-
1
-
-
0035100888
-
Biomarkers and surrogate endpoints: Preferred definitions and conceptual framework
-
Biomarkers and surrogate endpoints: preferred definitions and conceptual framework. Clin Pharmacol Ther 2001; 69:89-95.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 89-95
-
-
-
3
-
-
33845974419
-
Biomarkers and surrogate end points for fit-for-purpose development and regulatory evaluation of new drugs
-
DOI 10.1038/sj.clpt.6100017, PII 6100017
-
Wagner JA, Williams SA, Webster CJ. Biomarkers and surrogate end points for fit-for purpose development and regulatory evaluation of new drugs. Clin Pharmacol Ther 2007; 81:104-107. (Pubitemid 46050874)
-
(2007)
Clinical Pharmacology and Therapeutics
, vol.81
, Issue.1
, pp. 104-107
-
-
Wagner, J.A.1
Williams, S.A.2
Webster, C.J.3
-
4
-
-
33744527833
-
Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock
-
DOI 10.1097/01.CCM.0000217961.75225.E9, PII 0000324620060600000001
-
Kumar A, Roberts D, Wood KE, et al. Duration of hypotension before initiation of effective antimicrobial therapy is the critical determinant of survival in human septic shock. Crit Care Med 2006; 34:1589-1596. (Pubitemid 43810035)
-
(2006)
Critical Care Medicine
, vol.34
, Issue.6
, pp. 1589-1596
-
-
Kumar, A.1
Roberts, D.2
Wood, K.E.3
Light, B.4
Parrillo, J.E.5
Sharma, S.6
Suppes, R.7
Feinstein, D.8
Zanotti, S.9
Taiberg, L.10
Gurka, D.11
Kumar, A.12
Cheang, M.13
-
5
-
-
26444545385
-
Early changes in organ function predict eventual survival in severe sepsis
-
Levy MM, Macias WL, Vincent JL, et al. Early changes in organ function predict eventual survival in severe sepsis. Crit Care Med 2005; 33:2194-2201.
-
(2005)
Crit Care Med
, vol.33
, pp. 2194-2201
-
-
Levy, M.M.1
MacIas, W.L.2
Vincent, J.L.3
-
6
-
-
0035829842
-
Early goal-directed therapy in the treatment of severe sepsis and septic shock
-
Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-1377.
-
(2001)
N Engl J Med
, vol.345
, pp. 1368-1377
-
-
Rivers, E.1
Nguyen, B.2
Havstad, S.3
-
7
-
-
65949116168
-
The pathogenetic and prognostic value of biologic markers in acute lung injury
-
Levitt JE, Gould MK, Ware LB, Matthay MA. The pathogenetic and prognostic value of biologic markers in acute lung injury. J Intensive Care Med 2009; 24:151-167.
-
(2009)
J Intensive Care Med
, vol.24
, pp. 151-167
-
-
Levitt, J.E.1
Gould, M.K.2
Ware, L.B.3
Matthay, M.A.4
-
8
-
-
76749100153
-
Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury
-
Ware LB, Koyama T, Billheimer DD, et al. Prognostic and pathogenetic value of combining clinical and biochemical indices in patients with acute lung injury. Chest 2010; 137:288-296.
