Effects of mitochondrial mutations on hearing and cochlear pathology with age

Hearing Research

Volumn 280, Issue 1-2, 2011, Pages 201-208

  Crawley, Brianna K ^a   Keithley, Elizabeth M ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; DNA DIRECTED DNA POLYMERASE GAMMA; MITOCHONDRIAL DNA;

AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUDITORY THRESHOLD SHIFT; CELL LOSS; CELL SURVIVAL; CONTROLLED STUDY; DISTORTION PRODUCT OTOACOUSTIC EMISSION; DNA DAMAGE; ENZYME ACTIVITY; EVOKED BRAIN STEM AUDITORY RESPONSE; FEMALE; GENE DELETION; GENE MUTATION; GENETIC CODE; HEARING LOSS; HEARING TEST; HETEROZYGOTE; HISTOPATHOLOGY; INNER EAR DISEASE; LOSS OF FUNCTION MUTATION; LOW FREQUENCY NOISE; MALE; MITOCHONDRIAL ENERGY TRANSFER; MOUSE; MUTATIONAL ANALYSIS; NOISE INJURY; NONHUMAN; PREMATURE AGING; PRIORITY JOURNAL; WILD TYPE;

AGING; ANIMALS; COCHLEA; DNA, MITOCHONDRIAL; DNA-DIRECTED DNA POLYMERASE; ELECTRON TRANSPORT COMPLEX IV; FEMALE; HEARING; MALE; MICE; MICE, TRANSGENIC; MODELS, ANIMAL; MUTATION; PRESBYCUSIS; SPIRAL GANGLION;

EID: 80053052539     PISSN: 03785955     EISSN: 18785891     Source Type: Journal    
DOI: 10.1016/j.heares.2011.05.015     Document Type: Article

References (30)

