-
1
-
-
37549059612
-
Regulation of iron acquisition and storage: Consequences for iron-linked disorders
-
10.1038/nrm2295 17987043
-
Regulation of iron acquisition and storage: consequences for iron-linked disorders. De Domenico I, McVey Ward D, Kaplan J, Nat Rev Mol Cell Biol 2008 9 72 81 10.1038/nrm2295 17987043
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 72-81
-
-
De Domenico, I.1
McVey Ward, D.2
Kaplan, J.3
-
2
-
-
41949115757
-
Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin
-
DOI 10.1152/ajpcell.00563.2007
-
Selective binding of RGMc/hemojuvelin, a key protein in systemic iron metabolism, to BMP-2 and neogenin. Kune-Hashimoto R, Kuninger D, Nili M, Rotwein P, Amer J Physiol 2008 294 994 C1003 10.1152/ajpcell.00563.2007 (Pubitemid 351507912)
-
(2008)
American Journal of Physiology - Cell Physiology
, vol.294
, Issue.4
-
-
Kuns-Hashimoto, R.1
Kuninger, D.2
Nili, M.3
Rotwein, P.4
-
3
-
-
56449096622
-
The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin
-
10.1016/j.cmet.2008.09.012 18976966
-
The serine protease matriptase-2 (TMPRSS6) inhibits hepcidin activation by cleaving membrane hemojuvelin. Silvestri L, Pagani A, Nai A, De Domenico I, Kaplan J, Camaschella C, Cell Metab 2008 8 502 511 10.1016/j.cmet.2008.09.012 18976966
-
(2008)
Cell Metab
, vol.8
, pp. 502-511
-
-
Silvestri, L.1
Pagani, A.2
Nai, A.3
De Domenico, I.4
Kaplan, J.5
Camaschella, C.6
-
4
-
-
63449103712
-
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
-
10.1038/ng.335
-
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Andriopoulos B Jr, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL, Na Genet 2009 41 482 487 10.1038/ng.335
-
(2009)
Na Genet
, vol.41
, pp. 482-487
-
-
Andriopoulos Jr., B.1
Corradini, E.2
Xia, Y.3
Faasse, S.A.4
Chen, S.5
Grgurevic, L.6
Knutson, M.D.7
Pietrangelo, A.8
Vukicevic, S.9
Lin, H.Y.10
Babitt, J.L.11
-
5
-
-
69249118614
-
Hemojuvelin/neogenin interaction is required for bone morphogenic protein-4-induced hepcidin expression
-
10.1074/jbc.M109.027318 19564337
-
Hemojuvelin/neogenin interaction is required for bone morphogenic protein-4-induced hepcidin expression. Zhang AS, Yang F, Wang J, Tsukamoto H, Enns CA, J Biol Chem 2009 284 22580 22589 10.1074/jbc.M109.027318 19564337
-
(2009)
J Biol Chem
, vol.284
, pp. 22580-22589
-
-
Zhang, A.S.1
Yang, F.2
Wang, J.3
Tsukamoto, H.4
Enns, C.A.5
-
6
-
-
27144459908
-
Competitive regulation of hepcidin mRNAby soluble and cell-associated hemojuvelin
-
DOI 10.1182/blood-2005-05-1845
-
Competitive regulation of hepcidin mRNA by soluble and cell-associated hemojuvelin. Lin L, Goldberg YP, Ganz T, Blood 2005 106 2884 2889 10.1182/blood-2005-05-1845 15998830 (Pubitemid 41510769)
-
(2005)
Blood
, vol.106
, Issue.8
, pp. 2884-2889
-
-
Lin, L.1
Goldberg, Y.P.2
Ganz, T.3
-
7
-
-
33748797945
-
Complex biosynthesis of the muscle-enriched iron regulator RGMc
-
DOI 10.1242/jcs.03074
-
Complex biosynthesis of the muscle-enriched iron regulator RGMc. Kuninger D, Kune-Hashimoto R, Kuzmickas R, Rotwein P, J Cell Sci 2006 119 3273 3283 10.1242/jcs.03074 16868025 (Pubitemid 44405213)
-
(2006)
Journal of Cell Science
, vol.119
, Issue.16
, pp. 3273-3283
-
-
Kuninger, D.1
Kuns-Hashimoto, R.2
Kuzmickas, R.3
Rotwein, P.4
-
8
-
-
42249103992
-
Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin
-
DOI 10.1186/1471-2091-9-9
-
Pro-protein convertases control the maturation and processing of the iron-regulatory protein, RGMc/hemojuvelin. Kuninger D, Kune-Hashimoto R, Nili M, Rotwein P, BMC Biochem 2008 9 9 10.1186/1471-2091-9-9 18384687 (Pubitemid 351551355)
-
(2008)
BMC Biochemistry
, vol.9
, Issue.1
, pp. 9
-
-
Kuninger, D.1
Kuns-Hashimoto, R.2
Nili, M.3
Rotwein, P.4
-
9
-
-
36649027658
-
Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site
-
DOI 10.1016/j.bcmd.2007.06.023, PII S1079979607001428
