메뉴 건너뛰기




Volumn 6, Issue 9, 2011, Pages

Partial inhibition of estrogen-induced mammary carcinogenesis in rats by tamoxifen: Balance between oxidant stress and estrogen responsiveness

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; 8 ISOPROSTANE; CATALASE; ESTRADIOL; ESTROGEN RECEPTOR; GLUTATHIONE PEROXIDASE; PROGESTERONE RECEPTOR; SUPEROXIDE DISMUTASE; TAMOXIFEN; 8 ISOPROSTAGLANDIN E2; 8-HYDROXY-2'-DEOXYGUANOSINE; 8-ISOPROSTAGLANDIN E2; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; DEOXYGUANOSINE; DRUG DERIVATIVE; ESTROGEN; ISOPROSTANE DERIVATIVE; PROSTAGLANDIN E2;

EID: 80053136223     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025125     Document Type: Article
Times cited : (33)

References (68)
  • 2
    • 33746847720 scopus 로고    scopus 로고
    • Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention
    • Cavalieri E, Chakravarti D, Guttenplan J, Hart E, Ingle J, et al. (2006) Catechol estrogen quinones as initiators of breast and other human cancers: implications for biomarkers of susceptibility and cancer prevention. Biochim Biophys Acta 1766: 63-78.
    • (2006) Biochim Biophys Acta , vol.1766 , pp. 63-78
    • Cavalieri, E.1    Chakravarti, D.2    Guttenplan, J.3    Hart, E.4    Ingle, J.5
  • 3
    • 84860421689 scopus 로고    scopus 로고
    • IARC monographs on the evaluation of carcinogenic risks to humans: hormonal contraception and postmenopausal hormone therapy
    • IARC
    • IARC (1999) IARC monographs on the evaluation of carcinogenic risks to humans: hormonal contraception and postmenopausal hormone therapy. International Agency for Research on Cancer, Lyon 72: 474-530.
    • (1999) International Agency for Research on Cancer, Lyon , vol.72 , pp. 474-530
  • 4
    • 33847795224 scopus 로고    scopus 로고
    • Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers: keynote lecture
    • Cavalieri E, Rogan E, (2006) Catechol quinones of estrogens in the initiation of breast, prostate, and other human cancers: keynote lecture. Ann N Y Acad Sci 1089: 286-301.
    • (2006) Ann N Y Acad Sci , vol.1089 , pp. 286-301
    • Cavalieri, E.1    Rogan, E.2
  • 5
    • 0035945656 scopus 로고    scopus 로고
    • Estrogen and the risk of breast cancer
    • Clemons M, Goss P, (2001) Estrogen and the risk of breast cancer. N Engl J Med 344: 276-285.
    • (2001) N Engl J Med , vol.344 , pp. 276-285
    • Clemons, M.1    Goss, P.2
  • 6
    • 0025313058 scopus 로고
    • Free radical generation by redox cycling of estrogens
    • Liehr JG, Roy D, (1990) Free radical generation by redox cycling of estrogens. Free Radic Biol Med 8: 415-423.
    • (1990) Free Radic Biol Med , vol.8 , pp. 415-423
    • Liehr, J.G.1    Roy, D.2
  • 7
    • 51549099366 scopus 로고    scopus 로고
    • Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure
    • Mense SM, Remotti F, Bhan A, Singh B, El-Tamer M, et al. (2008) Estrogen-induced breast cancer: alterations in breast morphology and oxidative stress as a function of estrogen exposure. Toxicol Appl Pharmacol 232: 78-85.
    • (2008) Toxicol Appl Pharmacol , vol.232 , pp. 78-85
    • Mense, S.M.1    Remotti, F.2    Bhan, A.3    Singh, B.4    El-Tamer, M.5
  • 8
    • 67650159397 scopus 로고    scopus 로고
    • Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats
    • Mense SM, Singh B, Remotti F, Liu X, Bhat HK, (2009) Vitamin C and alpha-naphthoflavone prevent estrogen-induced mammary tumors and decrease oxidative stress in female ACI rats. Carcinogenesis 30: 1202-1208.
