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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 20, 2011, Pages 6031-6035

Effect of lipophilicity modulation on inhibition of human rhinovirus capsid binders

(10) Morley, Andrew a Tomkinson, Nicholas a Cook, Andrew a MacDonald, Catherine a Weaver, Richard a King, Sarah a Jenkinson, Lesley a Unitt, John a McCrae, Christopher a Phillips, Tim a

a ASTRAZENECA (United Kingdom)

Author keywords

Human rhinovirus; Lipophilic ligand efficiency (LLE); Lipophilicity; VP1

Indexed keywords

ANTIVIRUS AGENT; CAPSID PROTEIN; PROTEIN VP1; PYRIDAZINE DERIVATIVE;

ANIMAL CELL; ARTICLE; DRUG STRUCTURE; HUMAN; HUMAN RHINOVIRUS; LIPOPHILICITY; NONHUMAN; RAT; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; VIRUS CAPSID; VIRUS INHIBITION;

ANIMALS; ANTIVIRAL AGENTS; CAPSID; CAPSID PROTEINS; HUMANS; MICROSOMES; PICORNAVIRIDAE INFECTIONS; PROTEIN BINDING; PYRIDAZINES; RATS; RATS, SPRAGUE-DAWLEY; RHINOVIRUS; STRUCTURE-ACTIVITY RELATIONSHIP;

HUMAN RHINOVIRUS SP.; MIRIDAE;

EID: 80052930014 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.08.083 Document Type: Article

Times cited : (4)

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