Further insights into the antinociceptive potential of a peptide disrupting the N-type calcium channel-CRMP-2 signaling complex

Channels

Volumn 5, Issue 5, 2011, Pages 449-456

  Wilson, Sarah M ^a   Brittain, Joel M ^a   Piekarz, Andrew D ^a   Ballard, Carrie J ^a   Ripsch, Matthew S ^a   Cummins, Theodore R ^a   Hurley, Joyce H ^a   Khanna, May ^a   Hammes, Nathan M ^a   Samuels, Brian C ^a   White, Fletcher A ^a   Khanna, Rajesh ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Chronic pain; CRMP 2; Migraine; Pain therapeutics; Peptide

Indexed keywords

ANTINOCICEPTIVE AGENT; CALCIUM CHANNEL N TYPE; COLLAPSIN RESPONSE MEDIATOR PROTEIN 2; LYSOPHOSPHATIDYLCHOLINE; OMEGA CONOTOXIN MVIIA; PEPTIDE DERIVATIVE; TRANSACTIVATOR OF TRANSCRIPTION CBD3 PEPTIDE; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; ARTICLE; CALCIUM SIGNALING; CHRONIC PAIN; CONTROLLED STUDY; DEMYELINATION; DRUG EFFICACY; DRUG PROTEIN BINDING; DRUG RESPONSE; DRUG SAFETY; FEMALE; MIGRAINE; NERVE INJURY; NEUROPATHIC PAIN; NONHUMAN; PROTEIN PROTEIN INTERACTION; RAT; SCIATIC NERVE; SINGLE DRUG DOSE; TIBIAL NERVE; TRANQUILIZING ACTIVITY;

ANIMALIA; RODENTIA;

EID: 80052635029     PISSN: 19336950     EISSN: 19336969     Source Type: Journal    
DOI: 10.4161/chan.5.5.17363     Document Type: Article

References (35)