    • (2009) Carcinogenesis , vol.30 , pp. 1202-1208
    • Mense, S.M.1    Singh, B.2    Remotti, F.3    Liu, X.4    Bhat, H.K.5
  • 9
    • 67649329396 scopus 로고    scopus 로고
    • Antioxidant butylated hydroxyanisole inhibits estrogen-induced breast carcinogenesis in female ACI rats
    • Singh B, Mense SM, Remotti F, Liu X, Bhat HK, (2009) Antioxidant butylated hydroxyanisole inhibits estrogen-induced breast carcinogenesis in female ACI rats. J Biochem Mol Toxicol 23: 202-211.
    • (2009) J Biochem Mol Toxicol , vol.23 , pp. 202-211
    • Singh, B.1    Mense, S.M.2    Remotti, F.3    Liu, X.4    Bhat, H.K.5
  • 10
    • 0032537990 scopus 로고    scopus 로고
    • Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study
    • Fisher B, Costantino JP, Wickerham DL, Redmond CK, Kavanah M, et al. (1998) Tamoxifen for prevention of breast cancer: report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study. J Natl Cancer Inst 90: 1371-1388.
    • (1998) J Natl Cancer Inst , vol.90 , pp. 1371-1388
    • Fisher, B.1    Costantino, J.P.2    Wickerham, D.L.3    Redmond, C.K.4    Kavanah, M.5
  • 11
    • 0022416648 scopus 로고
    • Six-year results of a controlled trial of tamoxifen as single adjuvant agent in management of early breast cancer
    • Wilson AJ, Baum M, Brinkley DM, Dossett JA, McPherson K, et al. (1985) Six-year results of a controlled trial of tamoxifen as single adjuvant agent in management of early breast cancer. World J Surg 9: 756-764.
    • (1985) World J Surg , vol.9 , pp. 756-764
    • Wilson, A.J.1    Baum, M.2    Brinkley, D.M.3    Dossett, J.A.4    McPherson, K.5
  • 12
    • 0030667676 scopus 로고    scopus 로고
    • Molecular basis of agonism and antagonism in the oestrogen receptor
    • Brzozowski AM, Pike AC, Dauter Z, Hubbard RE, Bonn T, et al. (1997) Molecular basis of agonism and antagonism in the oestrogen receptor. Nature 389: 753-758.
    • (1997) Nature , vol.389 , pp. 753-758
    • Brzozowski, A.M.1    Pike, A.C.2    Dauter, Z.3    Hubbard, R.E.4    Bonn, T.5
  • 13
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: an overview of the randomised trials
    • Group EBCTC
    • Group EBCTC (1998) Tamoxifen for early breast cancer: an overview of the randomised trials. Lancet 351: 1451-1467.
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 14
    • 55349138386 scopus 로고    scopus 로고
    • ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer
    • Riggins RB, Lan JP, Zhu Y, Klimach U, Zwart A, et al. (2008) ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. Cancer Res 68: 8908-8917.
    • (2008) Cancer Res , vol.68 , pp. 8908-8917
    • Riggins, R.B.1    Lan, J.P.2    Zhu, Y.3    Klimach, U.4    Zwart, A.5
  • 15
    • 0028899660 scopus 로고
    • Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats: promotion by phenobarbital
    • Carthew P, Martin EA, White IN, De Matteis F, Edwards RE, et al. (1995) Tamoxifen induces short-term cumulative DNA damage and liver tumors in rats: promotion by phenobarbital. Cancer Res 55: 544-547.
    • (1995) Cancer Res , vol.55 , pp. 544-547
    • Carthew, P.1    Martin, E.A.2    White, I.N.3    de Matteis, F.4    Edwards, R.E.5
  • 16
    • 0027293895 scopus 로고
    • Gynecologic tumors in tamoxifen-treated women with breast cancer
    • Seoud MA, Johnson J, Weed JC Jr, (1993) Gynecologic tumors in tamoxifen-treated women with breast cancer. Obstet Gynecol 82: 165-169.
    • (1993) Obstet Gynecol , vol.82 , pp. 165-169
    • Seoud, M.A.1    Johnson, J.2    Weed Jr., J.C.3
  • 17
    • 10744230036 scopus 로고    scopus 로고
    • Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling
    • Clarke R, Liu MC, Bouker KB, Gu Z, Lee RY, et al. (2003) Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling. Oncogene 22: 7316-7339.
