Acceleration of neuronal precursors differentiation induced by substrate nanotopography

Biotechnology and Bioengineering

Volumn 108, Issue 11, 2011, Pages 2736-2746

  Migliorini, Elisa ^a,b   Grenci, Gianluca ^a   Ban, Jelena ^c   Pozzato, Alessandro ^a   Tormen, Massimo ^a   Lazzarino, Marco ^a,b   Torre, Vincent ^c,d   Ruaro, Maria Elisabetta ^c,e  

^a IOM CNR LABORATORIO TASC   (Italy)

^b CBM Scrl   (Italy)

^c SISSA   (Italy)

^d ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^e Glance Vision Technologies   (Italy)

Author keywords

Embryonic stem cells; Nanotopography; Neuronal differentiation; Pillar; Polydimethylsiloxane

Indexed keywords

CELL BIOLOGY; CELL LINEAGE; EMBRYONIC STEM CELLS; GLASS COVERSLIPS; LATERAL RESOLUTION; NANOTOPOGRAPHIES; NEURONAL DIFFERENTIATION; PDMS NANOPILLARS; PILLAR; PILLAR ARRAYS; POLYDIMETHYLSILOXANE PDMS; REGENERATIVE MEDICINE;

BIOMECHANICS; MECHANICAL PROPERTIES; MICROCHANNELS; NANOTECHNOLOGY; POLYDIMETHYLSILOXANE; SILICONES; STEM CELLS; SUBSTRATES;

CELL CULTURE;

DIMETICONE; NANOMATERIAL;

ACCELERATION; ANIMAL CELL; ARTICLE; CELL ADHESION; CELL LINEAGE; EMBRYONIC STEM CELL; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; TOPOGRAPHY;

ANIMALS; CELL CULTURE TECHNIQUES; CELL DIFFERENTIATION; CELL PROLIFERATION; DIMETHYLPOLYSILOXANES; EMBRYONIC STEM CELLS; MICE; NANOSTRUCTURES; NEURONS; SURFACE PROPERTIES;

EID: 80053054141     PISSN: 00063592     EISSN: 10970290     Source Type: Journal    
DOI: 10.1002/bit.23232     Document Type: Article

References (45)

