메뉴 건너뛰기




Volumn 14, Issue 5, 2010, Pages

Tranexamic acid in cardiac surgery: Is there a cause for concern?

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; AMINOCAPROIC ACID; APROTININ; TRANEXAMIC ACID;

EID: 80052782513     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc9227     Document Type: Note
Times cited : (9)

References (13)
  • 1
    • 77955117750 scopus 로고    scopus 로고
    • Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis
    • 10.1186/cc9216, 20682059
    • Sander M, Spies CD, Martiny V, Rosenthal C, Wernecke KD, von Heymann C. Mortality associated with administration of high-dose tranexamic acid and aprotinin in primary open-heart procedures: a retrospective analysis. Crit Care 2010, 14:R148. 10.1186/cc9216, 20682059.
    • (2010) Crit Care , vol.14
    • Sander, M.1    Spies, C.D.2    Martiny, V.3    Rosenthal, C.4    Wernecke, K.D.5    von Heymann, C.6
  • 2
    • 80052778825 scopus 로고    scopus 로고
    • EMA
    • EMA. , http://www.ema.europa.eu/pdfs/human/press/pr/10757010en.pdf
  • 3
    • 0028797713 scopus 로고
    • The dose-response relationship of tranexamic acid
    • 10.1097/00000542-199502000-00009, 7856897
    • Horrow JC, Van Riper DF, Strong MD, Grunewald KE, Parmet JL. The dose-response relationship of tranexamic acid. Anesthesiology 1995, 82:383-392. 10.1097/00000542-199502000-00009, 7856897.
    • (1995) Anesthesiology , vol.82 , pp. 383-392
    • Horrow, J.C.1    Van Riper, D.F.2    Strong, M.D.3    Grunewald, K.E.4    Parmet, J.L.5
  • 4
    • 58649087589 scopus 로고    scopus 로고
    • Antifibrinolytics in cardiac surgical patients receiving aspirin: a systematic review and meta-analysis
    • 10.1093/bja/aen377, 19151047
    • McIlroy DR, Myles PS, Phillips LE, Smith JA. Antifibrinolytics in cardiac surgical patients receiving aspirin: a systematic review and meta-analysis. Br J Anaesth 2009, 102:168-178. 10.1093/bja/aen377, 19151047.
    • (2009) Br J Anaesth , vol.102 , pp. 168-178
    • McIlroy, D.R.1    Myles, P.S.2    Phillips, L.E.3    Smith, J.A.4
  • 5
    • 58849137661 scopus 로고    scopus 로고
    • The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis
    • 2621296, 19050037
    • Henry D, Carless P, Fergusson D, Laupacis A. The safety of aprotinin and lysine-derived antifibrinolytic drugs in cardiac surgery: a meta-analysis. CMAJ 2009, 180:183-193. 2621296, 19050037.
    • (2009) CMAJ , vol.180 , pp. 183-193
    • Henry, D.1    Carless, P.2    Fergusson, D.3    Laupacis, A.4
  • 6
    • 74049141396 scopus 로고    scopus 로고
    • The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery
    • 10.1213/ANE.0b013e3181c0ea6d, 19910626
    • Karkouti K, Wijeysundera DN, Yau TM, McCluskey SA, Tait G, Beattie WS. The risk-benefit profile of aprotinin versus tranexamic acid in cardiac surgery. Anesth Analg 2009, 110:21-29. 10.1213/ANE.0b013e3181c0ea6d, 19910626.
    • (2009) Anesth Analg , vol.110 , pp. 21-29
    • Karkouti, K.1    Wijeysundera, D.N.2    Yau, T.M.3    McCluskey, S.A.4    Tait, G.5    Beattie, W.S.6
  • 7
    • 0019500844 scopus 로고
    • Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial
    • 10.1227/00006123-198102000-00004, 7010203
