New synthesis of 6[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid and evaluation of the influence of adamantyl group on the DNA binding of a naphthoic retinoid

Bioorganic Chemistry

Volumn 39, Issue 4, 2011, Pages 151-158

  Milanese, Alberto ^a   Gorincioi, Elena ^b,c   Rajabi, Mehdi ^d   Vistoli, Giulio ^b   Santaniello, Enzo ^b  

^a Foundation for Research in Life Sciences C/o Insubrias Park   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c Institutul de Chimie Al Academiei de Tiinte a Moldovei ^*  (Moldova)

^d ISLAMIC AZAD UNIVERSITY   (Iran)

Author keywords

6 3 (1 Adamantyl) 4 methoxyphenyl 2 naphthoic acid; DNA intercalative binding; Hydrophobic interactions; Naphthoic retinoids; Suzuki coupling

Indexed keywords

4 METHOXYPHENYL BORONIC ACID; 6 (4 METHOXYPHENYL) 2 NAPHTHOIC ACID; 6 BROMO 2 NAPHTHOIC ACID; ADAPALENE; ANTHRACYCLINE; AROMATIC CARBOXYLIC ACID; ETHYL 6 (4 METHOXYPHENYL) 2 NAPHTHOATE; ETHYL 6 [(3 ADAMANTYL 4 METHOXYPHENYL)] 2 NAPHTHOATE; RETINOIC ACID RECEPTOR BETA; RETINOIC ACID RECEPTOR GAMMA; RETINOID DERIVATIVE; UNCLASSIFIED DRUG;

AQUEOUS SOLUTION; ARTICLE; COMPLEX FORMATION; DRUG DNA BINDING; DRUG SYNTHESIS; HYDROPHOBICITY; MOLECULAR MODEL; PRIORITY JOURNAL; SUZUKI REACTION; ULTRAVIOLET SPECTROSCOPY;

ADAMANTANE; CATALYSIS; DNA; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KINETICS; LEAD; MODELS, MOLECULAR; NAPHTHALENES; RECEPTORS, RETINOIC ACID; RETINOIDS; SPECTROPHOTOMETRY, ULTRAVIOLET;

EID: 80053052661     PISSN: 00452068     EISSN: 10902120     Source Type: Journal    
DOI: 10.1016/j.bioorg.2011.07.003     Document Type: Article

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