Lewin, K.J.3    Haggilt, R.C.4    Van Deventer, G.5    Den Besten, L.6    Rubin, C.E.7
  • 21
    • 0029979657 scopus 로고    scopus 로고
    • Origin of atypical reflux symptoms. A case study showing the importance of reflux composition and posture
    • Shay, S.S., and J.E. Richter. 1996. Origin of atypical reflux symptoms. A case study showing the importance of reflux composition and posture. Dig. Dis. Sci. 41:505-511.
    • (1996) Dig. Dis. Sci. , vol.41 , pp. 505-511
    • Shay, S.S.1    Richter, J.E.2
  • 22
    • 0017201973 scopus 로고
    • Patterns of gastroesophageal reflux in health and disease
    • DeMeester, T.R., L.F. Johnson, J.I. Guy et al. 1976. Patterns of gastroesophageal reflux in health and disease. Ann. Surg. 184:459-470.
    • (1976) Ann. Surg. , vol.184 , pp. 459-470
    • Demeester, T.R.1    Johnson, L.F.2    Guy, J.I.3
  • 23
    • 0024340184 scopus 로고
    • Does the intraesophageal pH probe accurately detect acid reflux? Simultaneous recording with two pH probes in humans
    • Murphy, D.W., Y. Yuan, and D.O. Castell. 1989. Does the intraesophageal pH probe accurately detect acid reflux? Simultaneous recording with two pH probes in humans. Dig. Dis. Sci. 34:649-656.
    • (1989) Dig. Dis. Sci. , vol.34 , pp. 649-656
    • Murphy, D.W.1    Yuan, Y.2    Castell, D.O.3
  • 24
    • 0018578513 scopus 로고
    • Identification and organization of the compartments of the isolated microvillus cytoskeleton
    • Matsudaira, P.T., and D.R. Burgess. 1979. Identification and organization of the compartments of the isolated microvillus cytoskeleton. J. Cell Biol. 83:667-673.
    • (1979) J. Cell Biol. , vol.83 , pp. 667-673
    • Matsudaira, P.T.1    Burgess, D.R.2
  • 25
    • 0018869290 scopus 로고
    • Villin is a major protein of microvillus cytoskeleton which binds G and F actin in a calcium-dependent manner
    • Bretscher, A., and K. Weber. 1980. Villin is a major protein of microvillus cytoskeleton which binds G and F actin in a calcium-dependent manner. Cell. 20:839-847.
    • (1980) Cell. , vol.20 , pp. 839-847
    • Bretscher, A.1    Weber, K.2
  • 26
    • 0022172245 scopus 로고
    • Organization, chemistry and assembly of the cytoskeletal apparatus of the intestinal brush border
    • Mooseker, M.S. 1985. Organization, chemistry and assembly of the cytoskeletal apparatus of the intestinal brush border. Annu. Rev. Cell Biol. 1:209-241.
    • (1985) Annu. Rev. Cell Biol. , vol.1 , pp. 209-241
    • Mooseker, M.S.1
  • 28
    • 0023376195 scopus 로고
    • Assembly of the intestinal brush border: Appearance and redistribution of microvillar core proteins in developing chick enterocytes
    • Shibayama, T., J.M. Carboni, and M.S. Mooseker. 1987. Assembly of the intestinal brush border: appearance and redistribution of microvillar core proteins in developing chick enterocytes. J. Cell Biol. 105:335-344.
    • (1987) J. Cell Biol. , vol.105 , pp. 335-344
    • Shibayama, T.1    Carboni, J.M.2    Mooseker, M.S.3
  • 29
    • 0019867871 scopus 로고
    • Villin associates with specific microfilamentous structures as seen by immunofluorescence microscopy on tissue sections and cells microinjected with villin
    • Bretscher, A., A. Osborn, J. Wehland, and K. Weber. 1981. Villin associates with specific microfilamentous structures as seen by immunofluorescence microscopy on tissue sections and cells microinjected with villin. Exp. Cell. Res. 135:213-219.
    • (1981) Exp. Cell. Res. , vol.135 , pp. 213-219
    • Bretscher, A.1    Osborn, A.2    Wehland, J.3    Weber, K.4
  • 30
    • 0024317269 scopus 로고
    • Villin induces microvilli growth and actin redistribution in transfected fibroblasts
    • Friederich, E., C. Huet, M. Arpin, and D. Louvard. 1989. Villin induces microvilli growth and actin redistribution in transfected fibroblasts. Cell. 59: 461-475.
