Management of cancer therapy-induced oral mucositis

Dermatologic Therapy

Volumn 24, Issue 4, 2011, Pages 424-431

  Barasch, Andrei ^a   Epstein, Joel B ^b  

^a WINTHROP UNIVERSITY HOSPITAL   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

cancer; mucositis; prevention; therapy

Indexed keywords

ANTIFUNGAL AGENT; ANTINEOPLASTIC AGENT; ANTIVIRUS AGENT; BENZYDAMINE; BETAMETHASONE; CYCLOPHOSPHAMIDE; CYTOTOXIC AGENT; DEXAMETHASONE; DOCETAXEL; DOXORUBICIN; ETOPOSIDE; FLUOROURACIL; FOLINIC ACID; GEMCITABINE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IFOSFAMIDE; IRINOTECAN; METHOTREXATE; NAVELBINE; OXALIPLATIN; PACLITAXEL; PALIFERMIN; PLATINUM; PREDNISONE; REPIFERMIN; TAXANE DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA3; UNINDEXED DRUG; VINCRISTINE;

BREAST CANCER; CANCER COMBINATION CHEMOTHERAPY; CANCER PALLIATIVE THERAPY; CANCER PATIENT; CANCER RADIOTHERAPY; CHEMOPROPHYLAXIS; COLON CANCER; CRYOTHERAPY; CYTOKINE PRODUCTION; DENTAL CARE; DRUG EFFECT; DRUG MEGADOSE; DRUG SAFETY; GOOD CLINICAL PRACTICE; HEAD AND NECK CANCER; HERPES SIMPLEX; HUMAN; LOW DRUG DOSE; LOW LEVEL LASER THERAPY; LUNG CANCER; MUCOSA INFLAMMATION; NEUTROPENIA; NONHODGKIN LYMPHOMA; NONHUMAN; PATHOPHYSIOLOGY; RADIATION INJURY; REVIEW; STOMATITIS; THRUSH; ULCERATIVE ORAL MUCOSITIS;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; HUMANS; NEOPLASMS; QUALITY OF LIFE; RADIATION INJURIES; STOMATITIS;

EID: 80052766458     PISSN: 13960296     EISSN: 15298019     Source Type: Journal    
DOI: 10.1111/j.1529-8019.2011.01434.x     Document Type: Review

References (53)

