Antithrombotic medication for cardioembolic stroke prevention

Stroke Research and Treatment

Volumn , Issue , 2011, Pages

  Font, M Ángels ^a,b   Krupinski, Jerzy ^c   Arboix, Adri ^d  

^a HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^b Hospital Sant Joan de Déu de Manresa   (Spain)

^c HOSPITAL MÚTUA DE TERRASSA   (Spain)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTICOAGULANT AGENT; ANTIVITAMIN K; APIXABAN; BLOOD CLOTTING FACTOR 10A INHIBITOR; CERTOPARIN; CLOPIDOGREL; DABIGATRAN; DABIGATRAN ETEXILATE; DALTEPARIN; DANAPAROID; DIPYRIDAMOLE; EDOXABAN; ENOXAPARIN; HEPARINOID; IDRAPARINUX; INDOBUFEN; IRBESARTAN; NADROPARIN; PLACEBO; RIVAROXABAN; TECARFARIN; TINZAPARIN; WARFARIN; XIMELAGATRAN;

ACUTE HEART INFARCTION; ALCOHOL ABUSE; ANTICOAGULATION; AORTA STENOSIS; BACTERIAL ENDOCARDITIS; BLEEDING; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; CORONARY ARTERY DISEASE; DIABETES MELLITUS; DRUG DOSE INCREASE; EMBOLISM; HEART ATRIUM FIBRILLATION; HEART CATHETERIZATION; HEART TRANSPLANTATION; HEART VALVE PROSTHESIS; HUMAN; INTERNATIONAL NORMALIZED RATIO; KIDNEY DISEASE; LIVER TOXICITY; LOW DRUG DOSE; LUNG ADENOCARCINOMA; MITRAL VALVE DISEASE; MITRAL VALVE PROLAPSE; MORTALITY; PATENT FORAMEN OVALE; PREVALENCE; PRIORITY JOURNAL; REVIEW; RHEUMATIC HEART DISEASE; STROKE; SYSTEMATIC REVIEW; SYSTOLIC HYPERTENSION; THROMBOEMBOLISM; TRANSIENT GLOBAL AMNESIA; TRANSIENT ISCHEMIC ATTACK;

EID: 80052767106     PISSN: None     EISSN: 20420056     Source Type: Journal    
DOI: 10.4061/2011/607852     Document Type: Review

References (229)

1. Sacco R. L., Adams R., Albers G., Alberts M. J., Benavente O., Furie K., Goldstein L. B., Gorelick P., Halperin J., Harbaugh R., Johnston S. C., Katzan I., Kelly-Hayes M., Kenton E. J., Marks M., Schwamm L. H., Tomsick T., Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline Stroke 2006 37 2 577 617 (Pubitemid 43732031)
2. Amarenco P., Cohen A., Tzourio C., Bertrand B., Hommel M., Besson G., Chauvel C., Touboul P. J., Bousser M. G., Atherosclerotic disease of the aortic arch and the risk of ischemic stroke New England Journal of Medicine 1994 331 22 1474 1479 (Pubitemid 24356305)
3. Arboix A., Mart-Vilalta J. L., Presumed cardioembolic lacunar infarcts Stroke 1992 23 12 1841 1842
4. Lodder J., Bamford J. M., Sandercock P. A. G., Jones L. N., Warlow C. P., Are hypertension or cardiac embolism likely causes of lacunar infarction? Stroke 1990 21 3 375 381 (Pubitemid 20089780)
5. Fisher C. M., Capsular infarcts: the underlying vascular lesions Archives of Neurology 1979 36 2 65 73 (Pubitemid 9083182)
6. Guidelines for management of ischaemic stroke and transient ischaemic attack 2008 Cerebrovascular Diseases 2008 25 5 457 507
7. Cervera A., Amaro S., Obach V., Chamorro A., Prevention of ischemic stroke: antithrombotic therapy in cardiac embolism Current Drug Targets 2007 8 7 824 831 (Pubitemid 47163392)
8. Whitlon D. S., Sadowski J. A., Suttie J. W., Mechanism of coumarin action: significance of vitamin K epoxide reductase inhibition Biochemistry 1978 17 8 1371 1377 (Pubitemid 8330368)
9. Schulman S., Beyth R. J., Kearon C., Levine M. N., Hemorrhagic complications of anticoagulant and thrombolytic treatment: American College of Chest Physicians evidence-based clinical practice guidelines (8th edition) Chest 2008 133 supplement 6 257S 298S (Pubitemid 351892969)
10. Fuster V., Rydén L. E., Cannom D. S., Crijns H. J., Curtis A. B., Ellenbogen K. A., Halperin J. L., Le Heuzey J. Y., Kay G. N., Lowe J. E., Olsson S. B., Prystowsky E. N., Tamargo J. L., Wann S., Smith S. C., Jacobs A. K., Adams C. D., Anderson J. L., Antman E. M., Halperin J. L., Hunt S. A., Nishimura R., Ornato J. P., Page R. L., Riegel B., Priori S. G., Blanc J. J., Budaj A., Camm A. J., Dean V., Deckers J. W., Despres C., Dickstein K., Lekakis J., McGregor K., Metra M., Morais J., Osterspey A., Tamargo J. L., Zamorano J. L., ACC/AHA/ESC 2006 guidelines for the management of patients with atrial fibrillationexecutive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management of Patients With Atrial Fibrillation) Journal of the American College of Cardiology 2006 48 4 854 906 (Pubitemid 44175743)
11. Go A. S., Hylek E. M., Phillips K. A., Chang Y. C., Henault L. E., Selby J. V., Singer D. E., Prevalence of diagnosed atrial fibrillation in adults: national implications for rhythm management and stroke prevention: the anticoagulation and risk factors in atrial fibrillation (ATRIA) study Journal of the American Medical Association 2001 285 18 2370 2375 (Pubitemid 32424106)
12. Anderson D. C., Kappelle L. J., Eliasziw M., Babikian V. L., Pearce L. A., Barnett H. J. M., Occurrence of hemispheric and retinal ischemia in atrial fibrillation compared with carotid stenosis Stroke 2002 33 8 1963 1967 (Pubitemid 34840050)
13. Hart R. G., Benavente O., McBride R., Pearce L. A., Antithrombotic therapy to prevent stroke in patients with atrial fibrillation: a meta-analysis Annals of Internal Medicine 1999 131 7 492 501 (Pubitemid 29482392)
14. Lip G. Y. H., Edwards S. J., Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: a systematic review and meta-analysis Thrombosis Research 2006 118 3 321 333 (Pubitemid 44067199)
15. Singer D. E., Albers G. W., Dalen J. E., Go A. S., Halperin J. L., Manning W. J., Antithrombotic therapy in atrial fibrillation: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest 2004 126 supplement 3 429S 456S (Pubitemid 39302603)
16. Wolf P. A., Dawber T. R., Thomas H. E. Jr., Kannel W. B., Epidemiologic assessment of chronic atrial fibrillation and risk of stroke: the Framingham study Neurology 1978 28 10 973 977 (Pubitemid 8401525)
17. Atrial Fibrillation Investigators, Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials Archives of Internal Medicine 1994 154 13 1449 1457
18. European Atrial Fibrillation Trial Study Group, Secondary prevention in non-rheumatic atrial fibrillation after transient ischaemic attack or minor stroke Lancet 1993 342 8882 1255 1262
19. Atrial Fibrillation Investigators, Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation: analysis of pooled data from five randomized controlled trials Archives of Internal Medicine 1994 154 13 1449 1457
20. The efficacy of aspirin in patients with atrial fibrillation. Analysis of pooled data from 3 randomized trials. The atrial fibrillation investigators Archives of Internal Medicine 1997 157 11 1237 1240
21. Albers G. W., Atrial fibrillation and stroke: three new studies, three remaining questions Archives of Internal Medicine 1994 154 13 1443 1448 (Pubitemid 24208569)
22. Van Walraven C., Hart R. G., Singer D. E., Laupacis A., Connolly S., Petersen P., Koudstaal P. J., Chang Y., Hellemons B., Oral anticoagulants vs aspirin in nonvalvular atrial fibrillation: an individual patient meta-analysis Journal of the American Medical Association 2002 288 19 2441 2448 (Pubitemid 35340540)
23. Stroke Prevention in Atrial Fibrillation Investigators, Risk factors for thromboembolism during aspirin therapy in patients with atrial fibrillation: the stroke prevention in atrial fibrillation study Journal of Stroke and Cerebrovascular Diseases 1995 5 3 147 157
