Assessment in vitro of radioprotective efficacy of curcumin and resveratrol

Radiation Measurements

Volumn 46, Issue 9, 2011, Pages 962-966

  Sebastià, Natividad ^a   Montoro, Alegria ^b   Montoro, Amparo ^a   Almonacid, Miguel ^b   Villaescusa, Juan Ignacio ^b   Cervera, José ^b   Such, Esperanza ^b   Silla, M Angeles ^b   Soriano, Jose Miguel ^a  

^a UNIVERSITY OF VALENCIA   (Spain)

^b HOSPITAL UNIVERSITARIO LA FE   (Spain)

Author keywords

Radiation; Curcumin; Lymphocytes; Radioprotector; Resveratrol

Indexed keywords

ANTI-INFLAMMATORIES; CELLULAR DAMAGE; CHROMOSOMAL ABERRATION; CURCUMA LONGA; CURCUMIN; DAMAGE PROTECTION; HUMAN BLOOD LYMPHOCYTES; IN-VITRO; LYMPHOCYTES; MAMMALIAN SYSTEMS; POLYPHENOLS; POSTIRRADIATION; PRE-TREATMENT; RADIATION-INDUCED; RADIATION-INDUCED DAMAGES; RADIOPROTECTIVE EFFICACY; RADIOPROTECTOR; RADIOPROTECTORS; RESVERATROL; TRANS-RESVERATROL;

CHROMOSOMES; FRUITS; IONIZING RADIATION; MAMMALS; PHENOLS;

DAMAGE DETECTION;

EID: 80052928842     PISSN: 13504487     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.radmeas.2011.05.009     Document Type: Conference Paper

References (33)