1. Angers-Loustau A, Cote JF, Charest A, Dowbenko D, Spencer S, Lasky LA, Tremblay ML. 1999. Protein tyrosine phosphorylation-PEST regulates focal adhesion disassmbly, migration, and cytokinesis in fibroblasts. J.Cell Biol 144: 1019-1031.
2. Arnhold S, Lenartz D, Kruttwig K, Klinz FJ, Kolossov E, Hescheler J, Sturm V, Andressen C, Addicks K. 2000. Differentiation of green fluorescent protein-labeled embryonic stem cell-derived neural precursor cells into Thy-1-positive neurons and glia after transplantation into adult rat striatum. J Neurosurg 93: 1026-1032.
3. Ban J, Bonifazi P, Pinato G, Broccard FD, Studer L, Torre V, Ruaro ME. 2007. Embryonic stem cell-derived neurons form functional networks in vitro. Stem Cell 25: 738-749.
4. Barberi T, Klivenyi P, Calingasan NY, Lee H, Kawamata H, Loonam K, Perrier AL, Bruses J, Rubio ME, Topf N, Tabar V, Harrison NL, Beal MF, Moore MA, Studer L. 2003. Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice. Nat Biotechnol 21: 1200-1207.
5. Ben-Hur T, Idelson M, Khaner H, Pera M, Reinhartz E, Itzik A, Reubinoff BE. 2004. Transplantation of human embryonic stem cell-derived neural progenitors improves behavioral deficit in Parkinsonian rats. Stem Cell 22: 1246-1255.
6. Bershadsky A, Kozlov M, Geiger B. 2006. Adhesion-mediated mechanosensitivity: A time to experiment, and a time to theorize. Curr Opin Cell Biol 18: 472-481.
7. Bibel M, Richter J, Schrenk K, Tucker KL, Staiger V, Korte M, Goetz M, Barde YA. 2004. Differentiation of mouse embryonic stem cells into a defined neuronal lineage. Nat Neurosci 7: 1003-1009.
8. Björklund A, Lindvall O. 2000. Cell replacement therapies for central nervous system disorders. Nat Neurosci 3: 537-544.
9. Bjorklund LM, Sanchez-Pernaute R, Chung S, Andersson T, Chen IY, McNaught KS, Brownell AL, Jenkins BG, Wahlestedt C, Kim KS, Isacson O. 2002. Embryonic stem cells develop into functional dopaminergic neurons after transplantation in a Parkinson rat model. Proc Natl Acad Sci USA 99: 2344-2349.
10. Bodas DS, Ken-Malek C. 2007. Fabrication of long-term hydrophilic surfaces of poly(dimethyl siloxane) using 2-hydroxy ethyl methacrylate. Sensor Actuator B 120: 719-723.
11. Chai C, Leong WK. 2007. Biomaterials approach to expand and direct differentiation of stem. Cells Mol Ther 15: 467-480.
12. Christopherson GT, Song H, Mao HQ. 2009. The influence of fiber diameter of electrospun substrates on neural stem cell differentiation and proliferation. Biomaterials 30: 556-564.
13. Discher DE, Janmey P, Wang L. 2005. Tissue cells feel and respond to the stiffness of their substrate. Science 310: 1139-1143.
14. Dowell-Mesfin NM, Abdul-Karim M-A, Turner AMP, Schanz S, Craighead HG, Roysam B, Turner JN, Shain W. 2004. Topographically modified surfaces affect orientation and growth of hippocampal Neurons. J. Neural Eng 1: 78-90.
15. Engler AJ, Sen S, Sweeney HL, Discher DE. 2006. Matrix elasticity direct stem cells lineage specification. Cell 126: 677-689.
16. Erdö F, Bührle C, Blunk J, Hoehn M, Xia Y, Fleischmann B, Föcking M, Küstermann E, Kolossov E, Hescheler J, Hossmann KA, Trapp T. 2003. Host-dependent tumorigenesis of embryonic stem cell transplantation in experimental stroke. J Cereb Blood Flow Metab 23: 780-785.
17. Flanagan LA, Ju YE, Marg B, Osterfield M, Janmey PA. 2002. Neurite branching on deformable substrates. Neuroreport 13: 2411-2415.
18. Frey MT, Tsai IY, Russell TP, Hanks SK, Wang YL. 2006. Cellular responses to substrate topography: Role of myosin II and focal adhesion kinase. Biophys J 15: 3774-3782.
19. Geiger B, Spatz JP, Bershadsky AD. 2009. Environmental sensing through focal adhesions. Nat Rev Mol Cell Biol 10: 21-33.
20. Gerecht S, Bettinger CJ, Zhang Z, Borenstein J, Vunjak-Novakovic G, Langer R. 2007. The effect of actin disrupting agents on contact guidance of human embryonic stem cells. Biomaterials 28: 4068-4077.
21. Guilak F, Cohen DM, Estes BT, Gimble JM, Liedtke W, Chen CS. 2009. Control of stem cell fate by physical interactions with the extracellular matrix. Cell Stem Cell 5: 17-26.
22. Johnston RJ Jr, Desplan C. 2008. Stochastic neuronal cell fate choices. Curr Opin Neurobiol 18: 20-27.
23. Kawasaki H, Mizuseki K, Nishikawa S, Kaneko S, Kuwana Y, Nakanishi S, Nishikawa SI, Sasai Y. 2000. Induction of midbrain dopaminergic neurons from ES cells by stromal cell-derived inducing activity. Neuron 28: 31-40.
