Macrofilaricidal activity in Wuchereria bancrofti after 2 weeks treatment with a combination of rifampicin plus doxycycline

Journal of Parasitology Research

Volumn 2011, Issue , 2011, Pages

  Hoerauf, Achim ^c   Debrah, Alexander Yaw ^a,b   Mand, Sabine ^c   Marfo Debrekyei, Yeboah ^b   Batsa, Linda ^b   Albers, Anna ^c   Specht, Sabine ^c   Klarmann, Ute ^c   Pfarr, Kenneth ^c   Adjei, Ohene ^a  

^a KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Ghana)

^b KUMASI CENTRE FOR COLLABORATIVE RESEARCH IN TROPICAL MEDICINE   (Ghana)

^c UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DOXYCYCLINE; PLACEBO; RIFAMPICIN;

ADULT; ANTHELMINTIC ACTIVITY; ANTIGENICITY; ARTICLE; BANCROFTIAN FILARIASIS; CLINICAL ARTICLE; CONTROLLED STUDY; COUGHING; DIZZINESS; DRUG INDUCED HEADACHE; DRUG RESPONSE; GHANA; HUMAN; MACROFILARICIDAL ACTIVITY; MALE; MICROFILARIA; NAUSEA; NONHUMAN; PARASITE LOAD; PILOT STUDY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; STOMACH PAIN; TREATMENT DURATION; TREATMENT OUTCOME; WUCHERERIA BANCROFTI;

WOLBACHIA; WUCHERERIA BANCROFTI;

EID: 80052648057     PISSN: 20900023     EISSN: 20900031     Source Type: Journal    
DOI: 10.1155/2011/201617     Document Type: Article

References (36)

