-
1
-
-
1642523573
-
Inhibition of Cell Proliferation and Cell Cycle Progression by Specific Inhibition of Basal JNK Activity: Evidence that mitotic bcl-2 phosphorylation is JNK-independent
-
DOI 10.1074/jbc.M304935200
-
Du L, Lyle CS, Obey TB, Gaarde WA, Bennett BL, Chambers TC (2000) Inhibition of cell proliferation and cell cycle progression by specific inhibition of basal JNK activity: evidence that mitotic Bcl-2 phosphorylation is JNK-independent. J Biol Chem 279:11957-11966 (Pubitemid 38401701)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.12
, pp. 11957-11966
-
-
Du, L.1
Lyle, C.S.2
Obey, T.B.3
Gaarde, W.A.4
Muir, J.A.5
Bennett, B.L.6
Chambers, T.C.7
-
2
-
-
0345732500
-
2-terminal kinase (JNK) activation in multiple myeloma cell lines
-
DOI 10.1038/sj.onc.1206919
-
Hideshima T, Hayashi T, Chauhan D, Akiyama M, Richardson P, Anderson K (2003) Biologic sequelae of c-Jun NH2-terminal kinase (JNK) activation in multiple myeloma cell lines. Oncogene 22:8797-8801 (Pubitemid 38010503)
-
(2003)
Oncogene
, vol.22
, Issue.54
, pp. 8797-8801
-
-
Hideshima, T.1
Hayashi, T.2
Chauhan, D.3
Akiyama, M.4
Richardson, P.5
Anderson, K.6
-
3
-
-
3242810564
-
Jun N-terminal kinase promotes proliferation of immature erythroid cells and erythropoietin-dependent cell lines
-
DOI 10.1182/blood-2003-05-1754
-
Jacobs-Helber SM, Sawyer ST (2004) Jun N-terminal kinase promotes proliferation of immature erythroid cells and erythropoietin- dependent cell lines. Blood 104:696-703 (Pubitemid 38970562)
-
(2004)
Blood
, vol.104
, Issue.3
, pp. 696-703
-
-
Jacobs-Helber, S.M.1
Sawyer, S.T.2
-
4
-
-
0842329801
-
Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells
-
DOI 10.1038/sj.onc.1207147
-
Mingo-Sion AM, Marietta PM, Koller E, Wolf DM, Van Den Berg CL (2004) Inhibition of JNK reduces G2/M transit independent of p53, leading to endoreduplication, decreased proliferation, and apoptosis in breast cancer cells. Oncogene 23:596-604 (Pubitemid 38175015)
-
(2004)
Oncogene
, vol.23
, Issue.2
, pp. 596-604
-
-
Mingo-Sion, A.M.1
Marietta, P.M.2
Koller, E.3
Wolf, D.M.4
Van Den Berg, C.L.5
-
5
-
-
0842308312
-
All-trans retinoic acid potentiates Taxotere-induced cell death mediated by Jun N-terminal kinase in breast cancer cells
-
DOI 10.1038/sj.onc.1207040
-
Wang Q, Wieder R (2004) All-trans retinoic acid potentiates taxotere-induced cell death mediated by Jun-N-terminal kinase in breast cancer cells. Oncogene 23:426-433 (Pubitemid 38174997)
-
(2004)
Oncogene
, vol.23
, Issue.2
, pp. 426-433
-
-
Wang, Q.1
Wieder, R.2
-
6
-
-
23044453047
-
2/M cell cycle arrest
-
DOI 10.1158/0008-5472.CAN-04-2618
-
Kuntzen C, Sonuc N, De Toni EN, Opelz C, Mucha SR, Gerbes AL, Eichhorst ST (2005) Inhibition of c-Jun-N-terminal-kinase sensitizes tumor cells to CD95-induced apoptosis and induces G2/ M cell cycle arrest. Cancer Res 65:6780-6788 (Pubitemid 41060716)
-
(2005)
Cancer Research
, vol.65
, Issue.15
, pp. 6780-6788
-
-
Kuntzen, C.1
Sonuc, N.2
De Toni, E.N.3
Opelz, C.4
Mucha, S.R.5
Gerbes, A.L.6
Eichhorst, S.T.7
-
8
-
-
33845496093
-
P53 downstream target genes and tumor suppression: A classical view in evolution
-
DOI 10.1038/sj.cdd.4402058, PII 4402058
-
Rozan LM, El-Deiry WS (2007) p53 downstream target genes and tumor suppression: a classical view in evolution. Cell Death Differ 14:3-9 (Pubitemid 44911889)
