2-Ethoxybenzoxazole as a bioisosteric replacement of an ethyl benzoate group in a human rhinovirus (HRV) capsid binder

Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 8, 2005, Pages 2051-2055

  Brown, Renee N ^a   Cameron, Rachel ^a   Chalmers, David K ^a   Hamilton, Stephanie ^a   Luttick, Angela ^a   Krippner, Guy Y ^a   McConnell, Darryl B ^a   Nearn, Roland ^a   Stanislawski, Pauline C ^a   Tucker, Simon P ^a   Watson, Keith G ^a,b  

^a Biota Holdings Limited   (Australia)

^b WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Antiviral; Benzoxazole; Bioisostere; HRV; Rhinovirus

Indexed keywords

2 ALKOXYBENZOXAZOLE; 2 ALKYLTHIOBENZOXAZOLE; ANTIVIRUS AGENT; BENZALDEHYDE DERIVATIVE; BENZOIC ACID DERIVATIVE; BENZOTHIAZOLE DERIVATIVE; BENZOXAZOLE DERIVATIVE; BINDING PROTEIN; CAPSID PROTEIN; ESTER; ETHER DERIVATIVE; ETHYLBENZENE; OXIME DERIVATIVE; PIRODAVIR; PLECONARIL; PYRIDAZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; HUMAN RHINOVIRUS; NONHUMAN; SYNTHESIS; VIRUS ACTIVATION; VIRUS CAPSID; X RAY CRYSTALLOGRAPHY;

HUMAN RHINOVIRUS SP.; MIRIDAE; RHINOVIRUS;

EID: 20144389050     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.02.054     Document Type: Article

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