    • (2003) Oncogene , vol.22 , pp. 7316-7339
    • Clarke, R.1    Liu, M.C.2    Bouker, K.B.3    Gu, Z.4    Lee, R.Y.5
  • 18
    • 27744501473 scopus 로고    scopus 로고
    • Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer
    • Riggins RB, Bouton AH, Liu MC, Clarke R, (2005) Antiestrogens, aromatase inhibitors, and apoptosis in breast cancer. Vitam Horm 71: 201-237.
    • (2005) Vitam Horm , vol.71 , pp. 201-237
    • Riggins, R.B.1    Bouton, A.H.2    Liu, M.C.3    Clarke, R.4
  • 20
    • 0028172242 scopus 로고
    • alpha-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes
    • Phillips DH, Carmichael PL, Hewer A, Cole KJ, Poon GK, (1994) alpha-Hydroxytamoxifen, a metabolite of tamoxifen with exceptionally high DNA-binding activity in rat hepatocytes. Cancer Res 54: 5518-5522.
    • (1994) Cancer Res , vol.54 , pp. 5518-5522
    • Phillips, D.H.1    Carmichael, P.L.2    Hewer, A.3    Cole, K.J.4    Poon, G.K.5
  • 21
    • 0028035492 scopus 로고
    • Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s
    • Styles JA, Davies A, Lim CK, De Matteis F, Stanley LA, et al. (1994) Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s. Carcinogenesis 15: 5-9.
    • (1994) Carcinogenesis , vol.15 , pp. 5-9
    • Styles, J.A.1    Davies, A.2    Lim, C.K.3    de Matteis, F.4    Stanley, L.A.5
  • 22
    • 0028177045 scopus 로고
    • A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes
    • Lim CK, Yuan ZX, Lamb JH, White IN, De Matteis F, et al. (1994) A comparative study of tamoxifen metabolism in female rat, mouse and human liver microsomes. Carcinogenesis 15: 589-593.
    • (1994) Carcinogenesis , vol.15 , pp. 589-593
    • Lim, C.K.1    Yuan, Z.X.2    Lamb, J.H.3    White, I.N.4    de Matteis, F.5
  • 23
    • 0026096161 scopus 로고
    • A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing
    • Crespi CL, Gonzalez FJ, Steimel DT, Turner TR, Gelboin HV, et al. (1991) A metabolically competent human cell line expressing five cDNAs encoding procarcinogen-activating enzymes: application to mutagenicity testing. Chem Res Toxicol 4: 566-572.
    • (1991) Chem Res Toxicol , vol.4 , pp. 566-572
    • Crespi, C.L.1    Gonzalez, F.J.2    Steimel, D.T.3    Turner, T.R.4    Gelboin, H.V.5
  • 24
    • 0026606580 scopus 로고
    • Induction of covalent DNA adducts in rodents by tamoxifen
    • Han XL, Liehr JG, (1992) Induction of covalent DNA adducts in rodents by tamoxifen. Cancer Res 52: 1360-1363.
    • (1992) Cancer Res , vol.52 , pp. 1360-1363
    • Han, X.L.1    Liehr, J.G.2
  • 25
    • 0033858986 scopus 로고    scopus 로고
    • Identification of hepatic tamoxifen-DNA adducts in mice: alpha-(N(2)-deoxyguanosinyl)tamoxifen and alpha-(N(2)-deoxyguanosinyl)tamoxifen N-oxide
    • Umemoto A, Monden Y, Suwa M, Kanno Y, Suzuki M, et al. (2000) Identification of hepatic tamoxifen-DNA adducts in mice: alpha-(N(2)-deoxyguanosinyl)tamoxifen and alpha-(N(2)-deoxyguanosinyl)tamoxifen N-oxide. Carcinogenesis 21: 1737-1744.
    • (2000) Carcinogenesis , vol.21 , pp. 1737-1744
    • Umemoto, A.1    Monden, Y.2    Suwa, M.3    Kanno, Y.4    Suzuki, M.5
  • 26
    • 11144221653 scopus 로고    scopus 로고
    • Prevention of solely estrogen-induced mammary tumors in female aci rats by tamoxifen: evidence for estrogen receptor mediation
    • Li SA, Weroha SJ, Tawfik O, Li JJ, (2002) Prevention of solely estrogen-induced mammary tumors in female aci rats by tamoxifen: evidence for estrogen receptor mediation. J Endocrinol 175: 297-305.