-
Soluble hemojuvelin is released by proprotein convertase-mediated cleavage at a conserved polybasic RNRR site. Lin L, Nemeth E, Goodnough JB, Thapa DR, Gabayan V, Ganz T, Blood Cells Mol Dis 2008 40 122 131 10.1016/j.bcmd.2007.06.023 17869549 (Pubitemid 350193320)
-
(2008)
Blood Cells, Molecules, and Diseases
, vol.40
, Issue.1
, pp. 122-131
-
-
Lin, L.1
Nemeth, E.2
Goodnough, J.B.3
Thapa, D.R.4
Gabayan, V.5
Ganz, T.6
-
10
-
-
38349194098
-
Furin-mediated release of soluble hemojuvelin: A new link between hypoxia and iron homeostasis
-
10.1182/blood-2007-07-100677 17938254
-
Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis. Silvestri L, Pagani A, Camaschella C, Blood 2008 111 924 931 10.1182/blood-2007-07-100677 17938254
-
(2008)
Blood
, vol.111
, pp. 924-931
-
-
Silvestri, L.1
Pagani, A.2
Camaschella, C.3
-
11
-
-
47749119908
-
Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane
-
10.1074/jbc.M710527200 18445598
-
Neogenin-mediated hemojuvelin shedding occurs after hemojuvelin traffics to the plasma membrane. Zhang AS, Yang F, Meyer K, Hernandez C, Chapman-Arvedson T, Bjorkman PJ, Enns C A, J Biol Chem 2008 283 17494 17502 10.1074/jbc. M710527200 18445598
-
(2008)
J Biol Chem
, vol.283
, pp. 17494-17502
-
-
Zhang, A.S.1
Yang, F.2
Meyer, K.3
Hernandez, C.4
Chapman-Arvedson, T.5
Bjorkman, P.J.6
Enns, C.A.7
-
12
-
-
77952300272
-
Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin
-
19249912
-
Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin. Krijt J, Fujikura Y, Sefc L, Vokurka M, Hlobenova T, Necas E, Physiol Res 2010 59 53 59 19249912
-
(2010)
Physiol Res
, vol.59
, pp. 53-59
-
-
Krijt, J.1
Fujikura, Y.2
Sefc, L.3
Vokurka, M.4
Hlobenova, T.5
Necas, E.6
-
13
-
-
61849129278
-
Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells
-
10.1182/blood-2008-08-174565 19029439
-
Processing of hemojuvelin requires retrograde trafficking to the Golgi in HepG2 cells. Maxson J, E Enns CA, Zhang A S, Blood 2009 113 1786 1793 10.1182/blood-2008-08-174565 19029439
-
(2009)
Blood
, vol.113
, pp. 1786-1793
-
-
Maxson, J.1
Enns C A, E.2
Zhang, A.S.3
-
14
-
-
18544379947
-
RGM is a repulsive guidance molecule for retinal axoms
-
10.1038/nature01041 12353034
-
RGM is a repulsive guidance molecule for retinal axoms. Monnier PP, Sierra A, Macchi P, Deitinghoff L, Andersen JS, Mann M, Flad M, Homberger MR, Stahl B, Bonhoeffer F, Mueller B K, Nature 2002 419 392 395 10.1038/nature01041 12353034
-
(2002)
Nature
, vol.419
, pp. 392-395
-
-
Monnier, P.P.1
Sierra, A.2
MacChi, P.3
Deitinghoff, L.4
Andersen, J.S.5
Mann, M.6
Flad, M.7
Homberger, M.R.8
Stahl, B.9
Bonhoeffer, F.10
Mueller, B.K.11
-
15
-
-
11144245556
-
Repulsive guidance molecule/neogenin: A novel ligand-receptor system playing multiple roles in neural development
-
DOI 10.1111/j.1440-169x.2004.00768.x
-
Repulsive guidance molecule/neogenin: a novel ligand-receptor system playing multiple roles in neural development. Matsunaga E, Chédotal A, Dev Growth Differ 2004 46 481 486 10.1111/j.1440-169x.2004.00768.x 15610137 (Pubitemid 40052753)
-
(2004)
Development Growth and Differentiation
, vol.46
, Issue.6
, pp. 481-486
-
-
Matsunaga, E.1
Chedotal, A.2
-
16
-
-
34547759860
-
Role of RGM coreceptors in bone morphogenetic protein signaling
-
DOI 10.1186/1750-2187-2-4
-
Role of RGM coreceptors in bone morphogenetic protein signaling. Halbrooks PJ, Ding R, Wozney JM, Bain G, J Mol Signal 2007 2 4 10.1186/1750-2187-2-4 17615080 (Pubitemid 47226250)
-
(2007)
Journal of Molecular Signaling
, vol.2
, pp. 4
-
-
Halbrooks, P.J.1
Ding, R.2
Wozney, J.M.3
Bain, G.4
-
17
-
-
0344234409
-
Isolation and expression pattern of three mouse homologues of chick Rgm
-
DOI 10.1016/S1567-133X(03)00144-3, PII S1567133X03001443
-
