Expression of a tumor-associated antigen, RCAS1, in canine mammary tumors

Journal of Veterinary Medical Science

Volumn 66, Issue 6, 2004, Pages 651-658

  Okamura, Yasuhiko ^a   Haraguchi, Tomoya ^a   Morimoto, Masahiro ^a   Okuda, Masaru ^a   Une, Satoshi ^a   Nakaichi, Munekazu ^a   Taura, Yasuho ^a  

^a YAMAGUCHI UNIVERSITY   (Japan)

Author keywords

Canine mammary tumor; DNA fragmentation; Immunohistochemistry; Receptor binding cancer antigen expressed on SiSo cells (RCAS1); Tumor infiltrating lymphocyte (TILs)

Indexed keywords

CD3 ANTIGEN; DIAGNOSTIC AGENT; EBAG9 PROTEIN, HUMAN; MESSENGER RNA; PRIMER DNA; TUMOR ANTIGEN;

ANIMAL; ANIMAL DISEASE; APOPTOSIS; ARTICLE; CELL CULTURE; CELL POLARITY; CHEMISTRY; DOG; EXPERIMENTAL NEOPLASM; FEMALE; FLUORESCENCE MICROSCOPY; GENE EXPRESSION REGULATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOSURVEILLANCE; NICK END LABELING; PATHOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE;

ANIMALS; ANTIGENS, CD3; ANTIGENS, NEOPLASM; APOPTOSIS; CELL POLARITY; DNA PRIMERS; DOGS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC SURVEILLANCE; IN SITU NICK-END LABELING; LYMPHOCYTES, TUMOR-INFILTRATING; MAMMARY NEOPLASMS, ANIMAL; MICROSCOPY, FLUORESCENCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 4844226593     PISSN: 09167250     EISSN: None     Source Type: Journal    
DOI: 10.1292/jvms.66.651     Document Type: Article

References (40)