    • (2002) J Endocrinol , vol.175 , pp. 297-305
    • Li, S.A.1    Weroha, S.J.2    Tawfik, O.3    Li, J.J.4
  • 27
    • 0035662989 scopus 로고    scopus 로고
    • Intratumoral variations in DNA ploidy and s-phase fraction in human breast cancer
    • Arnerlov C, Emdin SO, Cajander S, Bengtsson NO, Tavelin B, et al. (2001) Intratumoral variations in DNA ploidy and s-phase fraction in human breast cancer. Anal Cell Pathol 23: 21-28.
    • (2001) Anal Cell Pathol , vol.23 , pp. 21-28
    • Arnerlov, C.1    Emdin, S.O.2    Cajander, S.3    Bengtsson, N.O.4    Tavelin, B.5
  • 28
    • 0036144435 scopus 로고    scopus 로고
    • Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer
    • Li JJ, Papa D, Davis MF, Weroha SJ, Aldaz CM, et al. (2002) Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Mol Carcinog 33: 56-65.
    • (2002) Mol Carcinog , vol.33 , pp. 56-65
    • Li, J.J.1    Papa, D.2    Davis, M.F.3    Weroha, S.J.4    Aldaz, C.M.5
  • 29
    • 0034646213 scopus 로고    scopus 로고
    • Rat strain-specific actions of 17beta-estradiol in the mammary gland: correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers
    • Harvell DM, Strecker TE, Tochacek M, Xie B, Pennington KL, et al. (2000) Rat strain-specific actions of 17beta-estradiol in the mammary gland: correlation between estrogen-induced lobuloalveolar hyperplasia and susceptibility to estrogen-induced mammary cancers. Proc Natl Acad Sci U S A 97: 2779-2784.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 2779-2784
    • Harvell, D.M.1    Strecker, T.E.2    Tochacek, M.3    Xie, B.4    Pennington, K.L.5
  • 30
    • 0031419014 scopus 로고    scopus 로고
    • Ovary-intact, but not ovariectomized female ACI rats treated with 17beta-estradiol rapidly develop mammary carcinoma
    • Shull JD, Spady TJ, Snyder MC, Johansson SL, Pennington KL, (1997) Ovary-intact, but not ovariectomized female ACI rats treated with 17beta-estradiol rapidly develop mammary carcinoma. Carcinogenesis 18: 1595-1601.
    • (1997) Carcinogenesis , vol.18 , pp. 1595-1601
    • Shull, J.D.1    Spady, T.J.2    Snyder, M.C.3    Johansson, S.L.4    Pennington, K.L.5
  • 31
    • 77955272128 scopus 로고    scopus 로고
    • Dietary quercetin exacerbates the development of estrogen-induced breast tumors in female ACI rats
    • Singh B, Mense SM, Bhat NK, Putty S, Guthiel WA, et al. (2010) Dietary quercetin exacerbates the development of estrogen-induced breast tumors in female ACI rats. Toxicol Appl Pharmacol 247: 83-90.
    • (2010) Toxicol Appl Pharmacol , vol.247 , pp. 83-90
    • Singh, B.1    Mense, S.M.2    Bhat, N.K.3    Putty, S.4    Guthiel, W.A.5
  • 32
    • 11144228109 scopus 로고    scopus 로고
    • Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats
    • Li JJ, Weroha SJ, Lingle WL, Papa D, Salisbury JL, et al. (2004) Estrogen mediates Aurora-A overexpression, centrosome amplification, chromosomal instability, and breast cancer in female ACI rats. Proc Natl Acad Sci U S A 101: 18123-18128.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 18123-18128
    • Li, J.J.1    Weroha, S.J.2    Lingle, W.L.3    Papa, D.4    Salisbury, J.L.5
  • 34
    • 33644863026 scopus 로고    scopus 로고
    • Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats
    • Weroha SJ, Li SA, Tawfik O, Li JJ, (2006) Overexpression of cyclins D1 and D3 during estrogen-induced breast oncogenesis in female ACI rats. Carcinogenesis 27: 491-498.