1. Park J, Luo ZD. Calcium channel functions in pain processing. Channels (Austin) 2010; 4:510-7.
2. Callaghan B, Adams DJ. Analgesic alpha-conotoxins Vc1.1 and RgIA inhibit N-type calcium channels in sensory neurons of alpha9 nicotinic receptor knockout mice. Channels (Austin) 2010; 4:51-4.
3. Brittain JM, Piekarz AD, Wang Y, Kondo T, Cummins TR, Khanna R. An atypical role for collapsin response mediator protein 2 (CRMP-2) in neurotransmitter release via interaction with presynaptic voltage-gated calcium channels. J Biol Chem 2009; 284:31375-90.
4. v2.2) and transmitter release by collapsin response mediator protein-2 (CRMP-2) in sensory neurons. J Cell Sci 2009; 122:4351-62.
5. Wang Y, Brittain JM, Wilson SM, Khanna R. Emerging roles of collapsin response mediator proteins (CRMPs) as regulators of voltage-gated calcium channels and synaptic transmission. Commun Integr Biol 2010; 3:172-5.
6. 2+ channel complex. Nat Med 2011; 17:822-9.
7. Talkington M. Curbing a Calcium Channel. Pain Research Forum. Boston 2011; http://www.pain-researchforum.org/news/7026-curbing-calcium-channel.
8. Whalley K. Pain: Blocking painful interactions. Nat Rev Neurosci 2011; DOI:10.1038/nrn3069.
9. Schmidtko A, Lotsch J, Freynhagen R, Geisslinger G. Ziconotide for treatment of severe chronic pain. Lancet 2010; 375:1569-77.
10. McGivern JG. Ziconotide: a review of its pharmacology and use in the treatment of pain. Neuropsychiatr Dis Treat 2007; 3:69-85. (Pubitemid 46779923)
11. Snutch TP. Targeting chronic and neuropathic pain: the N-type calcium channel comes of age. NeuroRx 2005; 2:662-70. (Pubitemid 41393273)
12. 2+ channel. EMBO J 2001; 20:2349-56.
13. Fabi F, Chiavarelli M, Argiolas L, Chiavarelli R, del Basso P. Evidence for sympathetic neurotransmission through presynaptic N-type calcium channels in human saphenous vein. Br J Pharmacol 1993; 110:338-42. (Pubitemid 23257801)
14. 2+ channels in evoked release of norepinephrine from sympathetic neurons. Science 1988; 239:57-61.
15. Wang YX, Bezprozvannaya S, Bowersox SS, Nadasdi L, Miljanich G, Mezo G, et al. Peripheral versus central potencies of N-type voltage-sensitive calcium channel blockers. Naunyn Schmiedebergs Arch Pharmacol 1998; 357:159-68. (Pubitemid 28085516)
16. Bowersox SS, Singh T, Nadasdi L, Zukowska-Grojec Z, Valentino K, Hoffman BB. Cardiovascular effects of omega-conopeptides in conscious rats: mechanisms of action. J Cardiovasc Pharmacol 1992; 20:756-64.
17. Bean BP. Comment by Bruce P. Bean on: Megan Talkington. Curbing a Calcium Channel. Pain Research Forum. 24 June 2011.
18. Radtke C, Vogt PM, Devor M, Kocsis JD. Keratinocytes acting on injured afferents induce extreme neuronal hyperexcitability and chronic pain. Pain 2010; 148:94-102.
19. 2+ channel complex. Nat Med 2011; 17:822-9]. Faculty of 1,000: 2011 F1000com/11419957: Faculty of 1,000, 2011.
20. White DM, Cousins MJ. Effect of subcutaneous administration of calcium channel blockers on nerve injury-induced hyperalgesia. Brain Res 1998; 801:50-8. (Pubitemid 28401645)
21. Al-Hallaq RA, Conrads TP, Veenstra TD, Wenthold RJ. NMDA di-heteromeric receptor populations and associated proteins in rat hippocampus. J Neurosci 2007; 27:8334-43. (Pubitemid 47219608)
22. Omote K, Kawamata T, Kawamata M, Namiki A. Formalin-induced release of excitatory amino acids in the skin of the rat hind paw. Brain Res 1998; 787:161-4. (Pubitemid 28279815)
23. Davidson EM, Coggeshall RE, Carlton SM. Peripheral NMDA and non-NMDA glutamate receptors contribute to nociceptive behaviors in the rat formalin test. Neuroreport 1997; 8:941-6. (Pubitemid 27152151)
24. Joseph EK, Chen X, Khasar SG, Levine JD. Novel mechanism of enhanced nociception in a model of AIDS therapy-induced painful peripheral neuropathy in the rat. Pain 2004; 107:147-58. (Pubitemid 38058710)
25. Bhangoo SK, Ren D, Miller RJ, Chan DM, Ripsch MS, Weiss C, et al. CXCR4 chemokine receptor signaling mediates pain hypersensitivity in association with antiretroviral toxic neuropathy. Brain Behav Immun 2007; 21:581-91. (Pubitemid 46829778)
26. Wallace VCJ, Cottrell DF, Brophy PJ, Fleetwood-Walker SM. Focal lysolecithin-induced demyelination of peripheral afferents results in neuropathic pain behavior that is attenuated by cannabinoids. J Neurosci 2003; 23:3221-33. (Pubitemid 36531963)
27. Bhangoo S, Ren D, Miller RJ, Henry KJ, Lineswala J, Hamdouchi C, et al. Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors. Mol Pain 2007; 3:38.
28. Lee BH, Won R, Baik EJ, Lee SH, Moon CH. An animal model of neuropathic pain employing injury to the sciatic nerve branches. Neuroreport 2000; 11:657-61. (Pubitemid 30173900)
29. Jaggi AS, Jain V, Singh N. Animal models of neuropathic pain. Fundam Clin Pharmacol 2011; 25:1-28.
30. Kunkler PE, Ballard CJ, Oxford GS, Hurley JH. TRPA1 receptors mediate environmental irritant-induced meningeal vasodilatation. Pain 2011; 152:38-44.
31. Wang Y, Wilson SM, Brittain JM, Ripsch MS, Salome C, Park KD, et al. Merging structural motifs of functionalized amino acids and α-aminoamides results in novel anticonvulsant compounds with significant effects on slow and fast inactivation of voltage-gated sodium channels and in the treatment of neuropathic pain. ACS Chemical Neuroscience 2011; 2:317-32.
32. Pavlidis P, Noble WS. Matrix2png: a utility for visualizing matrix data. Bioinformatics 2003; 19:295-6. (Pubitemid 36181920)
33. Valentino K, Newcomb R, Gadbois T, Singh T, Bowersox S, Bitner S, et al. A selective N-type calcium channel antagonist protects against neuronal loss after global cerebral ischemia. Proc Natl Acad Sci USA 1993; 90:7894-7. (Pubitemid 23250057)
34. Malmberg AB, Gilbert H, McCabe RT, Basbaum AI. Powerful antinociceptive effects of the cone snail venom-derived subtype-selective NMDA receptor antagonists conantokins G and T. Pain 2003; 101:109-16. (Pubitemid 36044658)
35. Malmberg AB, Yaksh TL. Voltage-sensitive calcium channels in spinal nociceptive processing: blockade of N- and P-type channels inhibits formalin-induced nociception. J Neurosci 1994; 14:4882-90. (Pubitemid 24237910)