A low frequency variant within the GWAS locus of MTNR1B affects fasting glucose concentrations: Genetic risk is modulated by obesity

Nutrition, Metabolism and Cardiovascular Diseases

Volumn 22, Issue 11, 2012, Pages 944-951

  Been, L F ^a   Hatfield, J L ^a   Shankar, A ^a   Aston, C E ^a,b   Ralhan, S ^c   Wander, G S ^c   Mehra, N K ^d   Singh, J R ^e   Mulvihill, J J ^a   Sanghera, D K ^a  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF OKLAHOMA HEALTH SCIENCES CENTER   (United States)

^c Hero DMC Heart Institute   (India)

^d ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^e CENTRAL UNIVERSITY OF PUNJAB   (India)

Author keywords

Asian Indians; Fasting blood glucose; MTNR1B; SNP obesity interaction

Indexed keywords

MELATONIN 1 RECEPTOR; MTNR1B PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; ASIAN; BLOOD; BODY MASS; COHORT ANALYSIS; DIET RESTRICTION; DNA SEQUENCE; FEMALE; GENE FREQUENCY; GENE LOCUS; GENETIC ASSOCIATION; GENETICS; GENOTYPE; GLUCOSE BLOOD LEVEL; HUMAN; INDIA; INSULIN RESISTANCE; MALE; METABOLISM; MIDDLE AGED; NON INSULIN DEPENDENT DIABETES MELLITUS; OBESITY; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD GLUCOSE; BODY MASS INDEX; COHORT STUDIES; DIABETES MELLITUS, TYPE 2; FASTING; FEMALE; GENE FREQUENCY; GENETIC LOCI; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; INDIA; INSULIN RESISTANCE; MALE; MIDDLE AGED; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTOR, MELATONIN, MT1; RISK FACTORS; SEQUENCE ANALYSIS, DNA;

EID: 80052917184     PISSN: 09394753     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.numecd.2011.01.006     Document Type: Article

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