Cryptic AUG is important for 48S ribosomal assembly during internal initiation of translation of coxsackievirus B3 RNA

Journal of General Virology

Volumn 92, Issue 10, 2011, Pages 2310-2319

  Verma, Bhupendra ^a   Ponnuswamy, Anand ^a   Gnanasundram, Sivakumar Vadivel ^a   Das, Saumitra ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; VIRUS RNA;

ARTICLE; COXSACKIE VIRUS B3; GENE SILENCING; NONHUMAN; PRIORITY JOURNAL; RNA STRUCTURE; TRANSLATION INITIATION; UNTRANSLATED REGION; VIRAL GENETICS; VIRUS MUTANT;

5' UNTRANSLATED REGIONS; CODON, INITIATOR; ENTEROVIRUS B, HUMAN; HUMANS; MUTAGENESIS, SITE-DIRECTED; NUCLEIC ACID CONFORMATION; PEPTIDE CHAIN INITIATION, TRANSLATIONAL; RNA, VIRAL; VIRAL PROTEINS;

COXSACKIEVIRUS;

EID: 80052931005     PISSN: 00221317     EISSN: 14652099     Source Type: Journal    
DOI: 10.1099/vir.0.032151-0     Document Type: Article

References (29)

1. Agol, V. I. (1991). The 59-untranslated region of picornaviral genomes. Adv Virus Res 40, 103-180.
2. Bailey, J. M. & Tapprich, W. E. (2007). Structure of the 59 nontranslated region of the coxsackievirus b3 genome: chemical modification and comparative sequence analysis. J Virol 81, 650-668.
3. Belsham, G. J. & Sonenberg, N. (1996). RNA-protein interactions in regulation of picornavirus RNA translation. Microbiol Rev 60, 499-511.
4. Bhattacharyya, S. & Das, S. (2005). Mapping of secondary structure of the spacer region within the 59-untranslated region of the coxsackievirus B3 RNA: possible role of an apical GAGA loop in binding La protein and influencing internal initiation of translation. Virus Res 108, 89-100.
5. Bhattacharyya, S. & Das, S. (2006). An apical GAGA loop within 59 UTR of the coxsackievirus B3 RNA maintains structural organization of the IRES element required for efficient ribosome entry. RNA Biol 3, 60-68.
6. Bhattacharyya, S., Verma, B., Pandey, G. & Das, S. (2008). The structure and function of a cis-acting element located upstream of the IRES that influences coxsackievirus B3 RNA translation. Virology 377, 345-354.
7. Borman, A. M. & Jackson, R. J. (1992). Initiation of translation of human rhinovirus RNA: mapping the internal ribosome entry site. Virology 188, 685-696.
8. Chen, T. C., Weng, K. F., Chang, S. C., Lin, J. Y., Huang, P. N. & Shih, S. R. (2008). Development of antiviral agents for enteroviruses. J Antimicrob Chemother 62, 1169-1173.
9. Costa-Mattioli, M., Svitkin, Y. & Sonenberg, N. (2004). La autoantigen is necessary for optimal function of the poliovirus and hepatitis C virus internal ribosome entry site in vivo and in vitro. Mol Cell Biol 24, 6861-6870.
10. Dhar, D., Roy, S. & Das, S. (2007). Translational control of the interferon regulatory factor 2 mRNA by IRES element. Nucleic Acids Res 35, 5409-5421.
11. Dmitriev, S. E., Pisarev, A. V., Rubtsova, M. P., Dunaevsky, Y. E. & Shatsky, I. N. (2003). Conversion of 48S translation preinitiation complexes into 80S initiation complexes as revealed by toeprinting. FEBS Lett 533, 99-104.
12. Fitzgerald, K. D. & Semler, B. L. (2009). Bridging IRES elements in mRNAs to the eukaryotic translation apparatus. Biochim Biophys Acta 1789, 518-528.
13. Iizuka, N., Yonekawa, H. & Nomoto, A. (1991). Nucleotide sequences important for translation initiation of enterovirus RNA. J Virol 65, 4867-4873.
14. Jang, S. K., Kraäusslich, H. G., Nicklin, M. J., Duke, G. M., Palmenberg, A. C. & Wimmer, E. (1988). A segment of the 59 nontranslated region of encephalomyocarditis virus RNA directs internal entry of ribosomes during in vitro translation. J Virol 62, 2636-2643.
