The effect of starch paste and sodium starch glycolate on the compaction behavior of wet granulated acetaminophen formulations

Journal of Excipients and Food Chemicals

Volumn 2, Issue 3, 2011, Pages 64-72

  Patel, Sarsvatkumar ^a,b   Kaushal, Aditya Mohan ^a,c   Bansal, Arvind Kumar Bansal ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b UNIVERSITY OF MINNESOTA   (United States)

^c Bend Research Incorporated   (United States)

Author keywords

Acetaminophen; Binder; Compaction; Disintegrant; Sodium starch glycolate; Starch; Tableting

Indexed keywords

MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE; PARACETAMOL; STARCH; STARCH GLYCOLATE SODIUM;

ANALYTICAL PARAMETERS; ARTICLE; CHEMICAL BINDING; CHEMICAL COMPOSITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG GRANULATION; DRUG GRANULE; ELASTIC ENERGY; MECHANICS; MOISTURE; PUNCH FORCE DISPLACEMENT; TABLET COMPRESSION; TABLET FORMULATION; TABLET MACHINE; TENSILE STRENGTH; THERMODYNAMICS; WET GRANULATION;

EID: 80052728556     PISSN: None     EISSN: 21502668     Source Type: Journal    
DOI: None     Document Type: Article

References (38)

