Alterations in glycopeptides associated with herceptin treatment of human breast carcinoma MCF-7 and T-lymphoblastoid cells

Molecular and Cellular Proteomics

Volumn 10, Issue 9, 2011, Pages

  Lattová, Erika ^a,b   Bartusik, Dorota ^c,d   Spicer, Vic ^a   Jellusova, Julia ^e   Perreault, Hélène ^a   Tomanek, Boguslaw ^c,f  

^a UNIVERSITY OF MANITOBA   (Canada)

^b INSTITUTE OF CHEMISTRY   (Slovakia)

^c NATIONAL RESEARCH COUNCIL CANADA   (Canada)

^d CROSS CANCER INSTITUTE   (Canada)

^e BURNHAM INSTITUTE   (United States)

^f UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPEPTIDE; TRASTUZUMAB; ANTINEOPLASTIC AGENT; LIPID; LIPOFECTAMINE; MONOCLONAL ANTIBODY; TRYPSIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER GROWTH; CELL STRAIN MCF 7; CELL VIABILITY; HUMAN; HUMAN CELL; LYMPHOBLASTOID CELL; PRIORITY JOURNAL; PROTEIN GLYCOSYLATION; PROTEIN PROCESSING; T LYMPHOBLASTOID CELL; TANDEM MASS SPECTROMETRY; ACUTE LYMPHOBLASTIC LEUKEMIA; BREAST TUMOR; CARBOHYDRATE ANALYSIS; CELL SURVIVAL; CHEMISTRY; DRUG EFFECT; DRUG RESISTANCE; FEMALE; GENETIC TRANSFECTION; GENETICS; GLYCOBIOLOGY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PATHOLOGY; PLASMID; PROTEOMICS; TUMOR CELL LINE;

ANTIBODIES, MONOCLONAL, HUMANIZED; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CARBOHYDRATE SEQUENCE; CELL LINE, TUMOR; CELL SURVIVAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG RESISTANCE, NEOPLASM; FEMALE; GLYCOMICS; GLYCOPEPTIDES; HUMANS; LIPIDS; MOLECULAR SEQUENCE DATA; PLASMIDS; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TRANSFECTION; TRYPSIN;

EID: 80052770403     PISSN: 15359476     EISSN: 15359484     Source Type: Journal    
DOI: 10.1074/mcp.M111.007765     Document Type: Article

References (40)

