-
1
-
-
15644374841
-
A novel class of orally active non-peptide bradykinin B2 antagonists
-
Abe Y, Kayakiri H, Satoh S, Inoue T, Sawada Y, Inamura N, et al. A novel class of orally active non-peptide bradykinin B2 antagonists. J Med Chem 1998, 41:4053-4061.
-
(1998)
J Med Chem
, vol.41
, pp. 4053-4061
-
-
Abe, Y.1
Kayakiri, H.2
Satoh, S.3
Inoue, T.4
Sawada, Y.5
Inamura, N.6
-
2
-
-
0028220806
-
Reduction by HOE-140, the B-2 kinin receptor antagonist, of antigen-induced nasal blockage
-
Austin CE, Foreman JC, Scadding GK Reduction by HOE-140, the B-2 kinin receptor antagonist, of antigen-induced nasal blockage. Br J Pharmacol 1994, 111:969-971.
-
(1994)
Br J Pharmacol
, vol.111
, pp. 969-971
-
-
Austin, C.E.1
Foreman, J.C.2
Scadding, G.K.3
-
3
-
-
0034986751
-
Kinin-regulated growth of androgen-insensitive prostate cancer PC3 cells requires direct interaction between bradykinin 1 and bradykinin 2 receptors
-
Barki-Harrington L, Daaka Y Kinin-regulated growth of androgen-insensitive prostate cancer PC3 cells requires direct interaction between bradykinin 1 and bradykinin 2 receptors. J Urol 2001, 165:2121-2125.
-
(2001)
J Urol
, vol.165
, pp. 2121-2125
-
-
Barki-Harrington, L.1
Daaka, Y.2
-
4
-
-
0026556434
-
Bioregulation of kinins: kallikreins, kininogens, and kininases
-
Bhoola KD, Figueroa CD, Worthy K Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol Rev 1992, 44:1-80.
-
(1992)
Pharmacol Rev
, vol.44
, pp. 1-80
-
-
Bhoola, K.D.1
Figueroa, C.D.2
Worthy, K.3
-
5
-
-
0026532009
-
Neuropeptide signal transduction in lung cancer: clinical implications of bradykinin sensitivity and overall heterogeneity
-
Bunn PA, Chan DC, Dienhart DG, Tolly R, Togawa M, Jewett PB Neuropeptide signal transduction in lung cancer: clinical implications of bradykinin sensitivity and overall heterogeneity. Cancer Res 1991, 52:24-31.
-
(1991)
Cancer Res
, vol.52
, pp. 24-31
-
-
Bunn, P.A.1
Chan, D.C.2
Dienhart, D.G.3
Tolly, R.4
Togawa, M.5
Jewett, P.B.6
-
6
-
-
18344388451
-
Bradykinin antagonist dimer CU-201 inhibits the growth of human lung cancer cells by a novel "biased agonist" mechanism
-
Chan D, Gera L, Stewart J, Helfrich B, Verella-Garcia M, Johnson G, et al. Bradykinin antagonist dimer CU-201 inhibits the growth of human lung cancer cells by a novel "biased agonist" mechanism. Proc Natl Acad Sci USA 2002, 99:4608-4613.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 4608-4613
-
-
Chan, D.1
Gera, L.2
Stewart, J.3
Helfrich, B.4
Verella-Garcia, M.5
Johnson, G.6
-
7
-
-
0036097190
-
Bradykinin antagonist dimer CU-201 inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents
-
Chan D, Gera L, Stewart J, Helfrich B, Zhao TL, Feng WY, et al. Bradykinin antagonist dimer CU-201 inhibits the growth of human lung cancer cell lines in vitro and in vivo and produces synergistic growth inhibition in combination with other antitumor agents. Clin Cancer Res 2002, 8:1280-1287.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1280-1287
-
-
Chan, D.1
Gera, L.2
Stewart, J.3
Helfrich, B.4
Zhao, T.L.5
Feng, W.Y.6
-
8
-
-
0034624707
-
1-(2-nitrophenyl) thiosemicarbazides: a novel class of potent, orally active non-peptide antagonist for the bradykinin B2 receptor
-
Dziadulewicz EK, Ritchie TJ, Hallett A, Snell CR, Ko SY, Wrigglesworth R, et al. 1-(2-nitrophenyl) thiosemicarbazides: a novel class of potent, orally active non-peptide antagonist for the bradykinin B2 receptor. J Med Chem 2000, 43:769-771.