    • (1989) Cell , vol.59 , pp. 461-475
    • Friederich, E.1    Huet, C.2    Arpin, M.3    Louvard, D.4
  • 31
    • 0028821179 scopus 로고
    • Suppression of villin expression by antisense RNA on brush border assembly in polarized epithelial intestinal cells
    • De Beauregard, M.C., E. Pringault, S. Robine, and D. Louvard. 1995. Suppression of villin expression by antisense RNA on brush border assembly in polarized epithelial intestinal cells. EMBO (Eur. Mol. Biol. Organ.) J. 14:409-421.
    • (1995) EMBO (Eur. Mol. Biol. Organ.) J. , vol.14 , pp. 409-421
    • De Beauregard, M.C.1    Pringault, E.2    Robine, S.3    Louvard, D.4
  • 32
    • 0022988978 scopus 로고
    • Human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo
    • Pringault, E., M. Arpin, A. Garcia, A. Findori, and D.A. Louvard. 1986. Human villin cDNA clone to investigate the differentiation of intestinal and kidney cells in vivo. EMBO (Eur. Mol. Biol. Organ.) J. 5:3119-3124.
    • (1986) EMBO (Eur. Mol. Biol. Organ.) J. , vol.5 , pp. 3119-3124
    • Pringault, E.1    Arpin, M.2    Garcia, A.3    Findori, A.4    Louvard, D.A.5
  • 33
    • 0018863946 scopus 로고
    • Organ culture of the mucosa of human small intestine
    • Trier, J.S. 1980. Organ culture of the mucosa of human small intestine. Methods Cell Biol. 18:365-384.
    • (1980) Methods Cell Biol. , vol.18 , pp. 365-384
    • Trier, J.S.1
  • 34
    • 0343562554 scopus 로고
    • Organ culture
    • Freshney R.I. editor, Rickwood D., and Hames B.D., series editors. IRL Press at Oxford University Press, New York
    • Lasnitzki, I. 1992. Organ culture. In Animal Cell Culture, a Practical Approach. Freshney R.I. editor, Rickwood D., and Hames B.D., series editors. IRL Press at Oxford University Press, New York, 213-261.
    • (1992) Animal Cell Culture, a Practical Approach , pp. 213-261
    • Lasnitzki, I.1
  • 35
    • 0023738916 scopus 로고
    • A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumour necrosis factor (TNF) activity
    • Decker, T., and M.L. Lohtnann-Matthes. 1988. A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumour necrosis factor (TNF) activity. J. Immunol. Methods. 15:61-69.
    • (1988) J. Immunol. Methods. , vol.15 , pp. 61-69
    • Decker, T.1    Lohtnann-Matthes, M.L.2
  • 36
    • 0016169108 scopus 로고
    • Dysplasia in inflammatory bowel disease
    • Ismail-Beigi, F., and C.E. Pope. 1974. Dysplasia in inflammatory bowel disease. Gastroenterology. 66:1109-1113.
    • (1974) Gastroenterology , vol.66 , pp. 1109-1113
    • Ismail-Beigi, F.1    Pope, C.E.2
  • 37
    • 0021017589 scopus 로고
    • Dysplasia in inflammatory bowel disease: Standardized classification with provisional applications
    • Riddell, R.H., et al. 1983. Dysplasia in inflammatory bowel disease: standardized classification with provisional applications. Hum. Pathol. 14:931-968.
    • (1983) Hum. Pathol. , vol.14 , pp. 931-968
    • Riddell, R.H.1
  • 38
    • 0022479224 scopus 로고
    • Histological and histochemical changes in the columnar-lined (Barrett's) esophagus
    • Rothery, G.A., J.E. Patterson, C.J. Stoddard, and D.W. Day. 1986. Histological and histochemical changes in the columnar-lined (Barrett's) esophagus. Gut. 27:1062-1068.
    • (1986) Gut. , vol.27 , pp. 1062-1068
    • Rothery, G.A.1    Patterson, J.E.2    Stoddard, C.J.3    Day, D.W.4
  • 39
    • 0026454961 scopus 로고
    • Epithelial proliferation in Barrett's esophagus by proliferating cell nuclear antigen immunolocalization
    • Gray, M.R., P.A. Hall, J. Nash, B. Ansari, P.L. Lane, and A.N. Kingsworth. 1992. Epithelial proliferation in Barrett's esophagus by proliferating cell nuclear antigen immunolocalization. Gastroenterology. 103:1769-1776.
    • (1992) Gastroenterology , vol.103 , pp. 1769-1776
    • Gray, M.R.1    Hall, P.A.2    Nash, J.3    Ansari, B.4    Lane, P.L.5    Kingsworth, A.N.6
  • 40
    • 0014561779 scopus 로고
    • Organ culture of mucosal biopsies of human small intestine
    • Browning, T.H., and J.S. Trier. 1969. Organ culture of mucosal biopsies of human small intestine. J. Clin. Invest. 48:1423-1433.