-
(2010)
Chest
, vol.137
, pp. 288-296
-
-
Ware, L.B.1
Koyama, T.2
Billheimer, D.D.3
-
9
-
-
79551536820
-
Genetic variation in the FAS gene and associations with acute lung injury
-
Glavan BJ, Holden TD, Goss CH, et al. Genetic variation in the FAS gene and associations with acute lung injury. Am J Respir Crit Care Med 2011; 183:356-363.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 356-363
-
-
Glavan, B.J.1
Holden, T.D.2
Goss, C.H.3
-
10
-
-
34548383501
-
Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspase-independent pathway
-
DOI 10.1189/jlb.1006652
-
Altemeier WA, Zhu X, Berrington WR, et al. Fas (CD95) induces macrophage proinflammatory chemokine production via a MyD88-dependent, caspaseindependent pathway. J Leukoc Biol 2007; 82:721-728. (Pubitemid 47367164)
-
(2007)
Journal of Leukocyte Biology
, vol.82
, Issue.3
, pp. 721-728
-
-
Altemeier, W.A.1
Zhu, X.2
Berrington, W.R.3
Harlan, J.M.4
Liles, W.C.5
-
11
-
-
24744470277
-
Fas-mediated acute lung injury requires Fas expression on nonmyeloid cells of the lung
-
Matute-Bello G, Lee JS, Liles WC, et al. Fas-mediated acute lung injury requires fas expression on nonmyeloid cells of the lung. J Immunol 2005; 175:4069-4075. (Pubitemid 41292070)
-
(2005)
Journal of Immunology
, vol.175
, Issue.6
, pp. 4069-4075
-
-
Matute-Bello, G.1
Lee, J.S.2
Liles, W.C.3
Frevert, C.W.4
Mongovin, S.5
Wong, V.6
Ballman, K.7
Sutlief, S.8
Martin, T.R.9
-
12
-
-
78650668101
-
Metabolic consequences of sepsis-induced acute lung injury revealed by plasma (1)H-nuclear magnetic resonance quantitative metabolomics and computational analysis
-
Stringer KA, Serkova NJ, Karnovsky A, et al. Metabolic consequences of sepsis-induced acute lung injury revealed by plasma (1)H-nuclear magnetic resonance quantitative metabolomics and computational analysis. Am J Physiol Lung Cell Mol Physiol 2011; 300:L4-L11.
-
(2011)
Am J Physiol Lung Cell Mol Physiol
, Issue.300
-
-
Stringer, K.A.1
Serkova, N.J.2
Karnovsky, A.3
-
13
-
-
77953523394
-
Of mice and men: Comparative proteomics of bronchoalveolar fluid
-
Gharib SA, Nguyen E, Altemeier WA, et al. Of mice and men: comparative proteomics of bronchoalveolar fluid. Eur Respir J 2010; 35:1388-1395.
-
(2010)
Eur Respir J
, vol.35
, pp. 1388-1395
-
-
Gharib, S.A.1
Nguyen, E.2
Altemeier, W.A.3
-
14
-
-
70349392958
-
Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung
-
Lee JW, Fang X, Gupta N, et al. Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung. Proc Natl Acad Sci U S A 2009; 106:16357-16362.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16357-16362
-
-
Lee, J.W.1
Fang, X.2
Gupta, N.3
-
15
-
-
79952275726
-
Biomarkers of lung injury after one-lung ventilation for lung resection
-
Bastin AJ, Sato H, Davidson SJ, et al. Biomarkers of lung injury after one-lung ventilation for lung resection. Respirology 2011; 16:138-145.
-
(2011)
Respirology
, vol.16
, pp. 138-145
-
-
Bastin, A.J.1
Sato, H.2
Davidson, S.J.3
-
17
-
-
70449637194
-
Accuracy of neutrophil gelatinaseassociated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: A systematic review and meta-analysis
-
Haase M, Bellomo R, Devarajan P, et al. Accuracy of neutrophil gelatinaseassociated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis. Am J Kidney Dis 2009; 54:1012-1024.
-
(2009)
Am J Kidney Dis
, vol.54
, pp. 1012-1024
-
-
Haase, M.1
Bellomo, R.2
Devarajan, P.3
-
18
-
-
77951208845
-
Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population
-
Cruz DN, de Cal M, Garzotto F, et al. Plasma neutrophil gelatinase-associated lipocalin is an early biomarker for acute kidney injury in an adult ICU population. Intensive Care Med 2010; 36:444-451.
-
(2010)
Intensive Care Med
, vol.36
, pp. 444-451
-
-
Cruz, D.N.1
De Cal, M.2
Garzotto, F.3
-
19
-
-
77951208316
-
Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus nonseptic acute kidney injury in critical illness
-
Bagshaw SM, Bennett M, Haase M, et al. Plasma and urine neutrophil gelatinase-associated lipocalin in septic versus nonseptic acute kidney injury in critical illness. Intensive Care Med 2010; 36:452-461.
-
(2010)
Intensive Care Med
, vol.36
, pp. 452-461
-
-
Bagshaw, S.M.1
Bennett, M.2
Haase, M.3
-
20
-
-
77956171921
-
Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury
-
Martensson J, Bell M, Oldner A, et al. Neutrophil gelatinase-associated lipocalin in adult septic patients with and without acute kidney injury. Intensive Care Med 2010; 36:1333-1340.
