-
1
-
-
34547216747
-
Genetic variants regulating ormdl3 expression contribute to the risk of childhood asthma
-
Moffatt M.F., Kabesch M., Liang L., Dixon A.L., Strachan D., Heath S., et al. Genetic variants regulating ormdl3 expression contribute to the risk of childhood asthma. Nature 2007, 448:470-473.
-
(2007)
Nature
, vol.448
, pp. 470-473
-
-
Moffatt, M.F.1
Kabesch, M.2
Liang, L.3
Dixon, A.L.4
Strachan, D.5
Heath, S.6
-
2
-
-
69449101386
-
Allele-specific chromatin remodeling in the zpbp2/gsdmb/ormdl3 locus associated with the risk of asthma and autoimmune disease
-
Verlaan D.J., Berlivet S., Hunninghake G.M., Madore A.M., Larivière M., Moussette S., et al. Allele-specific chromatin remodeling in the zpbp2/gsdmb/ormdl3 locus associated with the risk of asthma and autoimmune disease. Am J Hum Genet 2009, 85:377-393.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 377-393
-
-
Verlaan, D.J.1
Berlivet, S.2
Hunninghake, G.M.3
Madore, A.M.4
Larivière, M.5
Moussette, S.6
-
3
-
-
57349101088
-
Effect of 17q21 variants and smoking exposure in early-onset asthma
-
Bouzigon E., Corda E., Aschard H., Dizier M.H., Boland A., Bousquet J., et al. Effect of 17q21 variants and smoking exposure in early-onset asthma. N Engl J Med 2008, 359:1985-1994.
-
(2008)
N Engl J Med
, vol.359
, pp. 1985-1994
-
-
Bouzigon, E.1
Corda, E.2
Aschard, H.3
Dizier, M.H.4
Boland, A.5
Bousquet, J.6
-
4
-
-
0036046814
-
ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins
-
RESEARCH0027
-
Hjelmqvist L., Tuson M., Marfany G., Herrero E., Balcells S., Gonzàlez-Duarte R. ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins. Genome Biol 2002, 3. RESEARCH0027.
-
(2002)
Genome Biol
, vol.3
-
-
Hjelmqvist, L.1
Tuson, M.2
Marfany, G.3
Herrero, E.4
Balcells, S.5
Gonzàlez-Duarte, R.6
-
5
-
-
77649150074
-
The asthma-associated ormdl3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress
-
Cantero-Recasens G., Fandos C., Rubio-Moscardo F., Valverde M.A., Vicente R. The asthma-associated ormdl3 gene product regulates endoplasmic reticulum-mediated calcium signaling and cellular stress. Hum Mol Genet 2010, 19:111-121.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 111-121
-
-
Cantero-Recasens, G.1
Fandos, C.2
Rubio-Moscardo, F.3
Valverde, M.A.4
Vicente, R.5
-
6
-
-
48349136889
-
Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett J.C., Hansoul S., Nicolae D.L., Cho J.H., Duerr R.H., Rioux J.D., et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 2008, 40:955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
Cho, J.H.4
Duerr, R.H.5
Rioux, J.D.6
-
7
-
-
77649121162
-
Orm family proteins mediate sphingolipid homeostasis
-
Breslow D.K., Collins S.R., Bodenmiller B., Aebersold R., Simons K., Shevchenko A., et al. Orm family proteins mediate sphingolipid homeostasis. Nature 2010, 463:1048-1053.
-
(2010)
Nature
, vol.463
, pp. 1048-1053
-
-
Breslow, D.K.1
Collins, S.R.2
Bodenmiller, B.3
Aebersold, R.4
Simons, K.5
Shevchenko, A.6
-
8
-
-
42949118737
-
Cigarette smoke induces an unfolded protein response in the human lung: A proteomic approach
-
Kelsen S.G., Duan X., Ji R., Perez O., Liu C., Merali S. Cigarette smoke induces an unfolded protein response in the human lung: A proteomic approach. Am J Respir Cell Mol Biol 2008, 38:541-550.