24. Stroke Prevention in Atrial Fibrillation Investigators, Adjusted-dose warfarin versus low-intensity, fixed-dose warfarin plus aspirin for high-risk patients with atrial fibrillation: stroke prevention in atrial fibrillation III randomized clinical trial Lancet 1996 348 9028 633 638
25. Dentali F., Douketis J. D., Lim W., Crowther M., Combined aspirin-oral anticoagulant therapy compared with oral anticoagulant therapy alone among patients at risk for cardiovascular disease: a meta-analysis of randomized trials Archives of Internal Medicine 2007 167 2 117 124 (Pubitemid 46148058)
26. The SPAF III Writing Committee for the Stroke Prevention in Atrial Fibrillation Investigators, Patients with nonvalvular atrial fibrillation at low risk of stroke during treatment with aspirin: Stroke Prevention in Atrial Fibrillation III Study Journal of the American Medical Association 1998 279 16 1237 1277
27. ACTIVE Investigators, Clopidogrel plus aspirin versus oral anticoagulation for atrial fibrillation in the Atrial fibrillation Clopidogrel Trial with Irbesartan for Prevention of Vascular Events (ACTIVE W): a randomised controlled trial Lancet 2006 367 9526 1903 1912
28. Connolly S. J., Pogue J., Hart R. G., Hohnloser S. H., Pfeffer M., Chrolavicius S., Yusuf S., Effect of clopidogrel added to aspirin in patients with atrial fibrillation New England Journal of Medicine 2009 360 20 2066 2078
29. Gage B. F., Waterman A. D., Shannon W., Boechler M., Rich M. W., Radford M. J., Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation Journal of the American Medical Association 2001 285 22 2864 2870 (Pubitemid 32537350)
30. Wang T. J., Massaro J. M., Levy D., Vasan R. S., Wolf P. A., D'Agostino R. B., Larson M. G., Kannel W. B., Benjamin E. J., A risk score for predicting stroke or death in individuals with new-onset atrial fibrillation in the community: the Framingham Heart Study Journal of the American Medical Association 2003 290 8 1049 1056 (Pubitemid 37430445)
31. Stroke Risk in Atrial Fibrillation Working Group, Independent predictors of stroke in patients with atrial fibrillation: a systematic review Neurology 2007 69 6 546 554
32. Jarquin-Valdivia A. A., Wijdicks E. F., McGregor C., Neurologic complications following heart transplantation in the modern era: decreased incidence, but postoperative stroke remains prevalent Transplantation Proceedings 1999 31 5 2161 2162 (Pubitemid 29376558)
33. Belvs R., Mart-Fbregas J., Cocho D., Garca-Bargo M. D., Franquet E., Agudo R., Brosa V., Camprecis M., Puig M., Mart-Vilalta J. L., Cerebrovascular disease as a complication of cardiac transplantation Cerebrovascular Diseases 2005 19 4 267 271 (Pubitemid 40591495)
34. Ricotta J. J., Faggioli G. L., Castilone A., Hassett J. M., Risk factors for stroke after cardiac surgery: Buffalo Cardiac-Cerebral Study Group Journal of Vascular Surgery 1995 21 2 359 364
35. Gage B. F., Yan Y., Milligan P. E., Waterman A. D., Culverhouse R., Rich M. W., Radford M. J., Clinical classification schemes for predicting hemorrhage: results from the National Registry of Atrial Fibrillation (NRAF) American Heart Journal 2006 151 3 713 719 (Pubitemid 43290267)
36. Hylek E. M., Singer D. E., Risk factors for intracranial hemorrhage in outpatients taking warfarin Annals of Internal Medicine 1994 120 11 897 902 (Pubitemid 24179151)
37. Goldstein L. B., Adams R., Alberts M. J., Appel L. J., Brass L. M., Bushnell C. D., Culebras A., DeGraba T. J., Gorelick P. B., Guyton J. R., Hart R. G., Howard G., Kelly-Hayes M., Nixon J. V., Sacco R. L., Primary prevention of ischemic stroke: a guideline from the American Heart Association/American Stroke Association Stroke Council: cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: the American Academy of Neurology affirms the value of this guideline Stroke 2006 37 6 1583 1633 (Pubitemid 44313592)
38. Hylek E. M., Skates S. J., Sheehan M. A., Singer D. E., An analysis of the lowest effective intensity of prophylactic anticoagulation for patients with nonrheumatic atrial fibrillation New England Journal of Medicine 1996 335 8 540 546 (Pubitemid 26272308)
39. Samsa G. P., Matchar D. B., Goldstein L. B., Bonito A. J., Lux L. J., Witter D. M., Bian J., Quality of anticoagulation management among patients with atrial fibrillation: results of a review of medical records from 2 communities Archives of Internal Medicine 2000 160 7 967 973 (Pubitemid 30191925)
40. Bungard T. J., Ackman M. L., Ho G., Tsuyuki R. T., Adequacy of anticoagulation in patients with atrial fibrillation coming to a hospital Pharmacotherapy 2000 20 9 1060 1065
41. Gage B. F., Van Walraven C., Pearce L., Hart R. G., Koudstaal P. J., Boode B. S. P., Petersen P., Selecting patients with atrial fibrillation for anticoagulation: stroke risk stratification in patients taking aspirin Circulation 2004 110 16 2287 2292 (Pubitemid 39407328)
42. Kalra L., Lip G. Y., Guideline Development Group for the NICE clinical guideline for the management of atrial fibrillation. Antithrombotic treatment in atrial fibrillation Heart 2007 93 1 39 44
43. The Atrial Fibrillation Followup Investigation of Rhythm Management Investigators, A comparison of rate control and rhythm control in patients with atrial fibrillation New England Journal of Medicine 2002 347 23 1825 1833
44. Hylek E. M., Go A. S., Chang Y., Jensvold N. G., Henault L. E., Selby J. V., Singer D. E., Effect of intensity of oral anticoagulation on stroke severity and mortality in atrial fibrillation New England Journal of Medicine 2003 349 11 1019 1026 (Pubitemid 37087616)
45. Rash A., Downes T., Portner R., Yeo W. W., Morgan N., Channer K. S., A randomised controlled trial of warfarin versus aspirin for stroke prevention in octogenarians with atrial fibrillation (WASPO) Age and Ageing 2007 36 2 151 156 (Pubitemid 46455393)
46. Mant J., Hobbs F. D., Fletcher K., Roalfe A., Fitzmaurice D., Lip G. Y., Murray E., Warfarin versus aspirin for stroke prevention in an elderly community population with atrial fibrillation (the Birmingham Atrial Fibrillation Treatment of the Aged Study, BAFTA): a randomised controlled trial Lancet 2007 370 9586 493 503 (Pubitemid 47212371)
47. Herlitz J., Holm J., Peterson M., Karlson B. W., Evander M. H., Erhardt L., Factors associated with development of stroke long-term after myocardial infarction: experiences from the LoWASA trial Journal of Internal Medicine 2005 257 2 201 207 (Pubitemid 40193970)
48. Behar S., Tanne D., Abinader E., Agmon J., Barzilai J., Friedman Y., Kaplinsky E., Kauli N., Kishon Y., Palant A., Peled B., Reisin L., Schlesinger Z., Zahavi I., Zion M., Goldbourt U., Cerebrovascular accident complicating acute myocardial infarction: incidence, clinical significance, and short- and long-term mortality rates. The SPRINT Study Group American Journal of Medicine 1991 91 1 45 50