1. Akashi, T., Oimomi, H., Nishiyama, K., Nakashima, M., Arita, Y., Sumii, T., Kimura, T., Ito, T., Nawata, H. and Watanabe, T. 2003. Expression and diagnostic evaluation of the human tumor-associated antigen RCAS1 in pancreatic cancer. Pancreas 26: 49-55.
2. Aoki, T., Inoue, S., Imamura, H., Fukushima, J., Takahashi, S., Urano, T., Hasegawa, K., Ogushi, T., Ouchi, Y. and Makuuchi, M. 2003. EBAG9/RCAS1 expression in hepatocellular carcinoma: correlation with tumour dedifferentiation and proliferation. Eur. J. Cancer 39: 1552-1561.
3. Barber, M. R. and Yang, T. J. 1999. Tumor infiltrating lymphocytes: CD8+ lymphocytes in canine transmissible venereal sarcomas at different stages of tumor growth. Anticancer Res. 19: 1137-1142.
4. Duffy, M. J. 2001. Biochemical markers in breast cancer: which ones are clinically useful? Clin. Biochem. 34: 347-352.
5. Enjoji, M., Nakashima, M., Nishi, H., Choi, I., Oimomi, H., Sugimoto, R., Kotoh, K., Taguchi, K., Nakamuta, M., Nawata, H. and Watanabe, T. 2002. The tumor-associated antigen, RCAS1, can be expressed in immune-mediated diseases as well as in carcinomas of biliary tract. J. Hepatol. 36: 786-792.
6. Fukuda, K., Tsujitani, S., Maeta, Y., Yamaguchi, K., Ikeguchi, M. and Kaibara, N. 2002. The expression of RCAS1 and tumor infiltrating lymphocytes in patients with T3 gastric carcinoma. Gastric Cancer 5: 220-227.
7. Grone, A., Weckmann, M. T., Capen, C. C. and Rosol, T. J. 1996. Canine glyceraldehyde-3-phosphate dehydrogenase complementary DNA: polymerase chain reaction amplification, cloning, partial sequence analysis, and use as loading control in ribonuclease protection assays. Am. J. Vet. Res. 57: 254-257.
8. Hamada, Y., Yamamura, M., Hioki, K., Yamamoto, M., Nagura, H. and Watanabe, K. 1985. Immunohistochemical study of carcinoembryonic antigen in patients with colorectal cancer. Correlation with plasma carcinoembryonic antigen levels. Cancer 55: 136-141.
9. Hiraoka, K., Hida, Y., Miyamoto, M., Oshikiri, T., Suzuoki, M., Nakakubo, Y., Shinohara, T., Itoh, T., Shichinohe, T., Kondo, S., Kasahara, N. and Katoh, H. 2002. High expression of tumor-associated antigen RCAS1 in pancreatic ductal adenocarcinoma is an unfavorable prognostic marker. Int. J. Cancer 99: 418-423.
10. Hsiao, Y. W., Liao, K. W., Hung, S. W. and Chu R.M. 2002. Effect of tumor infiltrating lymphocytes on the expression of MHC molecules in canine transmissible venereal tumor cells. Vet. Immunol. Immunopathol. 87: 19-27.
11. Ichihara, T., Nagura, H., Nakao, A., Sakamoto, J., Watanabe, T. and Takagi, H. 1988. Immunohistochemical localization of CA 19-9 and CEA in pancreatic carcinoma and associated diseases. Cancer 61: 324-333.
12. Ikeda, K., Sato, M., Tsutsumi, O., Tsuchiya, F., Tsuneizumi, M., Emi, M., Imoto, I., Inazawa, J., Muramatsu, M. and Inoue, S. 2000. Promoter analysis and chromosomal mapping of human EBAG9 gene. Biochem. Biophys. Res. Commun. 273: 654-660.
13. Iwasaki, T., Nakashima, M., Watanabe, T., Yamamoto, S., Inoue, Y., Yamanaka, H., Matsumura, A., Iuchi, K., Mori, T. and Oada, M. 2000. Expression and prognostic significance in lung cancer of human tumor-associated antigen RCAS1. Int. J. Cancer 89: 488-493.
14. Izumi, M., Nakanishi, Y., Yoshino, I., Nakashima, M., Watanabe, T. and Hara, N. 2001. Expression of tumor-associated antigen RCAS1 correlates significantly with poor prognosis in nonsmall cell lung carcinoma. Cancer 92: 446-451.
15. Kaku, T., Sonoda, K., Kamura, T., Hirakawa, T., Sakai, K., Amada, S., Ogawa, S., Kobayashi, H., Nakashima, M., Watanabe, T. and Nakano, H. 1999. The prognostic significance of tumor-associated antigen 22-1-1 expression in adenocarcinoma of the uterine cervix. Clin. Cancer. Res. 5: 1449-1453.
16. Kubokawa, M., Nakashima, M., Yao, T., Ito, K. I., Harada, N., Nawata, H. and Watanabe, T. 2001. Aberrant intracellular localization of RCAS1 is associated with tumor progression of gastric cancer. Int. J. Oncol. 19: 695-700.
17. Misdorp, W., Else, W., Hellmen, E. and Lipscomb, T. P. 1999. Histological classification of the mammary tumors of the dog and the cat. pp. 1-59. In: World Health Organization International Histological Classification of Tumors of Domestic Animals, 2nd series, vol. 7, Armed Forces Institute of Pathology, Washington.
18. Morrison, W. B. 1998. Canine and feline mammary tumors, pp. 591-598 In: Cancer in Dogs and Cats (Lippincott, W. ed.), Lippincott, Williams & Wilkins, Philadelphia.
19. Nakakubo, Y., Hida, Y., Miyamoto, M., Hashida, H., Oshikiri, T., Kato, K., Suzuoki, M., Hiraoka, K., Ito, T., Morikawa, T., Okushiba, S., Kondo, S. and Katoh, H. 2002. The prognostic significance of RCAS1 expression in squamous cell carcinoma of the oesophagus. Cancer Lett. 177: 101-105.
