메뉴 건너뛰기




Volumn 29, Issue 8, 2011, Pages 1035-1040

In vivo measurement of normal rat intracellular pyruvate and lactate levels after injection of hyperpolarized [1- 13C]alanine

Author keywords

Dynamic nuclear polarization (DNP); Hyperpolarized carbon 13; Magnetic resonance spectroscopy spectroscopic imaging; Monocarboxylate transporter (MCT)

Indexed keywords

ALANINE; CARBON 13; LACTIC ACID; PYRUVIC ACID;

EID: 80052615675     PISSN: 0730725X     EISSN: 18735894     Source Type: Journal    
DOI: 10.1016/j.mri.2011.07.001     Document Type: Article
Times cited : (37)

References (13)
  • 2
    • 33845292936 scopus 로고    scopus 로고
    • Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis
    • Golman K., Zandt R.I., Lerche M., Pehrson R., Ardenkjaer-Larsen J.H. Metabolic imaging by hyperpolarized 13C magnetic resonance imaging for in vivo tumor diagnosis. Cancer Res 2006, 66:10855-10860.
    • (2006) Cancer Res , vol.66 , pp. 10855-10860
    • Golman, K.1    Zandt, R.I.2    Lerche, M.3    Pehrson, R.4    Ardenkjaer-Larsen, J.H.5
  • 3
    • 35948970970 scopus 로고    scopus 로고
    • Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy
    • Day S.E., Kettunen M.I., Gallagher F.A., Hu D.E., Lerche M., Wolber J., et al. Detecting tumor response to treatment using hyperpolarized 13C magnetic resonance imaging and spectroscopy. Nat Med 2007, 13:1382-1387.
    • (2007) Nat Med , vol.13 , pp. 1382-1387
    • Day, S.E.1    Kettunen, M.I.2    Gallagher, F.A.3    Hu, D.E.4    Lerche, M.5    Wolber, J.6
  • 4
    • 54249093810 scopus 로고    scopus 로고
    • Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading
    • Albers M.J., Bok R., Chen A.P., Cunningham C.H., Zierhut M.L., Zhang V., et al. Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading. Cancer Res 2008, 68:8607-8615.
    • (2008) Cancer Res , vol.68 , pp. 8607-8615
    • Albers, M.J.1    Bok, R.2    Chen, A.P.3    Cunningham, C.H.4    Zierhut, M.L.5    Zhang, V.6
  • 6
    • 0021089931 scopus 로고
    • Natural abundance carbon-13 nuclear magnetic resonance spectroscopy of liver and adipose tissue of the living rat
    • Canioni P., Alger J.R., Shulman R.G. Natural abundance carbon-13 nuclear magnetic resonance spectroscopy of liver and adipose tissue of the living rat. Biochem 1983, 22:4974-4980.
    • (1983) Biochem , vol.22 , pp. 4974-4980
    • Canioni, P.1    Alger, J.R.2    Shulman, R.G.3
  • 7
    • 79951507755 scopus 로고    scopus 로고
    • Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research
    • Kurhanewicz J., Vigneron D.B., Brindle K., Chekmenev E.Y., Comment A., Cunningham C.H., et al. Analysis of cancer metabolism by imaging hyperpolarized nuclei: prospects for translation to clinical research. Neoplasia 2011, 13:81-97.
    • (2011) Neoplasia , vol.13 , pp. 81-97
    • Kurhanewicz, J.1    Vigneron, D.B.2    Brindle, K.3    Chekmenev, E.Y.4    Comment, A.5    Cunningham, C.H.6
  • 8
    • 70849085768 scopus 로고    scopus 로고
    • Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells
    • Harris T., Eliyahu G., Frydman L., Degani H. Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells. Proc Natl Acad Sci U S A 2009, 106:18131-18136.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 18131-18136
    • Harris, T.1    Eliyahu, G.2    Frydman, L.3    Degani, H.4
  • 9
    • 0025095302 scopus 로고
    • Role of amino acid transport and countertransport in nutrition and metabolism
    • Christensen H.N. Role of amino acid transport and countertransport in nutrition and metabolism. Physiol Rev 1990, 70:43-77.
    • (1990) Physiol Rev , vol.70 , pp. 43-77
    • Christensen, H.N.1
  • 10
    • 0015578098 scopus 로고
    • The glucose-alanine cycle
    • Felig P. The glucose-alanine cycle. Metabolism 1973, 22:179-207.
    • (1973) Metabolism , vol.22 , pp. 179-207
    • Felig, P.1
  • 11
    • 70350287827 scopus 로고    scopus 로고
    • In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate
    • Hu S., Chen A.P., Zierhut M.L., Bok R., Yen Y., Schroeder M.A., et al. In vivo carbon-13 dynamic MRS and MRSI of normal and fasted rat liver with hyperpolarized 13C-pyruvate. Mol Imaging Biol 2009, 11:399-407.
    • (2009) Mol Imaging Biol , vol.11 , pp. 399-407
    • Hu, S.1    Chen, A.P.2    Zierhut, M.L.3    Bok, R.4    Yen, Y.5    Schroeder, M.A.6
  • 12
    • 75749094342 scopus 로고    scopus 로고
    • 3D Compressed sensing for highly accelerated hyperpolarized 13C MRSI with in vivo applications to transgenic mouse models of cancer
    • Hu S., Lustig M., Balakrishnan A., Larson P.E.Z., Bok R., Kurhanewicz J., et al. 3D Compressed sensing for highly accelerated hyperpolarized 13C MRSI with in vivo applications to transgenic mouse models of cancer. Magn Reson Med 2010, 63:312-321.
    • (2010) Magn Reson Med , vol.63 , pp. 312-321
    • Hu, S.1    Lustig, M.2    Balakrishnan, A.3    Larson, P.E.Z.4    Bok, R.5    Kurhanewicz, J.6
  • 13
    • 79960006190 scopus 로고    scopus 로고
    • 13C-Pyruvate imaging reveals alterations in glycolysis that precede tumor formation and regression
    • Hu S., Balakrishnan A., Bok R.A., Anderton B., Larson P.E.Z., Nelson S.J., et al. 13C-Pyruvate imaging reveals alterations in glycolysis that precede tumor formation and regression. Cell Metab 2011, 14:131-142.
    • (2011) Cell Metab , vol.14 , pp. 131-142
    • Hu, S.1    Balakrishnan, A.2    Bok, R.A.3    Anderton, B.4    Larson, P.E.Z.5    Nelson, S.J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.