49. Sloan M. A., Price T. R., Terrin M. L., Forman S., Gore J. M., Chaitman B. R., Hodges M., Mueller H., Rogers W. J., Knatterud G. L., Braunwald E., Ischemic cerebral infarction after rt-PA and heparin therapy for acute myocardial infarction: the TIMI-II pilot and randomized clinical trial combined experience Stroke 1997 28 6 1107 1114 (Pubitemid 27248879)
50. Kassem-Moussa H., Mahaffey K. W., Graffagnino C., Tasissa G., Sila C. A., Simes R. J., White H. D., Califf R. M., Bhapkar M. V., Newby L. K., Incidence and characteristics of stroke during 90-day follow-up in patients stabilized after an acute coronary syndrome American Heart Journal 2004 148 3 439 446 (Pubitemid 39265116)
51. Saczynski J. S., Spencer F. A., Gore J. M., Gurwitz J. H., Yarzebski J., Lessard D., Goldberg R. J., Twenty-year trends in the incidence of stroke complicating acute myocardial infarction: Worcester Heart Attack Study Archives of Internal Medicine 2008 168 19 2104 2110
52. Witt B. J., Brown R. D. Jr., Jacobsen S. J., Weston S. A., Yawn B. P., Roger V. L., A community-based study of stroke incidence after myocardial infarction Annals of Internal Medicine 2005 143 11 785 792
53. Mooe T., Olofsson B. O., Stegmayr B., Eriksson P., Ischemic stroke: impact of a recent myocardial infarction Stroke 1999 30 5 997 1001 (Pubitemid 29211617)
54. Nadareishvili Z. G., Choudary Z., Joyner C., Brodie D., Norris J. W., Cerebral microembolism in acute myocardial infarction Stroke 1999 30 12 2679 2682
55. Loh E., Sutton M. S., Wun C. C., Rouleau J. L., Flaker G. C., Gottlieb S. S., Lamas G. A., Moyé L. A., Goldhaber S. Z., Pfeffer M. A., Ventricular dysfunction and the risk of stroke after myocardial infarction New England Journal of Medicine 1997 336 4 251 257 (Pubitemid 27044626)
56. Anonymous, ISIS-3: a randomised comparison of streptokinase vs tissue plasminogen activator vs anistreplase and of aspirin plus heparin vs aspirin alone among 41,299 cases of suspected acute myocardial infarction. ISIS-3 (Third International Study of Infarct Survival) Collaborative Group Lancet 1992 339 8796 753 770
57. Maggioni A. P., Franzosi M. G., Santoro E., The risk of stroke in patients with acute myocardial infarction after thrombolytic and antithrombotic treatment. Gruppo Italiano per lo Studio della Sopravvivenza nell'Infarto Miocardico II (GISSI-2), and the International Study Group New England Journal of Medicine 1992 327 1 1 6
58. Anonymous, An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO investigators New England Journal of Medicine 1993 329 10 673 682
59. Van de Graaff E., Dutta M., Das P., Shry E. A., Frederick P. D., Blaney M., Pasta D. J., Steinhubl S. R., Early coronary revascularization diminishes the risk of ischemic stroke with acute myocardial infarction Stroke 2006 37 10 2546 2551 (Pubitemid 44454677)
60. Anonymous, Randomised trial of intravenous streptokinase, oral aspirin, both, or neither among 17,187 cases of suspected acute myocardial infarction: ISIS-2. ISIS-2 (Second International Study of Infarct Survival) Collaborative Group Lancet 1988 2 8607 349 360
61. Azar A. J., Koudstaal P. J., Wintzen A. R., Van Bergen P. F., Jonker J. J., Deckers J. W., Risk of stroke during long-term anticoagulant therapy in patients after myocardial infarction Annals of Neurology 1996 39 3 301 307 (Pubitemid 26100753)
62. Fiore L. D., Ezekowitz M. D., Brophy M. T., Lu D., Sacco J., Peduzzi P., Department of veterans affairs cooperative studies program clinical trial comparing combined warfarin and aspirin with aspirin alone in survivors of acute myocardial infarction: primary results of the CHAMP study Circulation 2002 105 5 557 563 (Pubitemid 34123428)
63. Hurlen M., Abdelnoor M., Smith P., Erikssen J., Arnesen H., Warfarin, aspirin, or both after myocardial infarction New England Journal of Medicine 2002 347 13 969 974
64. Van Es R. F., Jonker J. J., Verheugt F. W., Deckers J. W., Grobbee D. E., Aspirin and coumadin after acute coronary syndromes (the ASPECT-2 study): a randomised controlled trial Lancet 2002 360 9327 109 113 (Pubitemid 34786198)
65. Visser C. A., Kan G., Meltzer R. S., Lie K. I., Durrer D., Long-term follow-up of left ventricular thrombus after acute myocardial infarction. A two-dimensional echocardiographic study in 96 patients Chest 1984 86 4 532 536 (Pubitemid 14011177)
66. Huynh T., Cox J. L., Massel D., Davies C., Hilbe J., Warnica W., Daly P. A., Predictors of intracranial hemorrhage with fibrinolytic therapy in unselected community patients: a report from the FASTRAK II project American Heart Journal 2004 148 1 86 91 (Pubitemid 38900484)
67. Massie B. M., Shah N. B., Evolving trends in the epidemiologic factors of heart failure: rationale for preventive strategies and comprehensive disease management American Heart Journal 1997 133 6 703 712 (Pubitemid 27287220)
68. Katz S. D., Marantz P. R., Biasucci L., Jondeau G., Lee K., Brennan C., LeJemtel T. H., Low incidence of stroke in ambulatory patients with heart failure: a prospective study American Heart Journal 1993 126 1 141 146 (Pubitemid 23201585)
69. Fuster V., Gersh B. J., Giuliani E. R., Tajik A. J., Brandenburg R. O., Frye R. L., The natural history of idiopathic dilated cardiomyopathy American Journal of Cardiology 1981 47 3 525 531 (Pubitemid 11137647)
70. Vaitkus P. T., Barnathan E. S., Embolic potential, prevention and management of mural thrombus complicating anterior myocardial infarction: a meta-analysis Journal of the American College of Cardiology 1993 22 4 1004 1009 (Pubitemid 23285748)
71. Petersen P., Boysen G., Godtfredsen J., Andersen E. D., Andersen B., Placebo-controlled, randomised trial of warfarin and aspirin for prevention of thromboembolic complications in chronic atrial fibrillation. The Copenhagen AFASAK study Lancet 1989 1 8631 175 179 (Pubitemid 19038801)
72. Dries D. L., Domanski M. J., Waclawiw M. A., Gersh B. J., Effect of antithrombotic therapy on risk of sudden coronary death in patients with congestive heart failure American Journal of Cardiology 1997 79 7 909 913 (Pubitemid 27197925)
73. Pullicino P., Thompson J. L., Barton B., Levin B., Graham S., Freudenberger R. S., Warfarin versus aspirin in patients with reduced cardiac ejection fraction (WARCEF): rationale, objectives, and design Journal of Cardiac Failure 2006 12 1 39 46 (Pubitemid 43267750)
74. Coulshed N., Epstein E. J., McKendrick C. S., Galloway R. W., Walker E., Systemic embolism in mitral valve disease British Heart Journal 1970 32 1 26 34
75. Wood P., An appreciation of mitral stenosis. I. Clinical features British Medical Journal 1954 1 4870 1051 1063
76. Rowe J. C., Bland E. F., Sprague H. B., White P. D., The course of mitral stenosis without surgery: ten- and twenty-year perspectives Annals of Internal Medicine 1960 52 741 749
77. Abernathy W. S., Willis P. W. III, Thromboembolic complications of rheumatic heart disease Cardiovascular Clinics 1973 5 2 131 175
78. Daley R., Mattingly T. W., Holt C. L., Bland E. F., White P. D., Systemic arterial embolism in rheumatic heart disease American Heart Journal 1951 42 4 566 581
