Synthesis of a carbon-14 labelled version of benzofuran GR151004B

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 38, Issue 9, 1996, Pages 863-871

  Wadsworth, Alan H ^a   Mitchell, Heather A ^a   Fellows, Lan ^a   Sutherland, Derek R ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Benzofuran; Carbon 14

Indexed keywords

A-CARBON; BENZOFURANS; CARBON 14;

CARBON;

2 [5 [3 (2 DIMETHYLAMINOETHYL)BENZOFURAN 3 YL] 3 PYRIDYL] 1 (4 MORPHOLINYL)ETHANONE; BENZOFURAN DERIVATIVE; CARBON 14; GR 151004B; SEROTONIN 1 AGONIST; UNCLASSIFIED DRUG;

ARTICLE; DRUG SYNTHESIS; ISOTOPE LABELING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOCHEMISTRY; REACTION ANALYSIS;

EID: 0029760233     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199609)38:9<863::AID-JLCR895>3.0.CO;2-0     Document Type: Article

References (9)

1. North P.C., Oxford A.W., Feniuk W., Humphrey P.P.A., and Connor H.E., in 'Medicinal Chemistry: Principles and Practice' (Ed. King F.D.), The Royal Society of Chemistry, 1994, 265.
2. North P.C. and Wadman S.N., International Patent Application WO 94/08993.
3. Jung M.E. and Abrecht S., J. Org. Chem., 1988, 53, 423.
4. Croce P.D., Ann. Chim. (Rome). 1973, 63, 867
5. Sansoulet J. and Welvart Z., Bull. Soc. Chim. Fr., 1962, 77
6. Brown H.C. and Krishnamurthy S.J., J. Org. Chem., 1969, 34, 3918.
7. Yoon N.M. and Brown H.C., J. Am. Chem. Soc., 1968, 90, 2927.
8. Yoon N.M. and Gyoung Y.S., J. Org. Chem., 1985, 50, 2443.
9. Malm J., Björk P., Gronowitz S., and Hörnfeldt A.-B., Tetrahedron Letters, 1992, 33, 2199.