-
(2007)
Cell Death and Differentiation
, vol.14
, Issue.1
, pp. 3-9
-
-
Rozan, L.M.1
El-Deiry, W.S.2
-
9
-
-
0028988585
-
1 cyclindependent kinases
-
Sherr CJ, Roberts JM (1995) Inhibitors of mammalian G1 cyclindependent kinases. Genes Dev 9:1149-1163
-
(1995)
Genes Dev
, vol.9
, pp. 1149-1163
-
-
Sherr, C.J.1
Roberts, J.M.2
-
10
-
-
0028352434
-
The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA
-
DOI 10.1038/369574a0
-
Waga S, Hannon GJ, Beach D, Stillman B (1994) The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA. Nature 369:574-578 (Pubitemid 24192528)
-
(1994)
Nature
, vol.369
, Issue.6481
, pp. 574-578
-
-
Waga, S.1
Hannon, G.J.2
Beach, D.3
Stillman, B.4
-
11
-
-
0028986639
-
Cip1 in muscle and other terminally differentiating cells
-
Parker SB, Eichele G, Zhang P, Rawls A, Sands AT, Bradley A, Olson EN, Harper JW, Elledge SJ (1995) p53-independent expression of p21Cip1 in muscle and other terminally differentiating cells. Science 267:1024-1027
-
(1995)
Science
, vol.267
, pp. 1024-1027
-
-
Parker, S.B.1
Eichele, G.2
Zhang, P.3
Rawls, A.4
Sands, A.T.5
Bradley, A.6
Olson, E.N.7
Harper, J.W.8
Elledge, S.J.9
-
12
-
-
0030997927
-
Redox-mediated regulation of p21(waf1/cip1) expression involves a post- transcriptional mechanism and activation of the mitogen-activated protein kinase pathway
-
Esposito F, Cuccovillo F, Vanoni M, Cimino F, Anderson CW, Appella E, Russo T (1997) Redox-mediated regulation of p21waf1/ cip1 expression involves a post-transcriptional mechanism and activation of the mitogen-activated protein kinase pathway. Eur J Biochem 245:730-737 (Pubitemid 27223907)
-
(1997)
European Journal of Biochemistry
, vol.245
, Issue.3
, pp. 730-737
-
-
Esposito, F.1
Cuccovillo, F.2
Vanoni, M.3
Cimino, F.4
Anderson, C.W.5
Appella, E.6
Russo, T.7
-
13
-
-
0033082834
-
WAF1 expression by an activator of protein kinase C is regulated mainly at the post-transcriptional level in cells lacking p53: Important role of RNA stabilization
-
Akashi M, Osawa Y, Koeffler HP, Hachiya M (1999) p21WAF1 expression by an activator of protein kinase C is regulated mainly at the post-transcriptional level in cells lacking p53: important role of RNA stabilization. Biochem J 337:607-616
-
(1999)
Biochem J
, vol.337
, pp. 607-616
-
-
Akashi, M.1
Osawa, Y.2
Koeffler, H.P.3
Hachiya, M.4
-
14
-
-
0033080402
-
(WAF1/CIP1) gene
-
Gartel AL, Tyner AL (1999) Transcriptional regulation of the p21(WAF1/CIP1) gene. Exp Cell Res 246:280-289
-
(1999)
Exp Cell Res
, vol.246
, pp. 280-289
-
-
Gartel, A.L.1
Tyner, A.L.2
-
15
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
DOI 10.1016/0092-8674(93)90500-P
-
el-Deiry WS, Tokino T, Velculescu VE, Levy DB, Parsons R, Trent JM, Lin D, Mercer WE, Kinzler KW, Vogelstein B (1993) WAF1, a potential mediator of p53 tumor suppression. Cell 75:817-825 (Pubitemid 23346378)
-
(1993)
Cell
, vol.75
, Issue.4
, pp. 817-825
-
-
El-Deiry, W.S.1
Tokino, T.2
Velculescu, V.E.3
Levy, D.B.4
Parsons, R.5
Trent, J.M.6
Lin, D.7
Mercer, W.E.8
Kinzler, K.W.9
Vogelstein, B.10
-
16
-
-
0034941567
-
Cip1 regulates PCNA binding and proliferation of endothelial cells
-
DOI 10.1128/MCB.21.16.5644-5657.2001
-