24. Kim JH, Auerbach JM, Rodriguez-Gomez JA, Velasco I, Gavin D, Lumelsky N, Lee SH, Nguyen J, Sanchez-Pernaute R, Bankiewicz K, McKay R. 2002. Dopamine neurons derived from embryonic stem cells function in an animal model of Parkinson's disease. Nature 418: 50-56.
25. Lee RM, Kwon KW, Jung H, Kim HN, Suh KY, Kim K, Kim KS. 2010. Direct differentiation of human embryonic stem cells into selective neurons on nanoscale ridge/groove pattern arrays. Biomaterials 31: 4360-4366.
26. Lee SH, Lumelsky N, Studer L, Auerbach IM, McKay RDG. 2000. Efficient generation of midbrain and hindbrain neurons from mouse embryonic stem cells. Nat Biotechnol 18: 675-679.
27. Lu YB, Franze K, Seifert G, Steinhäuser C, Kirchhoff F, Wolburg H, Guck J, Janmey P, Wei EQ, Käs J, Reichenbach A. 2006. Viscoelastic properties of individual glial cells and neurons in the CNS. PNAS 103: 17759-17764.
28. Markert LDA, Lovmand J, Foss M, Lauridsen RH, Lovmand M, Füchtbauer EM, Füchtbauer A, Wertz K, Besenbacher F. 2009. Identification of distinct topographical surface microstructures favoring either undifferentiated expansion or differentiation of murine embryonic stem cells. Stem Cell Dev 18: 1331-1342.
29. Miyamoto Y, Yamauchi J, Chan JR, Okada A, Tomooka Y, Hisanaga S, Tanoue A. 2007. Cdk5 regulates differentiation of oligodendrocyte precursor cells through the direct phosphorylation of paxillin. J Cell Sci 120: 4355-4366.
30. Mokrý J, Nemecek S. 1998. Angiogenesis of extra- and intraembryonic blood vessels is associated with expression of nestin in endothelial cells. Folia Biol 44: 155.
31. Molcanyi M, Riess P, Haj-Yasein NN, Bentz K, Loehr M, Kuchta J, Zivcak J, Stenzel W, Miletic H, Hescheler J, Neugebauer E, Hampl JA, Ernestus RI, Schafer U. 2009. Developmental potential of the murine embryonic stem cells transplanted into the healthy rat brain-novel insights into tumorigenesis. Cell Physiol Biochem 24: 87-894.
32. Mruthyunjaya S, Manchanda R, Godbole R, Pujari R, Shiras A. 2010. Laminin-1 induces neurite outgrowth in human mesenchymal stem cells in serum/differentiation factors-free conditions through activation of FAK-MEK/ERK signaling pathways. Biochem Biophys Res Commun 391: 43-48.
33. Nagata I, Kawana A, Nakatsuji N. 1993. Perpendicular contact guidance of CNS neuroblasts on artificial microstructures. Development 117: 401-408.
34. Parekkadan B, Berdichevsky Y, Irimia D, Leeder A, Yarmush G, Toner M, Levine JB, Yarmush ML. 2008. Cell-cell interaction modulates neuroectodermal specification of embryonic stem cells. Neurosci Lett 438: 190-195.
35. Pelham RJ, Wang YL. 1997. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc Natl Acad Sci USA 94: 13661-13665.
36. Rajnicek AM, McCaig CD. 1997. Guidance of CNS growth cones by substratum grooves and ridges: Effects of inhibitors of the cytoskeleton, calcium channels and signal transduction pathways. J Cell Sci 110: 2915-2924.
37. Schoen I, Hu W, Klotzsch E, Vogel V. 2010. Probing Cellualr traction forces by micropillar arrays: Contribution of substrate warping to pillar deflection. Nano Lett 12: 1823-1830.
38. Stavridis MP, Collins BJ, Storey KG. 2010. Retinoic acid orchestrates fibroblast growth factor signalling to drive embryonic stem cell differentiation. Development 137: 881-890.
39. Thomson JA, Itskovitz-Eldor J, Shapiro SS, Waknitz MA, Swiergiel JJ, Marshall VS, Jones JM. 1998. Embryonic stem cell lines derived from human blastocysts. Science 282: 1145-1147.
40. Timpl R. 1996. Macromolecular organization of basement membranes. Curr Opin Cell Biol 8: 618-624.
41. Wang JZ, Liu F. 2008. Microtubule-associated protein tau in development, degeneration and protection of neurons. Prog Neurobiol 85: 148-175.
42. Yang JR, Liao CH, Pang CY, Huang LL, Lin YT, Chen YL, Shiue YL, Chen LR. 2010. Directed differentiation into neural lineages and therapeutic potential of porcine embryonic stem cells in rat Parkinson's disease model. Cell Reprogram 12: 447-461.
43. Yim EKF, Darling EM, Kulangara K, Guilak F, Leong KW. 2010. Nanotopography-induced changes in focal adhesion, cytoskeletal organization and mechanical properties of human mesenchymal stem cells. Biomaterials 31: 1299-1306.
44. Yim EKF, Pang SW, Lenog KW. 2007. Synthetic nanostructures inducing differentiation of human mesenchymal stem cells into neuronal lineage. Exp Cell Res 313: 1820-1829.
45. Ying QL, Stavridis M, Griffiths D, Li M, Smith A. 2003. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol 21: 183-186.