메뉴 건너뛰기




Volumn 26, Issue 11, 2011, Pages 1475-1486

Novel therapeutic strategies to target RCAS1, which induces apoptosis via ectodomain shedding

Author keywords

Apoptosis; Biomarker; Ectodomain shedding; RCAS1; Targeting therapy

Indexed keywords

EBAG9 PROTEIN, HUMAN; TUMOR ANTIGEN; TUMOR MARKER;

EID: 80053177112     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (13)

References (104)
  • 2
    • 43449094338 scopus 로고    scopus 로고
    • Is personalized medicine finally arriving?
    • Allison M. (2008). Is personalized medicine finally arriving? Nat. Biotechnol. 26, 509-517.
    • (2008) Nat. Biotechnol , vol.26 , pp. 509-517
    • Allison, M.1
  • 3
    • 6344261899 scopus 로고    scopus 로고
    • Soluble receptor-binding cancer antigen expressed on SiSo cells in pleural fluid: A potential diagnostic marker for malignant pleural effusion
    • Aoe K., Hiraki A., Maeda T., Murakami T., Yamazaki K., Sugi K. and Takeyama H. (2004). Soluble receptor-binding cancer antigen expressed on SiSo cells in pleural fluid: a potential diagnostic marker for malignant pleural effusion. Chest 126, 1195-1197.
    • (2004) Chest , vol.126 , pp. 1195-1197
    • Aoe, K.1    Hiraki, A.2    Maeda, T.3    Murakami, T.4    Yamazaki, K.5    Sugi, K.6    Takeyama, H.7
  • 7
    • 79955727135 scopus 로고    scopus 로고
    • The dual kinase complex FAK-Src as a promising therapeutic target in cancer
    • Bolos V., Gasent J.M., Lopez-Tarruella S. and Grande E. (2010). The dual kinase complex FAK-Src as a promising therapeutic target in cancer. OncoTargets Ther. 3, 83-97.
    • (2010) OncoTargets Ther , vol.3 , pp. 83-97
    • Bolos, V.1    Gasent, J.M.2    Lopez-Tarruella, S.3    Grande, E.4
  • 8
    • 0034488852 scopus 로고    scopus 로고
    • Interstitial collagenases as markers of tumor progression
    • Brinkerhoff C.E., Rutter J.L. and Benbow U. (2000). Interstitial collagenases as markers of tumor progression. Clin. Cancer Res. 6, 4823-4830.
    • (2000) Clin. Cancer Res , vol.6 , pp. 4823-4830
    • Brinkerhoff, C.E.1    Rutter, J.L.2    Benbow, U.3
  • 9
    • 0035020420 scopus 로고    scopus 로고
    • Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis
    • Byun Y., Chen F., Chang R., Trivedi M., Green K.J. and Cryns V.L. (2001). Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis. Cell Death Differ. 8, 443-450.
    • (2001) Cell Death Differ , vol.8 , pp. 443-450
    • Byun, Y.1    Chen, F.2    Chang, R.3    Trivedi, M.4    Green, K.J.5    Cryns, V.L.6
  • 11
    • 33750171074 scopus 로고    scopus 로고
    • The utility of serum receptor-binding cancer antigen expressed on SiSo cells in gastrointestinal tract cancers
    • Coban S., Ozkan H., Koklu S., Yuksel O., Kockar M.C., Akar T. and Ormeci N. (2006). The utility of serum receptor-binding cancer antigen expressed on SiSo cells in gastrointestinal tract cancers. Can. J. Gastroenterol. 20, 593-596.
    • (2006) Can. J. Gastroenterol , vol.20 , pp. 593-596
    • Coban, S.1    Ozkan, H.2    Koklu, S.3    Yuksel, O.4    Kockar, M.C.5    Akar, T.6    Ormeci, N.7
  • 12
    • 33644683263 scopus 로고    scopus 로고
    • Endothelial extracellular matrix. Biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization
    • Davis G.E. and Senger D.R. (2005). Endothelial extracellular matrix. Biosynthesis, remodeling, and functions during vascular morphogenesis and neovessel stabilization. Circ. Res. 97, 1093-1107.
