Negative regulation of dermal fibroblasts by enlarged adipocytes through release of free fatty acids

Journal of Investigative Dermatology

Volumn 131, Issue 10, 2011, Pages 2004-2009

  Ezure, Tomonobu ^a   Amano, Satoshi ^a  

^a SHISEIDO RESEARCH CENTER   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN TYPE 1; COLLAGENASE 3; ELASTIN; FATTY ACID; ICOSAPENTAENOIC ACID; PALMITIC ACID;

ADIPOCYTE; ADIPOSE TISSUE; ARTICLE; CELL CULTURE; CELL INTERACTION; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; OBESITY; PRIORITY JOURNAL; SKIN FIBROBLAST;

EID: 80052850714     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/jid.2011.145     Document Type: Article

References (22)

1. Decker T, Lohmann-Matthes ML (1988) A quick and simple method for the quantitation of lactate dehydrogenase release in measurements of cellular cytotoxicity and tumor necrosis factor (TNF) activity. J Immunol Methods 115:61-9
2. Ezure T, Amano S (2007) Adiponectin and leptin up-regulate extracellular matrix production by dermal fibroblasts. Biofactors 31:229-36 (Pubitemid 352789891)
3. Ezure T, Amano S (2009) Heat stimulation reduces early adipogenesis in 3T3-L1 preadipocytes. Endocrine 35:402-8
4. Ezure T, Amano S (2010a) Increased subcutaneous adipose tissue impairs dermal function in diet-induced obese mice. Exp Dermatol 19:878-82
5. Ezure T, Amano S (2010b) Influence of subcutaneous adipose tissue mass on dermal elasticity and sagging severity in lower cheek. Skin Res Technol 16:332-8
6. Ezure T, Hoshoi J, Amano S et al. (2009) Sagging of the cheek is related to skin elasticity, fat mass and mimetic muscle function. Skin Res Technol 15:299-305
7. Green H, Kehinde O (1975) An established preadipose cell line and its differentiation in culture. II. Factors affecting the adipose conversion. Cell 5:19-27
8. Klein J, Permana PA, Owecki M et al. (2007) What are subcutaneous adipocytes really good for? Exp Dermatol 16:45-70
9. Knudsen AM, Gallagher S (2003) Care of the obese patient with pressure ulcers. J Wound Ostomy Continence Nurs 30:111-8 (Pubitemid 36890714)
10. Kuang PP, Berk JL, Rishikof DC et al. (2002) NF-kappaB induced by IL-1beta inhibits elastin transcription and myofibroblast phenotype. Am J Physiol Cell Physiol 283:C58-65 (Pubitemid 34670548)
11. Lee JY, Plakidas A, Lee WH et al. (2003) Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids. J Lipid Res 44:479-86 (Pubitemid 37279695)
12. Lee JY, Sohn KH, Rhee SH et al. (2001) Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4. J Biol Chem 276:16683-9
13. Liu X, Miyazaki M, Flowers MT et al. (2010) Loss of stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate. Arterioscler Thromb Vasc Biol 30:31-8
14. Matsuzawa Y (2006) The metabolic syndrome and adipocytokines. FEBS Lett 580:2917-21 (Pubitemid 43729162)
15. Mengshol JA, Vincenti MP, Coon CI et al. (2000) Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. Arthritis Rheum 43:801-11
16. Ramirez-Zacarias JL, Castro-Munozledo F, Kuri-Harcuch W (1992) Quantita-tion of adipose conversion and triglycerides by staining intracytoplasmic lipids with Oil red O. Histochemistry 97:493-7
17. Rippe RA, Schrum LW, Stefanovic B et al. (1999) NF-kappaB inhibits expression of the alpha1(I) collagen gene. DNA Cell Biol 18:751-61 (Pubitemid 29504189)
18. Schaeffler A, Gross P, Buettner R et al. (2009) Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-kappaB pathway in adipocytes links nutritional signalling with innate immunity. Immunology 126: 233-45
19. Student AK, Hsu RY, Lane MD (1980) Induction of fatty acid synthetase synthesis in differentiating 3T3-L1 preadipocytes. J Biol Chem 255: 4745-50 (Pubitemid 10060752)
20. Suganami T, Nishida J, Ogawa Y (2005) A paracrine loop between adipocytes and macrophages aggravates inflammatory changes: role of free fatty acids and tumor necrosis factor alpha. Arterioscler Thromb Vasc Biol 25:2062-8 (Pubitemid 41416301)
21. Suganami T, Yuan X, Shimoda Y et al. (2009) Activating transcription factor 3 constitutes a negative feedback mechanism that attenuates saturated Fatty acid/toll-like receptor 4 signaling and macrophage activation in obese adipose tissue. Circ Res 105:25-32
22. Sugihara H, Toda S, Yonemitsu N et al. (2001) Effects of fat cells on keratinocytes and fibroblasts in a reconstructed rat skin model using collagen gel matrix culture. Br J Dermatol 144:244-53 (Pubitemid 32178801)