Isolation and expression pattern of three mouse homologues of chick Rgm. Schmidtmer J, Engelkamp D, Gene Expr Patterns 2004 4 105 110 10.1016/S1567-133X(03)00144-3 14678836 (Pubitemid 37498301)
-
(2004)
Gene Expression Patterns
, vol.4
, Issue.1
, pp. 105-110
-
-
Schmidtmer, J.1
Engelkamp, D.2
-
18
-
-
1642395635
-
Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development
-
DOI 10.1016/j.modgep.2003.11.008, PII S1567133X03002230
-
Expression pattern of the repulsive guidance molecules RGM A, B and C during mouse development. Oldekamp J, Kramer N, Alvarez-Bolado G, Skutella T, Gene Expr Patterns 2004 4 283 288 10.1016/j.modgep.2003.11.008 15053976 (Pubitemid 38397005)
-
(2004)
Gene Expression Patterns
, vol.4
, Issue.3
, pp. 283-288
-
-
Oldekamp, J.1
Kramer, N.2
Alvarez-Bolado, G.3
Skutella, T.4
-
19
-
-
0742322861
-
Repulsive Guidance Molecule (RGM) Gene Function Is Required for Neural Tube Closure but Not Retinal Topography in the Mouse Visual System
-
DOI 10.1523/JNEUROSCI.4610-03.2004
-
Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. Niederkofler V, Salie R, Sigrist M, Arber S, J Neurosci 2004 24 808 818 10.1523/JNEUROSCI. 4610-03.2004 14749425 (Pubitemid 38146591)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.4
, pp. 808-818
-
-
Niederkofler, V.1
Salie, R.2
Sigrist, M.3
Arber, S.4
-
20
-
-
26644471267
-
Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells
-
DOI 10.1074/jbc.M506207200
-
Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells. Zhang AS, West AP Jr, Wyman AE, Bjorkman PJ, Enns C A, J Biol Chem 2005 280 33885 33894 10.1074/jbc.M506207200 16103117 (Pubitemid 41443108)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.40
, pp. 33885-33894
-
-
Zhang, A.-S.1
West Jr., A.P.2
Wyman, A.E.3
Bjorkman, P.J.4
Enns, C.A.5
-
21
-
-
78649898652
-
Immunoassay for human serum hemojuvelin
-
10.3324/haematol.2010.022129 20713458
-
Immunoassay for human serum hemojuvelin. Brasse-Lagnel C, Poli M, Lesueur C, Grandchamp B, Lavoinne A, Beaumont C, Bekin S, Haematologica 2010 95 2031 2037 10.3324/haematol.2010.022129 20713458
-
(2010)
Haematologica
, vol.95
, pp. 2031-2037
-
-
Brasse-Lagnel, C.1
Poli, M.2
Lesueur, C.3
Grandchamp, B.4
Lavoinne, A.5
Beaumont, C.6
Bekin, S.7
-
22
-
-
78449299628
-
Conserved proximal promoter elements control repulsive guidance molecule c/hemojuvelin gene transcription in skeletal muscle
-
10.1016/j.ygeno.2010.09.001 20858542
-
Conserved proximal promoter elements control repulsive guidance molecule c/hemojuvelin gene transcription in skeletal muscle. Severyn CJ, Rotwein P, Genomics 2010 96 342 351 10.1016/j.ygeno.2010.09.001 20858542
-
(2010)
Genomics
, vol.96
, pp. 342-351
-
-
Severyn, C.J.1
Rotwein, P.2
-
23
-
-
33748195979
-
Glycosylation in cellular mechanisms of health and disease
-
DOI 10.1016/j.cell.2006.08.019, PII S0092867406010865
-
Glycosylation in Cellular Mechanisms of Health and Disease. Ohtsubo K, Martin JD, Cell 2006 126 855 867 10.1016/j.cell.2006.08.019 16959566 (Pubitemid 44310784)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 855-867
-
-
Ohtsubo, K.1
Marth, J.D.2
-
24
-
-
0035937505
-
Intracellular functions of N-linked glycans
-
DOI 10.1126/science.291.5512.2364
-
Intracellular functions of N-linked glycans. Helenius A, Aebi M, Science 2001 291 2364 2369 10.1126/science.291.5512.2364 11269317 (Pubitemid 32231791)
-
(2001)
Science
, vol.291
, Issue.5512
, pp. 2364-2369
-
-
Helenius, A.1
Aebi, M.2
-
25
-
-
3943059566
-
Roles of N-linked glycans in the endoplasmic reticulum
-
DOI 10.1146/annurev.biochem.73.011303.073752
-
Roles of N-linked glycans in the endoplasmic reticulum. Helenius A, Aebi M, Annu Rev Biochem 2004 73 1019 1049 10.1146/annurev.biochem.73.011303.073752 15189166 (Pubitemid 39050393)
-
(2004)
Annual Review of Biochemistry
, vol.73
, pp. 1019-1049
-
-
Helenius, A.1
Aebi, M.2
-
26
-
-
33745272509
-
Cell signaling, the essential role of O-GlcNAc!