79. Adams G. F., Merrett J. D., Hutchinson W. M., Pollock A. M., Cerebral embolism and mitral stenosis: survival with and without anticoagulants Journal of Neurology Neurosurgery and Psychiatry 1974 37 4 378 383
80. Stroke Prevention in Atrial Fibrillation Study: final results Circulation 1991 84 2 527 539
81. Ezekowitz M. D., Bridgers S. L., James K. E., Carliner N. H., Colling C. L., Gornick C. C., Krause-Steinrauf H., Kurtzke J. F., Nazarian S. M., Radford M. J., Rickles F. R., Shabetai R., Deykin D., Panitch H. S., Baker C., Hershey G. L., James M., Shelton B., Asher E., Warfarin in the prevention of stroke associated with nonrheumatic atrial fibrillation. Veterans Affairs Stroke Prevention in Nonrheumatic Atrial Fibrillation Investigators New England Journal of Medicine 1992 327 20 1406 1412
82. Fedak P. W. M., Verma S., David T. E., Leask R. L., Weisel R. D., Butany J., Clinical and pathophysiological implications of a bicuspid aortic valve Circulation 2002 106 8 900 904 (Pubitemid 34925320)
83. Ferencik M., Pape L. A., Changes in size of ascending aorta and aortic valve function with time in patients with congenitally bicuspid aortic valves American Journal of Cardiology 2003 92 1 43 46 (Pubitemid 36782307)
84. Wood P., An appreciation of mitral stenosis. I. Clinical features British Medical Journal 1954 1 4870 1051 1063
85. Rowe J. C., Bland E. F., Sprague H. B., White P. D., The course of mitral stenosis without surgery: ten- and twenty-year perspectives Annals of Internal Medicine 1960 52 741 749
86. Levine H. J., Pauker S. G., Salzman E. W., Antithrombotic therapy in valvular heart disease Chest 1989 95 supplement 2 98S 106S (Pubitemid 19045159)
87. Gohlke-Brwolf C., Acar J., Oakley C., Butchart E., Burckhardt D., Bodnar E., Hall R., Delahaye J. -P., Horstkotte D., Krémer R., Krayenbhl H. P., Krzeminska-Pakula M., Samama M., Guidelines for prevention of thromboembolic events in valvular heart disease. Study Group of the Working Group on Valvular Heart Disease of the European Society of Cardiology European Heart Journal 1995 16 10 1320 1330
88. Salem D. N., Stein P. D., Al-Ahmad A., Bussey H. I., Horstkotte D., Miller N., Pauker S. G., Antithrombotic therapy in valvular heart diseasenative and prosthetic: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy Chest 2004 126 supplement 3 457S 482S (Pubitemid 39297961)
89. Bonow R. O., Carabello B. A., Kanu C., Chatterjee K., De Leon A. C. Jr., Faxon D. P., Freed M. D., Gaasch W. H., Lytle B. W., Nishimura R. A., O'Gara P. T., O'Rourke R. A., Otto C. M., Shah P. M., ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the Management of Patients With Valvular Heart Disease): developed in collaboration with the Society of Cardiovascular Anesthesiologists: endorsed by the Society for Cardiovascular Angiography and Interventions and the Society of Thoracic Surgeons Circulation 2006 114 5 e84 e231
90. Baudet E. M., Puel V., McBride J. T., Grimaud J. P., Roques F., Clerc F., Roques X., Laborde N., Long-term results of valve replacement with the St. Jude Medical prosthesis Journal of Thoracic and Cardiovascular Surgery 1995 109 5 858 870
91. Vongpatanasin W., Hillis L. D., Lange R. A., Prosthetic heart valves New England Journal of Medicine 1996 335 6 407 416 (Pubitemid 26257250)
92. Grunkemeier G. L., Li H. H., Naftel D. C., Starr A., Rahimtoola S. H., Long-term performance of heart valve prostheses Current Problems in Cardiology 2000 25 2 73 154
93. Cannegieter S. C., Rosendaal F. R., Briet E., Thromboembolic and bleeding complications in patients with mechanical heart valve prostheses Circulation 1994 89 2 635 641 (Pubitemid 24056190)
94. Cannegieter S. C., Rosendaal F. R., Wintzen A. R., van der Meer F. J., Vandenbroucke J. P., Briet E., Optimal oral anticoagulant therapy in patients with mechanical heart valves New England Journal of Medicine 1995 333 1 11 17
95. Butchart E. G., Lewis P. A., Bethel J. A., Breckenridge I. M., Adjusting anticoagulation to prosthesis thrombogenicity and patient risk factors. Recommendations for the Medtronic Hall valve Circulation 1991 84 III61 III69
96. Horstkotte D., Schulte H., Bircks W., Strauer B., Unexpected findings concerning thromboembolic complications and anticoagulation after complete 10 year follow up of patients with St. Jude Medical prostheses The Journal of Heart Valve Disease 1993 2 3 291 301
97. Acar J., Iung B., Boissel J. P., Samama M. M., Michel P. L., Teppe J. P., Pony J. C., Breton H. L., Thomas D., Isnard R., De Gevigney G., Viguier E., Sfihi A., Hanania G., Ghannem M., Mirode A., Nemoz C., AREVA: multicenter randomized comparison of low-dose versus standard-dose anticoagulation in patients with mechanical prosthetic heart valves Circulation 1996 94 9 2107 2112 (Pubitemid 26360501)
98. Stein P. D., Alpert J. S., Bussey H. I., Dalen J. E., Turpie A. G., Antithrombotic therapy in patients with mechanical and biological prosthetic heart valves Chest 2001 119 supplement 1 220S 227S (Pubitemid 32154202)
99. Al-Khadra A. S., Salem D. N., Rand W. M., Udelson J. E., Smith J. J., Konstam M. A., Warfarin anticoagulation and survival: a cohort analysis from the Studies of Left Ventricular Dysfunction Journal of the American College of Cardiology 1998 31 4 749 753 (Pubitemid 28186406)
100. Meschengieser S. S., Fondevila C. G., Frontroth J., Santarelli M. T., Lazzari M. A., Low-intensity oral anticoagulation plus low-dose aspirin versus high-intensity oral anticoagulation alone: a randomized trial in patients with mechanical prosthetic heart valves Journal of Thoracic and Cardiovascular Surgery 1997 113 5 910 916 (Pubitemid 27216500)
101. Gilon D., Buonanno F. S., Joffe M. M., Leavitt M., Marshall J. E., Kistler J. P., Levine R. A., Lack of evidence of an association between mitral-valve prolapse and stroke in young patients New England Journal of Medicine 1999 341 1 8 13 (Pubitemid 29293714)
102. Freed L. A., Benjamin E. J., Levy D., Larson M. G., Evans J. C., Fuller D. L., Lehman B., Levine R. A., Mitral valve prolapse in the general population: the benign nature of echocardiographic features in the Framingham Heart Study Journal of the American College of Cardiology 2002 40 7 1298 1304
103. Freed L. A., Levy D., Levine R. A., Larson M. G., Evans J. C., Fuller D. L., Lehman B., Benjamin E. J., Prevalence and clinical outcome of mitral-valve prolapse New England Journal of Medicine 1999 341 1 1 7 (Pubitemid 29293713)
104. Sacco R. L., Adams R., Albers G., Alberts M. J., Benavente O., Furie K., Goldstein L. B., Gorelick P., Halperin J., Harbaugh R., Johnston S. C., Katzan I., Kelly-Hayes M., Kenton E. J., Marks M., Schwamm L. H., Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack. A statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline Stroke 2006 37 2 577 617 (Pubitemid 43732031)
105. Preliminary report of the Stroke Prevention in Atrial Fibrillation Study New England Journal of Medicine 1990 322 12 863 868
106. Rosen S. E., Borer J. S., Hochreiter C., Supino P., Roman M. J., Devereux R. B., Kligfield P., Bucek J., Natural history of the asymptomatic/minimally symptomatic patient with severe mitral regurgitation secondary to mitral valve prolapse and normal right and left ventricular performance American Journal of Cardiology 1994 74 4 374 380 (Pubitemid 24253476)
