Inhibition of endoplasm reticulum stress by anisodamine protects against myocardial injury after cardiac arrest and resuscitation in rats

American Journal of Chinese Medicine

Volumn 39, Issue 5, 2011, Pages 853-866

  Yin, Xue Lian ^a   Shen, Hong ^a   Zhang, Wei ^a   Yang, Yang ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Anisodamine; Cardiac Arrest; Endoplasmic Reticulum Stress; Resuscitation

Indexed keywords

ADRENALIN; ANISODAMINE; CASPASE 3; CCAAT ENHANCER BINDING PROTEIN; GLUCOSE REGULATED PROTEIN 78;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENDOPLASMIC RETICULUM STRESS; HEART ARREST; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART PROTECTION; MALE; NONHUMAN; PROTEIN EXPRESSION; RAT; RESUSCITATION; RETURN OF SPONTANEOUS CIRCULATION; SURVIVAL RATE;

ANIMALS; APOPTOSIS; CARDIOPULMONARY RESUSCITATION; DISEASE MODELS, ANIMAL; DOWN-REGULATION; DRUGS, CHINESE HERBAL; ENDOPLASMIC RETICULUM STRESS; HEART ARREST; HEART INJURIES; HUMANS; MALE; MYOCARDIUM; RANDOM ALLOCATION; RATS; REPERFUSION INJURY; SOLANACEOUS ALKALOIDS;

EID: 80052628920     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X11009251     Document Type: Article

References (37)