-
DOI 10.1016/j.bbalip.2006.04.007, PII S138819810600120X
-
Cell signaling, the essential role of O-GlcNAc! Zachara NE, Hart GW, Biochim Biophys Acta 2006 1761 599 617 16781888 (Pubitemid 43928866)
-
(2006)
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids
, vol.1761
, Issue.5-6
, pp. 599-617
-
-
Zachara, N.E.1
Hart, G.W.2
-
27
-
-
23644444316
-
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
-
DOI 10.1172/JCI25683
-
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. Niederkofler V, Salie R, Arber S, J Clin Invest 2005 115 2180 2186 10.1172/JCI25683 16075058 (Pubitemid 41134159)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.8
, pp. 2180-2186
-
-
Niederkofler, V.1
Salie, R.2
Arber, S.3
-
28
-
-
46849102138
-
The glycosylphosphatidylinositol anchor: A complex membrane-anchoring structure for proteins
-
DOI 10.1021/bi8006324
-
The Glycosylphosphatidylinositol anchor: A complex membrane-anchoring structure for proteins. Paulick MG, Bertozzi C R, Biochemistry 2008 47 6991 7000 10.1021/bi8006324 18557633 (Pubitemid 351956348)
-
(2008)
Biochemistry
, vol.47
, Issue.27
, pp. 6991-7000
-
-
Paulick, M.G.1
Bertozzi, C.R.2
-
29
-
-
79960848290
-
Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6)
-
Liver hemojuvelin protein levels in mice deficient in matriptase-2 (Tmprss6). Krijt J, Fujikura Y, Ramsay AJ, Velasco G, Necas E, Blood Cells Mol Dis 2011
-
(2011)
Blood Cells Mol Dis
-
-
Krijt, J.1
Fujikura, Y.2
Ramsay, A.J.3
Velasco, G.4
Necas, E.5
-
30
-
-
34248371666
-
Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis
-
DOI 10.1182/blood-2006-08-041004
-
Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. Silvestri L, Pagani A, Fazi C, Gerardi G, Levi S, Arosio P, Camaschella C, Blood 2007 109 4503 4510 10.1182/blood-2006-08-041004 17264300 (Pubitemid 46743421)
-
(2007)
Blood
, vol.109
, Issue.10
, pp. 4503-4510
-
-
Silvestri, L.1
Pagani, A.2
Fazi, C.3
Gerardi, G.4
Levi, S.5
Arosio, P.6
Camaschella, C.7
-
32
-
-
70249087694
-
Molecular biology, genetics and biochemistry of the repulsive guidance molecule family
-
10.1042/BJ20090978 19698085
-
Molecular biology, genetics and biochemistry of the repulsive guidance molecule family. Severyn CJ, Shinde U, Rotwein P, Biochem J 2009 422 393 403 10.1042/BJ20090978 19698085
-
(2009)
Biochem J
, vol.422
, pp. 393-403
-
-
Severyn, C.J.1
Shinde, U.2
Rotwein, P.3
-
33
-
-
77952747961
-
The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo
-
10.1074/jbc.M110.109488 20363739
-
The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo. Zhang AS, Gao J, Koeberl DD, Enns CA, J Biol Chem 2010 285 16416 16423 10.1074/jbc.M110.109488 20363739
-
(2010)
J Biol Chem
, vol.285
, pp. 16416-16423
-
-
Zhang, A.S.1
Gao, J.2
Koeberl, D.D.3
Enns, C.A.4
|