1. Jaffe J., Foss N.E., Compression of crystalline substances, J. Amer. Pharm. Ass. Sci. Ed., (1959), 48, 26-29
2. Train D., An investigation into the compaction of powders, J. Pharm. Pharmacol., (1956), 8, 745-761
3. Ruegger C.E., Celik M., The effect of compression and decompression speed on the mechanical strength of compacts, Pharm. Dev. Technol., (2000), 5, 485-94
4. Edge S., Steele D.F., Staniforth J.N., Chen A., Woodcock P.M., Powder compaction properties of sodium starch glycolate disintegrants, Drug. Dev. Ind. Pharm., (2002), 28, 989-99
5. Hauschild K., Picker-Freyer K.M., Evaluation of a new coprocessed compound based on lactose and maize starch for tablet formulation, AAPS PharmSci., (2004), 6, e16
6. Kachrimanis K., Malamataris S., Compact size and mechanical strength of pharmaceutical diluents, Eur. J. Pharm. Sci., (2005), 24, 169-77
7. Nystrom C., Alderborn G., Duberg M., Bonding surface area and bonding mechanism - two important factors for the understanding of powder compactability, Drug. Dev. Ind. Pharm., (1993), 19, 2143-2196
8. DeCrosta M.T., Schwartz J.B., Wigent R.J., Thermodynemic analysis of compact formation, compaction, unloading and ejection II Mechanical energy (work) and thermal energy (heat) determination of compact unloading and ejection, Int. J. Pharm., (2001), 213, 45-62
9. Ebba F., Piccerelle P., Prinderre P., Opota, D., Joachim, J., Stress relaxation studies of granules as a function of different lubricants, Eur. J. Pharm. Biopharm., (2001), 52, 211-20
10. Garekani H.A., Ford J.L., Rubinstein M.H., Rajabi-Siahboomi A.R., Effect of compression force, compression speed, and particle size on the compression properties of paracetamol, Drug. Dev. Ind. Pharm., (2001), 27, 935-42
11. Yu H.C., Rubinstein M.H., Jackson I.M., Elsabbagh H.M., Multiple compression and plasto-elastic behaviour of paracetamol and microcrystalline cellulose mixtures, J. Pharm. Pharmacol., (1988), 40, 669-73
12. Patel S., Kaushal A.M., Bansal A.K., Effect of particle size and compression force on compaction behavior and derived mathematical parameters of compressibility, Pharm. Res., (2007), 24, 111-24
13. Bolhuis G.K., Film formation by magnesium stearate during mixing and its effect on tableting, Pharm Weekbl., (1975) 110, 317-325
14. Dansereau R., Peck G.E., Effect of variability in the physical and chemical properties of magnesium stearate on the properties of compressed tablets, Drug. Dev. Ind. Pharm., (1987), 13, 975-999
15. Rao K.P., Chawla G., Kaushal A.M., Bansal A.K., Impact of solid-state properties on lubrication efficacy of magnesium stearate, Pharm. Dev. Technol., (2005), 10, 423-437
16. Sun C., Himmelspach M.W., Reduced tabletability of roller compacted granules as a result of granule size enlargement, J. Pharm. Sci., (2006), 95, 200-6
17. Tye C.K., Sun C.C., Amidon, G.E., Evaluation of the effects of tableting speed on the relationships between compaction pressure, tablet tensile strength, and tablet solid fraction, J. Pharm. Sci., (2005), 94, 465-72
18. Kawashima Y., Imai M., Takeuchi H., Yamamoto H., Kamiya K., Hino, T., Improved flowability and compactibility of spherically agglomerated crystals of ascorbic acid for direct tabletting designed by spherical crystallization process, Powder Technol., (2003), 130, 283-289
19. Nokhodchi A., Ford J.L., Rowe P.H., Rubinstein M.H., The influence of moisture content on the consolidation properties of hydroxy propylmethylcellulose K4M (HPMC 2208), J. Pharm. Pharmacol., (1996), 48, 1116-21
20. Schmidt P.C., Herzog R., Calcium phosphates in pharmaceutical tableting. 2. Comparison of tableting properties, Pharm. World Sci., (1993), 15, 116-22
21. Chen Y., Li Y., A new model for predicting moisture uptake by packaged solid pharmaceuticals, Int. J. Pharm., (2003), 255, 217-25
22. Ilkka J., Paronen P., Prediction of the compression behavior of powder mixtures by the Heckel equation, Int. J. Pharm., (1993), 94, 181-187
23. Akande O.F., Rubinstein M.H., Ford J.L., Examination of the compaction properties of a 1:1 acetaminophen:microcrystalline cellulose mixture using precompression and main compression, J. Pharm. Sci., (1997), 86, 900-7
24. Bangudu A.B., Pilpel, N., Tensile strengths of paracetamol and Avicel powders and their mixtures, J. Pharm. Pharmacol., (1984), 36, 717-22
25. Beyer T., Day G.M., Price S.L., The prediction, morphology, and mechanical properties of the polymorphs of paracetamol, J. Am. Chem. Soc., (2001), 123, 5086-94
26. Du J., Hoag S.W., Characterization of excipient and tableting factors that influence folic acid dissolution, friability, and breaking strength of oil- and water-soluble multivitamin with minerals tablets, Drug Dev. Ind. Pharm., (2003), 29, 1137-47
27. Du Ross J.W., Modification of the crystalline structure of sorbitol and its effects on tableting characteristics, Pharm. Technol., (1974), 8, 42.
28. Hiestand E.N., Rationale for and measurement of tableting indices, in Pharmaceutical Powder Compaction Technology, Alderborn G., Nyström C., (eds), Marcel Dekker: New York, 1996, 219-244.
29. Ishino R., Yoshino H., Hirakawa Y., Noda K., Influence of tableting speed on compactibility and compressibility of two direct compressible powders under high speed compression, Chem. Pharm. Bull., (1990), 38, 1987-92
30. Jonat S., Hasenzahl S., Gray A., Schmidt P.C., Influence of compacted hydrophobic and hydrophilic colloidal silicon dioxide on tableting properties of pharmaceutical excipients, Drug Dev. Ind. Pharm., (2005), 31, 687-96
31. Faure A., York P., Rowe R.C., Process control and scale-up of pharmaceutical wet granulation processes: a review, Eur. J. Pharm. Biopharm., (2001), 52, 269-77
32. Matz C., Bauer-Brandl A., Rigassi T., Schubert R., Becker D., On the accuracy of a new displacement instrumentation for rotary tablet presses, Drug Dev. Ind. Pharm., (1999), 25, 117-130
33. Fell J.T., Newton J.M., Effect of particle size and speed of compaction on density changes in tablets of crystalline and spray-dried lactose, J. Pharm. Sci., (1971), 60, 1866-1869
34. Fell J.T., Newton J.M., Determination of tablet strength by the diametral compression test, J. Pharm. Sci., (1970), 59, 688-691
35. Akande O.F., Ford J.L., Rowe P.H., Rubinstein M.H., The effects of lag-time and dwell-time on the compaction properties of 1:1 paracetamol/microcrystalline cellulose tablets prepared by pre-compression and main compression, J. Pharm. Pharmacol., (1998), 50, 19-28
36. Bangudu A.B., Pilpel N., Effects of interacting variables on the tensile strengths and disintegration times of paracetamol tablets, J. Pharm. Pharmacol., (1985), 37, 903-5
37. Esezobo S., The effect of some excipients on the physical properties of a paracetamol tablet formulation, J. Pharm. Pharmacol., (1985), 37, 193-5
38. Boutell S., Newton J.M., Bloor J.R., Hayes G., The influence of liquid binder on the liquid mobility and preparation of spherical granules by the process of extrusion/spheronization, Int. J. Pharm, (2002), 238, 61-76