15. Liu, Z., Carthy, C. M., Cheung, P., Bohunek, L., Wilson, J. E., McManus, B. M. & Yang, D. (1999). Structural and functional analysis of the 59 untranslated region of coxsackievirus B3 RNA: in vivo translational and infectivity studies of full-length mutants. Virology 265, 206-217.
16. Meerovitch, K., Nicholson, R. & Sonenberg, N. (1991). In vitro mutational analysis of cis-acting RNA translational elements within the poliovirus type 2 59 untranslated region. J Virol 65, 5895-5901.
17. M'hadheb-Gharbi, M. B., Paulous, S., Aouni, M., Kean, K. M. & Gharbi, J. (2007). The substitution U475AC with Sabin3-like mutation within the IRES attenuate coxsackievirus B3 cardiovirulence. Mol Biotechnol 36, 52-60.
18. Nicholson, R., Pelletier, J., Le, S. Y. & Sonenberg, N. (1991). Structural and functional analysis of the ribosome landing pad of poliovirus type 2: in vivo translation studies. J Virol 65, 5886-5894.
19. Pelletier, J., Flynn, M. E., Kaplan, G., Racaniello, V. R. & Sonenberg, N. (1988). Mutational analysis of upstream AUG codons of poliovirus RNA. J Virol 62, 4486-4492.
20. Pilipenko, E. V., Gmyl, A. P.,Maslova, S. V., Svitkin, Y. V., Sinyakov, A. N. & Agol, V. I. (1992). Prokaryotic-like cis elements in the cap-independent internal initiation of translation on picornavirus RNA. Cell 68, 119-131.
21. Pöyry, T., Kinnunen, L. & Hovi, T. (1992). Genetic variation in vivo and proposed functional domains of the 59 noncoding region of poliovirus RNA. J Virol 66, 5313-5319.
22. Pudi, R., Srinivasan, P. & Das, S. (2004). La protein binding at the GCAC site near the initiator AUG facilitates the ribosomal assembly on the hepatitis C virus RNA to influence internal ribosome entry site-mediated translation. J Biol Chem 279, 29879-29888.
23. Ray, P. S. & Das, S. (2002). La autoantigen is required for the internal ribosome entry site-mediated translation of coxsackievirus B3 RNA. Nucleic Acids Res 30, 4500-4508.
24. Skinner, M. A., Racaniello, V. R., Dunn, G., Cooper, J., Minor, P. D. & Almond, J. W. (1989). New model for the secondary structure of the 59 non-coding RNA of poliovirus is supported by biochemical and genetic data that also show that RNA secondary structure is important in neurovirulence. J Mol Biol 207, 379-392.
25. Slobodskaya, O. R., Gmyl, A. P., Maslova, S. V., Tolskaya, E. A., Viktorova, E. G. & Agol, V. I. (1996). Poliovirus neurovirulence correlates with the presence of a cryptic AUG upstream of the initiator codon. Virology 221, 141-150.
26. Verma, B., Bhattacharyya, S. & Das, S. (2010). Polypyrimidine tractbinding protein interacts with coxsackievirus B3 RNA and influences its translation. J Gen Virol 91, 1245-1255.
27. Yang, D., Wilson, J. E., Anderson, D. R., Bohunek, L., Cordeiro, C., Kandolf, R. & McManus, B. M. (1997). In vitro mutational and inhibitory analysis of the cis-acting translational elements within the 59 untranslated region of coxsackievirus B3: potential targets for antiviral action of antisense oligomers. Virology 228, 63-73.
28. Yang, D., Cheung, P., Sun, Y., Yuan, J., Zhang, H., Carthy, C. M., Anderson, D. R., Bohunek, L., Wilson, J. E. & McManus, B. M. (2003). A shine-dalgarno-like sequence mediates in vitro ribosomal internal entry and subsequent scanning for translation initiation of coxsackievirus B3 RNA. Virology 305, 31-43.
29. Zell, R., Ihle, Y., Seitz, S., Gündel, U., Wutzler, P. & Görlach, M. (2008). Poly(rC)-binding protein 2 interacts with the oligo(rC) tract of coxsackievirus B3. Biochem Biophys Res Commun 366, 917-921.