Comparative tissue distribution, biotransformation and associated biological effects by decabromodiphenyl ethane and decabrominated diphenyl ether in male rats after a 90-day oral exposure study

Environmental Science and Technology

Volumn 44, Issue 14, 2010, Pages 5655-5660

  Wang, Fuxin ^a,b   Wang, Jing ^c   Dai, Jiayin ^a   Hu, Guocheng ^a   Wang, Jianshe ^a   Luo, Xiaojun ^c   Mai, Bixian ^c  

^a INSTITUTE OF ZOOLOGY   (China)

^b GUANGZHOU INSTITUTE OF GEOCHEMISTRY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; BIODEGRADATION; BIOMOLECULES; ETHANE; ETHERS; MASS SPECTROMETRY; METABOLISM; METABOLITES; ORGANIC COMPOUNDS; PHOTODEGRADATION; VEGETABLE OILS;

BIOCHEMICAL PARAMETERS; BIOCONCENTRATION; BIOLOGICAL EFFECTS; BIOLOGICAL RESPONSE; CLINICAL CHEMISTRY; CORN OIL; DEBROMINATION; DECABROMINATED DIPHENYL ETHER; DECABROMODIPHENYL ETHANE; MALE RATS; MASS SPECTRA; METABOLIC PATHWAYS; MRNA EXPRESSION LEVEL; ORAL EXPOSURE; ORDERS OF MAGNITUDE; POTENTIAL RISKS; RELATIVE RETENTION TIME; THYROID HORMONES; TISSUE DISTRIBUTIONS; TOXIC EFFECT;

RATS;

ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILE ACID; CHOLESTEROL; CORN OIL; CREATININE; DECABROMINATED DIPHENYL ETHER; DECABROMODIPHENYL ETHANE; ENZYME; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIOTHYRONINE; MESSENGER RNA; ORGANOBROMINE DERIVATIVE; THYROID HORMONE; THYROXINE; UNCLASSIFIED DRUG; BROMOBENZENE; DECABROMOBIPHENYL ETHER; DIPHENYL ETHER DERIVATIVE; POLLUTANT;

BIOAVAILABILITY; BIOCHEMISTRY; BIOTRANSFORMATION; DATABASE; ETHANE; ETHER; GAS CHROMATOGRAPHY; HORMONE; MALE; MASS SPECTROMETRY; METABOLITE; ORGANIC POLLUTANT; PHOTODEGRADATION; RODENT; TOXICITY; VEGETABLE OIL;

ADIPOSE TISSUE; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILE ACID BLOOD LEVEL; BIOTRANSFORMATION; CHOLESTEROL BLOOD LEVEL; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DEBROMINATION; DRUG EXPOSURE; ENVIRONMENTAL EXPOSURE; ENZYME BLOOD LEVEL; EXPERIMENTAL MODEL; EXPERIMENTAL RAT; GAS CHROMATOGRAPHY; KIDNEY; LIOTHYRONINE BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; LIVER; LIVER TOXICITY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PHOTODEGRADATION; RADIOIMMUNOASSAY; RAT; RISK FACTOR; THYROID HORMONE BLOOD LEVEL; THYROXINE BLOOD LEVEL; TISSUE DISTRIBUTION; ANIMAL; CHEMISTRY; METABOLISM; ORAL DRUG ADMINISTRATION; POLLUTANT;

ADMINISTRATION, ORAL; ANIMALS; BIOTRANSFORMATION; BROMOBENZENES; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL POLLUTANTS; HALOGENATED DIPHENYL ETHERS; MALE; RATS; TISSUE DISTRIBUTION;

EID: 77954577255     PISSN: 0013936X     EISSN: 15205851     Source Type: Journal    
DOI: 10.1021/es101158e     Document Type: Article

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