-
(2008)
Am J Respir Cell Mol Biol
, vol.38
, pp. 541-550
-
-
Kelsen, S.G.1
Duan, X.2
Ji, R.3
Perez, O.4
Liu, C.5
Merali, S.6
-
9
-
-
44449150336
-
Ormdl3 gene is associated with asthma in three ethnically diverse populations
-
Galanter J., Choudhry S., Eng C., Nazario S., Rodríguez-Santana J.R., Casal J., et al. Ormdl3 gene is associated with asthma in three ethnically diverse populations. Am J Respir Crit Care Med 2008, 177:1194-1200.
-
(2008)
Am J Respir Crit Care Med
, vol.177
, pp. 1194-1200
-
-
Galanter, J.1
Choudhry, S.2
Eng, C.3
Nazario, S.4
Rodríguez-Santana, J.R.5
Casal, J.6
-
10
-
-
69349084304
-
17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry
-
Flory J.H., Sleiman P.M., Christie J.D., Annaiah K., Bradfield J., Kim C.E., et al. 17q12-21 variants interact with smoke exposure as a risk factor for pediatric asthma but are equally associated with early-onset versus late-onset asthma in North Americans of European ancestry. J Allergy Clin Immunol 2009, 124:605-607.
-
(2009)
J Allergy Clin Immunol
, vol.124
, pp. 605-607
-
-
Flory, J.H.1
Sleiman, P.M.2
Christie, J.D.3
Annaiah, K.4
Bradfield, J.5
Kim, C.E.6
-
11
-
-
62449117832
-
Asthma and atopy are associated with chromosome 17q21 markers in Chinese children
-
Leung T.F., Sy H.Y., Ng M.C., Chan I.H., Wong G.W., Tang N.L., et al. Asthma and atopy are associated with chromosome 17q21 markers in Chinese children. Allergy 2009, 64:621-628.
-
(2009)
Allergy
, vol.64
, pp. 621-628
-
-
Leung, T.F.1
Sy, H.Y.2
Ng, M.C.3
Chan, I.H.4
Wong, G.W.5
Tang, N.L.6
-
12
-
-
62449114842
-
Genetic variation in orm1-like 3 (ormdl3) and gasdermin-like (gsdml) and childhood asthma
-
Wu H., Romieu I., Sienra-Monge J.J., Li H., del Rio-Navarro B.E., London S.J. Genetic variation in orm1-like 3 (ormdl3) and gasdermin-like (gsdml) and childhood asthma. Allergy 2009, 64:629-635.
-
(2009)
Allergy
, vol.64
, pp. 629-635
-
-
Wu, H.1
Romieu, I.2
Sienra-Monge, J.J.3
Li, H.4
del Rio-Navarro, B.E.5
London, S.J.6
-
13
-
-
38949188741
-
Replication of an association between 17q21 snps and asthma in a French-Canadian familial collection
-
Madore A.M., Tremblay K., Hudson T.J., Laprise C. Replication of an association between 17q21 snps and asthma in a French-Canadian familial collection. Hum Genet 2008, 123:93-95.
-
(2008)
Hum Genet
, vol.123
, pp. 93-95
-
-
Madore, A.M.1
Tremblay, K.2
Hudson, T.J.3
Laprise, C.4
-
14
-
-
57149129440
-
Ormdl3 variants associated with asthma susceptibility in North Americans of European ancestry
-
Sleiman P.M., Annaiah K., Imielinski M., Bradfield J.P., Kim C.E., Frackelton E.C., et al. Ormdl3 variants associated with asthma susceptibility in North Americans of European ancestry. J Allergy Clin Immunol 2008, 122:1225-1227.
-
(2008)
J Allergy Clin Immunol
, vol.122
, pp. 1225-1227
-
-
Sleiman, P.M.1
Annaiah, K.2
Imielinski, M.3
Bradfield, J.P.4
Kim, C.E.5
Frackelton, E.C.6
-
15
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt M.F., Gut I.G., Demenais F., Strachan D.P., Bouzigon E., Health S., et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010, 363:1211-1221.
-
(2010)
N Engl J Med
, vol.363
, pp. 1211-1221
-
-
Moffatt, M.F.1
Gut, I.G.2
Demenais, F.3
Strachan, D.P.4
Bouzigon, E.5
Health, S.6
-
16
-
-
0018081327
-
Epidemiology standardization project
-
Ferris B.G. Epidemiology standardization project. Am Rev Respir Dis 1978, 118(Suppl):1-88.