    • Fodstad H, Forssell A, Liliequist B, Schannong M. Antifibrinolysis with tranexamic acid in aneurysmal subarachnoid hemorrhage: a consecutive controlled clinical trial. Neurosurgery 1981, 8:158-165. 10.1227/00006123-198102000-00004, 7010203.
    • (1981) Neurosurgery , vol.8 , pp. 158-165
    • Fodstad, H.1    Forssell, A.2    Liliequist, B.3    Schannong, M.4
  • 8
    • 0016606365 scopus 로고
    • Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses
    • 1330803, 1079871
    • Barker JL, Nicoll RA, Padjen A. Studies on convulsants in the isolated frog spinal cord. I. Antagonism of amino acid responses. J Physiol Lond 1975, 245:521-536. 1330803, 1079871.
    • (1975) J Physiol Lond , vol.245 , pp. 521-536
    • Barker, J.L.1    Nicoll, R.A.2    Padjen, A.3
  • 9
    • 0036196828 scopus 로고    scopus 로고
    • Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect
    • 10.1124/jpet.301.1.168, 11907171
    • Furtmüller R, Schlag MG, Berger M, Hopf R, Huck S, Sieghart W, Redl H. Tranexamic acid, a widely used antifibrinolytic agent, causes convulsions by a gamma-aminobutyric acid(A) receptor antagonistic effect. J Pharmacol Exp Ther 2002, 301:168-173. 10.1124/jpet.301.1.168, 11907171.
    • (2002) J Pharmacol Exp Ther , vol.301 , pp. 168-173
    • Furtmüller, R.1    Schlag, M.G.2    Berger, M.3    Hopf, R.4    Huck, S.5    Sieghart, W.6    Redl, H.7
  • 10
    • 0018276205 scopus 로고
    • Seizure after infusion of aminocaproic acid
    • 10.1001/jama.240.22.2468, 101682
    • Feffer SE, Parray HR, Westring DW. Seizure after infusion of aminocaproic acid. JAMA 1978, 240:2468. 10.1001/jama.240.22.2468, 101682.
    • (1978) JAMA , vol.240 , pp. 2468
    • Feffer, S.E.1    Parray, H.R.2    Westring, D.W.3
  • 11
    • 58149293358 scopus 로고    scopus 로고
    • The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients
    • 10.1213/ane.0b013e318184bc20, 19020118
    • Martin K, Wiesner G, Breuer T, Lange R, Tassani P. The risks of aprotinin and tranexamic acid in cardiac surgery: a one-year follow-up of 1188 consecutive patients. Anesth Analg 2008, 107:1783-1790. 10.1213/ane.0b013e318184bc20, 19020118.
    • (2008) Anesth Analg , vol.107 , pp. 1783-1790
    • Martin, K.1    Wiesner, G.2    Breuer, T.3    Lange, R.4    Tassani, P.5
  • 12
    • 76249100902 scopus 로고    scopus 로고
    • High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients
    • 10.1213/ANE.0b013e3181c92b23, 19996135
    • Murkin JM, Falter F, Granton J, Young B, Burt C, Chu M. High-dose tranexamic Acid is associated with nonischemic clinical seizures in cardiac surgical patients. Anesth Analg 2010, 110:350-353. 10.1213/ANE.0b013e3181c92b23, 19996135.
    • (2010) Anesth Analg , vol.110 , pp. 350-353
    • Murkin, J.M.1    Falter, F.2    Granton, J.3    Young, B.4    Burt, C.5    Chu, M.6
  • 13
    • 0023204701 scopus 로고
    • Effect of aprotinin on need for blood transfusion after repeat open-heart surgery
    • 10.1016/S0140-6736(87)91190-1, 2446091
    • Royston D, Bidstrup BP, Taylor KM, Sapsford RN. Effect of aprotinin on need for blood transfusion after repeat open-heart surgery. Lancet 1987, 2:1289-1291. 10.1016/S0140-6736(87)91190-1, 2446091.
    • (1987) Lancet , vol.2 , pp. 1289-1291
    • Royston, D.1    Bidstrup, B.P.2    Taylor, K.M.3    Sapsford, R.N.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.