    • (2005) Circ. Res , vol.97 , pp. 1093-1107
    • Davis, G.E.1    Senger, D.R.2
  • 13
    • 39149141375 scopus 로고    scopus 로고
    • The association of RCAS1 serum concentration with the reversibility or irreversibility of the process of immune cytotoxic activity restriction during normal menstrual cycle, cancer relapse, and surgical treatment for various types of squamous cell carcinomas and adenocarcinomas
    • Dutsch-Wicherek M. and Wicherek L. (2008). The association of RCAS1 serum concentration with the reversibility or irreversibility of the process of immune cytotoxic activity restriction during normal menstrual cycle, cancer relapse, and surgical treatment for various types of squamous cell carcinomas and adenocarcinomas. Am. J. Reprod. Immunol. 59, 266-275.
    • (2008) Am. J. Reprod. Immunol , vol.59 , pp. 266-275
    • Dutsch-Wicherek, M.1    Wicherek, L.2
  • 14
    • 60849121736 scopus 로고    scopus 로고
    • The association between RCAS1 expression in laryngeal and pharyngeal cancer and its healthy stroma with cancer relapse
    • Dutsch-Wicherek M., Tomaszewska R., Lazar A., Wicherek L. and Skladzien J. (2009). The association between RCAS1 expression in laryngeal and pharyngeal cancer and its healthy stroma with cancer relapse. BMC Cancer 9, 35-44.
    • (2009) BMC Cancer , vol.9 , pp. 35-44
    • Dutsch-Wicherek, M.1    Tomaszewska, R.2    Lazar, A.3    Wicherek, L.4    Skladzien, J.5
  • 20
    • 0035863097 scopus 로고    scopus 로고
    • RNA interference is mediated by 21-and 22-nucleotide RNAs
    • Elbashir S.M., Lendeckel W. and Tuschl T. (2001). RNA interference is mediated by 21-and 22-nucleotide RNAs. Genes Dev. 15, 188-200.
    • (2001) Genes Dev , vol.15 , pp. 188-200
    • Elbashir, S.M.1    Lendeckel, W.2    Tuschl, T.3
  • 21
    • 0033573049 scopus 로고    scopus 로고
    • Ectodomain shedding of TGF-a and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades
    • Fan H. and Derynck R. (1999). Ectodomain shedding of TGF-a and other transmembrane proteins is induced by receptor tyrosine kinase activation and MAP kinase signaling cascades. EMBO J. 18, 6962-6972.
    • (1999) EMBO J , vol.18 , pp. 6962-6972
    • Fan, H.1    Derynck, R.2
  • 22
    • 74549124210 scopus 로고    scopus 로고
    • Development of molecularly targeted therapies in hepatocellular carcinoma: Where do we go now?
    • Finn R.S. (2010). Development of molecularly targeted therapies in hepatocellular carcinoma: where do we go now? Clin. Cancer Res. 16, 390-397.
    • (2010) Clin. Cancer Res , vol.16 , pp. 390-397
    • Finn, R.S.1
  • 23
    • 0013297586 scopus 로고    scopus 로고
    • The expression of RCAS1 and tumor infiltrating lymphocytes in patients with T3 gastric carcinoma
    • Fukuda K., Tsujitani S., Maeta Y., Yamaguchi K., Ikeguchi M. and Kaibara N. (2002). The expression of RCAS1 and tumor infiltrating lymphocytes in patients with T3 gastric carcinoma. Gastric Cancer 5, 220-227.
    • (2002) Gastric Cancer , vol.5 , pp. 220-227
    • Fukuda, K.1    Tsujitani, S.2    Maeta, Y.3    Yamaguchi, K.4    Ikeguchi, M.5    Kaibara, N.6
  • 24
    • 16544371323 scopus 로고    scopus 로고
    • Expression of RCAS1 and its function in human squamous cell carcinoma of the oral cavity
    • Fukuda M., Tanaka A., Hamao A., Suzuki S., Kusama K. and Sakashita H. (2004). Expression of RCAS1 and its function in human squamous cell carcinoma of the oral cavity. Oncol. Rep. 12, 259-267.
    • (2004) Oncol. Rep , vol.12 , pp. 259-267
    • Fukuda, M.1    Tanaka, A.2    Hamao, A.3    Suzuki, S.4    Kusama, K.5    Sakashita, H.6
  • 25
    • 67650240271 scopus 로고    scopus 로고
    • Receptor-binding cancer antigen expressed on SiSo cells (RCAS1): A novel biomarker in the diagnosis and prognosis of human neoplasia
    • Giaginis C., Giagini A. and Theocharis S. (2009a). Receptor-binding cancer antigen expressed on SiSo cells (RCAS1): a novel biomarker in the diagnosis and prognosis of human neoplasia. Histol. Histopathol. 24, 761-776.