Rössig L, Jadidi AS, Urbich C, Badorff C, Zeiher AM, Dimmeler S (2001) Akt-dependent phosphorylation of p21Cip1 regulates PCNA binding and proliferation of endothelial cells. Mol Cell Biol 21:5644-5657 (Pubitemid 32702467)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.16
, pp. 5644-5657
-
-
Rossig, L.1
Jadidi, A.S.2
Urbich, C.3
Badorff, C.4
Zeiher, A.M.5
Dimmeler, S.6
-
17
-
-
0037192852
-
Cip/WAF1 and promotes cell survival
-
DOI 10.1074/jbc.M109062200
-
Li Y, Dowbenko D, Lasky LA (2002) AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival. J Biol Chem 277:11352-11361 (Pubitemid 34952901)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.13
, pp. 11352-11361
-
-
Li, Y.1
Dowbenko, D.2
Lasky, L.A.3
-
18
-
-
38049077461
-
Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter
-
Hwang-Verslues WW, Sladek FM (2008) Nuclear receptor hepatocyte nuclear factor 4alpha1 competes with oncoprotein c-Myc for control of the p21/WAF1 promoter. Mol Endocrinol 22:78-90
-
(2008)
Mol Endocrinol
, vol.22
, pp. 78-90
-
-
Hwang-Verslues, W.W.1
Sladek, F.M.2
-
19
-
-
0028829465
-
Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter
-
Datto MB, Yu Y, Wang XF (1995) Functional analysis of the transforming growth factor beta responsive elements in the WAF1/Cip1/p21 promoter. J Biol Chem 270:28623-28628
-
(1995)
J Biol Chem
, vol.270
, pp. 28623-28628
-
-
Datto, M.B.1
Yu, Y.2
Wang, X.F.3
-
20
-
-
0032541650
-
Increasing complexity of Ras signaling
-
Campbell SL, Khosravi-Far R, Rossman KL, Clark GJ, Der CJ (1998) Increasing complexity of Ras signaling. Oncogene 17:1395-1413 (Pubitemid 28458409)
-
(1998)
Oncogene
, vol.17
, Issue.11
, pp. 1395-1413
-
-
Campbell, S.L.1
Khosravi-Far, R.2
Rossman, K.L.3
Clark, G.J.4
Der, C.J.5
-
21
-
-
0024475228
-
Regulation of p34(cdc2) protein kinase during mitosis
-
DOI 10.1016/0092-8674(89)90850-7
-
Moreno S, Hayles J, Nurse P (1989) Regulation of p34cdc2 protein kinase during mitosis. Cell 58:361-372 (Pubitemid 19191417)
-
(1989)
Cell
, vol.58
, Issue.2
, pp. 361-372
-
-
Moreno, S.1
Hayles, J.2
Nurse, P.3
-
22
-
-
0034745353
-
CIP1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
-
DOI 10.1038/35060032
-
Zhou BP, Liao Y, Xia W, Spohn B, Lee MH, Hung MC (2001) Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells. Nat Cell Biol 3:245-252 (Pubitemid 32201319)
-
(2001)
Nature Cell Biology
, vol.3
, Issue.3
, pp. 245-252
-
-
Zhou, B.P.1
Liao, Y.2
Xia, W.3
Spohn, B.4
Lee, M.-H.5
Hung, M.-C.6
-
23
-
-
4344684649
-
PTEN function: How normal cells control it and tumour cells lose it
-
DOI 10.1042/BJ20040825
-
Leslie NR, Downes CP (2004) PTEN function: how normal cells control it and tumour cells lose it. Biochem J 382:1-11 (Pubitemid 39141560)
-
(2004)
Biochemical Journal
, vol.382
, Issue.1
, pp. 1-11
-
-
Leslie, N.R.1
Downes, C.P.2
-
25
-
-
0033104495
-
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
-
Asada M, Yamada T, Ichijo H, Delia D, Miyazono K, Fukumuro K, Mizutani S (1999) Apoptosis inhibitory activity of cytoplasmic p21Cip1/WAF1 in monocytic differentiation. EMBO J 18:1223-1234 (Pubitemid 29110307)
-
(1999)
EMBO Journal
, vol.18
, Issue.5
, pp. 1223-1234
-
-
Asada, M.1
Yamada, T.2
Ichijo, H.3
Delia, D.4
Miyazono, K.5
Fukumuro, K.6
Mizutani, S.7
-
26
-
-
0037304898
-
New roles for p21 and p27 cell-cycle inhibitors: A function for each cell compartment?