    • (2006) Carcinogenesis , vol.27 , pp. 491-498
    • Weroha, S.J.1    Li, S.A.2    Tawfik, O.3    Li, J.J.4
  • 35
    • 78650208471 scopus 로고    scopus 로고
    • Amphiregulin Mediates Estrogen, Progesterone, and EGFR Signaling in the Normal Rat Mammary Gland and in Hormone-Dependent Rat Mammary Cancers
    • Kariagina A, Xie J, Leipprandt JR, Haslam SZ, (2010) Amphiregulin Mediates Estrogen, Progesterone, and EGFR Signaling in the Normal Rat Mammary Gland and in Hormone-Dependent Rat Mammary Cancers. Horm Cancer 1: 229-244.
    • (2010) Horm Cancer , vol.1 , pp. 229-244
    • Kariagina, A.1    Xie, J.2    Leipprandt, J.R.3    Haslam, S.Z.4
  • 36
    • 24044525270 scopus 로고    scopus 로고
    • c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells
    • Mukherjee S, Conrad SE, (2005) c-Myc suppresses p21WAF1/CIP1 expression during estrogen signaling and antiestrogen resistance in human breast cancer cells. J Biol Chem 280: 17617-17625.
    • (2005) J Biol Chem , vol.280 , pp. 17617-17625
    • Mukherjee, S.1    Conrad, S.E.2
  • 37
    • 1542270862 scopus 로고    scopus 로고
    • Differential oxidant potential of carcinogenic and weakly carcinogenic estrogens: Involvement of metabolic activation and cytochrome P450
    • Patel MM, Bhat HK, (2004) Differential oxidant potential of carcinogenic and weakly carcinogenic estrogens: Involvement of metabolic activation and cytochrome P450. J Biochem Mol Toxicol 18: 37-42.
    • (2004) J Biochem Mol Toxicol , vol.18 , pp. 37-42
    • Patel, M.M.1    Bhat, H.K.2
  • 38
    • 14944354257 scopus 로고    scopus 로고
    • A unifying mechanism in the initiation of cancer and other diseases by catechol quinones
    • Cavalieri EL, Rogan EG, (2004) A unifying mechanism in the initiation of cancer and other diseases by catechol quinones. Ann N Y Acad Sci 1028: 247-257.
    • (2004) Ann N Y Acad Sci , vol.1028 , pp. 247-257
    • Cavalieri, E.L.1    Rogan, E.G.2
  • 39
    • 0023181602 scopus 로고
    • Estrogen carcinogenesis in Syrian hamster tissues: role of metabolism
    • Li JJ, Li SA, (1987) Estrogen carcinogenesis in Syrian hamster tissues: role of metabolism. Fed Proc 46: 1858-1863.
    • (1987) Fed Proc , vol.46 , pp. 1858-1863
    • Li, J.J.1    Li, S.A.2
  • 41
    • 0033655698 scopus 로고    scopus 로고
    • Endogenous estrogens as carcinogens through metabolic activation
    • Yager JD, (2000) Endogenous estrogens as carcinogens through metabolic activation. J Natl Cancer Inst Monogr pp. 67-73.
    • (2000) J Natl Cancer Inst Monogr , pp. 67-73
    • Yager, J.D.1
  • 42
    • 14344251109 scopus 로고    scopus 로고
    • The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediates
    • Vitseva O, Flockhart DA, Jin Y, Varghese S, Freedman JE, (2005) The effects of tamoxifen and its metabolites on platelet function and release of reactive oxygen intermediates. J Pharmacol Exp Ther 312: 1144-1150.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 1144-1150
    • Vitseva, O.1    Flockhart, D.A.2    Jin, Y.3    Varghese, S.4    Freedman, J.E.5
  • 43
    • 1642422891 scopus 로고    scopus 로고
    • Estrogen receptor-mediated regulation of oxidative stress and DNA damage in breast cancer
    • Mobley JA, Brueggemeier RW, (2004) Estrogen receptor-mediated regulation of oxidative stress and DNA damage in breast cancer. Carcinogenesis 25: 3-9.