    • (1969) J. Clin. Invest. , vol.48 , pp. 1423-1433
    • Browning, T.H.1    Trier, J.S.2
  • 42
    • 0026091353 scopus 로고
    • Moesin: A member of the protein 4.1-talin-ezrin family of proteins
    • Lankes, W., and H. Furthmayr. 1991. Moesin: a member of the protein 4.1-talin-ezrin family of proteins. Proc. Natl. Acad. Sci. USA. 88:8297-8301.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8297-8301
    • Lankes, W.1    Furthmayr, H.2
  • 43
    • 0021221530 scopus 로고
    • Organ culture of gastrointestinal mucosa - A technique for the study of the human gastrointestinal tract
    • Howdle, P.D. 1984. Organ culture of gastrointestinal mucosa - a technique for the study of the human gastrointestinal tract. J. Postgrad. Med. 69: 645-652.
    • (1984) J. Postgrad. Med. , vol.69 , pp. 645-652
    • Howdle, P.D.1
  • 44
    • 0018844287 scopus 로고
    • Cell proliferation in three types of Barrett's epithelium
    • Pellish, L.P., J.A. Hermos, and G.L. Eastwood. 1980. Cell proliferation in three types of Barrett's epithelium. Gut. 21:26-31.
    • (1980) Gut. , vol.21 , pp. 26-31
    • Pellish, L.P.1    Hermos, J.A.2    Eastwood, G.L.3
  • 45
    • 0018119911 scopus 로고
    • Cell proliferation in esophageal columnar epithelium (Barrett's esophagus)
    • Herbst, J.J., M.M. Berenson, D.W. McCloskey, and W.C. Wiser 1978. Cell proliferation in esophageal columnar epithelium (Barrett's esophagus). Gastroenterology. 75:683-687.
    • (1978) Gastroenterology , vol.75 , pp. 683-687
    • Herbst, J.J.1    Berenson, M.M.2    McCloskey, D.W.3    Wiser, W.C.4
  • 46
    • 0027475245 scopus 로고
    • Cell proliferation, differentiation and cell death in epithelial cells of the esophagus; a critical review of biological markers and their applications to research and diagnosis
    • Jankowski, J., and R. Dover. 1993. Cell proliferation, differentiation and cell death in epithelial cells of the esophagus; a critical review of biological markers and their applications to research and diagnosis. Gullet. 3:1-15.
    • (1993) Gullet. , vol.3 , pp. 1-15
    • Jankowski, J.1    Dover, R.2
  • 47
    • 0021360017 scopus 로고
    • The brush border cytoskeleton is not static: In vivo turnover of proteins
    • Stidwill, R.P., T. Wysolmerski, and D.R. Burgess. 1984. The brush border cytoskeleton is not static: in vivo turnover of proteins. J. Cell Biol. 98:641-645.
    • (1984) J. Cell Biol. , vol.98 , pp. 641-645
    • Stidwill, R.P.1    Wysolmerski, T.2    Burgess, D.R.3
  • 49
    • 0024202668 scopus 로고
    • Differential distribution of villin and villin mRNA in mouse intestinal epithelial cells
    • Boller, K., M. Arpin, E. Pringault, and H. Reggio. 1988. Differential distribution of villin and villin mRNA in mouse intestinal epithelial cells. Differentiation. 39:51-57.
    • (1988) Differentiation , vol.39 , pp. 51-57
    • Boller, K.1    Arpin, M.2    Pringault, E.3    Reggio, H.4
  • 50
    • 0026773096 scopus 로고
    • An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin
    • Friederich, E., K. Vancompernolle, C. Huet, M. Goethals, J. Finidon, J. Vandejerckhove, and D. Louvard. 1992. An actin-binding site containing a conserved motif of charged amino acid residues is essential for the morphogenic effect of villin. Cell. 70:81-92.
    • (1992) Cell , vol.70 , pp. 81-92
    • Friederich, E.1    Vancompernolle, K.2    Huet, C.3    Goethals, M.4    Finidon, J.5    Vandejerckhove, J.6    Louvard, D.7
  • 52
    • 0022004311 scopus 로고
    • 2, and inhibition of endogenous prostaglandin synthesis on proximal duodenal bicarbonate secretion in unanesthetized rat
    • 2, and inhibition of endogenous prostaglandin synthesis on proximal duodenal bicarbonate secretion in unanesthetized rat. Gastroenterology. 88:303-307.