    • (2009) Histol Histopathol , vol.24 , pp. 761-776
    • Giaginis, C.1    Giagini, A.2    Theocharis, S.3
  • 26
    • 70349780065 scopus 로고    scopus 로고
    • Diagnostic and prognostic utility of serum receptor-binding cancer antigen expressed on SiSo cells (RCAS1) levels in colon cancer patients
    • Giaginis C., Margeli A., Kouraklis G., Zira A., Tsourouflis G. and Theocharis S. (2009b). Diagnostic and prognostic utility of serum receptor-binding cancer antigen expressed on SiSo cells (RCAS1) levels in colon cancer patients. Int. J. Biol. Markers 24, 70-76.
    • (2009) Int. J. Biol. Markers , vol.24 , pp. 70-76
    • Giaginis, C.1    Margeli, A.2    Kouraklis, G.3    Zira, A.4    Tsourouflis, G.5    Theocharis, S.6
  • 27
    • 0035575568 scopus 로고    scopus 로고
    • Personalized medicine: Revolutionizing drug discovery and patient care
    • Ginsburg G.S. and McCarthy J.J. (2001). Personalized medicine: revolutionizing drug discovery and patient care. Trends Biotechnol. 19, 491-496.
    • (2001) Trends Biotechnol , vol.19 , pp. 491-496
    • Ginsburg, G.S.1    McCarthy, J.J.2
  • 28
    • 30944452354 scopus 로고    scopus 로고
    • Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib
    • Hainsworth J.D., Sosman J.A., Spigel D.R., Edwards D.L., Baughman C. and Greco A. (2005). Treatment of metastatic renal cell carcinoma with a combination of bevacizumab and erlotinib. J. Clin. Oncol. 23, 7889-7896.
    • (2005) J. Clin. Oncol , vol.23 , pp. 7889-7896
    • Hainsworth, J.D.1    Sosman, J.A.2    Spigel, D.R.3    Edwards, D.L.4    Baughman, C.5    Greco, A.6
  • 29
    • 35148868377 scopus 로고    scopus 로고
    • Knockdown of RCAS1 expression by RNA interference recovers T cell growth and proliferation
    • Han Y., Qin W. and Huang G. (2007). Knockdown of RCAS1 expression by RNA interference recovers T cell growth and proliferation. Cancer Lett. 257, 182-190.
    • (2007) Cancer Lett , vol.257 , pp. 182-190
    • Han, Y.1    Qin, W.2    Huang, G.3
  • 31
    • 39049175197 scopus 로고    scopus 로고
    • Construction of recombinant GST-RCAS1 fusion gene and its expression in
    • Zhejiang Da Xue Xue Bao Yi Xue Ban
    • Hong X.J., Shen F.P. and Wang Q.Q. (2006). Construction of recombinant GST-RCAS1 fusion gene and its expression in E. coli. Zhejiang Da Xue Xue Bao Yi Xue Ban 35, 377-383.
    • (2006) E. Coli , vol.35 , pp. 377-383
    • Hong, X.J.1    Shen, F.P.2    Wang, Q.Q.3
  • 33
    • 33745684837 scopus 로고    scopus 로고
    • Targeting ADAMS and ERBBs in lung cancer
    • Hynes N.E. and Schlange T. (2006). Targeting ADAMS and ERBBs in lung cancer. Cancer Cell 10, 7-11.
    • (2006) Cancer Cell , vol.10 , pp. 7-11
    • Hynes, N.E.1    Schlange, T.2
  • 37
    • 0035878613 scopus 로고    scopus 로고
    • Expression of tumor-associated antigen RCAS1 correlates significantly with poor prognosis in nonsmall cell lung carcinoma
    • Izumi M., Nakanishi Y., Yoshino I., Nakashima M., Watanabe T. and Hara N. (2001). Expression of tumor-associated antigen RCAS1 correlates significantly with poor prognosis in nonsmall cell lung carcinoma. Cancer 92, 446-451.
    • (2001) Cancer , vol.92 , pp. 446-451
    • Izumi, M.1    Nakanishi, Y.2    Yoshino, I.3    Nakashima, M.4    Watanabe, T.5    Hara, N.6
  • 38
    • 17444373968 scopus 로고    scopus 로고
    • A metalloprotease-disintegrin, MDC9/meltrin-Á/ADAM9 and PKC‰ are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor
    • Izumi Y., Hirata M., Hasuwa H., Iwamoto R., Umata T., Miyado K., Tamai Y., Kurisaki T., Sehara-Fujisawa A., Ohno S. and Mekada E. (1998). A metalloprotease-disintegrin, MDC9/meltrin-Á/ADAM9 and PKC‰ are involved in TPA-induced ectodomain shedding of membrane-anchored heparin-binding EGF-like growth factor: EMBO J. 17, 7260-7272.