-
DOI 10.1016/S0962-8924(02)00043-0, PII S0962892402000430
-
Coqueret O (2003) New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends Cell Biol 13:65-70 (Pubitemid 36135887)
-
(2003)
Trends in Cell Biology
, vol.13
, Issue.2
, pp. 65-70
-
-
Coqueret, O.1
-
27
-
-
34247503812
-
Waf1/Cip1 as a novel mechanism of neuroprotection by glucocorticoids
-
DOI 10.1523/JNEUROSCI.5110-06.2007
-
Harms C, Albrecht K, Harms U, Seidel K, Hauck L, Baldinger T, Hübner D, Kronenberg G, An J, Ruscher K, Meisel A, Dirnagl U, von Harsdorf R, Endres M, Hörtnagl H (2007) Phosphatidylinositol 3-Akt-kinase-dependent phosphorylation of p21Waf1/Cip1 as a novel mechanism of neuroprotection by glucocorticoids. J Neurosci 27:4562-4571 (Pubitemid 46663587)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.17
, pp. 4562-4571
-
-
Harms, C.1
Albrecht, K.2
Harms, U.3
Seidel, K.4
Hauck, L.5
Baldinger, T.6
Hubner, D.7
Kronenberg, G.8
An, J.9
Ruscher, K.10
Meisel, A.11
Dirnagl, U.12
Von Harsdorf, R.13
Endres, M.14
Hortnagl, H.15
-
28
-
-
0034644522
-
Signal transduction by the JNK group of MAP kinases
-
Davis RJ (2000) Signal transduction by the JNK group of MAP kinases. Cell 103:239-252
-
(2000)
Cell
, vol.103
, pp. 239-252
-
-
Davis, R.J.1
-
29
-
-
0037230304
-
Activation of the JNK signaling pathway: Breaking the brake on apoptosis
-
DOI 10.1002/bies.10204
-
Lin A (2003) Activation of the JNK signaling pathway: breaking the brake on apoptosis. Bioessays 25:17-24 (Pubitemid 36093321)
-
(2003)
BioEssays
, vol.25
, Issue.1
, pp. 17-24
-
-
Lin, A.1
-
30
-
-
0027301324
-
Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation
-
Xiong Y, Zhang H, Beach D (1993) Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation. Genes Dev 7:1572-1583 (Pubitemid 23234350)
-
(1993)
Genes and Development
, vol.7
, Issue.8
, pp. 1572-1583
-
-
Xiong, Y.1
Zhang, H.2
Beach, D.3
-
31
-
-
4644333142
-
2-terminal kinase mediates survival of isolated human islets
-
DOI 10.1210/en.2004-0488
-
Aikin R, Maysinger D, Rosenberg L (2004) Cross-talk phosphatidylinositol 3-kinase/AKT and c-Jun NH2-terminal kinase mediates survival of isolated human islets. Endocrinology 145:4522-4531 (Pubitemid 39281444)
-
(2004)
Endocrinology
, vol.145
, Issue.10
, pp. 4522-4531
-
-
Aikin, R.1
Maysinger, D.2
Rosenberg, L.3
-
32
-
-
21244471120
-
Sustained Akt/PKB activation and transient attenuation of c-jun N-Terminal kinase in the inhibition of apoptosis by IGF-1 in vascular smooth muscle cells
-
DOI 10.1007/s10495-005-1882-3
-
Allen RT, Krueger KD, Dhume A, Agrawal DK (2005) Sustained Akt/PKB activation and transient attenuation of c-jun N-terminal kinase in the inhibition of apoptosis by IGF-1 in vascular smooth muscle cells. Apoptosis 10:525-535 (Pubitemid 40896659)
-
(2005)
Apoptosis
, vol.10
, Issue.3
, pp. 525-535
-
-
Allen, R.T.1
Krueger, K.D.2
Dhume, A.3
Agrawal, D.K.4
-
33
-
-
37549027687
-
Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation
-