1. WHO, Annual report on lymphatic filariasis. October 2005, http://www.filariasis.org/
2. WHO, Meeting of the international task force for disease eradication11 January 2007 Weekly Epidemiological Record 2007 82 197 208
3. WHO, Global programme to eliminate lymphatic filariasis. Progress report on mass drug administrations in 2006 Weekly Epidemiological Record 2007 82 361 380
4. WHO, Global programme to eliminate lymphatic filariasis. Progress report on mass drug administrations in 2009 Weekly Epidemiological Record 2010 85 365 372
5. Awadzi K., Attah S. K., Addy E. T., Opoku N. O., Quartey B. T., The effects of high-dose ivermectin regimens on Onchocerca volvulus in onchocerciasis patients Transactions of the Royal Society of Tropical Medicine and Hygiene 1999 93 2 189 194 (Pubitemid 29233861)
6. Ottesen E. A., Duke B. O. L., Karam M., Behbehani K., Strategies and tools for the control/elimination of lymphatic filariasis Bulletin of the World Health Organization 1997 75 6 491 503 (Pubitemid 28099975)
7. Nores J., Dreyer G., Santos A., Mendes V. G., Medeiros Z., Addiss D., Assessment of the efficacy of diethylcarbamazine on adult Wuchereria bancrofti in vivo Transactions of the Royal Society of Tropical Medicine and Hygiene 1997 91 1 78 81 (Pubitemid 27095509)
8. Critchley J., Addiss D., Gamble C., Garner P., Gelband H., Ejere H., Albendazole for lymphatic filariasis Cochrane Database of Systematic Reviews 2005 4
9. Gyapong J. O., Kumaraswami V., Biswas G., Ottesen E. A., Treatment strategies underpinning the global programme to eliminate lymphatic filariasis Expert Opinion on Pharmacotherapy 2005 6 2 179 200 (Pubitemid 40305333)
10. Dreyer G., Addiss D., Williamson J., Nores J., Efficacy of co-administered diethylcarbamazine and albendazole against adult Wuchereria bancrofti Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 100 12 1118 1125 (Pubitemid 44478725)
11. Hoerauf A., Volkmann L., Hamelmann C., Adjei O., Autenrieth I. B., Fleischer B., Bttner D. W., Endosymbiotic bacteria in worms as targets for a novel chemotherapy in filariasis The Lancet 2000 355 9211 1242 1243 (Pubitemid 30184538)
12. Hoerauf A., Mand S., Adjei O., Fleischer B., Bttner D. W., Depletion of Wolbachia endobacteria in Onchcerca volvulus by doxycycline and microfilaridermia after ivermectin treatment The Lancet 2001 357 1415 1416 (Pubitemid 32455374)
13. Hoerauf A., Specht S., Marfo-Debrekyei Y., Bttner M., Debrah A. Y., Mand S., Batsa L., Brattig N., Konadu P., Bandi C., Fimmers R., Adjei O., Bttner D. W., Efficacy of 5-week doxycycline treatment on adult Onchocerca volvulus Parasitology Research 2009 104 2 437 447
14. Debrah A. Y., Mand S., Marfo-Debrekyei Y., Larbi J., Adjei O., Hoerauf A., Assessment of microfilarial loads in the skin of onchocerciasis patients after treatment with different regimens of doxycycline plus ivermectin Filaria Journal 2006 5, article 1
15. Taylor M. J., Makunde W. H., McGarry H. F., Turner J. D., Mand S., Hoerauf A., Macrofilaricidal activity after doxycycline treatment of Wuchereria bancrofti: a double-blind, randomised placebo-controlled trial The Lancet 2005 365 9477 2116 2121 (Pubitemid 40826969)
16. Debrah A. Y., Mand S., Specht S., Marfo-Debrekyei Y., Batsa L., Pfarr K., Larbi J., Lawson B., Taylor M., Adjei O., Hoerauf A., Doxycycline reduces plasma VEGF-C/sVEGFR-3 and improves pathology in lymphatic filariasis PLoS Pathogens 2006 2 9, article e92
17. Debrah A. Y., Mand S., Marfo-Debrekyei Y., Batsa L., Pfarr K., Buttner M., Adjei O., Buttner D., Hoerauf A., Macrofilaricidal effect of 4 weeks of treatment with doxycycline on Wuchereria bancrofti Tropical Medicine and International Health 2007 12 12 1433 1441 (Pubitemid 350212708)
18. Debrah A. Y., Mand S., Marfo-Debrekyei Y., Batsa L., Pfarr K., Lawson B., Taylor M., Adjei O., Hoerauf A., Reduction in levels of plasma vascular endothelial growth factor-A and improvement in hydrocele patients by targeting endosymbiotic Wolbachia sp. in Wuchereria bancrofti with doxycycline American Journal of Tropical Medicine and Hygiene 2009 80 6 956 963
19. Turner J. D., Mand S., Debrah A. Y., Muehlfeld J., Pfarr K., McGarry H. F., Adjei O., Taylor M. J., Hoerauf A., A randomized, double-blind clinical trial of a 3-week course of doxycycline plus albendazole and ivermectin for the treatment of Wuchereria bancrofti infection Clinical Infectious Diseases 2006 42 8 1081 1089