-
(2010)
Intensive Care Med
, vol.36
, pp. 1333-1340
-
-
Martensson, J.1
Bell, M.2
Oldner, A.3
-
21
-
-
77951207233
-
Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: Relation to acute kidney injury, multiple organ dysfunction syndrome and outcome
-
Kumpers P, Hafer C, David S, et al. Angiopoietin-2 in patients requiring renal replacement therapy in the ICU: relation to acute kidney injury, multiple organ dysfunction syndrome and outcome. Intensive Care Med 2010; 36:462-470.
-
(2010)
Intensive Care Med
, vol.36
, pp. 462-470
-
-
Kumpers, P.1
Hafer, C.2
David, S.3
-
22
-
-
77955915903
-
Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial)
-
Endre ZH, Walker RJ, Pickering JW, et al. Early intervention with erythropoietin does not affect the outcome of acute kidney injury (the EARLYARF trial). Kidney Int 2010; 77:1020-1030.
-
(2010)
Kidney Int
, vol.77
, pp. 1020-1030
-
-
Zh, E.1
Walker, R.J.2
Pickering, J.W.3
-
23
-
-
79955624311
-
Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function
-
Endre ZH, Pickering JW, Walker RJ, et al. Improved performance of urinary biomarkers of acute kidney injury in the critically ill by stratification for injury duration and baseline renal function. Kidney Int 2011; 79:1119-1130.
-
(2011)
Kidney Int
, vol.79
, pp. 1119-1130
-
-
Zh, E.1
Pickering, J.W.2
Walker, R.J.3
-
24
-
-
79951984011
-
Evaluation of kidney oxygen bioavailability in acute renal failure by blood oxygen level dependent magnetic resonance imaging
-
Xiao WB, Wang QD, Xu JJ, et al. Evaluation of kidney oxygen bioavailability in acute renal failure by blood oxygen level dependent magnetic resonance imaging. Zhejiang Da Xue Xue Bao Yi Xue Ban 2010; 39:157-162.
-
(2010)
Zhejiang da Xue Xue Bao Yi Xue Ban
, vol.39
, pp. 157-162
-
-
Xiao, W.B.1
Wang, Q.D.2
Xu, J.J.3
-
25
-
-
77954585211
-
Multiphoton imaging techniques in acute kidney injury
-
Molitoris BA, Sandoval RM. Multiphoton imaging techniques in acute kidney injury. Contrib Nephrol 2010; 165:46-53.
-
(2010)
Contrib Nephrol
, vol.165
, pp. 46-53
-
-
Molitoris, B.A.1
Sandoval, R.M.2
-
26
-
-
78751653578
-
Diagnostic accuracy of Doppler renal resistive index for reversibility of acute kidney injury in critically ill patients
-
Darmon M, Schortgen F, Vargas F, et al. Diagnostic accuracy of Doppler renal resistive index for reversibility of acute kidney injury in critically ill patients. Intensive Care Med 2011; 37:68-76.
-
(2011)
Intensive Care Med
, vol.37
, pp. 68-76
-
-
Darmon, M.1
Schortgen, F.2
Vargas, F.3
-
28
-
-
33847056146
-
Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis
-
DOI 10.1016/S1473-3099(07)70052-X, PII S147330990770052X
-
Tang BM, Eslick GD, Craig JC, McLean AS. Accuracy of procalcitonin for sepsis diagnosis in critically ill patients: systematic review and meta-analysis. Lancet Infect Dis 2007; 7:210-217. (Pubitemid 46274517)
-
(2007)
Lancet Infectious Diseases
, vol.7
, Issue.3
, pp. 210-217
-
-
Tang, B.M.1
Eslick, G.D.2
Craig, J.C.3
McLean, A.S.4
-
29
-
-
33745622134
-
Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: A systematic review and meta-analysis
-
DOI 10.1097/01.CCM.0000226413.54364.36, PII 0000324620060700000020
-
Uzzan B, Cohen R, Nicolas P, et al. Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis. Crit Care Med 2006; 34:1996-2003. (Pubitemid 43982479)
-
(2006)
Critical Care Medicine
, vol.34
, Issue.7
, pp. 1996-2003
-
-
Uzzan, B.1
Cohen, R.2
Nicolas, P.3
Cucherat, M.4
Perret, G.-Y.5
-
30
-
-
78149425934
-
Predictive value of procalcitonin decrease in patients with severe sepsis: A prospective observational study
-
Karlsson S, Heikkinen M, Pettila V, et al. Predictive value of procalcitonin decrease in patients with severe sepsis: a prospective observational study. Crit Care 2010; 14:R205.