1. Brodsky, J.L. The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation). Biochem. J. 404(3): 353-363, 2007. (Pubitemid 46953909)
2. Chen, J.B., C.X. Huang, Q.Z. Tang, J.J. Li, J.L. Xu, J.M. Wang and G.S. Li. The effect of anisodamine on the L-type calcium channel in ventricular myocytes of rabbit. Chin. Pharmacol. Bull. 16(2): 162-164, 2000.
3. Ding, C., X.-H. Fu, J.-X. Li, Z. Li, H.-X. Chen, Y.-Y. Zhao and J.-A. Sun. Effects of Anisodamine on the area of myocardial infarction in reperfusion injured rabbits after acute myocardial infarction. Med. J. Natl. Defend. Forces North China 20(6): 12-14, 2008.
4. Fries, M, M.H. Weil, Y.T. Chang, C. Castillo and W.C. Tang. Microcirculation during cardiac arrest and resuscitation. Crit. Care Med. 34(Suppl.): S454-S457, 2006. (Pubitemid 44772681)
5. Fu, X.H., W.Z. Fan, X.S. Gu, Y.Y. Wei, Y.F. Jiang, W.L. Wu, S.H. Li, G.Z. Hao, Q.M. Wei and L. Xue. Effect of intracoronary administration of anisodamine on slow reflow phenomenon following primary percutaneous coronary intervention in patients with acute myocardial infarction. Chin. Med. J. 120(14): 1226-1231, 2007. (Pubitemid 47232905)
6. Giorgi, C., D.D. Stefania, A. Bononia, R. Rizzutoc and P. Pintona. Structural and functional link between the mitochondrial network and the endoplasmic reticulum Int. J. Biochem. Cell Biol. 41: 1817-1827, 2009.
7. Glembotski, C.C. The role of the unfolded protein response in the heart. J. Mol. Cell Cardiol. 44: 453-459, 2008. (Pubitemid 351374700)
8. Gotoh, T., M. Endo and Y. Oike. Endoplasmic reticulum stress-induced transcriptional factor chop and cardiovascular diseases. Curr. Hypertens. Rev. 6: 55-65, 2010.
9. Huang, Y.S., A. Li and Z.C. Yang. Roles of thromboxane and its inhibitor anisodamine in burn shock. Burns 16(4): 249-253, 1990.
10. Jia, L.J. and H. Shen. Intervention of anisodamine on cardiac pathology and microcirculation during resuscitation. Int. J. Emerg. Crit. Care Med. 4(3): 1843-1844, 2007.
11. Jia, L.J., W. Chen, H. Shen, D. Ji, X.M. Zhao and X.H. Liu. Effects of anisodamine on microcirculation of the asystole rats during the cardiopulmonary resuscitation. Chin. Crit. Care Med. 20(12): 737-739, 2008.
12. Kern, K.B., M. Zuercher, D. Cragun, S. Ly, J. Quash, S. Bhartia, R.W. Hilwig, R.A. Berg and G.A. Ewy. Myocardial microcirculatory dysfunction after prolonged ventricular fibrillation and resuscitation. Crit. Care Med. 36: S418-S421, 2008.
13. Li, J. and A.S. Lee. Stress induction of GRP78/BiP and its role in cancer. Curr. Mol. Med. 6(1): 45-54, 2006.
14. Liu, C., F.M. Shen, Y.Y. Le, Y. Kong, X. Liu, G.J. Cai, A.F. Chen and D.F. Su. Antishock effect of anisodamine involves a novel pathway for activating alpha7 nicotinic acetylcholine receptor. Crit. Care Med. 37(2): 634-641, 2009.
15. Liu, Y., Q. Wang, X. Zhu, D. Liu, S. Pan, Y. Ruan and Y. Li. Pulmonary artery perfusion with protective solution reduces lung injury after cardiopulmonary bypass. Ann. Thorac. Surg. 69(5): 1402-1407, 2000. (Pubitemid 30434866)
16. Luo, Z.Y., Y. Tang, J.I. You and H. Luo. Protective effect of anisodamine on cultured bovine pulmonary endothelial cell injury induced by oxygen-free radicals. Arch. Surg. 127(10): 1204-1208, 1992.
17. Montie, H.L., A.J. Haezebrouck, J.C. Gutwald and D.J. DeGracia. PERK is activated differentially in peripheral organs following cardiac arrest and resuscitation. Resuscitation 66(3): 379-389, 2005. (Pubitemid 41219388)
18. Ni, M. and A.S. Lee. ER chaperones in mammalian development and human diseases. FEBS Lett. 581(19): 3641-3651, 2007. (Pubitemid 47082516)
19. Nolan, J.P. R.W. Neumar, C. Adrie, M. Aibiki, R.A. Berg, B.W. Böttiger, C. Callaway, R.S. Clark, R.G. Geocadin, E.C. Jauch, K.B. Kern, I. Laurent, W.T. Longstreth, R.M. Merchant, P. Morley, L.J. Morrison, V. Nadkarni, M.A. Peberdy, E.P. Rivers, A. Rodriguez-Nunez, F.W. Sellke, C. Spaulding, K. Sunde and T.V. Hoek. Post-cardiac arrest syndrome: Epidemiology, pathophysiology, treatment, and prognostication. A Scientific Statement from the International Liaison Committee on Resuscitation; the American Heart Association Emergency Cardiovascular Care Committee; the Council on Cardiovascular Surgery and Anesthesia; the Council on Cardiopulmonary, Perioperative, and Critical Care; the Council on Clinical Cardiology; the Council on Stroke. Resuscitation 79(3): 350-379, 2008.
