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Volumn 6, Issue 9, 2011, Pages

Transgene excision has no impact on in vivo integration of human iPS derived neural precursors

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; MYC PROTEIN; VIRUS PROTEIN; VIRUS VECTOR; DOUBLECORTIN PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; NEUROPEPTIDE; TUBULIN;

EID: 80053067542     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0024687     Document Type: Article
Times cited : (17)

References (42)
  • 1
    • 36248966518 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult human fibroblasts by defined factors
    • Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, et al. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-72.
    • (2007) Cell , vol.131 , pp. 861-872
    • Takahashi, K.1    Tanabe, K.2    Ohnuki, M.3    Narita, M.4    Ichisaka, T.5
  • 2
    • 34249908901 scopus 로고    scopus 로고
    • In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
    • Wernig M, Meissner A, Foreman R, Brambrink, Ku M, et al. (2007) In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state. Nature 448: 318-324.
    • (2007) Nature , vol.448 , pp. 318-324
    • Wernig, M.1    Meissner, A.2    Foreman, R.3    Brambrink4    Ku, M.5
  • 3
  • 4
    • 79952264847 scopus 로고    scopus 로고
    • Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells
    • Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, et al. (2011) Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells. Nature 471: 68-73.
    • (2011) Nature , vol.471 , pp. 68-73
    • Lister, R.1    Pelizzola, M.2    Kida, Y.S.3    Hawkins, R.D.4    Nery, J.R.5
  • 5
    • 77957598016 scopus 로고    scopus 로고
    • iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability
    • Ramos-Mejia V, Muñoz-Lopez M, Garcia-Perez JL, Menendez P, (2010) iPSC lines that do not silence the expression of the ectopic reprogramming factors may display enhanced propensity to genomic instability. Cell Research 20: 1092-5.
    • (2010) Cell Research , vol.20 , pp. 1092-1095
    • Ramos-Mejia, V.1    Muñoz-Lopez, M.2    Garcia-Perez, J.L.3    Menendez, P.4
  • 6
    • 77955449906 scopus 로고    scopus 로고
    • Epigenetic memory in induced pluripotent stem cells
    • Kim K, Doi A, Wen B, Ng K, Zhao R, et al. (2010) Epigenetic memory in induced pluripotent stem cells. Nature 467: 285-90.
    • (2010) Nature , vol.467 , pp. 285-290
    • Kim, K.1    Doi, A.2    Wen, B.3    Ng, K.4    Zhao, R.5
  • 7
    • 78650752402 scopus 로고    scopus 로고
    • Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
    • Polo JM, Liu S, Figueroa ME, Kulalert W, Eminli S, et al. (2010) Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells. Nature Biotechnology 28: 848-55.
    • (2010) Nature Biotechnology , vol.28 , pp. 848-855
    • Polo, J.M.1    Liu, S.2    Figueroa, M.E.3    Kulalert, W.4    Eminli, S.5
  • 8
    • 77952425747 scopus 로고    scopus 로고
    • Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
    • Stadtfeld M, Apostolou E, Akutsu H, Fukuda A, Follett P, et al. (2010) Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature 465: 175-81.
    • (2010) Nature , vol.465 , pp. 175-181
    • Stadtfeld, M.1    Apostolou, E.2    Akutsu, H.3    Fukuda, A.4    Follett, P.5
  • 9
    • 61349100729 scopus 로고    scopus 로고
    • Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors
    • Soldner F, Hockemeyer D, Beard C, Gao Q, Bell GW, et al. (2009) Parkinson's disease patient-derived induced pluripotent stem cells free of viral reprogramming factors. Cell 136: 964-77.
    • (2009) Cell , vol.136 , pp. 964-977
    • Soldner, F.1    Hockemeyer, D.2    Beard, C.3    Gao, Q.4    Bell, G.W.5
  • 10
    • 22444449591 scopus 로고    scopus 로고
    • Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain
    • Tabar V, Panagiotakos G, Greenberg E, Chan BK, Sadelain M, et al. (2005) Migration and differentiation of neural precursors derived from human embryonic stem cells in the rat brain. Nature Biotechnology 23: 601-606.