    • (1998) EMBO J , vol.17 , pp. 7260-7272
    • Izumi, Y.1    Hirata, M.2    Hasuwa, H.3    Iwamoto, R.4    Umata, T.5    Miyado, K.6    Tamai, Y.7    Kurisaki, T.8    Sehara-Fujisawa, A.9    Ohno, S.10    Mekada, E.11
  • 39
    • 0036924183 scopus 로고    scopus 로고
    • Personalized medicine
    • Jain K.K. (2002). Personalized medicine. Curr. Opin. Mol. Ther. 4, 548-558.
    • (2002) Curr. Opin. Mol. Ther , vol.4 , pp. 548-558
    • Jain, K.K.1
  • 42
    • 70449534597 scopus 로고    scopus 로고
    • EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments
    • Kataoka H. (2009). EGFR ligands and their signaling scissors, ADAMs, as new molecular targets for anticancer treatments. J. Dermatol. Sci. 56, 148-153.
    • (2009) J. Dermatol. Sci , vol.56 , pp. 148-153
    • Kataoka, H.1
  • 44
    • 24644520558 scopus 로고    scopus 로고
    • Tumor-stromal interactions in breast cancer: The role of stroma in tumorigenesis
    • Kim J.B., Stein R. and O'Hare M.J. (2005). Tumor-stromal interactions in breast cancer: the role of stroma in tumorigenesis. Tumor Biol. 26, 173-185.
    • (2005) Tumor Biol , vol.26 , pp. 173-185
    • Kim, J.B.1    Stein, R.2    O'Hare, M.J.3
  • 45
    • 34250703744 scopus 로고    scopus 로고
    • Vimentin and epithelial-mesenchymal transition in human breast cancer - observations in vitro and in vivo
    • Kokkinos M.I., Wafai R., Wong M.K., Newgreen D.F., Thompson E.W. and Waltham M. (2007). Vimentin and epithelial-mesenchymal transition in human breast cancer - observations in vitro and in vivo. Cells Tissues Organs 185, 191-203.
    • (2007) Cells Tissues Organs , vol.185 , pp. 191-203
    • Kokkinos, M.I.1    Wafai, R.2    Wong, M.K.3    Newgreen, D.F.4    Thompson, E.W.5    Waltham, M.6
  • 46
    • 67649304463 scopus 로고    scopus 로고
    • A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned
    • Koopman M., Venderbosch S., Nagtegaal I.D., van Krieken J.H. and Punt C.J. (2009). A review on the use of molecular markers of cytotoxic therapy for colorectal cancer, what have we learned? Eur. J. Cancer 45, 1935-1949.
    • (2009) Eur. J. Cancer , vol.45 , pp. 1935-1949
    • Koopman, M.1    Venderbosch, S.2    Nagtegaal, I.D.3    van Krieken, J.H.4    Punt, C.J.5
  • 47
    • 0035489755 scopus 로고    scopus 로고
    • Aberrant intracellular localization of RCAS1 is associated with tumor progression of gastric cancer
    • Kubokawa M., Nakashima M., Yao T., Ito K., Harada N., Nawata H. and Watanabe T. (2001). Aberrant intracellular localization of RCAS1 is associated with tumor progression of gastric cancer. Int. J Oncol. 19, 695-700.
    • (2001) Int. J Oncol , vol.19 , pp. 695-700
    • Kubokawa, M.1    Nakashima, M.2    Yao, T.3    Ito, K.4    Harada, N.5    Nawata, H.6    Watanabe, T.7
  • 48
    • 77951623830 scopus 로고    scopus 로고
    • Integrating high-throughput technologies in the quest for effective biomarkers for ovarian cancer
    • Kulasingam V., Pavlou M.P. and Diamandis E.P. (2010). Integrating high-throughput technologies in the quest for effective biomarkers for ovarian cancer. Nat. Rev. Cancer 10, 371-378.
    • (2010) Nat. Rev. Cancer , vol.10 , pp. 371-378
    • Kulasingam, V.1    Pavlou, M.P.2    Diamandis, E.P.3
  • 51
    • 0027236997 scopus 로고
    • Membrane-anchored growth factors
    • Massague J. and Pandiella A. (1993). Membrane-anchored growth factors. Annu. Rev. Biochem. 62, 515-541.