107. McKhann G. M., Goldsborough M. A., Borowicz L. M. Jr., Mellits E. D., Brookmeyer R., Quaskey S. A., Baumgartner W. A., Cameron D. E., Stuart R. S., Gardner T. J., Predictors of stroke risk in coronary artery bypass patients Annals of Thoracic Surgery 1997 63 2 516 521 (Pubitemid 27084583)
108. Selnes O. A., McKhann G. M., Coronary-artery bypass surgery and the brain New England Journal of Medicine 2001 344 6 451 452 (Pubitemid 32128679)
109. Bucerius J., Gummert J. F., Borger M. A., Walther T., Doll N., Onnasch J. F., Metz S., Falk V., Mohr F. W., Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients Annals of Thoracic Surgery 2003 75 2 472 478 (Pubitemid 36184491)
110. Floyd T. F., Shah P., Price C. C., Harris F., Ratcliffe S. J., Acker M. A., Bavaria J. E., Rahmouni H., Kuersten B., Wiegers S., McGarvey M. L., Woo J. Y., Pochettino A. A., Melhem E. R., Clinically silent cerebral ischemic events after cardiac surgery: their incidence, regional vascular occurrence, and procedural dependence Annals of Thoracic Surgery 2006 81 6 2160 2166 (Pubitemid 43775595)
111. Roach G. W., Kanchuger M., Mangano C. M., Newman M., Nussmeier N., Wolman R., Aggarwal A., Marschall K., Graham S. H., Ley C., Ozanne G., Mangano D. T., Adverse cerebral outcomes after coronary bypass surgery. Multicenter Study of Perioperative Ischemia Research Group and the Ischemia Research and Education Foundation Investigators New England Journal of Medicine 1996 335 25 1857 1863
112. Peel G. K., Stamou S. C., Dullum M. K., Hill P. C., Jablonski K. A., Bafi A. S., Boyce S. W., Petro K. R., Corso P. J., Chronologic distribution of stroke after minimally invasive versus conventional coronary artery bypass Journal of the American College of Cardiology 2004 43 5 752 756 (Pubitemid 38296471)
113. Bucerius J., Gummert J. F., Borger M. A., Walther T., Doll N., Onnasch J. F., Metz S., Falk V., Mohr F. W., Stroke after cardiac surgery: a risk factor analysis of 16,184 consecutive adult patients Annals of Thoracic Surgery 2003 75 2 472 478 (Pubitemid 36184491)
114. Segal A. Z., Abernethy W. B., Palacios I. F., BeLue R., Rordorf G., Stroke as a complication of cardiac catheterization: risk factors and clinical features Neurology 2001 56 7 975 977 (Pubitemid 32290820)
115. Bsing K. A., Schulte-Sasse C., Flchter S., Sselbeck T., Haase K. K., Neff W., Hirsch J. G., Borggrefe M., Dber C., Cerebral infarction: incidence and risk factors after diagnostic and interventional cardiac catheterizationprospective evaluation at diffusion-weighted MR imaging Radiology 2005 235 1 177 183 (Pubitemid 40432252)
116. Oezbek C., Heisel A., Voelk M., Bay W., Berg G., Sen S., Schieffer H., Management of stroke complicating cardiac catheterization with recombinant tissue-type plasminogen activator American Journal of Cardiology 1995 76 10 733 735
117. Malani P. N., Dyke D. B., Pagani F. D., Chenoweth C. E., Nosocomial infections in left ventricular assist device recipients Clinical Infectious Diseases 2002 34 10 1295 1300 (Pubitemid 34507937)
118. Libman R. B., Wirkowski E., Neystat M., Barr W., Gelb S., Graver M., Stroke associated with cardiac surgery. Determinants, timing, and stroke subtypes Archives of Neurology 1997 54 1 83 87 (Pubitemid 27044413)
119. Andersen H. R., Thuesen L., Bagger J. P., Vesterlund T., Thomsen P. E., Prospective randomised trial of atrial versus ventricular pacing in sick-sinus syndrome Lancet 1994 344 8936 1523 1528 (Pubitemid 24357708)
120. Greenspon A. J., Hart R. G., Dawson D., Hellkamp A. S., Silver M., Flaker G. C., Schron E., Goldman L., Lee K. L., Lamas G. A., Predictors of stroke in patients paced for sick sinus syndrome Journal of the American College of Cardiology 2004 43 9 1617 1622 (Pubitemid 38561343)
121. Sgarbossa E. B., Pinski S. L., Maloney J. D., Simmons T. W., Wilkoff B. L., Castle L. W., Trohman R. G., Chronic atrial fibrillation and stroke in paced patients with sick sinus syndrome. Relevance of clinical characteristics and pacing modalities Circulation 1993 88 3 1045 1053 (Pubitemid 23264021)
122. Lechat P., Mas J. L., Lascault G., Loron Ph.., Theard M., Klimczac M., Drobinski G., Thomas D., Grosgogeat Y., Prevalence of patent foramen ovale in patients with stroke New England Journal of Medicine 1988 318 18 1148 1152
123. Di Tullio M., Sacco R. L., Gopal A., Mohr J. P., Homma S., Patent foramen ovale as a risk factor for cryptogenic stroke Annals of Internal Medicine 1992 117 6 461 465
124. Knauth M., Ries S., Pohimann S., Kerby T., Forsting M., Daffertshofer M., Hennerici M., Sartor K., Cohort study of multiple brain lesions in sport divers: role of a patent foramen ovale British Medical Journal 1997 314 7082 701 705 (Pubitemid 27113070)
125. Anzola G. P., Magoni M., Guindani M., Rozzini L., Dalla Volta G., Potential source of cerebral embolism in migraine with aura: a transcranial Doppler study Neurology 1999 52 8 1622 1625 (Pubitemid 29220637)
126. Overell J. R., Bone I., Lees K. R., Interatrial septal abnormalities and stroke: a meta-analysis of case-control studies Neurology 2000 55 8 1172 1179
127. Lamy C., Giannesini C., Zuber M., Arquizan C., Meder J. F., Trystram D., Coste J., Mas J. L., Clinical and imaging findings in cryptogenic stroke patients with and without patent foramen ovale: the PFO-ASA Study. Atrial Septal Aneurysm Stroke 2002 33 3 706 711 (Pubitemid 34203994)
128. Wammes-van der Heijden E. A., Tijssen C. C., Egberts A. C., Right-to-left shunt and migraine: the strength of the relationship Cephalalgia 2006 26 2 208 213
129. Falk R. H., PFO or UFO? The role of a patent foramen ovale in cryptogenic stroke American Heart Journal 1991 121 4, part 1 1264 1266
130. Schwerzmann M., Seiler C., Lipp E., Guzman R., Lvblad K. O., Kraus M., Kucher N., Relation between directly detected patent foramen ovale and ischemic brain lesions in sport divers Annals of Internal Medicine 2001 134 1 21 24 (Pubitemid 32037339)
131. Maalikjy Akkawi N., Agosti C., Anzola G. P., Borroni B., Magoni M., Pezzini A., Rozzini L., Vignolo L. A., Padovani A., Transient global amnesia: a clinical and sonographic study European Neurology 2003 49 2 67 71 (Pubitemid 36206648)
132. Meissner I., Khandheria B. K., Heit J. A., Petty G. W., Sheps S. G., Schwartz G. L., Whisnant J. P., Wiebers D. O., Covalt J. L., Petterson T. M., Christianson T. J. H., Agmon Y., Patent foramen ovale: innocent or guilty? Evidence from a prospective population-based study Journal of the American College of Cardiology 2006 47 2 440 445 (Pubitemid 43063268)
133. Petty G. W., Khandheria B. K., Meissner I., Whisnant J. P., Rocca W. A., Christianson T. J.H., Sicks J. D., O'Fallon W. M., McClelland R. L., Wiebers D. O., Population-based study of the relationship between patent foramen ovale and cerebrovascular ischemic events Mayo Clinic Proceedings 2006 81 5 602 608