    • (2005) Nature Biotechnology , vol.23 , pp. 601-606
    • Tabar, V.1    Panagiotakos, G.2    Greenberg, E.3    Chan, B.K.4    Sadelain, M.5
  • 11
    • 38349062515 scopus 로고    scopus 로고
    • Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage
    • Elkabetz Y, Panagiotakos G, Shamy G, (2008) Human ES cell-derived neural rosettes reveal a functionally distinct early neural stem cell stage. Genes & Dev 22: 152-65.
    • (2008) Genes & Dev , vol.22 , pp. 152-165
    • Elkabetz, Y.1    Panagiotakos, G.2    Shamy, G.3
  • 12
    • 62149125434 scopus 로고    scopus 로고
    • Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
    • Chambers SM, Fasano CA, Papapetrou EP, Tomishima M, Sadelain M, et al. (2009) Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nature Biotechnology 27: 275-280.
    • (2009) Nature Biotechnology , vol.27 , pp. 275-280
    • Chambers, S.M.1    Fasano, C.A.2    Papapetrou, E.P.3    Tomishima, M.4    Sadelain, M.5
  • 14
    • 77957670482 scopus 로고    scopus 로고
    • Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats
    • Hargus G, Cooper O, Deleidi M, Levy A, Lee K, et al. (2010) Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proceedings of the National Academy of Sciences 107: 15921-6.
    • (2010) Proceedings of the National Academy of Sciences , vol.107 , pp. 15921-15926
    • Hargus, G.1    Cooper, O.2    Deleidi, M.3    Levy, A.4    Lee, K.5
  • 15
    • 0033040497 scopus 로고    scopus 로고
    • Subventricular zone astrocytes are neural stem cells in the adult mammalian brain
    • Doetsch F, Caille I, Lim DA, Garcia-Verdugo JM, Alvarez-Buylla A, (1999) Subventricular zone astrocytes are neural stem cells in the adult mammalian brain. Cell 97: 703-716.
    • (1999) Cell , vol.97 , pp. 703-716
    • Doetsch, F.1    Caille, I.2    Lim, D.A.3    Garcia-Verdugo, J.M.4    Alvarez-Buylla, A.5
  • 16
    • 0030979469 scopus 로고    scopus 로고
    • Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain
    • Doetsch F, GarciaVerdugo JM, AlvarezBuylla A, (1997) Cellular composition and three-dimensional organization of the subventricular germinal zone in the adult mammalian brain. Journal of Neuroscience 17: 5046-5071.
    • (1997) Journal of Neuroscience , vol.17 , pp. 5046-5071
    • Doetsch, F.1    GarciaVerdugo, J.M.2    AlvarezBuylla, A.3
  • 18
    • 0037204595 scopus 로고    scopus 로고
    • Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain
    • Englund U, Bjorklund A, Wictorin K, (2002) Migration patterns and phenotypic differentiation of long-term expanded human neural progenitor cells after transplantation into the adult rat brain. Developmental Brain Research 134: 123-141.
    • (2002) Developmental Brain Research , vol.134 , pp. 123-141
    • Englund, U.1    Bjorklund, A.2    Wictorin, K.3
  • 19
    • 36148955544 scopus 로고    scopus 로고
    • Long-term impact of radiation on the stem cell and oligodendrocyte precursors in the brain
    • Panagiotakos G, Alshamy G, Chan B, Abrams R, Greenberg E, et al. (2007) Long-term impact of radiation on the stem cell and oligodendrocyte precursors in the brain. PloS one 2: e588.
    • (2007) PloS One , vol.2
    • Panagiotakos, G.1    Alshamy, G.2    Chan, B.3    Abrams, R.4    Greenberg, E.5
  • 20
    • 79957855262 scopus 로고    scopus 로고
    • Reprogramming of mouse and human cells to pluripotency using mature microRNAs
    • Miyoshi N, Ishii H, Nagano H, Haraguchi N, Dewi DL, et al. (2011) Reprogramming of mouse and human cells to pluripotency using mature microRNAs. Cell Stem Cell 8: 633-8.
    • (2011) Cell Stem Cell , vol.8 , pp. 633-638
    • Miyoshi, N.1    Ishii, H.2    Nagano, H.3    Haraguchi, N.4    Dewi, D.L.5
  • 21
    • 77649275936 scopus 로고    scopus 로고
    • A nonviral minicircle vector for deriving human iPS cells
    • Jia F, Wilson KD, Sun N, Gupta DM, Huang M, et al. (2010) A nonviral minicircle vector for deriving human iPS cells. Nature Methods 7: 197-9.