    • (2004) Carcinogenesis , vol.25 , pp. 3-9
    • Mobley, J.A.1    Brueggemeier, R.W.2
  • 44
    • 34249309939 scopus 로고    scopus 로고
    • Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis
    • Montano MM, Chaplin LJ, Deng H, Mesia-Vela S, Gaikwad N, et al. (2007) Protective roles of quinone reductase and tamoxifen against estrogen-induced mammary tumorigenesis. Oncogene 26: 3587-3590.
    • (2007) Oncogene , vol.26 , pp. 3587-3590
    • Montano, M.M.1    Chaplin, L.J.2    Deng, H.3    Mesia-Vela, S.4    Gaikwad, N.5
  • 45
    • 0036850662 scopus 로고    scopus 로고
    • Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA
    • Boocock DJ, Brown K, Gibbs AH, Sanchez E, Turteltaub KW, et al. (2002) Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA. Carcinogenesis 23: 1897-1901.
    • (2002) Carcinogenesis , vol.23 , pp. 1897-1901
    • Boocock, D.J.1    Brown, K.2    Gibbs, A.H.3    Sanchez, E.4    Turteltaub, K.W.5
  • 46
    • 0030812209 scopus 로고    scopus 로고
    • CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver
    • Dehal SS, Kupfer D, (1997) CYP2D6 catalyzes tamoxifen 4-hydroxylation in human liver. Cancer Res 57: 3402-3406.
    • (1997) Cancer Res , vol.57 , pp. 3402-3406
    • Dehal, S.S.1    Kupfer, D.2
  • 47
    • 4243063941 scopus 로고    scopus 로고
    • Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6
    • Desta Z, Ward BA, Soukhova NV, Flockhart DA, (2004) Comprehensive evaluation of tamoxifen sequential biotransformation by the human cytochrome P450 system in vitro: prominent roles for CYP3A and CYP2D6. J Pharmacol Exp Ther 310: 1062-1075.
    • (2004) J Pharmacol Exp Ther , vol.310 , pp. 1062-1075
    • Desta, Z.1    Ward, B.A.2    Soukhova, N.V.3    Flockhart, D.A.4
  • 48
    • 0037329175 scopus 로고    scopus 로고
    • CYP2D6-mediated catalysis of tamoxifen aromatic hydroxylation with an NIH shift: similar hydroxylation mechanism in chicken, rat and human liver microsomes
    • Hu Y, Dehal SS, Hynd G, Jones GB, Kupfer D, (2003) CYP2D6-mediated catalysis of tamoxifen aromatic hydroxylation with an NIH shift: similar hydroxylation mechanism in chicken, rat and human liver microsomes. Xenobiotica 33: 141-151.
    • (2003) Xenobiotica , vol.33 , pp. 141-151
    • Hu, Y.1    Dehal, S.S.2    Hynd, G.3    Jones, G.B.4    Kupfer, D.5
  • 49
    • 33646712592 scopus 로고    scopus 로고
    • The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines
    • Krueger SK, Vandyke JE, Williams DE, Hines RN, (2006) The role of flavin-containing monooxygenase (FMO) in the metabolism of tamoxifen and other tertiary amines. Drug Metab Rev 38: 139-147.
    • (2006) Drug Metab Rev , vol.38 , pp. 139-147
    • Krueger, S.K.1    Vandyke, J.E.2    Williams, D.E.3    Hines, R.N.4
  • 50
    • 24944435434 scopus 로고    scopus 로고
    • Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin
    • Parte P, Kupfer D, (2005) Oxidation of tamoxifen by human flavin-containing monooxygenase (FMO) 1 and FMO3 to tamoxifen-N-oxide and its novel reduction back to tamoxifen by human cytochromes P450 and hemoglobin. Drug Metab Dispos 33: 1446-1452.
    • (2005) Drug Metab Dispos , vol.33 , pp. 1446-1452
    • Parte, P.1    Kupfer, D.2
  • 51
    • 27844511538 scopus 로고    scopus 로고
    • Selective estrogen receptor modulators (SERMs): mechanisms of anticarcinogenesis and drug resistance
    • Lewis JS, Jordan VC, (2005) Selective estrogen receptor modulators (SERMs): mechanisms of anticarcinogenesis and drug resistance. Mutat Res 591: 247-263.