-
(2010)
Crit Care
, vol.14
-
-
Karlsson, S.1
Heikkinen, M.2
Pettila, V.3
-
31
-
-
2442544541
-
Diagnostic and prognostic value of procalcitonin in patients with septic shock
-
DOI 10.1097/01.CCM.0000126263.00551.06
-
Clec'h C, Ferriere F, Karoubi P, et al. Diagnostic and prognostic value of procalcitonin in patients with septic shock. Crit Care Med 2004; 32:1166-1169. (Pubitemid 38620986)
-
(2004)
Critical Care Medicine
, vol.32
, Issue.5
, pp. 1166-1169
-
-
Clec'h, C.1
Ferriere, F.2
Karoubi, P.3
Fosse, J.P.4
Cupa, M.5
Hoang, P.6
Cohen, Y.7
-
32
-
-
75949113583
-
Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): A multicentre randomised controlled trial
-
Bouadma L, Luyt CE, Tubach F, et al. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial. Lancet 2010; 375:463-474.
-
(2010)
Lancet
, vol.375
, pp. 463-474
-
-
Bouadma, L.1
Luyt, C.E.2
Tubach, F.3
-
33
-
-
79959743458
-
2nd. Plasma biomarkers of oxidant stress and development of organ failure in severe sepsis
-
Ware LB, Fessel JP, May AK, Roberts LJ, 2nd. Plasma biomarkers of oxidant stress and development of organ failure in severe sepsis. Shock 2011; 36:12-17.
-
(2011)
Shock
, vol.36
, pp. 12-17
-
-
Ware, L.B.1
Fessel, J.P.2
May, A.K.3
Roberts, L.J.4
-
34
-
-
77951239929
-
Increased plasma thioredoxin levels in patients with sepsis: Positive association with macrophage migration inhibitory factor
-
Leaver SK, MacCallum NS, Pingle V, et al. Increased plasma thioredoxin levels in patients with sepsis: positive association with macrophage migration inhibitory factor. Intensive Care Med 2010; 36:336-341.
-
(2010)
Intensive Care Med
, vol.36
, pp. 336-341
-
-
Leaver, S.K.1
MacCallum, N.S.2
Pingle, V.3
-
35
-
-
77950865172
-
Plasma proteome to look for diagnostic biomarkers of early bacterial sepsis after liver transplantation: A preliminary study
-
Paugam-Burtz C, Albuquerque M, Baron G, et al. Plasma proteome to look for diagnostic biomarkers of early bacterial sepsis after liver transplantation: a preliminary study. Anesthesiology 2010; 112:926-935.
-
(2010)
Anesthesiology
, vol.112
, pp. 926-935
-
-
Paugam-Burtz, C.1
Albuquerque, M.2
Baron, G.3
-
36
-
-
74949089131
-
Beta2-Adrenergic receptor gene polymorphism is associated with mortality in septic shock
-
Nakada TA, Russell JA, Boyd JH, et al. beta2-Adrenergic receptor gene polymorphism is associated with mortality in septic shock. Am J Respir Crit Care Med 2010; 181:143-149.
-
(2010)
Am J Respir Crit Care Med
, vol.181
, pp. 143-149
-
-
Nakada, T.A.1
Russell, J.A.2
Boyd, J.H.3
-
37
-
-
79958829910
-
Therapeutics: New drugs hit the target
-
10.1038/474S5a
-
Schlutter J. Therapeutics: new drugs hit the target. Nature [10.1038/474S5a] 2011; 474:S5-S7.
-
(2011)
Nature
, vol.474
-
-
Schlutter, J.1
-
38
-
-
79953765304
-
Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036
-
Chan WW, Wise SC, Kaufman MD, et al. Conformational control inhibition of the BCR-ABL1 tyrosine kinase, including the gatekeeper T315I mutant, by the switch-control inhibitor DCC-2036. Cancer Cell 2011; 19:556-568.