1. Ames B.N. Delaying the mitochondrial decay of aging. Ann. N. Y Acad. Sci. 2004, 1019:406-411.
2. Bai U., Seidman M.D., Hinojosa R., Quirk W.S. Mitochondrial DNA deletions associated with aging and possibly presbycusis: a human archival temporal bone study. Am. J. Otol. 1997, 18:449-453.
3. Bailey L.J., Cluett T.J., Reyes A., Prolla T.A., Poulton J., Leeuwenburgh C., Holt I.J. Mice expressing an error-prone DNA polymerase in mitochondria display elevated replication pausing and chromosomal breakage at fragile sites of mitochondrial DNA. Nucleic Acids Res. 2009, 37:2327-2335.
4. Bielefeld E.C., Hu B.H., Harris K.C., Henderson D. Damage and threshold shift resulting from cochlear exposure to paraquat-generated superoxide. Hear Res. 2005, 207:35-42.
5. Edgar D., Shabalina I., Camara Y., Wredenberg A., Calvaruso M.A., Nijtmans L., Nedergaard J., Cannon B., Larsson N.G., Trifunovic A. Random point mutations with major effects on protein-coding genes are the driving force behind premature aging in mtDNA mutator mice. Cell Metab. 2009, 10:131-138.
6. Fischel-Ghodsian N., Bykhovskaya Y., Taylor K., Kahen T., Cantor R., Ehrenman K., Smith R., Keithley E. Temporal bone analysis of patients with presbycusis reveals high frequency of mitochondrial mutations. Hear Res. 1997, 110:147-154.
7. Gates G.A., Mills J.H. Presbycusis. Lancet 2005, 366:1111-1120.
8. Hübscher U., Kuenzle C.C., Spadari S. Functional roles of DNA polymerases beta and gamma. Proc. Natl. Acad. Sci. U S A 1979, 76:2316-2320.
9. Keithley E.M., Canto C., Zheng Q.Y., Fischel-Ghodsian N., Johnson K.R. Age-related hearing loss and the ahl locus in mice. Hear Res. 2004, 188:21-28.
10. Kujoth G.C., Hiona A., Pugh T.D., Someya S., Panzer K., Wohlgemuth S.E., Hofer T., Seo A.Y., Sullivan R., Jobling W.A., Morrrow J.D., Van Remmen H., Sedivy J.M., Yamasoba T., Tanokura M., Weindruch R., Leeuwenburgh C., Prolla T.A. Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging. Science 2005, 309:481-484.
11. Kujoth G.C., Prolla T.A. Evolving insight into the role of mitochondrial DNA mutations in aging. Exp. Gerontol. 2008, 43:20-23.
12. Le Prell C.G., Yamashita D., Minami S.B., Yamasoba T., Miller J.M. Mechanisms of noise-induced hearing loss indicate multiple methods of prevention. Hear Res. 2007, 226:22-43.
13. Lin C.Y., Wu J.L., Shih T.S., Tsai P.J., Sun Y.M., Guo Y.L. Glutathione S-transferase M1, T1, and P1 polymorphisms as susceptibility factors for noise-induced temporary threshold shift. Hear Res. 2009, 257:8-15.
14. Mikaelian D.O., Warfield D., Norris O. Genetic progressive hearing loss in the C57-b16 mouse. Relation of behavioral responses to cochlear anatomy. Acta Otolaryngol. 1974, 77:327-334.
15. Niu X., Trifunovic A., Larsson N.-G., Canlon B. Somatic mtDNA mutations cause progressive hearing loss in the mouse. Exp. Cell Res. 2007, 313:3924-3934.
16. Noben-Trauth K., Zheng Q.Y., Johnson K.R. Association of cadherin 23 with polygenic inheritance and genetic modification of sensorineural hearing loss. Nat. Genet. 2003, 35:21-23.
17. Ryan A.F., Watts A.G. Expression of mRNAs encoding alpha and beta subunit isoforms of the Na, K-ATPase in the rat cochlea. Mol Cell Neurosci. 1991, 2:179-187.
18. Schuknecht H.F., Gacek M.R. Cochlear pathology in presbycusis. Ann. Otol. Rhinol. Laryngol. 1993, 102:1-16.
19. Seidman M.D., Ahmad N., Joshi D., Seidman J., Thawani S., Quirk W.S. Age-related hearing loss and its association with reactive oxygen species and mitochondrial DNA damage. Acta Otolryngol. 2004, 552:16-24.
20. Someya S., Yamasoba T., Kujoth G.C., Pugh T.D., Weindruch R., Tanokura M., Prolla T.A. The role of mtDNA mutations in the pathogenesis of age-related hearing loss in mice carrying a mutator DNA polymerase-γ. Neurobiol. Aging 2008, 29:1080-1092.
21. Trifunovic A., Hansson A., Wredenberg A., Rovio A.T., Dufour E., Khvorostov I., Spelbrink J.N., Wibom R., Jacobs H.T., Larsson N.G. Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production. Proc. Natl. Acad. Sci. U S A 2005, 102:17993-17998.
22. Trifunovic A., Wredenberg A., Falkenberg M., Spelbrink J.N., Rovio A.T., Bruder C.E., Bohlooly Y., Gidlof S., Oldfors A., Wibom R., Tornell J., Jacobs H.T., Larsson N. Premature aging in mice expressing defective mitochondrial DNA polymerase. Nature 2004, 429:417-422.
23. Vermulst M., Wanagat J., Kujoth G.C., Bielas J.H., Rabinovitch P.S., Prolla T.A., Loeb L.A. DNA deletions and clonal mutations drive premature aging in mitochondrial mutator mice. Nat. Genet. 2008, 40:392-394.
24. Vermulst M., Wanagat J., Loeb L.A. On mitochondria, mutations, and methodology. Cell Metab. 2009, 10:437.
25. Vlajkovic S.M., Housley G.D., Thorne P.R. Adenosine and the auditory system. Curr. Neuropharmacol. 2009, 7:246-256.
26. Wang Y., Hirose K., Liberman M.C. Dynamics of noise-induced cellular injury and repair in the mouse cochlea. J. Assoc. Res. Otolaryngol. 2002, 3:248-268.
27. Webster D.B. The spiral ganglion and cochlear nuclei of deafness mice. Hear Res. 1985, 18:19-27.
28. Wong-Riley M. Changes in the visual system of monocularly sutured or enucleated cats demonstrable with cytochrome oxidase histochemistry. Brain Res. 1979, 171:11-28.
29. Yamasoba T., Pourbakht A., Sakamoto T., Suzuki M. Ebselen prevents noise-induced excitotoxicity and temporary threshold shift. Neurosci. Lett. 2005, 380:234-238.
30. Yamasoba T., Someya S., Yamada C., Weindruch R., Prolla T.A., Tanokura M. Role of mitochondrial dysfunction and mitochondrial DNA mutations in age-related hearing loss. Hear Res. 2007, 226:185-193.