    • (1985) Gastroenterology , vol.88 , pp. 303-307
    • Isenberg, J.I.1    Smedors, B.2    Johansson, C.3
  • 53
    • 0020697766 scopus 로고
    • Introductory remarks on the brush border
    • Pitman Books Ltd, London
    • Parsons, D.S., 1983. Introductory remarks on the brush border. Ciba Foundation symposium. Pitman Books Ltd, London. 3-11.
    • (1983) Ciba Foundation Symposium , pp. 3-11
    • Parsons, D.S.1
  • 55
    • 0030052904 scopus 로고    scopus 로고
    • The membrane recruitment-and-recycling hypothesis of gastric HCl secretion
    • Forte, J.G., and Y. Xuebiao. 1996. The membrane recruitment-and-recycling hypothesis of gastric HCl secretion. Trends Cell Biol. 6:45-49.
    • (1996) Trends Cell Biol. , vol.6 , pp. 45-49
    • Forte, J.G.1    Xuebiao, Y.2
  • 56
    • 0030042643 scopus 로고    scopus 로고
    • From coiled tubules to a secretory canaliculus: A model for membrane transformation and acid secretion by gastric parietal cells
    • Pettit, J.M., I.R. Van Driel, T. Ben-Hock, and P.A. Gleeson. 1996. From coiled tubules to a secretory canaliculus: a model for membrane transformation and acid secretion by gastric parietal cells. Trends Cell Biol. 6:49-53.
    • (1996) Trends Cell Biol. , vol.6 , pp. 49-53
    • Pettit, J.M.1    Van Driel, I.R.2    Ben-Hock, T.3    Gleeson, P.A.4
  • 60
    • 0021930087 scopus 로고
    • Hydrochloric acid a trigger of cell proliferation in the esophagus of dogs
    • De Backer, A., P. Haentjens, and G. Willems. 1985. Hydrochloric acid a trigger of cell proliferation in the esophagus of dogs. Dig. Dis. Sci. 30:884-890.
    • (1985) Dig. Dis. Sci. , vol.30 , pp. 884-890
    • De Backer, A.1    Haentjens, P.2    Willems, G.3
  • 61
    • 0024594966 scopus 로고
    • Membrane mechanisms in volume and pH regulation in vertebrate cells
    • Hoffman, E.K., and L.O. Simonsen. 1989. Membrane mechanisms in volume and pH regulation in vertebrate cells. Physiological Rev. 69:315-378.
    • (1989) Physiological Rev. , vol.69 , pp. 315-378
    • Hoffman, E.K.1    Simonsen, L.O.2
  • 62
    • 0027176366 scopus 로고
    • Mechanisms of HCl-induced lowering of intracellular pH on rabbit esophageal epithelial cells
    • Tobey, N.A., P.R. Srighar, T.O. Keku, E.J. Cragoe, Jr., and R.C. Orlando. 1993. Mechanisms of HCl-induced lowering of intracellular pH on rabbit esophageal epithelial cells. Gastroenterology. 105:1035-1044.
    • (1993) Gastroenterology , vol.105 , pp. 1035-1044
    • Tobey, N.A.1    Srighar, P.R.2    Keku, T.O.3    Cragoe Jr., E.J.4    Orlando, R.C.5
  • 63
    • 0024286746 scopus 로고
    • Regulation of intracellular pH in eukaryotic cells
    • Madshus, I.H. 1988. Regulation of intracellular pH in eukaryotic cells. Biochem. J. 250:1-8.
    • (1988) Biochem. J. , vol.250 , pp. 1-8
    • Madshus, I.H.1
  • 64
    • 0023223937 scopus 로고
    • Intracellular pH is increased after transformation of Chinese hamster embryo fibroblasts
    • Ober, S.S., and A.B. Pardee 1987. Intracellular pH is increased after transformation of Chinese hamster embryo fibroblasts. Proc. Natl. Acad. Sci. USA. 84:2766-2770.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , pp. 2766-2770
    • Ober, S.S.1    Pardee, A.B.2
  • 65
    • 0025370064 scopus 로고
    • Clonal adaptation during carcinogenesis
    • Farber, E. 1990. Clonal adaptation during carcinogenesis. Biochem. Pharmacology. 39:1837-1846.
    • (1990) Biochem. Pharmacology , vol.39 , pp. 1837-1846
    • Farber, E.1
  • 66
    • 0026621194 scopus 로고
    • Adaptive mutagenesis - Cause of alimentary cancer
    • Wormsley, K.G. 1992. Adaptive mutagenesis - cause of alimentary cancer. Scand. J. Gastroenterol. 193S:68-75.
    • (1992) Scand. J. Gastroenterol. , vol.193 S , pp. 68-75
    • Wormsley, K.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.