-
(2000)
J Med Chem
, vol.43
, pp. 769-771
-
-
Dziadulewicz, E.K.1
Ritchie, T.J.2
Hallett, A.3
Snell, C.R.4
Ko, S.Y.5
Wrigglesworth, R.6
-
9
-
-
0033709630
-
Non-competitive pharmacological antagonism at the rabbit B1 receptor
-
Larrivee JF, Gera L, Houle S, Bouthillier J, Bachvarov DR, Stewart JM, et al. Non-competitive pharmacological antagonism at the rabbit B1 receptor. Brit J Pharmacol 2000, 131:885-892.
-
(2000)
Brit J Pharmacol
, vol.131
, pp. 885-892
-
-
Larrivee, J.F.1
Gera, L.2
Houle, S.3
Bouthillier, J.4
Bachvarov, D.R.5
Stewart, J.M.6
-
10
-
-
0026082873
-
New, long-acting, potent bradykinin antagonists
-
Lembeck F, Griesbacher T, Eckhardt M, Menke S, Breipohl G, Knolle J New, long-acting, potent bradykinin antagonists. Br J Pharmacol 1991, 102:297-304.
-
(1991)
Br J Pharmacol
, vol.102
, pp. 297-304
-
-
Lembeck, F.1
Griesbacher, T.2
Eckhardt, M.3
Menke, S.4
Breipohl, G.5
Knolle, J.6
-
12
-
-
84882888662
-
-
Marceau F. Personal communication.
-
Marceau F. Personal communication.
-
-
-
-
13
-
-
0032748935
-
Franck Pharmacological profile of LF 16-0687, a new potent non-peptide bradykinin antagonist
-
Pruneau D, Paquet JL, Luccarini JM, Defrêne E, Fouchet C, Franck, et al. Pharmacological profile of LF 16-0687, a new potent non-peptide bradykinin antagonist. Immunopharmacol 1999, 43:187-194.
-
(1999)
Immunopharmacol
, vol.43
, pp. 187-194
-
-
Pruneau, D.1
Paquet, J.L.2
Luccarini, J.M.3
Defrêne, E.4
Fouchet, C.5
-
15
-
-
4444315533
-
Potent and orally bioavailable nonpeptide antagonists at the human bradykinin B1 receptor
-
Ritchie TJ, Dzaidulewicz EK, Culshaw AJ, Muller W, Burgess GM, Bloomfield GC, et al. Potent and orally bioavailable nonpeptide antagonists at the human bradykinin B1 receptor. J Med Chem 2004, 47:4642-4644.
-
(2004)
J Med Chem
, vol.47
, pp. 4642-4644
-
-
Ritchie, T.J.1
Dzaidulewicz, E.K.2
Culshaw, A.J.3
Muller, W.4
Burgess, G.M.5
Bloomfield, G.C.6
-
16
-
-
11144355212
-
-
Gougat J, Ferrari BSL, Planchenault C, Poncelet M, Mauani J, Alonso R, et al. J Pharmacol Exp Therap 2004, 309:661-669.
-
(2004)
J Pharmacol Exp Therap
, vol.309
, pp. 661-669
-
-
Gougat, J.1
Ferrari, B.S.L.2
Planchenault, C.3
Poncelet, M.4
Mauani, J.5
Alonso, R.6
-
17
-
-
0027220896
-
Design of potent, non-peptide antagonists of the human bradykinin B2 receptor
-
Salvino JM, Seoane PR, Douty BD, Awad MMA, Dolle RE, Houck WT, et al. Design of potent, non-peptide antagonists of the human bradykinin B2 receptor. J Med Chem 1993, 36:2583-2584.
-
(1993)
J Med Chem
, vol.36
, pp. 2583-2584
-
-
Salvino, J.M.1
Seoane, P.R.2
Douty, B.D.3
Awad, M.M.A.4
Dolle, R.E.5
Houck, W.T.6
-
18
-
-
0141649387
-
Bradykinin antagonists as anti-cancer agents
-
Stewart JM Bradykinin antagonists as anti-cancer agents. Curr Pharmaceut Design 2003, 9:2036-2042.
