Mutations responsible for MYH9-related thrombocytopenia impair SDF-1-driven migration of megakaryoblastic cells

Thrombosis and Haemostasis

Volumn 106, Issue 4, 2011, Pages 693-704

  Pecci, Alessandro ^a   Bozzi, Valeria ^a   Panza, Emanuele ^b,c   Barozzi, Serena ^a   Gruppi, Cristian ^a   Seri, Marco ^b   Balduini, Carlo L ^a  

^a UNIVERSITY OF PAVIA   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Cell migration; Inherited thrombocytopenia; MYH9 mutations; MYH9 related disease; Non muscle myosin IIA

Indexed keywords

ADENOSINE TRIPHOSPHATASE; COLLAGEN TYPE 1; FIBRINOGEN; MYOSIN IIA; MYOSIN IIA ATPASE; NONMUSCLE MYOSIN HEAVY CHAIN IIA; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG;

ARTICLE; AUTOSOMAL DOMINANT DISORDER; CELL MIGRATION; CELL SPREADING; CONTROLLED STUDY; ENZYME INHIBITION; GENE; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MEGAKARYOBLAST; MUTANT; MYH9 GENE; MYH9 RELATED THROMBOCYTOPENIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; THROMBOCYTOPENIA; WILD TYPE;

CELL ADHESION; CELL LINE; CHEMOKINE CXCL12; CHEMOTAXIS; CHROMOSOME BREAKAGE; CHROMOSOME DISORDERS; COLLAGEN TYPE I; CYTOSKELETON; EXTRACELLULAR MATRIX; HUMANS; MEGAKARYOCYTE PROGENITOR CELLS; MOLECULAR MOTOR PROTEINS; MUTATION; MYOSIN HEAVY CHAINS; THROMBOCYTOPENIA; THROMBOPOIESIS; TRANSGENES;

EID: 80053205810     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH11-02-0126     Document Type: Article

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