-
(2011)
Cancer Cell
, vol.19
, pp. 556-568
-
-
Chan, W.W.1
Wise, S.C.2
Kaufman, M.D.3
-
40
-
-
14944362300
-
A role for hydroxy-methylglutaryl coenzyme A reductase in pulmonary inflammation and host defense
-
DOI 10.1164/rccm.200406-729OC
-
Fessler MB, Young SK, Jeyaseelan S, et al. A role for hydroxy-methylglutaryl coenzyme A reductase in pulmonary inflammation and host defense. Am J Respir Crit Care Med 2005; 171:606-615; Epub 2004 Dec 10. (Pubitemid 40365416)
-
(2005)
American Journal of Respiratory and Critical Care Medicine
, vol.171
, Issue.6
, pp. 606-615
-
-
Fessler, M.B.1
Young, S.K.2
Jeyaseelan, S.3
Lieber, J.G.4
Arndt, P.G.5
Nick, J.A.6
Worthen, G.S.7
-
41
-
-
2342640996
-
Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin
-
DOI 10.1165/rcmb.2003-0267OC
-
Jacobson JR, Dudek SM, Birukov KG, et al. Cytoskeletal activation and altered gene expression in endothelial barrier regulation by simvastatin. Am J Respir Cell Mol Biol 2004; 30:662-670. (Pubitemid 38591217)
-
(2004)
American Journal of Respiratory Cell and Molecular Biology
, vol.30
, Issue.5
, pp. 662-670
-
-
Jacobson, J.R.1
Dudek, S.M.2
Birukov, K.G.3
Ye, S.Q.4
Grigoryev, D.N.5
Girgis, R.E.6
Garcia, J.G.N.7
-
42
-
-
0036633659
-
A 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall
-
DOI 10.1067/mva.2002.123680
-
Nagashima H, Aoka Y, Sakomura Y, et al. A 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, cerivastatin, suppresses production of matrix metalloproteinase-9 in human abdominal aortic aneurysm wall. J Vasc Surg 2002; 36:158-163. (Pubitemid 41122905)
-
(2002)
Journal of Vascular Surgery
, vol.36
, Issue.1
, pp. 158-163
-
-
Nagashima, H.1
Aoka, Y.2
Sakomura, Y.3
Sakuta, A.4
Aomi, S.5
Ishizuka, N.6
Hagiwara, N.7
Kawana, M.8
Kasanuki, H.9
-
43
-
-
65449179667
-
Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers
-
Shyamsundar M, McKeown ST, O'Kane CM, et al. Simvastatin decreases lipopolysaccharide-induced pulmonary inflammation in healthy volunteers. Am J Respir Crit Care Med 2009; 179:1107-1114.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 1107-1114
-
-
Shyamsundar, M.1
McKeown, S.T.2
O'kane, C.M.3
-
44
-
-
79952240186
-
A randomized clinical trial of hydroxymethylglutaryl-CoA reductase inhibition for acute lung injury (The HARP study)
-
Craig TR, Duffy MJ, Shyamsundar M, et al. A randomized clinical trial of hydroxymethylglutaryl-CoA reductase inhibition for acute lung injury (The HARP study). Am J Respir Crit Care Med 2011; 183:620-626.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 620-626
-
-
Craig, T.R.1
Duffy, M.J.2
Shyamsundar, M.3
-
45
-
-
63249128249
-
Intensive versus conventional glucose control in critically ill patients
-
Finfer S, Chittock DR, Su SY, et al. Intensive versus conventional glucose control in critically ill patients. N Engl J Med 2009; 360:1283-1297.
-
(2009)
N Engl J Med
, vol.360
, pp. 1283-1297
-
-
Finfer, S.1
Chittock, D.R.2
Su, S.Y.3
-
46
-
-
77649282276
-
Comparison of dopamine and norepinephrine in the treatment of shock
-
De Backer D, Biston P, Devriendt J, et al. Comparison of dopamine and norepinephrine in the treatment of shock. N Engl J Med 2010; 362:779-789.
-
(2010)
N Engl J Med
, vol.362
, pp. 779-789
-
-
De Backer, D.1
Biston, P.2
Devriendt, J.3
-
48
-
-
77950456427
-
Multiple personal genomes await
-
Venter JC. Multiple personal genomes await. Nature 2010; 464:676-677.
-
(2010)
Nature
, vol.464
, pp. 676-677
-
-
Venter, J.C.1
-
49
-
-
77950412216
-
The human genome at ten
-
The human genome at ten. Nature 2010; 464:649-650.
-
(2010)
Nature
, vol.464
, pp. 649-650
-
-
-
50
-
-
77951589703
-
Clinical assessment incorporating a personal genome
-
Ashley EA, Butte AJ, Wheeler MT, et al. Clinical assessment incorporating a personal genome. Lancet 2010; 375:1525-1535.