Fornoni A, Pileggi A, Molano RD, Sanabria NY, Tejada T, Gonzalez-Quintana J, Ichii H, Inverardi L, Ricordi C, Pastori RL (2008) Inhibition of c-jun N terminal kinase (JNK) improves functional beta cell mass in human islets and leads to AKT and glycogen synthase kinase-3 (GSK-3) phosphorylation. Diabetologia 51:298-308
-
(2008)
Diabetologia
, vol.51
, pp. 298-308
-
-
Fornoni, A.1
Pileggi, A.2
Molano, R.D.3
Sanabria, N.Y.4
Tejada, T.5
Gonzalez-Quintana, J.6
Ichii, H.7
Inverardi, L.8
Ricordi, C.9
Pastori, R.L.10
-
34
-
-
42749096619
-
Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells
-
Moon DO, Kim MO, Choi YH, Kim ND, Chang JH, Kim GY (2008) Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells. Cancer Lett 264:316-325
-
(2008)
Cancer Lett
, vol.264
, pp. 316-325
-
-
Moon, D.O.1
Kim, M.O.2
Choi, Y.H.3
Kim, N.D.4
Chang, J.H.5
Kim, G.Y.6
-
35
-
-
0032910361
-
Mitochondrial regulation of cell death: Mitochondria are essential for procaspase 3-p21 complex formation to resist Fas-mediated cell death
-
Suzuki A, Tsutomi Y, Yamamoto N, Shibutani T, Akahane K (1999) Mitochondrial regulation of cell death: mitochondria are essential for procaspase 3-p21 complex formation to resist fasmediated cell death. Mol Cell Biol 19:3842-3847 (Pubitemid 29193843)
-
(1999)
Molecular and Cellular Biology
, vol.19
, Issue.5
, pp. 3842-3847
-
-
Suzuki, A.1
Tsutomi, Y.2
Yamamoto, N.3
Shibutani, T.4
Akahane, K.5
-
36
-
-
0034607117
-
P21(WAF1/CIP1) inhibits initiator caspase cleavage by TRAIL death receptor DR4
-
DOI 10.1006/bbrc.2000.2247
-
Xu SQ, El-Deiry WS (2000) p21WAF1/CIP1 inhibits initiator caspase cleavage by TRAIL death receptor DR4. Biochem Biophys Res Commun 269:179-190 (Pubitemid 30440274)
-
(2000)
Biochemical and Biophysical Research Communications
, vol.269
, Issue.1
, pp. 179-190
-
-
Xu, S.-Q.1
El-Deiry, W.S.2
-
37
-
-
0033104495
-
Apoptosis inhibitory activity of cytoplasmic p21(Cip1/WAF1) in monocytic differentiation
-
Asada M, Yamada T, Ichijo H, Delia D, Miyazono K, Fukumuro K, Mizutani S (1999) Apoptosis inhibitory activity of cytoplasmic p21 (Cip1/WAF1) in monocytic differentiation. EMBO J 18:1223-1234 (Pubitemid 29110307)
-
(1999)
EMBO Journal
, vol.18
, Issue.5
, pp. 1223-1234
-
-
Asada, M.1
Yamada, T.2
Ichijo, H.3
Delia, D.4
Miyazono, K.5
Fukumuro, K.6
Mizutani, S.7
-
38
-
-
2342618936
-
Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression
-
Liang J, Slingerland JM (2003) Multiple roles of the PI3K/PKB (Akt) pathway in cell cycle progression. Cell Cycle 2:339-345
-
(2003)
Cell Cycle
, vol.2
, pp. 339-345
-
-
Liang, J.1
Slingerland, J.M.2
-
39
-
-
43149102480
-
Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis
-
DOI 10.1242/jcs.009530
-
Maddika S, Ande SR, Wiechec E, Hansen LL, Wesselborg S, Los M (2008) Akt-mediated phosphorylation of CDK2 regulates its dual role in cell cycle progression and apoptosis. J Cell Sci 121:979-988 (Pubitemid 351639417)
-
(2008)
Journal of Cell Science
, vol.121
, Issue.7
, pp. 979-988
-
-
Maddika, S.1
Sande, S.R.2
Wiechec, E.3
Hansen, L.L.4
Wesselborg, S.5
Los, M.6
|