    • (1993) Annu. Rev. Biochem , vol.62 , pp. 515-541
    • Massague, J.1    Pandiella, A.2
  • 54
    • 72449170472 scopus 로고    scopus 로고
    • Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer
    • Mullenders J. and Bernards R. (2009). Loss-of-function genetic screens as a tool to improve the diagnosis and treatment of cancer. Oncogene 28, 4409-4420.
    • (2009) Oncogene , vol.28 , pp. 4409-4420
    • Mullenders, J.1    Bernards, R.2
  • 55
    • 74249092481 scopus 로고    scopus 로고
    • Biomarkers of angiogenesis and their role in the development of VEGF inhibitors
    • Murukesh N., Dive C. and Jayson G.C. (2010). Biomarkers of angiogenesis and their role in the development of VEGF inhibitors. Br. J. Cancer 102, 8-18.
    • (2010) Br. J. Cancer , vol.102 , pp. 8-18
    • Murukesh, N.1    Dive, C.2    Jayson, G.C.3
  • 56
    • 33845603580 scopus 로고    scopus 로고
    • Clinico-pathological significance of RCAS1 expression in gliomas: A potential mechanism of tumor immune escape
    • Nakabayashi H., Nakashima M., Hara M., Toyonaga S., Yamada S.M., Park K.C. and Shimizu K. (2007). Clinico-pathological significance of RCAS1 expression in gliomas: a potential mechanism of tumor immune escape. Cancer Lett. 246, 182-189.
    • (2007) Cancer Lett , vol.246 , pp. 182-189
    • Nakabayashi, H.1    Nakashima, M.2    Hara, M.3    Toyonaga, S.4    Yamada, S.M.5    Park, K.C.6    Shimizu, K.7
  • 59
    • 0032779988 scopus 로고    scopus 로고
    • Inhibition of cell growth and induction of apoptotic cell death by the human tumorassociated antigen RCAS1
    • Nakashima M., Sonoda K. and Watanabe T. (1999). Inhibition of cell growth and induction of apoptotic cell death by the human tumorassociated antigen RCAS1. Nat. Med. 5, 938-942.
    • (1999) Nat. Med , vol.5 , pp. 938-942
    • Nakashima, M.1    Sonoda, K.2    Watanabe, T.3
  • 60
    • 0031693206 scopus 로고    scopus 로고
    • Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signaling
    • Natoli G., Costanzo A., Guido F., Moretti F. and Lavrero M. (1998). Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signaling. Biochem. Pharmacol. 56, 915-920.
    • (1998) Biochem. Pharmacol , vol.56 , pp. 915-920
    • Natoli, G.1    Costanzo, A.2    Guido, F.3    Moretti, F.4    Lavrero, M.5
  • 62
    • 0036835612 scopus 로고    scopus 로고
    • Role of transforming growth factor beta in ovarian surface epithelium biology and ovarian cancer
    • Nilsson E.E. and Skinner M.K. (2002). Role of transforming growth factor beta in ovarian surface epithelium biology and ovarian cancer. Reprod. Biomed. Online 5, 254-258.
    • (2002) Reprod. Biomed. Online , vol.5 , pp. 254-258
    • Nilsson, E.E.1    Skinner, M.K.2
  • 65
    • 10744223788 scopus 로고    scopus 로고
    • Expression of tumor-associated membrane antigen, RCAS1, in human colorectal carcinomas and possible role in apoptosis of tumor-infiltrating lymphocytes
    • Okada K., Nakashima M., Komuta K., Hashimoto S., Okudaira S., Baba N., Hishikawa Y., Koji T., Kanematsu T. and Watanabe T. (2003). Expression of tumor-associated membrane antigen, RCAS1, in human colorectal carcinomas and possible role in apoptosis of tumor-infiltrating lymphocytes. Mod. Pathol. 16, 679-685.
    • (2003) Mod. Pathol , vol.16 , pp. 679-685
    • Okada, K.1    Nakashima, M.2    Komuta, K.3    Hashimoto, S.4    Okudaira, S.5    Baba, N.6    Hishikawa, Y.7    Koji, T.8    Kanematsu, T.9    Watanabe, T.10
  • 69
    • 33748319460 scopus 로고    scopus 로고
    • Significance of serum receptor-binding cancer antigen (RCAS1) in pancreatic cancer and benign pancreatobiliary diseases
    • Ozkan H., Akar T., Koklu S. and Coban S. (2006). Significance of serum receptor-binding cancer antigen (RCAS1) in pancreatic cancer and benign pancreatobiliary diseases. Pancreatology 6, 268-272.