1. L. Almeida, M. Vaz-da-Silva, A. Falao, E. Soares, R. Costa, A.I. Loureiro, F. Fernandes-Lopes, J.F. Rocha, T. Nunes, L. Wright, and P. Soares-da-Silva Pharmacokinetic and safety profile of trans-resveratrol in a rising multiple-dose study in healthy volunteers Mol. Nutr. Food Res. 53 2009 7 15
2. B.B. Aggarwal, A. Kumar, and A.C. Bharti Anticancer potential of curcumin: preclinical and clinical studies Anticancer Res. 23 2003 363 398 (Pubitemid 36361976)
3. N. Aftab, and A. Vieira Antioxidant activities of curcumin and combinations of this curcuminoid with other phytochemicals Phytother. Res. 24 2010 500 502
4. R. Arora, D. Gupta, R. Chawla, R. Sagar, A. Sharma, R. Kumar, J. Prasad, S. Singh, N. Samanta, and R.K. Sharma Radioprotection by plant products: present status and future prospects Phytother. Res. 19 2005 1 22 (Pubitemid 40444988)
5. S. Baatout, H. Derradji, P. Jacquet, and M. Mergeay Increased radiation sensitivity of an eosinophilic cell line following treatment with epigallocatechin-gallate, resveratrol and curcuma Int. J. Mol. Med. 15 2008 337 352
6. M. Balasubramanyam, A.A. Koteswari, R. Sampath Kumar, S. Finny Monickaraj, J. Uma Maheswari, and V. Mohan Curcumin-induced inhibition of cellular reactive oxygen species generation: novel therapeutic implications J. Biosci. 28 2003 715 721 (Pubitemid 37522778)
7. M.S. Baliga, and S. Rao Radioprotective potential of mint: a brief review J. Cancer Res. Ther. 6 2010 255 262
8. V. Benkovic, N. Kopjar, A. Horvat Knezevic, D. Dikic, D. Lisicic, I. Basic, S. Ramic, T. Viculin, T. Knezevic, and N. Orsolic Evaluation of radioprotective effects of propolis and quercetin on human white blood cells in vitro Phytomedicine 15 2008 851 858
9. R.E. Carsten, A.M. Bachand, S.M. Bailey, and R.L. Ullricha Resveratrol reduces radiation-induced chromosome aberration frequencies in mouse bone marrow cells Radiat. Res. 169 2008 633 638 (Pubitemid 351793453)
10. K. Cavusoglu, and E. Yalcin Radioprotective effect of lycopene on chromosomal aberrations (CAs) induced by gamma radiation in human lymphocytes J. Environ. Biol. 30 2009 113 117
11. D. Citrin, A.P. Cotrim, F. Hyodo, B.J. Baum, M.C. Krishna, and J.B. Mitchell Radioprotectors and mitigators of radiation-induced normal tissue injury The Oncologist 15 2010 360 371
12. H. Ferry-Dumazet, O. Garnier, M. Mamani-Matsuda, J. Vercauteren, F. Belloc, C. Billiard, M. Dupouy, D. Thiolat, J.P. Kolb, G. Marit, J. Reiffers, and M.D. Mossalayi Resveratrol inhibits the growth and induces the apoptosis of both normal and leukemic hematopoietic cells Carcinogenesis 23 2002 1327 1333
13. C. Giovannini, C. Filesi, M. D'Archivio, B. Scazzocchio, C. Santangelo, and R. Masella Polyphenols and endogenous antioxidant defences: effects on glutathione and glutathione related enzymes Ann. Ist Super Sanita 42 2006 336 347 (Pubitemid 44899831)
14. A. Goel, and B.B. Aggarwal Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs Nutr. Cancer 62 2010 919 930
15. S.J. Hosseinimehr, H. Tavakoli, G. Pourheidari, A. Sobhani, and A. Shafiee Radioprotective effects of citrus extract against γ-irradiation in mouse bone marrow cells J. Radiat. Res. 44 2003 237 241 (Pubitemid 38738727)
16. IAEA Biological Dosimetry: Chromosomal Aberration Analysis for Dose Assessment Technical Reports Series 260 2001 International Atomic Energy Agency Vienna, Austria
17. M. Jang, L. Cai, G.O. Udeani, K.V. Slowing, C.F. Thomas, C.W.W. Beecher, H.H.S. Fong, N.R. Farnsworth, A.D. Kinghorn, R.G. Mehta, R.C. Moon, and J.M. Pezzuto Cancer chemopreventive activity of resveratrol, a natural product derived from grapes Science 275 1997 218 220 (Pubitemid 127696281)
18. T.K. Lee, R.M. Johnke, R.R. Allison, K.F. O'Brien Jr.; and L.J. Dobbs Radioprotective potential of gynseng Mutagenesis 20 2005 237 243
19. A.P.N. Majumdar, S. Banerjee, J. Nautiyal, B.B. Patel, V. Patel, J. Du, Y. Yu, D.K. Maurya, T.P. Devasagayam, and C.K. Nair Some novel approaches for radioprotection and the beneficial effect of natural products Indian J. Exp. Biol. 44 2006 93 114 (Pubitemid 43224071)
20. A. Montoro, M. Almonacid, J. Serrano, M. Saiz, J.F. Barquinero, L. Barrios, G. Verdu, J. Pérez, and J.I. Villaescusa Assessment by cytogenetic analysis of the radiprotection properties of propolis extract Radiat. Prot. Dosim. 115 2005 461 464 (Pubitemid 43103464)
21. Nadir Clinicaltrials.gov Available at http://clinicaltrials.gov/ct2/show/ NCT00486460?term=curcumin+phase+III&rank=2 2007
22. K. Polasa, N.A. Naidu, I. Ravindranath, and K. Krishanaswamy Inhibition of B(a)P induced strand breaks in presence of curcumin Mutat. Res. 557 2004 203 213 (Pubitemid 38071831)
23. N.R. Prasad, M. Srinivasan, K.V. Pugalendi, and V.P. Menon Protective effect of ferulic acid on γ-radiation-induced micronuclei, dicentric aberration and lipid peroxidation in human lymphocytes Mutat. Res. 603 2006 129 134 (Pubitemid 43224151)
24. Randal Clinical trials.gov Available at http://clinicaltrials.gov/ct2/ show/NCT00256334?term=resveratrol+phase+II&rank=4 2009
25. S. Shishodia, M.M. Chaturvedi, and B.B. Aggarwal Role of curcumin in cancer therapy Curr. Probl. Cancer 31 2007 243 305 (Pubitemid 47077491)
26. P. Signorelli, and T. Ghidoni Resveratrol as an anticancer nutrient: molecular basis, open questions and promises J. Nutr. Biochem. 16 2005 449 466 (Pubitemid 41039220)
27. K. Shimoi, S. Masuda, B. Shen, M. Furugori, and N. Kinae Radioprotective effects of antioxidative plant flavonoids in mice Mutat. Res. 350 1996 153 161 (Pubitemid 26072406)
28. M. Srinivasan, N.R. Prasad, and V.P. Menon Protective effect of curcumin on γ-radiation induced DNA damage and lipid peroxidation in cultured human lymphocytes Mutat. Res. 611 2006 96 103 (Pubitemid 44780183)
29. M. Srinivasan, N. Devipriya, K.B. Kalpana, and V.P. Menon Lycopene: an antioxidant and radioprotector against γ-radiation-induced cellular damages in cultured human lymphocytes Toxicology 262 2009 43 49
30. U. Stervbo, O. Vang, and C. Bonnesen A review of the content of the putative chemopreventive phytoalexin resveratrol in red wine Food Chem. 101 2007 449 457 (Pubitemid 44333178)
31. Vijayalaxmi, R.J. Reiter, and M.L. Meltz Melatonin protects human blood lymphocytes from radiation-induced chromosome damage Mutat. Res. 346 1995 23 31
32. J.F. Weiss, and M.R. Landauer Protection against ionizing radiation by antioxidant nutrients and phytochemicals Toxicology 189 2003 1 20 (Pubitemid 36725020)
33. G.C. Yen, P.D. Duh, and C.W. Lin Effects of resveratrol and 4-hexylresorcinol on hydrogen peroxide-induced oxidative DNA damage in human lymphocytes Free Rad. Res. 37 2003 509 514