134. Mas J. L., Arquizan C., Lamy C., Zuber M., Cabanes L., Derumeaux G., Coste J., Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both New England Journal of Medicine 2001 345 24 1740 1746
135. Lock J. E., Patent foramen ovale is indicted, but the case hasn't gone to trial Circulation 2000 101 8 838 (Pubitemid 30117874)
136. Deeik R. K., Thomas R. M., Sakiyalak P., Botkin S., Blakeman B., Bakhos M., Minimal access closure of patent foramen ovale: is it also recommended for patients with paradoxical emboli? Annals of Thoracic Surgery 2002 74 4 S1326 S1329
137. Serena J., Segura T., Perez-Ayuso M. J., Bassaganyas J., Molins A., Dvalos A., The need to quantify right-to-left shunt in acute ischemic stroke: a case-control study Stroke 1998 29 7 1322 1328 (Pubitemid 28300064)
138. Wu L. A., Malouf J. F., Dearani J. A., Hagler D. J., Reeder G. S., Petty G. W., Khandheria B. K., Patent foramen ovale in cryptogenic stroke: current understanding and management options Archives of Internal Medicine 2004 164 9 950 956 (Pubitemid 38581513)
139. Homma S., Sacco R. L., Di Tullio M. R., Sciacca R. R., Mohr J. P., Effect of medical treatment in stroke patients with patent foramen ovale: patent foramen ovale in Cryptogenic Stroke Study Circulation 2002 105 22 2625 2631 (Pubitemid 34596039)
140. Messe S. R., Schwartz R. S., Perloff J. K., Rose B. D., Treatment of atrial septal abnormalities (PFO, ASD, and ASA) for prevention of recurrent stroke in adults UpToDate 2006 Waltham, Mass, USA UpToDate
141. Serena J., Marti-Fbregas J., Santamarina E., Rodrguez J. J., Perez-Ayuso M. J., Masjuan J., Segura T., Gllego J., Dvalos A., Recurrent stroke and massive right-to-left shunt. Results from the prospective Spanish multicenter (CODICIA) study Stroke 2008 39 12 3131 3136
142. Ustrell X., Serena J., Santamarina E., Massive right-to-left shunt is associated with good prognosis in patient with cryptogenic ischaemic stroke. Preliminary results from the CODICIA spanish multicentre study Cerebrovascular Diseases 2005 19 supplement 2 25
143. Kizer J. R., Devereux R. B., Patent foramen ovale in young adults with unexplained stroke New England Journal of Medicine 2005 353 22 2361 2372 (Pubitemid 41713748)
144. Messé S. R., Silverman I. E., Kizer J. R., Homma S., Zahn C., Gronseth G., Kasner S. E., Practice parameter: recurrent stroke with patent foramen ovale and atrial septal aneurysm: report of the Quality Standards Subcommittee of the American Academy of Neurology Neurology 2004 62 7 1042 1050 (Pubitemid 38456495)
145. Sacco R. L., Adams R., Albers G., Alberts M. J., Benavente O., Furie K., Goldstein L. B., Gorelick P., Halperin J., Harbaugh R., Johnston S. C., Katzan I., Kelly-Hayes M., Kenton E. J., Marks M., Schwamm L. H., Guidelines for prevention of stroke in patients with ischemic stroke or transient ischemic attack: a statement for healthcare professionals from the American Heart Association/American Stroke Association Council on Stroke: co-sponsored by the Council on Cardiovascular Radiology and Intervention: the American Academy of Neurology affirms the value of this guideline Circulation 2006 113 10 e409 e449
146. Cerebral Embolism Task Force, Cardiogenic brain embolism Archives of Neurology 1986 43 1 71 84
147. Cerebral Embolism Task Force, Cardiogenic brain embolism. The second report of the Cerebral Embolism Task Force Archives of Neurology 1989 46 7 727 743
148. Pruitt A. A., Rubin R. H., Karchmer A. W., Duncan G. W., Neurologic complications of bacterial endocarditis Medicine 1978 57 4 329 343 (Pubitemid 8361632)
149. Gransden W. R., Eykyn S. J., Leach R. M., Neurological presentations of native valve endocarditis Quarterly Journal of Medicine 1989 73 272 1135 1142 (Pubitemid 20019607)
150. Salgado A. V., Furlan A. J., Keys T. F., Nichols T. R., Beck G. J., Neurologic complications of endocarditis: a 12-year experience Neurology 1989 39 2 173 178
151. Kanter M. C., Hart R. G., Neurologic complications of infective endocarditis Neurology 1991 41 7 1015 1020
152. Pruitt A. A., Neurologic complications of infective endocarditis. Review of an evolving disease and its management issues in the 1990s Neurologist 1995 1 20 34
153. Heiro M., Nikoskelainen J., Engblom E., Kotilainen E., Marttila R., Kotilainen P., Neurologic manifestations of infective endocarditis: a 17-year experience in a teaching hospital in Finland Archives of Internal Medicine 2000 160 18 2781 2787
154. Mylonakis E., Calderwood S. B., Infective endocarditis in adults New England Journal of Medicine 2001 345 18 1318 1330
155. Stilhart B., Aboulker J., Khouadja F., Robine D., Ouahes O., Redondo A., Should the aneurysms of Osler's disease be investigated and operated on prior to hemorrhage? Neurochirurgie 1986 32 5 410 417
156. Lopez J. A., Ross R. S., Fishbein M. C., Siegel R. J., Nonbacterial thrombotic endocarditis: a review American Heart Journal 1987 113 3 773 784 (Pubitemid 17036729)
157. Futrell N., Millikan C., Frequency, etiology, and prevention of stroke in patients with systemic lupus erythematosus Stroke 1989 20 5 583 591 (Pubitemid 19139084)
158. Fluture A., Chaudhari S., Frishman W. H., Valvular heart disease and systemic lupus erythematosus: therapeutic implications Heart Disease 2003 5 5 349 353 (Pubitemid 37280777)
159. Sandercock P. A., Counsell C., Kamal A. K., Anticoagulants for acute ischaemic stroke Cochrane Database of Systematic Reviews 2008 8 4
160. Paciaroni M., Agnelli G., Micheli S., Caso V., Efficacy and Safety of Anticoagulant Treatment in Acute Cardioembolic Stroke. A Meta-Analysis of Randomized Controlled Trial Stroke 2007 38 2 423 430 (Pubitemid 46184320)
161. Camerlingo M., Salvi P., Belloni G., Gamba T., Cesana B. M., Mamoli A., Intravenous heparin started within the first 3 hours after onset of symptoms as a treatment for acute nonlacunar hemispheric cerebral infarctions Stroke 2005 36 11 2415 2420 (Pubitemid 41566969)
162. Saxena R., Lewis S., Berge E., Sandercock P. A. G., Koudstaal P. J., Risk of early death and recurrent stroke and effect of heparin in 3169 patients with acute ischemic stroke and atrial fibrillation in the International Stroke Trial Stroke 2001 32 10 2333 2337 (Pubitemid 32954805)
163. Cerebral Embolism Study Group, Immediate anticoagulation of embolic stroke: a randomized trial Stroke 1983 14 5 668 676
164. Bath P. M., Lindenstrom E., Boysen G., De Deyn P., Friis P., Leys D., Marttila R., Olsson J. -E., O'Neill D., Orgogozo J. -M., Ringelstein B., Van Der Sande J. -J., Turpie A. G.G., Tinzaparin in acute ischaemic stroke (TAIST): a randomised aspirin-controlled trial Lancet 2001 358 9283 702 710 (Pubitemid 32823398)
165. Berge E., Abdelnoor M., Nakstad P. H., Sandset P. M., Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study. HAEST Study Group Lancet 2000 355 9211 1205 1210 (Pubitemid 30184528)
166. Hommel M., Fraxiparine in Ischemic Stroke Study (FISS bis) Cerebrovascular disease 1998 8 supplement 4 19
167. The Publications Committee for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators, Low molecular weight heparinoid, ORG 10172 (danaparoid), and outcome after acute ischemic stroke: a randomized controlled trial Journal of the American Medical Association 1998 279 16 1265 1272