1. Ferretti GA, Ash RC, Brown AT, et al,. Chlorhexidine for prophylaxis of infections and associated complications in bone marrow transplant patients. J Am Dent Assoc 1987: 114: 461-467.
2. Okuno SH, Foote RL, Loprinzi CL, et al,. A randomized trial of a nonabsorbable antibiotic lozenge given to alleviate radiation-induced mucositis. Cancer 1997: 79: 2193-2199. (Pubitemid 27227385)
3. Raber-Durlacher JE,. Current practices for management of oral mucositis in cancer patients. Support Care Cancer 1999: 7: 71-74. (Pubitemid 29140738)
4. Weisdorf DJ, Bostrom B, Rather D, et al,. Oropharyngeal mucositis complicating bone marrow transplantation: prognostic factors and the effect of chlorhexidine mouth rinse. Bone Marrow Transplant 1989: 4: 89-95. (Pubitemid 19064912)
5. Bellm LA, Epstein JB, Rose-Ped A, Martin P, Fuchs HJ,. Patient reports of complications of bone marrow transplantation. Support Care Cancer 2000: 8: 33-39. (Pubitemid 30096543)
6. Cella D, Pulliam J, Fuchs H, et al,. Evaluation of pain associated with oral mucositis during the acute period after administration of high-dose chemotherapy. Cancer 2003: 98: 406-412. (Pubitemid 36828468)
7. Sonis ST, Elting LS, Keefe D, et al,. Perspectives on cancer therapy-induced mucosal injury. Cancer 2004: 100 (9 Suppl.): 1995-2025.
8. Sonis ST,. The pathobiology of mucositis. Nat Rev Cancer 2004: 4: 277-284. (Pubitemid 38525283)
9. Barasch A, Peterson DE,. Risk factors for ulcerative oral mucositis in cancer patients: unanswered questions. Oral Oncol 2002: 39: 91-100.
10. Chi KW, Chen CH, Chan WK, et al,. Effect of granulocyte-macrophage colony stimulating factor on oral mucositis in head and neck cancer patients after cisplatin, fluorouracil and leukovorin chemotherapy. J Clin Oncol 1995: 13: 2620-2628.
11. Chiara S, Nobile NT, Sanguineti O, Cognein P, Rosso R,. Oral mucositis in advanced colorectal cancer patients receiving continuous 5-fluorouracil (5-FU) infusions (c.i.) + oral leukovorin (L-LV). Support Care Cancer 1996: 4: 238 [abstract].
12. Peterson DE,. Toxicity of chemotherapeutic agents. Semin Oncol 1992: 19: 478-491.
13. Raber-Durlacher JE, Weijl NI, Abu Saris M, et al,. Oral mucositis in patients treated with chemotherapy for solid tumors: analysis of 150 cases. Support Care Cancer 2000: 8: 366-371. (Pubitemid 30650520)
14. Jones JA, Avritscher EBC, Cooksley CD, Michelet M, Bekele BN, Elting LS,. Epidemiology of treatment-associated mucosal injury after treatment with newer regimens for lymphoma, breast, lung, or colorectal cancer. Support Care Cancer 2006: 14 (6): 505-515.
15. Barasch A, Peterson DE, Tanzer JM, et al,. Helium-neon laser effects on conditioning-induced oral mucositis in bone marrow transplantation patients. Cancer 1995: 76: 2550-2556.
16. Woo SB, Sonis ST, Monopoli MM, Sonis AL,. A longitudinal study of oral ulcerative mucositis in bone marrow transplant recipients. Cancer 1993: 72: 1612-1617. (Pubitemid 23249287)
17. Adamietz IA, Rahn R, Bottcher HD, et al,. Prophylaxis with providone-iodine against induction of oral mucositis by radiochemotherapy. Support Care Cancer 1998: 6: 373-377. (Pubitemid 28337128)
18. Ãhrn KE, Wahlin YB, Sjoden PO,. Oral status during radiotherapy and chemotherapy: a descriptive study of patients experiences and the occurrence of oral complications. Support Care Cancer 2001: 9: 247-257.
19. Feld R,. The role of surveillance culture in patients likely to develop chemotherapy-induced mucositis. Support Care Cancer 1997: 5: 371-375. (Pubitemid 27402589)
20. Bondi E, Baroni C, Prete A, et al,. Local antimicrobial therapy of oral mucositis in paediatric patients undergoing bone marrow transplantation. Oral Oncol 1997: 33: 322-326. (Pubitemid 28129232)
21. Epstein JB, Ransier A, Sherlock CH, Spinelli JJ, Reece D,. Acyclovir prophylaxis of oral herpes virus during bone marrow transplantation. Eur J Cancer B Oral Oncol 1996: 32B: 158-162.
22. Donnelly JP, Bellm LA, Epstein JB, Sonis ST, Symonds RP,. Antimicrobial therapy to prevent or treat oral mucositis. Lancet Infect Dis 2003: 3: 405-412. (Pubitemid 36791117)
23. Abdelaal AS, Barker DS, Fergusson MM,. Treatment for radiation-induced mucositis. Lancet 1989: 1: 97.
24. Leborgne JH, Leborgne F, Zubizarreta E, Ortega B, Mezzera J,. Corticosteroids and radiation mucositis in head and neck cancer. A double-blind placebo-controlled randomized trial. Radiother Oncol 1998: 47: 145-148. (Pubitemid 28275923)
25. Epstein JB, Silverman S Jr, Paggiarino DA, et al,. Benzydamine HCl for prophylaxis of radiation-induced oral mucositis: results from a multicenter, randomized, double-blind, placebo-controlled clinical trial. Cancer 2001: 92: 875-885. (Pubitemid 32783076)
26. Prada A, Chiesa F,. Effects of benzydamine on the oral mucositis during antineoplastic radiotherapy and/or intraarterial chemotherapy. Int J Tissue React 1987: 9: 115-119. (Pubitemid 17097101)
27. Kim JH, Chu FC, Lakshmi V, Houde R,. Benzydamine HCl, a new agent for the treatment of radiation mucositis of the oropharynx. Am J Clin Oncol 1986: 9: 132-134. (Pubitemid 16115725)
28. Samaranayake LP, Robertson AG, McFarlane TW, et al,. The effect of chlorhexidine and benzydamine mouthwashes on mucositis induced by therapeutic irradiation. Clin Radiol 1988: 39: 291-294.
