Benzofuranone Derivatives as Effective Small Molecules Related to Insulin Amyloid Fibrillation: A Structure-Function Study

Chemical Biology and Drug Design

Volumn 78, Issue 4, 2011, Pages 659-666

  Rabiee, Atefeh ^a   Ebrahim Habibi, Azadeh ^b   Navidpour, Latifeh ^c   Morshedi, Dina ^d   Ghasemi, Atiyeh ^e   Sabbaghian, Marjan ^f   Nemati Lay, Maryam ^a   Nemat Gorgani, Mohsen ^e,g  

^a ISLAMIC AZAD UNIVERSITY   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

^e UNIVERSITY OF TEHRAN   (Iran)

^f ROYAN INSTITUTE FOR REPRODUCTIVE BIOMEDICINE   (Iran)

^g STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aggregation; Amyloid; Benzufuranone; Bovine insulin; Inhibition

Indexed keywords

3 BENZOFURANONE DERIVATIVE; 6 METHOXY 2 (5 NITROFURAN 2 YLMETHYLENE) 3 (2H)BENZOFURANONE; 6 METHOXY 2 (5 NITROTHIOPHENE 2 YLMETHYLENE) 3 (2H)BENZOFURANONE; 6,7 DIMETHOXY 2 (5 NITROFURAN 2 YLMETHYLENE) 3 (2H)BENZOFURANONE; 6,7 DIMETHOXY 2 (5 NITROTHIOPHENE 2 YLMETHYLENE) 3(2H)BENZOFURANONE; AMYLOID; CONGO RED; INSULIN; THIOFLAVINE; UNCLASSIFIED DRUG;

ARTICLE; CIRCULAR DICHROISM; CONTROLLED STUDY; DRUG BINDING; ELECTRON MICROSCOPY; FLUORESCENCE; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN DEGRADATION; PROTEIN FIBRILLATION; PROTEIN INTERACTION;

AMYLOID; ANIMALS; BENZOFURANS; CATTLE; INSULIN; MODELS, MOLECULAR; PROTEIN BINDING;

BOVINAE;

EID: 80052633780     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01197.x     Document Type: Article

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