20. Norby, F.L. and J. Ren. Anisodamine inhibits cardiac contraction and intracellular Ca(2+) transients in isolated adult rat ventricular myocytes. Eur. J. Pharmacol. 439(1-3): 21-25, 2002. (Pubitemid 34286602)
21. Okada, K.I., T. Minamino, Y. Tsukamoto, Y.L. Liao, O. Tsukamoto, S.J. Takashima, A. Hirata, M. Fujita, Y. Nagamachi, T. Nakatani, C. Yutani, K. Ozawa, S. Ogawa, H. Tomoike, M. Hori and M. Kitakaze. Prolonged endoplasmic reticulum stress in hypertrophic and failing heart after aortic constriction: Possible contribution of endoplasmic reticulum stress to cardiac myocyte apoptosis. Circulation 110: 705-712, 2004. (Pubitemid 39056270)
22. Oyadomari, S. and M. Mori. Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ. 11: 381-389, 2004. (Pubitemid 38489416)
23. Redding, J.S. and J.W. Pearson. Resuscitation from ventricular fibrillation. Drug therapy. JAMA 203: 255-60, 1968.
24. Ruan, Q.R., J.X. Song and Z.D. Deng. Study on effect of anisodamine on expressions of tissue factor and plasminogen activator-1 inhibitor in vascular endothelial cells and its mechanisms. Chin. J. Integr. Tradit. West. Med. 24(5): 422-426, 2004.
25. Shen, C.X., C. Liang, L.L. Chen, J.Y. Qian, K.Q. Wang, H.Z. Chen and J.B. Guo. Effect of anisodamine on coronary microthrombosis induced by microspheres in rats. J. Southeast Univ. (Med. Sci. Ed.) 22(6): 369-372, 2003.
26. Su, J.Y. Cell protection mechanism of antishock action of anisodamine. Chin. Med. J. 105(12): 976-979, 1992.
27. Sun, J., Z.H. Guo, T.S. Lai, Y.Q. Tang, L. Su, X. Hong and B.L. Mao. An experimental study on the mechanisms of anisodamine in protection against vascular endothelial cellular damages. Bull. Acad. Mil. Med. Sci. 132(2): 137-140, 2008.
28. Szegezdi, E., A. Duffy, M.E. O'Mahoney, S.E. Logue, L.A. Mylotte, T. O'Brien and A. Samali. ER stress contributes to ischemia-induced cardiomyocyte apoptosis. Biochem. Biophys. Res. Commun. 349(4): 1406-1411, 2006. (Pubitemid 44416413)
29. Tang, Y.H., P. Chen, D.R. Hu and G.Y. Deng. The clinical study of anisodamine in myocardial protection. Chin. Crit. Care Med. 13(10): 604-606, 2001.
30. Thuerauf, D.J., M. Marcinko, N. Gude, M. Rubio, M.A. Sussman and C.C. Glembotski. Activation of the unfolded protein response in infarcted mouse heart and hypoxic cultured cardiac myocytes. Circ. Res. 99(3): 275-282, 2006. (Pubitemid 44174935)
31. Wang, P.Y., J.W. Chen and F. Hwang. Anisodamine causes acyl chain interdigitation in phosphatidylglycerol. FEBS Lett. 332(1-2): 193-196, 1993. (Pubitemid 23295926)
32. Xie, J.X., J. Zhou, C.Z. Zhang and J.H. Yang, Synthesis of anisodamine analogs. Acta Pharmacol. Sin. 16(10): 767-772, 1981.
33. Yao, X.J., Y.H. Tan, Z.C. Xu, X.Y. Li and S.Y. Chen. Effects of anisodamine against myocardial ischemia-reperfused injuries and antilipid peroxidation. Acta Pharmacol. Sin. 16(2): 152-155, 1995.
34. Yuan, Y.J., Q.L. Guo, Z. Ye, P.P. Xia, N. Wang and Z.B. Song. Ischemic postconditioning protects brain from ischemia/reperfusion injury by attenuating endoplasmic reticulum stress-induced apoptosis through PI3K-Akt pathway. Brain Res. 1367: 85-93, 2011.
35. Zhang, S., A.M. Chang, C.F. Li, Z.J. Li, Z.J. Yin, X. Zhao and S.L. Liang. Mechanism of the therapeutic effect of anisodamine in disseminated intravascular coagulation: Study of platelet adhesion and aggregation, malondialdehyde, thromboxane B2, 6-keto- prostaglandin F1 alpha, and microcirculation. Exp. Hematol. 15(1): 65-71, 1987.
36. Zhang, Z.M. and J.Y. Wang. Inhibitory effects of Anisodamine on store-operated calcium currents induced by oxygen free radical in human hepatocyte line HL-7702. J. Gastrointest. Surg. 9(4): 601-603, 2005.
37. Zhou, D.X., Q. Zhong, Z. Li and P.Z. Deng. The protective effects of anisodamine on brain mitochondria damage after complete cerebral ischemia and reperfusion in rabbit. Chin. J. Emerg. Med. 12(3): 176-178, 2003.