168. Yu H., Muoz E. M., Edens R. E., Linhardt R. J., Kinetic studies on the interactions of heparin and complement proteins using surface plasmon resonance Biochimica et Biophysica Acta 2005 1726 2 168 176 (Pubitemid 41572256)
169. Pevni D., Frolkis I., Shapira I., Schwartz D., Yuhas Y., Schwartz I. F., Chernichovski T., Uretzky G., Heparin added to cardioplegic solution inhibits tumor necrosis factor-alpha production and attenuates myocardial ischemic-reperfusion injury Chest 2005 128 3 1805 1811 (Pubitemid 41324479)
170. Esmon C. T., Inflammation and thrombosis Journal of Thrombosis and Haemostasis 2003 1 7 1343 1348
171. Vignoli A., Marchetti M., Balducci D., Barbui T., Falanga A., Differential effect of the low-molecular-weight heparin, dalteparin, and unfractionated heparin on microvascular endothelial cell hemostatic properties Haematologica 2006 91 2 207 214
172. Cervera., Justicia C., Reverter J. C., Planas A. M., Chamorro., Steady plasma concentration of unfractionated heparin reduces infarct volume and prevents inflammatory damage after transient focal cerebral ischemia in the rat Journal of Neuroscience Research 2004 77 4 565 572 (Pubitemid 39007008)
173. Hart R. G., Palacio S., Pearce L. A., Atrial fibrillation, stroke, and acute antithrombotic therapy: analysis of randomized clinical trials Stroke 2002 33 11 2722 2727 (Pubitemid 35266448)
174. International Stroke Trial Collaborative Group, The International Stroke Trial (IST): a randomised trial of aspirin, subcutaneous heparin, both, or neither among 19435 patients with acute ischaemic stroke Lancet 1997 349 9065 1569 1581
175. CAST (Chinese Acute Stroke Trial) Collaborative Group, CAST: randomised placebo-controlled trial of early aspirin use in 20,000 patients with acute ischaemic stroke Lancet 1997 349 9066 1641 1649
176. Berge E., Abdelnoor M., Nakstad P. H., Sandset P. M., Low molecular-weight heparin versus aspirin in patients with acute ischaemic stroke and atrial fibrillation: a double-blind randomised study Lancet 2000 355 9211 1205 1210 (Pubitemid 30184528)
177. Saxena R., Lewis S., Berge E., Sandercock P. A. G., Koudstaal P. J., Risk of early death and recurrent stroke and effect of heparin in 3169 patients with acute ischemic stroke and atrial fibrillation in the International Stroke Trial Stroke 2001 32 10 2333 2337 (Pubitemid 32954805)
178. Kay R., Wong K. S., Yu Y. L., Chan Y. W., Tsoi T. H., Ahuja A. T., Chan FU. L., Fong KA. Y., Law C. B., Wong A., Woo J., Low-molecular-weight heparin for the treatment of acute ischemic stroke New England Journal of Medicine 1995 333 24 1588 1593
179. Wong K. S., Chen C., Ng P. W., Tsoi T. H., Li HO. L., Fong W. C., Yeung J., Wong C. K., Yip K. K., Gao H., Wong H. B., Low-molecular-weight heparin compared with aspirin for the treatment of acute ischaemic stroke in Asian patients with large artery occlusive disease: a randomised study Lancet Neurology 2007 6 5 407 413 (Pubitemid 46551851)
180. Diener H. C., Ringelstein E. B., Von Kummer R., Langohr H. D., Bewermeyer H., Landgraf H., Hennerici M., Welzel D., Grve M., Brom J., Weidinger G., Treatment of acute ischemic stroke with the low-molecular-weight heparin certoparin: results of the TOPAS trial. Therapy of Patients With Acute Stroke (TOPAS) Investigators Stroke 2001 32 1 22 29 (Pubitemid 32065699)
181. Bath P. M., Lindenstrom E., Boysen G., De Deyn P., Friis P., Leys D., Marttila R., Olsson J. -E., O'Neill D., Orgogozo J. -M., Ringelstein B., Van Der Sande J. -J., Turpie A. G.G., Tinzaparin in acute ischaemic stroke (TAIST): a randomised aspirin-controlled trial Lancet 2001 358 9283 702 710 (Pubitemid 32823398)
182. The Publications Committee for the Trial of ORG 10172 in Acute Stroke Treatment (TOAST) Investigators, Low molecular weight heparinoid, ORG 10172 (danaparoid), and outcome after acute ischemic stroke: a randomized controlled trial Journal of the American Medical Association 1998 279 16 1265 1272
183. Gubitz G., Sandercock P., Counsell C., Anticoagulants for acute ischaemic stroke Cochrane database of systematic reviews 2004 3
184. Camerlingo M., Salvi P., Belloni G., Gamba T., Cesana B. M., Mamoli A., Intravenous heparin started within the first 3 hours after onset of symptoms as a treatment for acute nonlacunar hemispheric cerebral infarctions Stroke 2005 36 11 2415 2420 (Pubitemid 41566969)
185. Chamorro A., Busse O., Obach V., Toni D., Sandercock P., Reverter J. C., Cervera A., Torres F., Dvalos A.., The rapid anticoagulation prevents ischemic damage study in acute strokefinal results from the writing committee Cerebrovascular Diseases 2005 19 6 402 404 (Pubitemid 40910959)
186. Chamorro A., Immediate anticoagulation for acute stroke in atrial fibrillation: yes Stroke 2006 37 12 3052 3053 (Pubitemid 44900830)
187. Sandercock P., Immediate anticoagulation for acute stroke in atrial fibrillation: no Stroke 2006 37 12 3054 3055 (Pubitemid 44900831)
188. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack Lancet 2001 358 9287 1033 1041
189. O'Donnell H. C., Rosand J., Knudsen K. A., Furie K. L., Segal A. Z., Chiu R. I., Ikeda D., Greenberg S. M., Apolipoprotein E genotype and the risk of recurrent lobar intracerebral hemorrhage New England Journal of Medicine 2000 342 4 240 245 (Pubitemid 30058955)
190. Eckman M. H., Rosand J., Knudsen K. A., Singer D. E., Greenberg S. M., Can patients be anticoagulated after intracerebral hemorrhage? A decision analysis Stroke 2003 34 7 1710 1716 (Pubitemid 36842632)
191. Donaldson J. O., Lee N. S., Yerby M., Devinsky O., Arterial and venous stroke associated with pregnancy Neurologic Clinics. Neurologic Complications of Pregnanc 1994 Philadelphia, Pa, USA W. B. Saunders 583 599 (Pubitemid 24279137)
192. Iturbe-Alessio I., Fonseca M. C., Mutchinik O., Santos M. A., Zajaras A., Salazar E., Risks of anticoagulant therapy in pregnant women with artificial heart valves New England Journal of Medicine 1986 315 22 1390 1393 (Pubitemid 17055412)
193. Sbarouni E., Oakley C. M., Outcome of pregnancy in women with valve prostheses British Heart Journal 1994 71 2 196 201 (Pubitemid 24092707)
194. Hung L., Rahimtoola S. H., Prosthetic heart valves and pregnancy Circulation 2003 107 9 1240 1246 (Pubitemid 36314404)
195. Wong V., Cheng C. H., Chan K. C., Fetal and neonatal outcome of exposure to anticoagulants during pregnancy American Journal of Medical Genetics 1993 45 1 17 21 (Pubitemid 23017978)
196. Hirsh J., Fuster V., Ansell J., Halperin J. L., American Heart Association/American College of Cardiology Foundation guide to warfarin therapy Journal of the American College of Cardiology 2003 41 9 1633 1652 (Pubitemid 36543387)
197. Ginsberg J. S., Hirsh J., Use of antithrombotic agents during pregnancy Chest 1995 108 supplement 4 305S 311S
198. Landefeld C. S., Beyth R. J., Anticoagulant-related bleeding: clinical epidemiology, prediction, and prevention American Journal of Medicine 1993 95 3 315 328 (Pubitemid 23270290)