1. Bertozzi, C. R., and Kiessling, L. L. (2001) Chemical glycobiology. Science 291, 2357-2364 (Pubitemid 32231790)
2. Ogata, S., Ho, I., Chen, A., Dubois, D., Maklansky, J., Singhal, A., Hakomori, S., and Itzkowitz, S. H. (1995) Tumor-associated sialylated antigens are constitutively expressed in normal human colonic mucosa. Cancer Res. 55, 1869-1874
3. Danishefsky, S. J., and Allen, J. R. (2000) From the laboratory to the clinic: a retrospective on fully synthetic carbohydrate-based anticancer vaccines frequently used abbreviations are listed in the appendix. Angew. Chem. Int. Ed. Engl. 39, 836-863 (Pubitemid 30217267)
4. Parodi, A. J. (2000) Protein glucosylation and its role in protein folding. Annu. Rev. Biochem. 69, 69-93
5. Walsh, G., and Jefferis, R. (2006) Post-translational modifications in the context of therapeutic proteins. Nat. Biotechnol. 24, 1241-1252 (Pubitemid 44564769)
6. Kanda, Y., Yamada, T., Mori, K., Okazaki, A., Inoue, M., Kitajima-Miyama, K., Kuni-Kamochi, R., Nakano, R., Yano, K., Kakita, S., Shitara, K., and Satoh, M. (2007) Comparison of biological activity among nonfucosylated therapeutic igg1 antibodies with three different n-linked fc oligosaccharides: the high-mannose, hybrid, and complex types. Glycobiology 17, 104-118 (Pubitemid 44932818)
7. Suzuki, E., Niwa, R., Saji, S., Muta, M., Hirose, M., Iida, S., Shiotsu, Y., Satoh, M., Shitara, K., Kondo, M., and Toi, M. (2007) A nonfucosylated anti-her2 antibody augments antibody-dependent cellular cytotoxicity in breast cancer patients. Clin. Cancer Res. 13, 1875-1882 (Pubitemid 46952958)
8. Jefferis, R. (2009) Recombinant antibody therapeutics: the impact of glycosylation on mechanisms of action. Trends Pharmacol. Sci. 30, 356-362
9. Jefferis, R. (2005) Glycosylation of recombinant antibody therapeutics. Biotechnol. Prog. 21, 11-16
10. Kamoda, S., Nomura, C., Kinoshita, M., Nishiura, S., Ishikawa, R., Kakehi, K., Kawasaki, N., and Hayakawa, T. (2004) Profiling analysis of oligosaccharides in antibody pharmaceuticals by capillary electrophoresis. J Chromatogr A 1050, 211-216 (Pubitemid 39286246)
11. Jefferis, R. (2009) Glycosylation of antibody therapeutics: optimisation for purpose. Methods Mol. Biol. 483, 223-238
12. Slamon, D. J., Leyland-Jones, B., Shak, S., Fuchs, H., Paton, V., Bajamonde, A., Fleming, T., Eiermann, W., Wolter, J., Pegram, M., Baselga, J., and Norton, L. (2001) Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses her2. N. Engl. J. Med. 344, 783-792 (Pubitemid 32222155)
13. Müller, M. R., Grünebach, F., Kayser, K., Vogel, W., Nencioni, A., Brugger, W., Kanz, L., and Brossart, P. (2003) Expression of her-2/neu on acute lymphoblastic leukemias: implications for the development of immunotherapeutic approaches. Clin. Cancer Res. 9, 3448-3453 (Pubitemid 37082743)
14. Musolino, A., Naldi, N., Bortesi, B., Pezzuolo, D., Capelletti, M., Missale, G., Laccabue, D., Zerbini, A., Camisa, R., Bisagni, G., Neri, T. M., and Ardizzoni, A. (2008) Immunoglobulin g fragment c receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with her-2/neu-positive metastatic breast cancer. J. Clin. Oncol. 26, 1789-1796
15. Jones, A. (2003) Combining trastuzumab (herceptin) with hormonal therapy in breast cancer: what can be expected and why?. Ann. Oncol. 14, 1697-1704
16. Romond, E. H., Perez, E. A., Bryant, J., Suman, V. J., Geyer, C. E., Jr, Davidson, N. E., Tan-Chiu, E., Martino, S., Paik, S., Kaufman, P. A., Swain, S. M., Pisansky, T. M., Fehrenbacher, L., Kutteh, L. A., Vogel, V. G., Visscher, D. W., Yothers, G., Jenkins, R. B., Brown, A. M., Dakhil, S. R., Mamounas, E. P., Lingle, W. L., Klein, P. M., Ingle, J. N., and Wolmark, N. (2005) Trastuzumab plus adjuvant chemotherapy for operable her2-positive breast cancer. N. Engl. J. Med. 353, 1673-1684 (Pubitemid 41464706)
17. Arnould, L., Gelly, M., Penault-Llorca, F., Benoit, L., Bonnetain, F., Migeon, C., Cabaret, V., Fermeaux, V., Bertheau, P., Garnier, J., Jeannin, J. F., and Coudert, B. (2006) Trastuzumab-based treatment of her2-positive breast cancer: an antibody-dependent cellular cytotoxicity mechanism? Br. J. Cancer 94, 259-267 (Pubitemid 43151545)
18. Toi, M., Horiguchi, K., Bando, H., Saji, S., and Chow, L. W. C. (2005) Trastuzumab: updates and future issues. Cancer Chemother. Pharmacol. 56 Suppl 1, 94-99
19. Lattová, E., Tomanek, B., Bartusik, D., and Perreault, H. (2010) N-glycomic changes in human breast carcinoma mcf-7 and t-lymphoblastoid cells after treatment with herceptin and herceptin/lipoplex. J. Proteome Res. 9, 1533-1540
20. Håkansson, K., Cooper, H. J., Emmett, M. R., Costello, C. E., Marshall, A. G., and Nilsson, C. L. (2001) Electron capture dissociation and infrared multiphoton dissociation ms/ms of an n-glycosylated tryptic peptic to yield complementary sequence information. Anal. Chem. 73, 4530-4536 (Pubitemid 32868256)
21. Lattová, E., Kapková, P., Krokhin, O., and Perreault, H. (2006) Method for investigation of oligosaccharides from glycopeptides: direct determination of glycosylation sites in proteins. Anal. Chem. 78, 2977-2984 (Pubitemid 43726115)