    • (2006) Pancreatology , vol.6 , pp. 268-272
    • Ozkan, H.1    Akar, T.2    Koklu, S.3    Coban, S.4
  • 70
    • 71949092463 scopus 로고    scopus 로고
    • Nanomedicine based approaches for the delivery of siRNA in cancer
    • Ozpolat B., Sood A.K. and Lopez-Berestein G. (2010). Nanomedicine based approaches for the delivery of siRNA in cancer. J. Intern. Med. 267, 44-53.
    • (2010) J. Intern. Med , vol.267 , pp. 44-53
    • Ozpolat, B.1    Sood, A.K.2    Lopez-Berestein, G.3
  • 71
    • 65549115157 scopus 로고    scopus 로고
    • Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment
    • Phan J.H., Moffitt R.A., Stokes T.H., Liu J., Young A.N., Nie S. and Wang M.D. (2009). Convergence of biomarkers, bioinformatics and nanotechnology for individualized cancer treatment. Trends Biotechnol. 27, 350-358.
    • (2009) Trends Biotechnol , vol.27 , pp. 350-358
    • Phan, J.H.1    Moffitt, R.A.2    Stokes, T.H.3    Liu, J.4    Young, A.N.5    Nie, S.6    Wang, M.D.7
  • 72
    • 34249309574 scopus 로고    scopus 로고
    • Matrix metalloproteinaseinduced epithelial-mesenchymal transition: Tumor progression at Snail's pace
    • Przybylo J.A. and Radisky D.C. (2007). Matrix metalloproteinaseinduced epithelial-mesenchymal transition: tumor progression at Snail's pace. Int. J. Biochem. Cell Biol. 39, 1082-1088.
    • (2007) Int. J. Biochem. Cell Biol , vol.39 , pp. 1082-1088
    • Przybylo, J.A.1    Radisky, D.C.2
  • 74
    • 0033126105 scopus 로고    scopus 로고
    • A preliminary study of the immunohistochemistry detection of a novel tumour marker, 22-1-1 antigen, in gynaecological cancer specimens
    • Razvi K., Sonoda K., Lee Y.S., Tham K.F., Lim F.K. and Yong E.L. (1999). A preliminary study of the immunohistochemistry detection of a novel tumour marker, 22-1-1 antigen, in gynaecological cancer specimens. Ann. Acad. Med. Singapore 28, 392-394.
    • (1999) Ann. Acad. Med. Singapore , vol.28 , pp. 392-394
    • Razvi, K.1    Sonoda, K.2    Lee, Y.S.3    Tham, K.F.4    Lim, F.K.5    Yong, E.L.6
  • 76
    • 0025297086 scopus 로고
    • Overexpression of TGF-· in transgenic mice: Induction of epithelial hyperplasia, pancreatic metaplasia and carcinoma of the breast
    • Sandgren E.P., Luetteke N.C., Palmiter R.E., Brinster R.L. and Lee D.C. (1990). Overexpression of TGF-· in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia and carcinoma of the breast. Cell 61, 1121-1135.
    • (1990) Cell , vol.61 , pp. 1121-1135
    • Sandgren, E.P.1    Luetteke, N.C.2    Palmiter, R.E.3    Brinster, R.L.4    Lee, D.C.5
  • 77
    • 76249106934 scopus 로고    scopus 로고
    • Vascular endothelial growth factor receptor-1 in human cancer
    • Schwartz J.D., Rowinsky E.K., Youssoufian H., Pytowski B. and Wu Y. (2010). Vascular endothelial growth factor receptor-1 in human cancer. Cancer 116, 1027-1032.
    • (2010) Cancer , vol.116 , pp. 1027-1032
    • Schwartz, J.D.1    Rowinsky, E.K.2    Youssoufian, H.3    Pytowski, B.4    Wu, Y.5
  • 78
    • 0029015431 scopus 로고
    • Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination
    • Schweitzer R., Shaharabany M., Segar R. and Shilo B.Z. (1995). Secreted Spitz triggers the DER signaling pathway and is a limiting component in embryonic ventral ectoderm determination. Genes Dev. 9, 1518-1529.