    • (2005) Mutat Res , vol.591 , pp. 247-263
    • Lewis, J.S.1    Jordan, V.C.2
  • 52
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, et al. (1998) The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 95: 927-937.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5
  • 53
    • 41149106833 scopus 로고    scopus 로고
    • Effects of estrogen on gene expression profiles in mouse hypothalamus and white adipose tissue: target genes include glutathione peroxidase 3 and cell death-inducing DNA fragmentation factor, alpha-subunit-like effector A
    • Lundholm L, Putnik M, Otsuki M, Andersson S, Ohlsson C, et al. (2008) Effects of estrogen on gene expression profiles in mouse hypothalamus and white adipose tissue: target genes include glutathione peroxidase 3 and cell death-inducing DNA fragmentation factor, alpha-subunit-like effector A. J Endocrinol 196: 547-557.
    • (2008) J Endocrinol , vol.196 , pp. 547-557
    • Lundholm, L.1    Putnik, M.2    Otsuki, M.3    Andersson, S.4    Ohlsson, C.5
  • 54
    • 33745655207 scopus 로고    scopus 로고
    • Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors
    • Zhang Z, Chen K, Shih JC, Teng CT, (2006) Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors. Mol Endocrinol 20: 1547-1561.
    • (2006) Mol Endocrinol , vol.20 , pp. 1547-1561
    • Zhang, Z.1    Chen, K.2    Shih, J.C.3    Teng, C.T.4
  • 55
    • 65549129063 scopus 로고    scopus 로고
    • Metabolism of histamine in tissues of primary ductal breast cancer
    • von Mach-Szczypinski J, Stanosz S, Sieja K, Stanosz M, (2009) Metabolism of histamine in tissues of primary ductal breast cancer. Metabolism 58: 867-870.
    • (2009) Metabolism , vol.58 , pp. 867-870
    • von Mach-Szczypinski, J.1    Stanosz, S.2    Sieja, K.3    Stanosz, M.4
  • 56
    • 0032080022 scopus 로고    scopus 로고
    • CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor
    • Inohara N, Koseki T, Chen S, Wu X, Nunez G, (1998) CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. EMBO J 17: 2526-2533.
    • (1998) EMBO J , vol.17 , pp. 2526-2533
    • Inohara, N.1    Koseki, T.2    Chen, S.3    Wu, X.4    Nunez, G.5
  • 57
    • 0037442523 scopus 로고    scopus 로고
    • Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family
    • Liang L, Zhao M, Xu Z, Yokoyama KK, Li T, (2003) Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family. Biochem J 370: 195-203.
    • (2003) Biochem J , vol.370 , pp. 195-203
    • Liang, L.1    Zhao, M.2    Xu, Z.3    Yokoyama, K.K.4    Li, T.5
  • 58
    • 0036633164 scopus 로고    scopus 로고
    • Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells
    • Clark AS, West K, Streicher S, Dennis PA, (2002) Constitutive and inducible Akt activity promotes resistance to chemotherapy, trastuzumab, or tamoxifen in breast cancer cells. Mol Cancer Ther 1: 707-717.
    • (2002) Mol Cancer Ther , vol.1 , pp. 707-717
    • Clark, A.S.1    West, K.2    Streicher, S.3    Dennis, P.A.4
  • 59
    • 0032570704 scopus 로고    scopus 로고
    • Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells
    • Lee YJ, Galoforo SS, Berns CM, Chen JC, Davis BH, et al. (1998) Glucose deprivation-induced cytotoxicity and alterations in mitogen-activated protein kinase activation are mediated by oxidative stress in multidrug-resistant human breast carcinoma cells. J Biol Chem 273: 5294-5299.
    • (1998) J Biol Chem , vol.273 , pp. 5294-5299
    • Lee, Y.J.1    Galoforo, S.S.2    Berns, C.M.3    Chen, J.C.4    Davis, B.H.5
  • 60
    • 2942652871 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer
    • Shou J, Massarweh S, Osborne CK, Wakeling AE, Ali S, et al. (2004) Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/HER2-positive breast cancer. J Natl Cancer Inst 96: 926-935.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 926-935
    • Shou, J.1    Massarweh, S.2    Osborne, C.K.3    Wakeling, A.E.4    Ali, S.5
  • 61
    • 0036838768 scopus 로고    scopus 로고
    • Protective effects of estrogen and selective estrogen receptor modulators in the brain
    • Dhandapani KM, Brann DW, (2002) Protective effects of estrogen and selective estrogen receptor modulators in the brain. Biol Reprod 67: 1379-1385.