22. Go, E. P., Rebecchi, K. R., Dalpathado, D. S., Bandu, M. L., Zhang, Y., and Desaire, H. (2007) Glycopep db: a tool for glycopeptide analysis using a "smart search". Anal. Chem. 79, 1708-1713
23. Carapito, C., Klemm, C., Aebersold, R., and Domon, B. (2009) Systematic lc-ms analysis of labile post-translational modifications in complex mixtures. J. Proteome Res. 8, 2608-2614
24. Tzur, Y., Markovich, A., and Lichtenstein, R. G. (2008) A two-dimensional array for simultaneous sequencing of n- and o-glycans and their glycoforms on specific glycosylation sites. J. Proteome Res. 7, 1188-1198
25. Gong, B., Cukan, M., Fisher, R., Li, H., Stadheim, T. A., and Gerngross, T. (2009) Characterization of n-linked glycosylation on recombinant glycoproteins produced in pichia pastoris using esi-ms and maldi-tof. Methods Mol. Biol. 534, 213-223
26. Dodds, E. D., Seipert, R. R., Clowers, B. H., German, J. B., and Lebrilla, C. B. (2009) Analytical performance of immobilized pronase for glycopeptide footprinting and implications for surpassing reductionist glycoproteomics. J. Proteome Res. 8, 502-512
27. Balog, C. I., Mayboroda, O. A., Wuhrer, M., Hokke, C. H., Deelder, A. M., and Hensbergen, P. J. (2010) Mass spectrometric identification of aberrantly glycosylated human apolipoprotein c-iii peptides in urine from schistosoma mansoni-infected individuals. Mol. Cell Proteomics 9, 667-681
28. Scott, N. E., Parker, B. L., Connolly, A. M., Paulech, J., Edwards, A. V. G., Crossett, B., Falconer, L., Kolarich, D., Djordjevic, S. P., Højrup, P., Packer, N. H., Larsen, M. R., and Cordwell, S. J. (2011) Simultaneous glycan-peptide characterization using hydrophilic interaction chromatography and parallel fragmentation by cid, higher energy collisional dissociation, and electron transfer dissociation ms applied to the nlinked glycoproteome of campylobacter jejuni. Mol. Cell Proteomics 10, M000031MCP201
29. Bartusik, D., Tomanek, B., Lattová, E., Perreault, H., and Fallone, G. (2010) Combined treatment of human mcf-7 breast carcinoma with antibody, cationic lipid and hyaluronic acid using ex vivo assays. J Pharm Biomed Anal 51, 192-201
30. Bartusik, D., Tomanek, B., Lattová, E., Perreault, H., and Fallone, G. (2010) Ex vivo assays of cem cells cultured and treated in the three dimensional cultures. Biomed. Pharmacother. 64, 390-395
31. Turk, T. M., Rees, M. A., Pietrow, P., Myers, C. E., Mills, S. E., and Gillenwater, J. Y. (1999) Determination of optimal freezing parameters of human prostate cancer in a nude mouse model. Prostate 38, 137-143 (Pubitemid 29052952)
32. Lattová, E., McKenzie, E. J., Gruwel, M. L., Spicer, V., Goldman, R., and Perreault, H. (2009) Mass spectrometric study of n-glycans from serum of woodchucks with liver cancer. Rapid Commun. Mass Spectrom. 23, 2983-2995
33. Loboda, A. V., Krutchinsky, A. N., Bromirski, M., Ens, W., and Standing, K. G. (2000) A tandem quadrupole/time-of-flight mass spectrometer with a matrix-assisted laser desorption/ionization source: design and performance. Rapid Commun. Mass Spectrom. 14, 1047-1057 (Pubitemid 30409412)
34. Roepstorff, P., and Fohlman, J. (1984) Proposal for a common nomenclature for sequence ions in mass spectra of peptides. Biomed. Mass Spectrom. 11, 601
35. Lattová, E., Chen, V. C., Varma, S., Bezabeh, T., and Perreault, H. (2007) Matrix-assisted laser desorption/ionization on-target method for the investigation of oligosaccharides and glycosylation sites in glycopeptides and glycoproteins. Rapid Commun. Mass Spectrom. 21, 1644-1650 (Pubitemid 46827113)
36. Lattova, E., Perreault, H., and Krokhin, O. (2004) Matrix-assisted laser desorption/ionization tandem mass spectrometry and post-source decay fragmentation study of phenylhydrazones of n-linked oligosaccharides from ovalbumin. J. Am. Soc. Mass Spectrom. 15, 725-735 (Pubitemid 38581099)
37. Damen, C. W., Chen, W., Chakraborty, A. B., Van Oosterhout, M., Mazzeo, J. R., Gebler, J. C., Schellens, J. H., Rosing, H., and Beijnen, J. H. (2009) Electrospray ionization quadrupole ion-mobility time-of-flight mass spectrometry as a tool to distinguish the lot-to-lot heterogeneity in n-glycosylation profile of the therapeutic monoclonal antibody trastuzumab. J. Am. Soc. Mass Spectrom. 20, 2021-2033
38. Stadlmann, J., Pabst, M., Kolarich, D., Kunert, R., and Altmann, F. (2008) Analysis of immunoglobulin glycosylation by lc-esi-ms of glycopeptides and oligosaccharides. Proteomics 8, 2858-2871
39. Pirollo, K. F., Xu, L., and Chang, E. H. (2000) Non-viral gene delivery for p53. Curr. Opin. Mol. Ther. 2, 168-175 (Pubitemid 30212266)
40. Jones, A. J., Papac, D. I., Chin, E. H., Keck, R., Baughman, S. A., Lin, Y. S., Kneer, J., and Battersby, J. E. (2007) Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal n-acetylglucosamine is similar in humans and cynomolgus monkeys. Glycobiology 17, 529-540 (Pubitemid 47049940)