    • (2010) Nature Methods , vol.7 , pp. 197-199
    • Jia, F.1    Wilson, K.D.2    Sun, N.3    Gupta, D.M.4    Huang, M.5
  • 22
    • 72849137462 scopus 로고    scopus 로고
    • Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells
    • Zhou W, Freed CR, (2009) Adenoviral gene delivery can reprogram human fibroblasts to induced pluripotent stem cells. Stem cells (Dayton, Ohio) 27: 2667-74.
    • (2009) Stem Cells (Dayton, Ohio) , vol.27 , pp. 2667-2674
    • Zhou, W.1    Freed, C.R.2
  • 23
    • 79953021243 scopus 로고    scopus 로고
    • Development of defective and persistent sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming
    • Nishimura K, Sano M, Ohtaka M, Furuta B, Umemura Y, et al. (2011) Development of defective and persistent sendai virus vector: a unique gene delivery/expression system ideal for cell reprogramming. The Journal of Biological Chemistry 286: 4760-4771.
    • (2011) The Journal of Biological Chemistry , vol.286 , pp. 4760-4771
    • Nishimura, K.1    Sano, M.2    Ohtaka, M.3    Furuta, B.4    Umemura, Y.5
  • 24
    • 70450265981 scopus 로고    scopus 로고
    • Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proceedings of the Japan Academy
    • Fusaki N, Ban H, Nishiyama A, Saeki K, Hasegawa M, (2009) Efficient induction of transgene-free human pluripotent stem cells using a vector based on Sendai virus, an RNA virus that does not integrate into the host genome. Proceedings of the Japan Academy. Series B, Physical and Biological sciences 85: 348-62.
    • (2009) Series B, Physical and Biological Sciences , vol.85 , pp. 348-362
    • Fusaki, N.1    Ban, H.2    Nishiyama, A.3    Saeki, K.4    Hasegawa, M.5
  • 25
    • 77958536106 scopus 로고    scopus 로고
    • Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA
    • Warren L, Manos P, Ahfeldt T, Lo YH, Li H, et al. (2010) Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA. Cell Stem Cell 7: 618-30.
    • (2010) Cell Stem Cell , vol.7 , pp. 618-630
    • Warren, L.1    Manos, P.2    Ahfeldt, T.3    Lo, Y.H.4    Li, H.5
  • 26
    • 77955437362 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation
    • Cho HJ, Lee CS, Kwon YW, Paek JS, Lee SH, et al. (2010) Induction of pluripotent stem cells from adult somatic cells by protein-based reprogramming without genetic manipulation. Blood 116: 386-95.
    • (2010) Blood , vol.116 , pp. 386-395
    • Cho, H.J.1    Lee, C.S.2    Kwon, Y.W.3    Paek, J.S.4    Lee, S.H.5
  • 27
    • 66049135249 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells using recombinant proteins
    • Zhou H, Wu S, Joo JY, Zhu S, Han DW, et al. (2009) Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell 4: 381-384.
    • (2009) Cell Stem Cell , vol.4 , pp. 381-384
    • Zhou, H.1    Wu, S.2    Joo, J.Y.3    Zhu, S.4    Han, D.W.5
  • 28
    • 77953095927 scopus 로고    scopus 로고
    • Using small molecules to improve generation of induced pluripotent stem cells from somatic cells
    • Desponts C, Ding S, (2010) Using small molecules to improve generation of induced pluripotent stem cells from somatic cells. Methods in Molecular Biology 636: 207-18.
    • (2010) Methods in Molecular Biology , vol.636 , pp. 207-218
    • Desponts, C.1    Ding, S.2
  • 29
    • 73349124768 scopus 로고    scopus 로고
    • Non cell-autonomous reprogramming of adult ocular progenitors: generation of pluripotent stem cells without exogenous transcription factors
    • Balasubramanian S, Babai N, Chaudhuri A, Qiu F, Bhattacharya S, et al. (2009) Non cell-autonomous reprogramming of adult ocular progenitors: generation of pluripotent stem cells without exogenous transcription factors. Stem cells (Dayton, Ohio) 27: 3053-62.
    • (2009) Stem Cells (Dayton, Ohio) , vol.27 , pp. 3053-3062
    • Balasubramanian, S.1    Babai, N.2    Chaudhuri, A.3    Qiu, F.4    Bhattacharya, S.5
  • 30
    • 71549120380 scopus 로고    scopus 로고
    • The role of Myc-induced protein synthesis in cancer
    • Ruggero D, (2009) The role of Myc-induced protein synthesis in cancer. Cancer Research 69: 8839-8843.