199. Hirsh J., Kearon C., Ginsberg J., Duration of anticoagulant therapy after first episode of venous thrombosis in patients with inherited thrombophilia Archives of Internal Medicine 1997 157 19 2174 2177 (Pubitemid 27451142)
200. van der Meer F. J., Rosendaal F. R., Vandenbroucke J. P., Briet E., Bleeding complications in oral anticoagulant therapy. An analysis of risk factors Archives of Internal Medicine 1993 153 13 1557 1562 (Pubitemid 23205854)
201. Odén A., Fahlén M., Hart R. G., Optimal INR for prevention of stroke and death in atrial fibrillation: a critical appraisal Thrombosis Research 2006 117 5 493 499 (Pubitemid 43326133)
202. Fihn S. D., McDonell M., Martin D., Henikoff J., Vermes D., Kent D., White R. H., Risk factors for complications of chronic anticoagulation. A multicenter study. Warfarin optimized outpatient follow-up study group Annals of Internal Medicine 1993 118 7 511 520 (Pubitemid 23085793)
203. Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials Archives of Internal Medicine 1994 154 13 1449 1457
204. Steiner T., Rosand J., Diringer M., Intracerebral hemorrhage associated with oral anticoagulant therapy: current practices and unresolved questions Stroke 2006 37 1 256 262 (Pubitemid 43732088)
205. Smith N. L., Psaty B. M., Furberg C. D., White R., Lima J. A. C., Newman A. B., Manolio T. A., Temporal trends in the use of anticoagulants among older adults with atrial fibrillation Archives of Internal Medicine 1999 159 14 1574 1578 (Pubitemid 29340311)
206. Morocutti C., Amabile G., Fattapposta F., Nicolosi A., Matteoli S., Trappolini M., Cataldo G., Milanesi G., Lavezzari M., Pamparana F., Coccheri S., Indobufen versus warfarin in the secondary prevention of major vascular events in nonrheumatic atrial fibrillation. SIFA (Studio Italiano Fibrillazione Atriale) Investigators Stroke 1997 28 5 1015 1021 (Pubitemid 27209152)
207. Bousser M. G., Bouthier J., Buller H. R., Comparison of idraparinux with vitamin K antagonists for prevention of thromboembolism in patients with atrial fibrillation: a randomised, open-label, non-inferiority trial Lancet 2008 371 9609 315 321
208. Kakar P., Watson T., Lip G. Y., Drug evaluation: rivaroxaban, an oral, direct inhibitor of activated factor X Current Opinion in Investigational Drugs 2007 8 3 256 265 (Pubitemid 46438462)
209. Ndegwa S., Moulton K., Argez C., Dabigatran or Rivaroxaban Versus Other Anticoagulants for Thromboprophylaxis after Major Orthopedic Surgery: Systematic Review of Comparative Clinical-Effectiveness and Safety 2009 Ottawa, Canada Canadian Agency for Drugs and Technologies in Health
210. Eriksson B. I., Quinlan D. J., Weitz J. I., Comparative pharmacodynamics and pharmacokinetics of oral direct thrombin and factor Xa inhibitors in development Clinical Pharmacokinetics 2009 48 1 1 22
211. Weitz J. I., Bates S. M., New anticoagulants Journal of Thrombosis and Haemostasis 2005 3 8 1843 1853 (Pubitemid 41716571)
212. Heparin: unfractionated [CPhA monograph] eCPS [database online] 2005 Ottawa, Canada Canadian Pharmacists Association
213. Aldocumar (warfarin sodium): product monograph. Vademcum: Aldo-Union, Spain, 2010
214. Pradaxa (dabigatran etexilate): product monograph. Vademcum: Boehringer, Ingelheim Spain, 2010
215. Xarelto (rivaroxaban): product monograph. Vademcum: Bayer, Spain, 2010
216. Clexane (enoxaparin sodium): product monograph. Vademcum: Sanofi-aventis, Spain, 2010
217. Fragmin (dalteparin sodium): product monograph. Vademcum: Pfizer, Spain, 2010
218. Garcia D., Libby E., Crowther M. A., The new oral anticoagulants Blood 2010 115 1 15 20
219. Hankey G. J., Eikelboom J. W., Antithrombotic drugs for patients with ischaemic stroke and transient ischaemic attack to prevent recurrent major vascular events The Lancet Neurology 2010 9 3 273 284
220. Olsson S. B., Stroke prevention with the oral direct thrombin inhibitor ximelagatran compared with warfarin in patients with non-valvular atrial fibrillation (SPORTIF III): randomised controlled trial Lancet 2003 362 9397 1691 1698 (Pubitemid 37468318)
221. Albers G. W., Diener H. C., Frison L., Ximelagatran vs warfarin for stroke prevention in patients with nonvalvular atrial fibrillation: a randomized trial Journal of the American Medical Association 2005 293 6 690 698
222. O'Brien C. L., Gage B. F., Costs and effectiveness of ximelagatran for stroke prophylaxis in chronic atrial fibrillation Journal of the American Medical Association 2005 293 6 699 706 (Pubitemid 40216039)
223. Gurewich V., Ximelagatranpromises and concerns Journal of the American Medical Association 2005 293 6 736 739
224. Connolly S. J., Ezekowitz M. D., Yusuf S., Eikelboom J., Oldgren J., Parekh A., Pogue J., Reilly P. A., Themeles E., Varrone J., Wang S., Alings M., Xavier D., Zhu J., Diaz R., Lewis B. S., Darius H., Diener H. C., Joyner C. D., Wallentin L., Alings A. M. W., Amerena J. V., Avezum A., Baumgartner I., Brugada J., Budaj A., Caicedo V., Ceremuzynski L., Chen J. H., Commerford P. J., Connolly S. J., Dans A. L., Darius H., Di Pasquale G., Diaz R., Erol C., Ezekowitz M. D., Ferreira J., Flaker G. C., Flather M. D., Franzosi M. G., Gamboa R., Golitsyn S. P., Gonzalez Hermosillo J. A., Halon D., Heidbuchel H., Hohnloser S. H., Hori M., Huber K., Jansky P., Kamensky G., Keltai M., Kim S., Lau C. P., Le Heuzey J. Y. F., Lewis B. S., Liu L. S., Nanas J., Oldgren J., Pais P. S., Parkhomenko A. N., Pedersen K. E., Piegas L. S., Raev D., Razali O., Simmers T. A., Smith P. J., Talajic M., Tan R. S., Tanomsup S., Toivonen L., Vinereanu D., Wallentin L., Xavier D., Yusuf S., Zhu J., Dabigatran versus warfarin in patients with atrial fibrillation New England Journal of Medicine 2009 361 12 1139 1151
225. Gage B. F., Can we rely on RE-LY? New England Journal of Medicine 2009 361 12 1200 1202
226. Clot drug 'cold save thousands' 2008. BBC News Online (BBC) http://news.bbc.co.uk/2/hi/health/7354818.stm
227. ROCKET AF Study Investigators, Rivaroxaban-once daily, oral, direct factor Xa inhibition compared with vitamin K antagonism for prevention of stroke and Embolism Trial in Atrial Fibrillation: rationale and design of the ROCKET AF study American Heart Journal 2010 159 3, article e1 340 347
228. Cox J. L., Boineau J. P., Schuessler R. B., Jaquiss R. D. B., Lappas D. G., Modification of the Maze procedure for atrial flutter and atrial fibrillation. I. Rationale and surgical results Journal of Thoracic and Cardiovascular Surgery 1995 110 2 473 484
229. Ostermayer S. H., Reisman M., Kramer P. H., Matthews R. V., Gray W. A., Block P. C., Omran H., Bartorelli A. L., Della Bella P., Di Mario C., Pappone C., Casale P. N., Moses J. W., Poppas A., Williams D. O., Meier B., Skanes A., Teirstein P. S., Lesh M. D., Nakai T., Bayard Y., Billinger K., Trepels T., Krumsdorf U., Sievert H., Percutaneous left atrial appendage transcatheter occlusion (PLAATO system) to prevent stroke in high-risk patients with non-rheumatic atrial fibrillation: results from the international multi-center feasibility trials Journal of the American College of Cardiology 2005 46 1 9 14 (Pubitemid 40905122)