Leupeptin inhibits ventilator-induced diaphragm dysfunction in rats

American Journal of Respiratory and Critical Care Medicine

Volumn 175, Issue 11, 2007, Pages 1134-1138

  Maes, Karen ^a   Testelmans, Dries ^a   Powers, Scott ^b   Decramer, Marc ^a   Gayan Ramirez, Ghislaine ^a,c  

^a UNIVERSITY OF LEUVEN   (Belgium)

^b UNIVERSITY OF FLORIDA   (United States)

^c Labo Ademspieren   (Belgium)

Author keywords

Mechanical ventilation; Protein degradation; Respiratory muscles

Indexed keywords

CALPAIN; CALPASTATIN; CATHEPSIN B; LEUPEPTIN; LYSOSOME ENZYME; PROTEINASE; SODIUM CHLORIDE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ARTIFICIAL VENTILATION; COMPARATIVE STUDY; CONTROL GROUP; CONTROLLED STUDY; DIAPHRAGM; DIAPHRAGM DISEASE; DRUG INHIBITION; ENZYME ACTIVITY; FIBER; FORCE; IN VITRO STUDY; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; RAT; STATISTICAL SIGNIFICANCE; STIMULATION; VENTILATOR;

6-MERCAPTOPURINE; ANIMALS; BLOTTING, WESTERN; CALPAIN; CATHEPSIN B; DIAPHRAGM; DISEASE MODELS, ANIMAL; FLUOROMETRY; MALE; MUSCLE CONTRACTION; MUSCULAR DISEASES; NUCLEIC ACID SYNTHESIS INHIBITORS; RATS; RATS, WISTAR; RESPIRATION, ARTIFICIAL; TREATMENT OUTCOME;

EID: 34249785106     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200609-1342OC     Document Type: Article

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