-
(2003)
Curr Pharmaceut Design
, vol.9
, pp. 2036-2042
-
-
Stewart, J.M.1
-
19
-
-
0030748582
-
Potent, long-acting, orally active bradykinin antagonists for a wide variety of applications
-
Stewart JM, Gera L, Chan DC, Whalley ET, Hanson WL, Zuzack JS Potent, long-acting, orally active bradykinin antagonists for a wide variety of applications. Immunopharmacol 1997, 36:167-172.
-
(1997)
Immunopharmacol
, vol.36
, pp. 167-172
-
-
Stewart, J.M.1
Gera, L.2
Chan, D.C.3
Whalley, E.T.4
Hanson, W.L.5
Zuzack, J.S.6
-
20
-
-
22544471499
-
Combination cancer chemotherapy with one compound: pluripotent bradykinin antagonists
-
Stewart JM, Gera L, Chan DC, York EJ, Simkeviciene V, Bunn PA, et al. Combination cancer chemotherapy with one compound: pluripotent bradykinin antagonists. Peptides 2005, 26:1288-1291.
-
(2005)
Peptides
, vol.26
, pp. 1288-1291
-
-
Stewart, J.M.1
Gera, L.2
Chan, D.C.3
York, E.J.4
Simkeviciene, V.5
Bunn, P.A.6
-
21
-
-
0030175967
-
A new generation of bradykinin antagonists
-
Stewart JM, Gera L, Hanson W, Zuzack JS, Burkard M, McCullough R, et al. A new generation of bradykinin antagonists. Immunopharmacol 1996, 33:51-60.
-
(1996)
Immunopharmacol
, vol.33
, pp. 51-60
-
-
Stewart, J.M.1
Gera, L.2
Hanson, W.3
Zuzack, J.S.4
Burkard, M.5
McCullough, R.6
-
22
-
-
22544441298
-
Treatment of severe pulmonary hypertension: a bradykinin receptor 2 agonist B9972 causes reduction of pulmonary artery pressure and right ventricular hypertrophy
-
Taraseviciene-Stewart L, Scerbavicius R, Stewart JM, Gera L, Demura Y, Cool C, et al. Treatment of severe pulmonary hypertension: a bradykinin receptor 2 agonist B9972 causes reduction of pulmonary artery pressure and right ventricular hypertrophy. Peptides 2005, 26:1292-1300.
-
(2005)
Peptides
, vol.26
, pp. 1292-1300
-
-
Taraseviciene-Stewart, L.1
Scerbavicius, R.2
Stewart, J.M.3
Gera, L.4
Demura, Y.5
Cool, C.6
-
23
-
-
0021877149
-
Competitive antagonists of bradykinin
-
Vavrek RJ, Stewart JM Competitive antagonists of bradykinin. Peptides 1985, 6:161-164.
-
(1985)
Peptides
, vol.6
, pp. 161-164
-
-
Vavrek, R.J.1
Stewart, J.M.2
-
24
-
-
0035975941
-
Bradykinin contributes to the vasodilator effects of chronic angiotensin-converting enzyme inhibition in patients with heart failture
-
Witherow FN, Helmy A, Webb DJ, Fox KAA, Newby DE Bradykinin contributes to the vasodilator effects of chronic angiotensin-converting enzyme inhibition in patients with heart failture. Circulation 2001, 104:2177-2181.
-
(2001)
Circulation
, vol.104
, pp. 2177-2181
-
-
Witherow, F.N.1
Helmy, A.2
Webb, D.J.3
Fox, K.A.A.4
Newby, D.E.5
-
25
-
-
0024469966
-
Multiple neuropeptides mobilize calcium in small cell lung cancer: effects of vasopressin, bradykinin, cholecystokinin, galanin and neurotensin
-
Woll PJ, Rozengurt E Multiple neuropeptides mobilize calcium in small cell lung cancer: effects of vasopressin, bradykinin, cholecystokinin, galanin and neurotensin. Biochem Biophys Res Commun 1989, 164:66-73.
-
(1989)
Biochem Biophys Res Commun
, vol.164
, pp. 66-73
-
-
Woll, P.J.1
Rozengurt, E.2
|