20. Mand S., Pfarr K., Sahoo P. K., Satapathy A. K., Specht S., Klarmann U., Debrah A. Y., Ravindran B., Hoerauf A., Macrofilaricidal activity and amelioration of lymphatic pathology in bancroftian filariasis after 3 weeks of doxycycline followed by single-dose diethylcarbamazine American Journal of Tropical Medicine and Hygiene 2009 81 4 702 711
21. Townson S., Hutton D., Siemienska J., Hollick L., Scanlon T., Tagboto S. K., Taylor M. J., Antibiotics and Wolbachia in filarial nematodes: antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi Annals of Tropical Medicine and Parasitology 2000 94 8 801 816 (Pubitemid 32102491)
22. Rao R., Weil G. J., In vitro effects of antibiotics on Brugia malayi worm survival and reproduction Journal of Parasitology 2002 88 3 605 611 (Pubitemid 34686529)
23. Volkmann L., Fischer K., Taylor M., Hoerauf A., Antibiotic therapy in murine filariasis (Litomosoides sigmodontis): comparative effects of doxycycline and rifampicin on Wolbachia and filarial viability Tropical Medicine and International Health 2003 8 5 392 401 (Pubitemid 36733588)
24. Specht S., Mand S., Marfo-Debrekyei Y., Debrah A. Y., Konadu P., Adjei O., Bttner D. W., Hoerauf A., Efficacy of 2- and 4-week rifampicin treatment on the Wolbachia of Onchocerca volvulus Parasitology Research 2008 103 6 1303 1309
25. Hoerauf A., Mand S., Fischer K., Kruppa T., Marfo-Debrekyei Y., Debrah A. Y., Pfarr K. M., Adjei O., Bttner D. W., Doxycycline as a novel strategy against bancroftian filariasis-depletion of Wolbachia endosymbionts from Wuchereria bancrofti and stop of microfiariae production Medical Microbiology and Immunology 2003 192 4 211 216 (Pubitemid 37491681)
26. Mand S., Marfo-Debrekyei Y., Dittrich M., Fischer K., Adjei O., Hoerauf A., Animated documentation of the filaria dance sign (FDS) in bancroftian filariasis Filaria Journal 2003 2, article 3
27. Dreyer G., Brando A. C., Amaral F., Medeiros Z., Addiss D., Detection by ultrasound of living adult Wuchereria bancrofti in the female breast Memrias do Instituto Oswaldo Cruz 1996 91 1 95 96
28. Mand S., Bttner D. W., Hoerauf A., Bancroftian filariasisabsence of Wolbachia after doxycycline treatment American Journal of Tropical Medicine and Hygiene 2008 78 6 854 855 (Pubitemid 351967798)
29. Kshirsagar N. A., Gogtay N. J., Garg B. S., Deshmukh P. R., Rajgor D. D., Kadam V. S., Kirodian B. G., Ingole N. S., Mehendale A. M., Fleckenstein L., Karbwang J., Lazdins-Helds J. K., Safety, tolerability, efficacy and plasma concentrations of diethylcarbamazine and albendazole co-administration in a field study in an area endemic for lymphatic filariasis in India Transactions of the Royal Society of Tropical Medicine and Hygiene 2004 98 4 205 217 (Pubitemid 38950414)
30. Nores J., Dreyer G., Santos A., Mendes V. G., Medeiros Z., Addiss D., Assessment of the efficacy of diethylcarbamazine on adult Wuchereria bancrofti in vivo Transactions of the Royal Society of Tropical Medicine and Hygiene 1997 91 1 78 81 (Pubitemid 27095509)
31. Ottesen E. A., Duke B. O. L., Karam M., Behbehani K., Strategies and tools for the control/elimination of lymphatic filariasis Bulletin of the World Health Organization 1997 75 6 491 503 (Pubitemid 28099975)
32. Hussein O., El Setouhy M., Ahmed E. S., Kandil A. M., Ramzy R. M. R., Helmy H., Weil G. J., Duplex Doppler sonographic assessment of the effects of diethylcarbamazine and albendazole therapy on adult filarial worms and adjacent host tissues in bancroftian filariasis American Journal of Tropical Medicine and Hygiene 2004 71 4 471 477 (Pubitemid 39458341)
33. Dreyer G., Addiss D., Williamson J., Nores J., Efficacy of co-administered diethylcarbamazine and albendazole against adult Wuchereria bancrofti Transactions of the Royal Society of Tropical Medicine and Hygiene 2006 100 12 1118 1125 (Pubitemid 44478725)
34. Hoerauf A., New strategies to combat filariasis Expert Review of Anti-Infective Therapy 2006 4 2 211 222
35. Hoerauf A., Filariasis: new drugs and new opportunities for lymphatic filariasis and onchocerciasis Current Opinion in Infectious Diseases 2008 21 6 673 681
36. Taylor M. J., Hoerauf A., Bockarie M., Lymphatic filariasis and onchocerciasis The Lancet 2010 376 9747 1175 1185