Enhanced toxicity of the protein cross-linkers divinyl sulfone and diethyl acetylenedicarboxylate in comparison to related monofunctional electrophiles

Chemical Research in Toxicology

Volumn 24, Issue 9, 2011, Pages 1457-1459

  West, James D ^a   Stamm, Chelsea E ^a   Brown, Haley A ^a   Justice, Samantha L ^a   Morano, Kevin A ^b  

^a 931 College Mall   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; DIETHYLACETYLENEDICARBOXYLATE; DIVINYL SULFONE; ELECTROPHILE; ETHYLVINYLSULFONE; SULFONE DERIVATIVE; THIOREDOXIN 2; UNCLASSIFIED DRUG;

ARTICLE; CARCINOMA CELL; COLORECTAL CARCINOMA; CYTOTOXICITY; HUMAN; IN VITRO STUDY; NONHUMAN; PROTEIN CROSS LINKING; SACCHAROMYCES CEREVISIAE;

ALKYLATION; ALKYNES; CELL LINE, TUMOR; CROSS-LINKING REAGENTS; CYTOTOXINS; HUMANS; PROTEINS; SACCHAROMYCES CEREVISIAE; SULFONES;

SACCHAROMYCES CEREVISIAE;

EID: 80053014926     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx200302w     Document Type: Article

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