29. Lever SA, Dupuis LL, Chan SL,. Comparative evaluation of benzydamine oral rinse in children with antineoplastic-induced stomatitis. Drug Intell Clin Pharm 1987: 21: 359-361. (Pubitemid 17060495)
30. Schubert MM, Newton RE,. The use of benzydamine HCl for the management of cancer therapy-induced mucositis: preliminary report of a multicenter study. Int J Tissue React 1987: 9: 99-103. (Pubitemid 17097099)
31. Patte C, Laplanche A, Bertozzi AI, et al,. Granulocyte colony-stimulating factor in induction treatment of children with non-Hodgkin's lymphoma: a randomized study of the French Society of Pediatric Oncology. J Clin Oncol 2002: 20 (2): 441-448. (Pubitemid 34072527)
32. Gordon B, Spadinger A, Hodges E, et al,. Effect of granulocyte-macrophage colony stimulating factor on oral mucositis after hematopoietic stem cell transplantation. J Clin Oncol 1994: 12: 1917-1922. (Pubitemid 24349395)
33. Karthaus M, Rosenthal C, Huebner G,. Effect of topical granulocyte colony stimulating factor on oral mucositis: a randomized, placebo-controlled trial. Bone Marrow Transplant 1998: 22: 781-785. (Pubitemid 28488322)
34. Mascarin M, Franchin G, Minatel E, et al,. The effect of granulocyte colony-stimulating factor on oral mucositis in head and neck cancer patients treated with hyperfractionated radiotherapy. Oral Oncol 1999: 35: 203-208. (Pubitemid 29113065)
35. Sonis ST, Costa JW, Evitts SM, Lindquist LE, Nicolson M,. Effect of epidermal growth factor on ulcerative mucositis in hamsters that receive cancer chemotherapy. Oral Surg Oral Med Oral Pathol 1992: 74: 749-755. (Pubitemid 23005444)
36. Sonis ST, van Vught AG, Brien JPO, et al,. Transforming growth factor beta 3-mediated modulation of cell cyclingand attenuation of 5-fluorouracil-induced oral mucositis. Oral Oncol 1997: 33: 47-54.
37. Foncuberta MC, Cagnoni PJ, Brandts CH, et al,. Topical transforming growth factor-beta 3 in the prevention or alleviation of chemotherapy-induced oral mucositis in patients with lymphomas or solid tumors. J Immunother 2001: 24: 384-388. (Pubitemid 32825870)
38. Clarkson JE, Worthington HV, Furness S, et al,. Interventions for treating oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev 2010: 8: CD001973.
39. Danno K, Mori N, Toda K, Kobayashi T, Utani A,. Near-infrared irradiation stimulates cutaneous wound repair: laboratory experiments on possible mechanisms. Photodermatol Photoimmunol Photomed 2001: 17: 261-265. (Pubitemid 33072126)
40. Karu TI,. Photobiology of low power laser effects. Health Phys 1989: 56: 691-704.
41. Migliorati CA, Oberle-Edwards L, Schubert M,. The role of alternative and natural agents, cryotherapy, and/or laser for the management of alimentary mucositis. Support Care Cancer 2006: 14: 533-540.
42. Aisa Y, Mori T, Kudo M, et al,. Oral cryotherapy for the prevention of high-dose melphalan-induced stomatitis in allogeneic hematopoietic stem cell transplant recipients. Support Care Cancer 2005: 13: 266-269. (Pubitemid 40576514)
43. Tartarone A, Matera R, Romano G, Vigliotti ML, Di Renzo N,. Prevention of high-dose melphalan-induced mucositis by cryotherapy. Leuk Lymphoma 2005: 46: 633-634. (Pubitemid 40584886)
44. Spielberger R, Stiff P, Bensinger W, et al,. Palifermin for oral mucositis after intensive therapy for hematologic cancers. N Engl J Med 2004: 351: 2590-2598. (Pubitemid 39628580)
45. Vadhan-Raj S, Trent J, Patel S, et al,. Single-dose palifermin prevents severe oral mucositis during multicycle chemotherapy in patients with cancer: a randomized trial. Ann Intern Med 2010: 153: 358-367.
46. Freytes CO, Ratanatharathorn V, Taylor C, et al,. Phase I/II randomized trial evaluating the safety and clinical effects of repifermin administered to reduce mucositis in patients undergoing hematopoietic stem cell transplantation. Clin Cancer Res 2004: 10: 8318-8324. (Pubitemid 40053392)
47. Epstein JB, Elad S, Eliav E, Jurevic R, Benoliel R,. Orofacial pain in cancer: part II: clinical perspectives and management. J Dent Res 2007: 86: 506-518.
48. Epstein JB, Hong C, Logan RM, et al,. A systematic review of orofacial pain in patients receiving cancer therapy. Support Care Cancer 2010: 18: 1023-1031.
49. Epstein JB, Epstein JD, Epstein MS, Oien H, Truelove EL,. Doxepin rinse for management of mucositis pain in patients with cancer: one week follow-up of topical therapy. Spec Care Dentist 2008: 28: 73-77.
50. Epstein JB, Wilkie DJ, Fischer DJ, Kim Y-O,. Neuropathic and nociceptive pain in head and neck cancer patients receiving radiation therapy. Head Neck Oncol 2009: 1: 26-38.
51. Elting LS, Keefe DM, Sonis ST, et al,. Patient-reported measurements of oral mucositis in head and neck cancer patients treated with radiotherapy with or without chemotherapy: demonstration of increased frequency, severity, resistance to palliation, and impact on quality of life. Cancer 2008: 113: 2704-2713.
52. Keefe DM,. Mucositis guidelines: what have they achieved, and where to from here? Support Care Cancer 2006: 14 (6): 489-491.
53. Rubenstein EB, Peterson DE, Schubert M, et al,. Clinical practice guidelines for the prevention and treatment of cancer therapy-induced oral and gastrointestinal mucositis. Cancer 2004: 100 (9 Suppl.): 2026-2046. (Pubitemid 38525884)