-
(1978)
Am Rev Respir Dis
, vol.118
, Issue.SUPPL.
, pp. 1-88
-
-
Ferris, B.G.1
-
17
-
-
24644496531
-
Interpretative strategies for lung function tests
-
Pellegrino R., Viegi G., Brusasco V., Crapo R.O., Burgos F., Casaburi R., et al. Interpretative strategies for lung function tests. Eur Respir J 2005, 26:948-968.
-
(2005)
Eur Respir J
, vol.26
, pp. 948-968
-
-
Pellegrino, R.1
Viegi, G.2
Brusasco, V.3
Crapo, R.O.4
Burgos, F.5
Casaburi, R.6
-
18
-
-
21744460289
-
Standardisation of spirometry
-
Miller M.R., Hankinson J., Brusasco V., Burgos F., Casaburi R., Coates A., et al. Standardisation of spirometry. Eur Respir J 2005, 26:319-338.
-
(2005)
Eur Respir J
, vol.26
, pp. 319-338
-
-
Miller, M.R.1
Hankinson, J.2
Brusasco, V.3
Burgos, F.4
Casaburi, R.5
Coates, A.6
-
19
-
-
80052968676
-
-
Global Strategy for Asthma Management and Prevention. Global initiative for asthma. NIH Publication no. 01-3659. NHLBI/WHO2002.
-
Global Strategy for Asthma Management and Prevention. Global initiative for asthma. NIH Publication no. 01-3659. NHLBI/WHO2002.
-
-
-
-
20
-
-
0002885825
-
Allergic rhinitis and its impact on asthma
-
Aria Workshop Group, World Health Organization
-
Bousquet J., Van Cauwenberge P., Khaltaev N. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol 2001, 108:S147-S334. Aria Workshop Group, World Health Organization.
-
(2001)
J Allergy Clin Immunol
, vol.108
-
-
Bousquet, J.1
Van Cauwenberge, P.2
Khaltaev, N.3
-
21
-
-
0001779228
-
Diagnostic features of atopic dermatitis
-
Hanifin J.M., Rajka G. Diagnostic features of atopic dermatitis. Acta Derm Venereol 1980, 92:44-47.
-
(1980)
Acta Derm Venereol
, vol.92
, pp. 44-47
-
-
Hanifin, J.M.1
Rajka, G.2
-
22
-
-
0036428488
-
Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population
-
Bucková D., Hollá L.I., Vasku A., Znojil V., Vácha J. Lack of association between atopic asthma and the tumor necrosis factor alpha-308 gene polymorphism in a Czech population. J Investig Allergol Clin Immunol 2002, 12:192-197.
-
(2002)
J Investig Allergol Clin Immunol
, vol.12
, pp. 192-197
-
-
Bucková, D.1
Hollá, L.I.2
Vasku, A.3
Znojil, V.4
Vácha, J.5
-
23
-
-
0036340211
-
Statistics review 4: Sample size calculations
-
Whitley E., Ball J. Statistics review 4: Sample size calculations. Crit Care 2002, 6:335-341.
-
(2002)
Crit Care
, vol.6
, pp. 335-341
-
-
Whitley, E.1
Ball, J.2
-
25
-
-
77954651403
-
17q21 variants modify the association between early respiratory infections and asthma
-
Smit L.A., Bouzigon E., Pin I., Siroux V., Monier F., Aschard H., et al. 17q21 variants modify the association between early respiratory infections and asthma. Eur Respir J 2010, 36:57-64.
-
(2010)
Eur Respir J
, vol.36
, pp. 57-64
-
-
Smit, L.A.1
Bouzigon, E.2
Pin, I.3
Siroux, V.4
Monier, F.5
Aschard, H.6
-
26
-
-
77954957118
-
A sequence variant on 17q21 is associated with age at onset and severity of asthma
-
Halapi E., Gudbjartsson D.F., Jonsdottir G.M., Bjornsdottir U.S., Thorleifsson G., Helgadottir H., et al. A sequence variant on 17q21 is associated with age at onset and severity of asthma. Eur J Hum Genet 2010, 18:902-908.