    • (1995) Genes Dev , vol.9 , pp. 1518-1529
    • Schweitzer, R.1    Shaharabany, M.2    Segar, R.3    Shilo, B.Z.4
  • 79
    • 70349939382 scopus 로고    scopus 로고
    • Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer
    • Siena S., Sartore-Bianchi A., Nicolantonio F.D., Balfour J. and Bardelli A. (2009). Biomarkers predicting clinical outcome of epidermal growth factor receptor-targeted therapy in metastatic colorectal cancer. J. Natl. Cancer Inst. 101, 1308-1324.
    • (2009) J. Natl. Cancer Inst , vol.101 , pp. 1308-1324
    • Siena, S.1    Sartore-Bianchi, A.2    Nicolantonio, F.D.3    Balfour, J.4    Bardelli, A.5
  • 81
    • 0029966641 scopus 로고    scopus 로고
    • A novel tumor-associated antigen expressed in human uterine and ovarian carcinomas
    • Sonoda K., Nakashima M., Kaku T., Kamura T., Nakano H. and Watanabe T. (1996). A novel tumor-associated antigen expressed in human uterine and ovarian carcinomas. Cancer 77, 1501-1509.
    • (1996) Cancer , vol.77 , pp. 1501-1509
    • Sonoda, K.1    Nakashima, M.2    Kaku, T.3    Kamura, T.4    Nakano, H.5    Watanabe, T.6
  • 82
    • 0031747728 scopus 로고    scopus 로고
    • Tumor-associated antigen 22-1-1 expression in the uterine cervical squamous neoplasia
    • Sonoda K., Kaku T., Kamura T., Nakashima M., Watanabe T. and Nakano H. (1998). Tumor-associated antigen 22-1-1 expression in the uterine cervical squamous neoplasia. Clin. Cancer Res. 4, 1517-1520.
    • (1998) Clin. Cancer Res , vol.4 , pp. 1517-1520
    • Sonoda, K.1    Kaku, T.2    Kamura, T.3    Nakashima, M.4    Watanabe, T.5    Nakano, H.6
  • 83
    • 0033664872 scopus 로고    scopus 로고
    • The clinical significance of tumor-associated antigen RCAS1 expression in the normal, hyperplastic, and malignant uterine endometrium
    • Sonoda K., Kaku T., Hirakawa T., Kobayashi H., Amada S., Sakai K., Nakashima M., Watanabe T. and Nakano H. (2000). The clinical significance of tumor-associated antigen RCAS1 expression in the normal, hyperplastic, and malignant uterine endometrium. Gynecol. Oncol. 79 424-429.
    • (2000) Gynecol. Oncol , vol.79 , pp. 424-429
    • Sonoda, K.1    Kaku, T.2    Hirakawa, T.3    Kobayashi, H.4    Amada, S.5    Sakai, K.6    Nakashima, M.7    Watanabe, T.8    Nakano, H.9
  • 89
    • 35648957759 scopus 로고    scopus 로고
    • Biologic significance of receptorbinding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer
    • Sonoda K., Miyamoto S., Yamazaki A., Kobayashi H., Nakashima M., Mekada E. and Wake N. (2007b). Biologic significance of receptorbinding cancer antigen expressed on SiSo cells (RCAS1) as a pivotal regulator of tumor growth through angiogenesis in human uterine cancer. Cancer 110, 1979-1990.
    • (2007) Cancer , vol.110 , pp. 1979-1990
    • Sonoda, K.1    Miyamoto, S.2    Yamazaki, A.3    Kobayashi, H.4    Nakashima, M.5    Mekada, E.6    Wake, N.7
  • 90
    • 38449119294 scopus 로고    scopus 로고
    • The biological role of unique molecule RCAS1: A bioactive marker that induces connective tissue remodeling and lymphocyte apoptosis
    • Sonoda K., Miyamoto S., Nakashima M. and Wake N. (2008). The biological role of unique molecule RCAS1: a bioactive marker that induces connective tissue remodeling and lymphocyte apoptosis. Front. Biosci. 13, 1106-1116.
    • (2008) Front. Biosci , vol.13 , pp. 1106-1116
    • Sonoda, K.1    Miyamoto, S.2    Nakashima, M.3    Wake, N.4
  • 91
    • 69449099712 scopus 로고    scopus 로고
    • The level of RCAS1 expression is inversely correlated with the number of vimentin-positive stromal cells in epithelial ovarian cancer
    • Sonoda K., Miyamoto S., Kobayashi H., Ogawa S., Okugawa K., Taniguchi S. and Wake N. (2009). The level of RCAS1 expression is inversely correlated with the number of vimentin-positive stromal cells in epithelial ovarian cancer. Int. J. Gynecol. Cancer 19, 838-843.