    • (2009) Cancer Research , vol.69 , pp. 8839-8843
    • Ruggero, D.1
  • 31
    • 79953058250 scopus 로고    scopus 로고
    • The tumorigenicity of human embryonic and induced pluripotent stem cells
    • Ben-David U, Benvenisty N, (2011) The tumorigenicity of human embryonic and induced pluripotent stem cells. Nature Reviews Cancer 11: 268-77.
    • (2011) Nature Reviews Cancer , vol.11 , pp. 268-277
    • Ben-David, U.1    Benvenisty, N.2
  • 32
    • 34249880066 scopus 로고    scopus 로고
    • Generation of germline-competent induced pluripotent stem cells
    • Okita K, Ichisaka T, Yamanaka S, (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-317.
    • (2007) Nature , vol.448 , pp. 313-317
    • Okita, K.1    Ichisaka, T.2    Yamanaka, S.3
  • 33
    • 75349095926 scopus 로고    scopus 로고
    • Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector
    • Sommer C, Sommer A, Longmire TA, Christodoulou C, Thomas DD, et al. (2010) Excision of reprogramming transgenes improves the differentiation potential of iPS cells generated with a single excisable vector. Stem Cells 28: 64-74.
    • (2010) Stem Cells , vol.28 , pp. 64-74
    • Sommer, C.1    Sommer, A.2    Longmire, T.A.3    Christodoulou, C.4    Thomas, D.D.5
  • 34
    • 66149165885 scopus 로고    scopus 로고
    • Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells
    • Chang CW, Lai YS, Pawlik KM, Liu K, Sun CW, et al. (2009) Polycistronic lentiviral vector for "hit and run" reprogramming of adult skin fibroblasts to induced pluripotent stem cells. Stem cells (Dayton, Ohio) 27: 1042-9.
    • (2009) Stem Cells (Dayton, Ohio) , vol.27 , pp. 1042-1049
    • Chang, C.W.1    Lai, Y.S.2    Pawlik, K.M.3    Liu, K.4    Sun, C.W.5
  • 35
    • 64749111225 scopus 로고    scopus 로고
    • Virus-free induction of pluripotency and subsequent excision of reprogramming factors
    • Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, et al. (2009) Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature 458: 771-5.
    • (2009) Nature , vol.458 , pp. 771-775
    • Kaji, K.1    Norrby, K.2    Paca, A.3    Mileikovsky, M.4    Mohseni, P.5
  • 36
    • 77958569435 scopus 로고    scopus 로고
    • Induced pluripotency: history, mechanisms, and applications
    • Stadtfeld M, Hochedlinger K, (2010) Induced pluripotency: history, mechanisms, and applications. Genes & Development 24: 2239-2263.
    • (2010) Genes & Development , vol.24 , pp. 2239-2263
    • Stadtfeld, M.1    Hochedlinger, K.2
  • 39
    • 79957795795 scopus 로고    scopus 로고
    • miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells
    • Kim H, Lee G, Ganat Y, Papapetrou EP, Lipchina I, et al. (2011) miR-371-3 Expression Predicts Neural Differentiation Propensity in Human Pluripotent Stem Cells. Cell Stem Cell 8: 695-706.
    • (2011) Cell Stem Cell , vol.8 , pp. 695-706
    • Kim, H.1    Lee, G.2    Ganat, Y.3    Papapetrou, E.P.4    Lipchina, I.5
  • 40
    • 34247475338 scopus 로고    scopus 로고
    • Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons
    • Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, et al. (2007) Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nature Neuroscience 10: 615-22.
    • (2007) Nature Neuroscience , vol.10 , pp. 615-622
    • Nagai, M.1    Re, D.B.2    Nagata, T.3    Chalazonitis, A.4    Jessell, T.M.5
  • 41
    • 34247473080 scopus 로고    scopus 로고
    • Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model
    • Di Giorgio F P, Carrasco MA, Siao MC, Maniatis T, Eggan K, (2007) Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nature Neuroscience 10: 608-14.
    • (2007) Nature Neuroscience , vol.10 , pp. 608-614
    • Di Giorgio, F.P.1    Carrasco, M.A.2    Siao, M.C.3    Maniatis, T.4    Eggan, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.