-
(2010)
Eur J Hum Genet
, vol.18
, pp. 902-908
-
-
Halapi, E.1
Gudbjartsson, D.F.2
Jonsdottir, G.M.3
Bjornsdottir, U.S.4
Thorleifsson, G.5
Helgadottir, H.6
-
27
-
-
79251648866
-
Chromosome 17q21 SNP and severe asthma
-
Binia A., Khorasani N., Bhaysar P.K., Adcock I., Brightling C.E., Chung K.F., et al. Chromosome 17q21 SNP and severe asthma. J Hum Genet 2011, 56:97-98.
-
(2011)
J Hum Genet
, vol.56
, pp. 97-98
-
-
Binia, A.1
Khorasani, N.2
Bhaysar, P.K.3
Adcock, I.4
Brightling, C.E.5
Chung, K.F.6
-
28
-
-
79952745551
-
Association between ORMDL3, IL1R1 and a deletion on chromosome 17q21 with asthma risk in Australia
-
Ferreira M.A., McRae A.F., Medland S.E., Nyholt D.R., Gordon S.D., Wright M.J., et al. Association between ORMDL3, IL1R1 and a deletion on chromosome 17q21 with asthma risk in Australia. Eur J Hum Genet 2011, 19:458-464.
-
(2011)
Eur J Hum Genet
, vol.19
, pp. 458-464
-
-
Ferreira, M.A.1
McRae, A.F.2
Medland, S.E.3
Nyholt, D.R.4
Gordon, S.D.5
Wright, M.J.6
-
29
-
-
61449154539
-
Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood
-
Bisgaard H., Bønnelykke K., Sleiman P.M., Brasholt M., Chawes B., Kreiner-Møller E., et al. Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood. Am J Respir Crit Care Med 2009, 1749:179-185.
-
(2009)
Am J Respir Crit Care Med
, vol.1749
, pp. 179-185
-
-
Bisgaard, H.1
Bønnelykke, K.2
Sleiman, P.M.3
Brasholt, M.4
Chawes, B.5
Kreiner-Møller, E.6
-
30
-
-
41549111983
-
A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications
-
Tavendale R., Macgregor D.F., Mukhopadhyay S., Palmer C.N. A polymorphism controlling ORMDL3 expression is associated with asthma that is poorly controlled by current medications. J Allergy Clin Immunol 2008, 121:860-863.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 860-863
-
-
Tavendale, R.1
Macgregor, D.F.2
Mukhopadhyay, S.3
Palmer, C.N.4
-
31
-
-
0028329080
-
Crystal structure of transcription factor e47: E-box recognition by a basic region helix-loop-helix dimer
-
Ellenberger T., Fass D., Arnaud M., Harrison S.C. Crystal structure of transcription factor e47: E-box recognition by a basic region helix-loop-helix dimer. Genes Dev 1994, 8:970-980.
-
(1994)
Genes Dev
, vol.8
, pp. 970-980
-
-
Ellenberger, T.1
Fass, D.2
Arnaud, M.3
Harrison, S.C.4
-
32
-
-
0031860393
-
Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL
-
Heinemeyer T., Wingender E., Reuter I., Hermjakob H., Kel A.E., Kel O.V., et al. Databases on transcriptional regulation: TRANSFAC, TRRD and COMPEL. Nucleic Acids Res 1998, 26:362-367.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 362-367
-
-
Heinemeyer, T.1
Wingender, E.2
Reuter, I.3
Hermjakob, H.4
Kel, A.E.5
Kel, O.V.6
-
33
-
-
27544442994
-
Helix-loop-helix proteins and lymphocyte development
-
Murre C. Helix-loop-helix proteins and lymphocyte development. Nat Immunol 2005, 6:1079-1086.
-
(2005)
Nat Immunol
, vol.6
, pp. 1079-1086
-
-
Murre, C.1
-
35
-
-
80052969121
-
Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL
-
1587. 1594
-
Lluis A., Schedel M., Liu J., Illi S., Depner M., von Mutius E., et al. Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL. J Allergy Clin Immunol 2011, 17:127. 1587. 1594.
-
(2011)
J Allergy Clin Immunol
, vol.17
, pp. 127
-
-
Lluis, A.1
Schedel, M.2
Liu, J.3
Illi, S.4
Depner, M.5
von Mutius, E.6
|