    • (2009) Int. J. Gynecol. Cancer , vol.19 , pp. 838-843
    • Sonoda, K.1    Miyamoto, S.2    Kobayashi, H.3    Ogawa, S.4    Okugawa, K.5    Taniguchi, S.6    Wake, N.7
  • 92
    • 77953231977 scopus 로고    scopus 로고
    • Receptorbinding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding
    • Sonoda K., Miyamoto S., Nakashima M. and Wake N. (2010). Receptorbinding cancer antigen expressed on SiSo cells induces apoptosis via ectodomain shedding. Exp. Cell Res. 316, 1795-1803.
    • (2010) Exp. Cell Res , vol.316 , pp. 1795-1803
    • Sonoda, K.1    Miyamoto, S.2    Nakashima, M.3    Wake, N.4
  • 95
    • 0034815944 scopus 로고    scopus 로고
    • Molecular cloning and characterization of mouse EBAG9, homolog of a human cancer associated surface antigen: Expression and regulation by estrogen
    • Tsuchiya F., Ikeda K., Tsutsumi O., Hiroi H., Momoeda M., Taketani Y., Muramatsu M. and Inoue S. (2001). Molecular cloning and characterization of mouse EBAG9, homolog of a human cancer associated surface antigen: expression and regulation by estrogen. Biochem. Biophys. Res. Commun. 284, 2-10.
    • (2001) Biochem. Biophys. Res. Commun , vol.284 , pp. 2-10
    • Tsuchiya, F.1    Ikeda, K.2    Tsutsumi, O.3    Hiroi, H.4    Momoeda, M.5    Taketani, Y.6    Muramatsu, M.7    Inoue, S.8
  • 96
    • 33846847993 scopus 로고    scopus 로고
    • Prognostic significance of RCAS1 expression in relation to the infiltration of dendritic cells and lymphocytes in patients with esophageal carcinoma
    • Tsujitani S., Saito H., Oka S., Sakamoto T., Kanaji S., Tatebe S. and Ikeguchi M. (2007). Prognostic significance of RCAS1 expression in relation to the infiltration of dendritic cells and lymphocytes in patients with esophageal carcinoma. Dig. Dis. Sci. 52, 549-554.
    • (2007) Dig. Dis. Sci , vol.52 , pp. 549-554
    • Tsujitani, S.1    Saito, H.2    Oka, S.3    Sakamoto, T.4    Kanaji, S.5    Tatebe, S.6    Ikeguchi, M.7
  • 97
    • 0038350386 scopus 로고    scopus 로고
    • Targeted therapies for stage III nonsmall cell lung cancer: Integration in the combined modality setting
    • Vokes E.E. and Choy H. (2003). Targeted therapies for stage III nonsmall cell lung cancer: integration in the combined modality setting. Lung Cancer 41, S115-S121.
    • (2003) Lung Cancer , vol.41
    • Vokes, E.E.1    Choy, H.2
  • 100
    • 77951614830 scopus 로고    scopus 로고
    • Monoclonal antibodies: Versatile platforms for cancer immunotherapy
    • Weiner L.M., Surana R. and Wang S. (2010). Monoclonal antibodies: versatile platforms for cancer immunotherapy. Nat. Rev. Immunol. 10, 317-327.
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 317-327
    • Weiner, L.M.1    Surana, R.2    Wang, S.3
  • 101
    • 52049111595 scopus 로고    scopus 로고
    • Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor
    • Witters L., Scherle P., Friedman S., Friedman J., Caulder E., Newton R. and Lipton A. (2008). Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor. Cancer Res. 68, 7083-7089.
    • (2008) Cancer Res , vol.68 , pp. 7083-7089
    • Witters, L.1    Scherle, P.2    Friedman, S.3    Friedman, J.4    Caulder, E.5    Newton, R.6    Lipton, A.7
  • 103
    • 44349103191 scopus 로고    scopus 로고
    • Potential utility of the tumour marker RCAS1 for monitoring patients with invasive extramammary Paget's disease
    • Yoshida Y., Koga K., Watanabe T., Koga M., Takahashi A., Nakayama J. and Yamamoto O. (2008). Potential utility of the tumour marker RCAS1 for monitoring patients with invasive extramammary Paget's disease. Acta. Derm. Venereol. 88, 296-297.
    • (2008) Acta. Derm. Venereol , vol.88 , pp. 296-297
    • Yoshida, Y.1    Koga, K.2    Watanabe, T.3    Koga, M.4    Takahashi, A.5    Nakayama, J.6    Yamamoto, O.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.