20. Nakashima, M., Sonoda, K. and Watanabe, T. 1999. Inhibition of cell growth and induction of apoptotic cell death by the human tumor-associated antigen RCAS1. Nat. Med. 5: 938-942.
21. Noguchi, K., Enjoji, M., Nakamuta, M., Nakashima, M., Nishi, H., Choi, I., Taguchi, K., Kotoh, K., Shimada, M., Sugimachi, K., Tsuneyoshi, M., Nawata, H. and Watanabe, T. 2001. Expression of a tumor-associated antigen RCAS1 in hepatocellular carcinoma. Cancer Lett. 168: 197-202.
22. Oizumi, S., Yamazaki, K., Nakashima, M., Watanabe, T., Hommura, F., Ogura, S., Nishimura, M. and Dosaka-Akita, H. 2002. RCAS1 expression: a potential prognostic marker for adenocarcinomas of the lung. Oncology 62: 333-339.
23. Okamura, Y., Ma, Z., Khatlani, T. S., Okuda, M., Une, S., Nakaichi, M. and Taura, Y. 2003. Molecular Cloning of Canine RCAS1 cDNA. J. Vet. Med. Sci. 65: 913-915.
24. Owens, L. N. 1980. Classification of Tumors in Domestic Animals, 1st ed., World Health Organization, Geneva.
25. Perez, J., Day, M. J. and Mozos, E. 1998. Immunohistochemical study of the local inflammatory infiltrate in spontaneous canine transmissible venereal tumour at different stages of growth. Vet. Immunol. Immunopathol. 64: 133-147.
26. Rousseau, J., Tetu, B., Caron, D., Malenfant, P., Cattaruzzi, P., Audette, M., Doillon, C., Tremblay, J. P. and Guerette, B. 2002. RCAS1 is associated with ductal breast cancer progression. Biochem. Biophys. Res. Commun. 293: 1544-1549.
27. Rutteman, G. R., Withrow, S. J. and MacEwen, E. G. 2001. Tumor of the mammary gland, pp. 455-477. In: Small Animal Clinical Ooncology (Withrow, S. J. and MacEwen, E. G. eds.), WB Saunders Co., Philadelphia.
28. Sonoda, K., Nakashima, M., Kaku, T., Kamura, T., Nakano, H. and Watanabe, T. 1996. A novel tumor-associated antigen expressed in human uterine and ovarian carcinomas. Cancer 77: 1501-1509.
29. Sonoda, K., Kaku, T., Kamura, T., Nakashima, M., Watanabe, T. and Nakano, H. 1998. Tumor-associated antigen 22-1-1 expression in the uterine cervical squamous neoplasias. Clin. Cancer Res. 4: 1517-1520.
30. Sonoda, K., Kaku, T., Hirakawa, T., Kobayashi, H., Amada, S., Sakai, K., Nakashima, M., Watanabe, T. and Nakano, H. 2000. The clinical significance of tumor-associated antigen RCAS1 expression in the normal, hyperplastic, and malignant uterine endometrium. Gynecol. Oncol. 79: 424-429.
31. Sonoda, K., Miyamoto, S., Hirakawa, T., Kaku, T., Nakashima, M., Watanabe, T., Akazawa, K., Fujita, T. and Nakano, H. 2003. Association between RCAS1 expression and clinical outcome in uterine endometrial cancer. Br. J. Cancer 89: 546-551.
32. Suzuki, T., Inoue, S., Kawabata, W., Akahira, J., Moriya, T., Tsuchiya, F., Ogawa, S., Muramatsu, M. and Sasano, H. 2001. EBAG9/RCAS1 in human breast carcinoma: a possible factor in endocrine-immune interactions. Br. J. Cancer 85: 1731-1737.
33. Tada, K., Oka, M., Tangoku, A., Hayashi, H., Oga, A. and Sasaki, K. Gains of 8q23-qter and 20q and loss of 11q22-qter in esophageal squamous cell carcinoma associated with lymph node metastasis. Cancer 88: 268-273.
34. Tsuchiya, F., Ikeda, K., Tsutsumi, O., Hiroi, H., Momoeda, M., Taketani, Y., Muramatsu, M. and Inoue, S. 2001. Molecular cloning and characterization of mouse EBAG9, homolog of a human cancer associated surface antigen: expression and regulation by estrogen. Biochem. Biophys. Res. Commun. 284: 2-10.
35. Tsuneizumi, M., Emi, M., Nagai, H., Harada, H., Sakamoto, G., Kasumi, F., Inoue, S., Kazui, T. and Nakamura, Y. 2001. Overrepresentation of the EBAG9 gene at 8q23 associated with early-stage breast cancers. Clin. Cancer Res. 7: 3526-3532.
36. Tsuneizumi, M., Nagai, H., Harada, H., Kazui, T. and Emi, M. 2002. A highly polymorphic CA repeat marker at the EBAG9/RCAS1 locus on 8q23 that detected frequent multiplication in breast cancer. Ann. Hum. Biol. 29: 457-460.
37. Underwood, J. C. E. 1974. Lymphoreticular infiltration in human tumours: prognostic and biological implications. Br. J. Cancer 30: 538-548.
38. Walch, A. K., Zitzelsberger, H. F., Bruch, J., Keller, G., Angermeier, D., Aubele, M. M., Mueller, J., Stein, H., Braselmann, H., Siewert, J. R., Hofler, H. and Werner, M. 2000. Chromosomal imbalances in Barrett's adenocarcinoma and the metaplasia-dysplasia-carcinoma sequence. Am. J. Pathol. 156: 555-566.
39. Watanabe, T., Inoue, S., Hiroi, H., Orimo, A., Kawashima, H. and Muramatsu, M. 1998. Isolation of estrogen-responsive genes with a CpG island library. Mol. Cell Biol. 18: 442-449.
40. Yang, Z. Q., Yoshida, M. A., Fukuda, Y., Kurihara, N., Nakamura, Y. and Inazawa, J. 2000. Molecular cytogenetic analysis of 17 renal cancer cell lines: increased copy number at 5q31-33 in cell lines from nonpapillary carcinomas. Jpn. J. Cancer Res. 91: 156-163.