    • (2002) Biol Reprod , vol.67 , pp. 1379-1385
    • Dhandapani, K.M.1    Brann, D.W.2
  • 62
    • 0035831020 scopus 로고    scopus 로고
    • Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity
    • Kousteni S, Bellido T, Plotkin LI, O'Brien CA, Bodenner DL, et al. (2001) Nongenotropic, sex-nonspecific signaling through the estrogen or androgen receptors: dissociation from transcriptional activity. Cell 104: 719-730.
    • (2001) Cell , vol.104 , pp. 719-730
    • Kousteni, S.1    Bellido, T.2    Plotkin, L.I.3    O'Brien, C.A.4    Bodenner, D.L.5
  • 63
    • 0037184912 scopus 로고    scopus 로고
    • Integration of the non-genomic and genomic actions of estrogen. Membrane-initiated signaling by steroid to transcription and cell biology
    • Pedram A, Razandi M, Aitkenhead M, Hughes CC, Levin ER, (2002) Integration of the non-genomic and genomic actions of estrogen. Membrane-initiated signaling by steroid to transcription and cell biology. J Biol Chem 277: 50768-50775.
    • (2002) J Biol Chem , vol.277 , pp. 50768-50775
    • Pedram, A.1    Razandi, M.2    Aitkenhead, M.3    Hughes, C.C.4    Levin, E.R.5
  • 64
    • 0028234634 scopus 로고
    • DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: hormone-induced free radical damage preceding renal malignancy
    • Han X, Liehr JG, (1994) DNA single-strand breaks in kidneys of Syrian hamsters treated with steroidal estrogens: hormone-induced free radical damage preceding renal malignancy. Carcinogenesis 15: 997-1000.
    • (1994) Carcinogenesis , vol.15 , pp. 997-1000
    • Han, X.1    Liehr, J.G.2
  • 65
    • 0027385996 scopus 로고
    • Localization of estrogen receptors in interstitial cells of hamster kidney and in estradiol-induced renal tumors as evidence of the mesenchymal origin of this neoplasm
    • Bhat HK, Hacker HJ, Bannasch P, Thompson EA, Liehr JG, (1993) Localization of estrogen receptors in interstitial cells of hamster kidney and in estradiol-induced renal tumors as evidence of the mesenchymal origin of this neoplasm. Cancer Res 53: 5447-5451.
    • (1993) Cancer Res , vol.53 , pp. 5447-5451
    • Bhat, H.K.1    Hacker, H.J.2    Bannasch, P.3    Thompson, E.A.4    Liehr, J.G.5
  • 66
    • 0019281470 scopus 로고
    • Distribution of CuZn superoxide dismutase and Mn superoxide dismutase in human tissues and extracellular fluids
    • Marklund S, (1980) Distribution of CuZn superoxide dismutase and Mn superoxide dismutase in human tissues and extracellular fluids. Acta Physiol Scand Suppl 492: 19-23.
    • (1980) Acta Physiol Scand , vol.SUPPL. 492 , pp. 19-23
    • Marklund, S.1
  • 67
    • 13244295677 scopus 로고    scopus 로고
    • Suppression of calbindin D28K in estrogen-induced hamster renal tumors
    • Bhat HK, Epelboym I, (2004) Suppression of calbindin D28K in estrogen-induced hamster renal tumors. J Steroid Biochem Mol Biol 92: 391-398.
    • (2004) J Steroid Biochem Mol Biol , vol.92 , pp. 391-398
    • Bhat, H.K.1    Epelboym, I.2
  • 68
    • 0035584274 scopus 로고    scopus 로고
    • Importance of complete DNA digestion in minimizing variability of 8-oxo-dG analyses
    • Huang X, Powell J, Mooney LA, Li C, Frenkel K, (2001) Importance of complete DNA digestion in minimizing variability of 8-oxo-dG analyses. Free Radic Biol Med 31: 1341-1351.
    • (2001) Free Radic Biol Med , vol.31 , pp. 1341-1351
    • Huang, X.1    Powell, J.2    Mooney, L.A.3    Li, C.4    Frenkel, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.