-
(2010)
Lancet
, vol.375
, pp. 1525-1535
-
-
Ashley, E.A.1
Butte, A.J.2
Wheeler, M.T.3
-
51
-
-
70249089090
-
Single-molecule sequencing of an individual human genome
-
Pushkarev D, Neff NF, Quake SR. Single-molecule sequencing of an individual human genome. Nat Biotechnol 2009; 27:847-850.
-
(2009)
Nat Biotechnol
, vol.27
, pp. 847-850
-
-
Pushkarev, D.1
Neff, N.F.2
Quake, S.R.3
-
52
-
-
73149123343
-
Genetic diagnosis by whole exome capture and massively parallel DNA sequencing
-
Choi M, Scholl UI, Ji W, et al. Genetic diagnosis by whole exome capture and massively parallel DNA sequencing. Proc Natl Acad Sci U S A 2009; 106:19096-19101.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 19096-19101
-
-
Choi, M.1
Scholl, U.I.2
Ji, W.3
-
53
-
-
77951547487
-
The personal genome: The future of personalised medicine?
-
Samani NJ, Tomaszewski M, Schunkert H. The personal genome: the future of personalised medicine? Lancet 2010; 375:1497-1498.
-
(2010)
Lancet
, vol.375
, pp. 1497-1498
-
-
Samani, N.J.1
Tomaszewski, M.2
Schunkert, H.3
-
54
-
-
33947712686
-
Stratified medicine: Strategic and economic implications of combining drugs and clinical biomarkers
-
DOI 10.1038/nrd2251, PII NRD2251
-
Trusheim MR, Berndt ER, Douglas FL. Stratified medicine: strategic and economic implications of combining drugs and clinical biomarkers. Nat Rev Drug Discov 2007; 6:287-293. (Pubitemid 46505879)
-
(2007)
Nature Reviews Drug Discovery
, vol.6
, Issue.4
, pp. 287-293
-
-
Trusheim, M.R.1
Berndt, E.R.2
Douglas, F.L.3
-
55
-
-
32144437063
-
The β-agonist lung injury trial (BALTI): A randomized placebo-controlled clinical trial
-
DOI 10.1164/rccm.200508-1302OC
-
Perkins GD, McAuley DF, Thickett DR, Gao F. The beta-agonist lung injury trial (BALTI): a randomized placebo-controlled clinical trial. Am J Respir Crit Care Med 2006; 173:281-287. (Pubitemid 43209082)
-
(2006)
American Journal of Respiratory and Critical Care Medicine
, vol.173
, Issue.3
, pp. 281-287
-
-
Perkins, G.D.1
McAuley, D.F.2
Thickett, D.R.3
Gao, F.4
-
56
-
-
79955694326
-
Beta Agonist Lung Injury TrIal-2 (BALTI-2) trial protocol: A randomised, double-blind, placebo-controlled of intravenous infusion of salbutamol in the acute respiratory distress syndrome
-
Perkins GD, Gates S, Lamb SE, et al. Beta Agonist Lung Injury TrIal-2 (BALTI-2) trial protocol: a randomised, double-blind, placebo-controlled of intravenous infusion of salbutamol in the acute respiratory distress syndrome. Trials 2011; 12:113.
-
(2011)
Trials
, vol.12
, pp. 113
-
-
Perkins, G.D.1
Gates, S.2
Lamb, S.E.3
-
57
-
-
79960430979
-
Randomized, placebo-controlled clinical trial of an aerosolized beta-2 agonist for treatment of acute lung injury
-
Epub ahead of print
-
Matthay MA, Brower RG, Carson S, et al. Randomized, placebo-controlled clinical trial of an aerosolized beta-2 agonist for treatment of acute lung injury. Am J Respir Crit Care Med 2011. [Epub ahead of print]
-
(2011)
Am J Respir Crit Care Med
-
-
Matthay, M.A.1
Brower, R.G.2
Carson, S.3
-
58
-
-
77649252269
-
Visualization of omics data for systems biology
-
Gehlenborg N, O'Donoghue SI, Baliga NS, et al. Visualization of omics data for systems biology. Nat Methods 2010; 7 (3 Suppl):S56-S68.
-
(2010)
Nat Methods
, vol.7
, Issue.3 SUPPL.
-
-
Gehlenborg, N.1
O'donoghue, S.I.2
Baliga, N.S.3
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