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Volumn 71, Issue 13, 2011, Pages 1721-1732

Pirfenidone: In idiopathic pulmonary fibrosis

Author keywords

Adis Drug Profiles; Idiopathic pulmonary fibrosis; Pirfenidone

Indexed keywords

AMIODARONE; CHLORAMPHENICOL; CIGARETTE SMOKE; CIPROFLOXACIN; CYTOCHROME P450 1A2; FLUCONAZOLE; FLUOXETINE; FLUVOXAMINE; LIVER ENZYME; OMEPRAZOLE; PAROXETINE; PIRFENIDONE; PROPAFENONE;

EID: 80052613002     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/11207710-000000000-00000     Document Type: Article
Times cited : (77)

References (38)
  • 1
    • 79952717349 scopus 로고    scopus 로고
    • An official ATS/ERS/JRS/ALAT statement: Idiopathic pulmonary fibrosis: Evidence-based guidelines for diagnosis and management
    • Mar 15
    • Raghu G, Collard HR, Egan JJ, et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am J Respir Crit Care Med 2011 Mar 15; 183 (6): 788-824
    • (2011) Am J Respir Crit Care Med , vol.183 , Issue.6 , pp. 788-824
    • Raghu, G.1    Collard, H.R.2    Egan, J.J.3
  • 2
    • 77958475711 scopus 로고    scopus 로고
    • Current and future treatment options in idiopathic pulmonary fibrosis
    • Jul 1
    • Hauber H-P, Blaukovitsch M. Current and future treatment options in idiopathic pulmonary fibrosis. Inflamm Allergy Drug Targets 2010 Jul 1; 9 (3): 158-72
    • (2010) Inflamm Allergy Drug Targets , vol.9 , Issue.3 , pp. 158-172
    • Hauber, H.-P.1    Blaukovitsch, M.2
  • 4
    • 79956356774 scopus 로고    scopus 로고
    • Pirfenidone for idiopathic pulmonary fibrosis [letter]
    • May 21
    • Bouros D. Pirfenidone for idiopathic pulmonary fibrosis [letter]. Lancet 2011 May 21; 377 (9779): 1727-9
    • (2011) Lancet , vol.377 , Issue.9779 , pp. 1727-1729
    • Bouros, D.1
  • 5
    • 84857140266 scopus 로고    scopus 로고
    • InPharm [Accessed 2011 Jul 12]
    • InPharm. First idiopathic pulmonary fibrosis drug approved [online]. Available from URL: http://www. inpharm.com/news/149931/intermune-idiopathic- pulmonaryfibrosis-esbriet-pirfenidone [Accessed 2011 Jul 12]
    • First Idiopathic Pulmonary Fibrosis Drug Approved [Online]
  • 7
    • 80052615769 scopus 로고    scopus 로고
    • Development and utility of pirfenidone in the treatment of idiopathic pulmonary fibrosis: Review of preclinical science and recent clinical trials
    • Jackson RM, Gomez-Marin O. Development and utility of pirfenidone in the treatment of idiopathic pulmonary fibrosis: review of preclinical science and recent clinical trials. Transpl Res Risk Manag 2011; 3: 55-63
    • (2011) Transpl Res Risk Manag , vol.3 , pp. 55-63
    • Jackson, R.M.1    Gomez-Marin, O.2
  • 8
    • 48149113955 scopus 로고    scopus 로고
    • Antifibrotic action of pirfenidone and prednisolone: Different effects on pulmonary cytokines and growth factors in bleomycininduced murine pulmonary fibrosis
    • Aug 20
    • Oku H, Shimizu T, Kawabata T, et al. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycininduced murine pulmonary fibrosis. Eur J Pharmacol 2008 Aug 20; 590 (1-3): 400-8
    • (2008) Eur J Pharmacol , vol.590 , Issue.1-3 , pp. 400-408
    • Oku, H.1    Shimizu, T.2    Kawabata, T.3
  • 9
    • 0032842405 scopus 로고    scopus 로고
    • Effects of pirfenidone on transforming growth factor-β gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis
    • Iyer SN, Gurujeyalakshmi G, Giri SN. Effects of pirfenidone on transforming growth factor-b gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis. J Pharmacol Exp Ther 1999 Oct; 291 (1): 367-73 (Pubitemid 29451612)
    • (1999) Journal of Pharmacology and Experimental Therapeutics , vol.291 , Issue.1 , pp. 367-373
    • Iyer, S.N.1    Gurujeyalakshmi, G.2    Giri, S.N.3
  • 10
    • 84857140367 scopus 로고    scopus 로고
    • European Medicines Agency [Accessed 2011 May 1]
    • European Medicines Agency. Esbriet: CHMP assessment report (EMA/CHMP/115147/2011) [online]. Available from URL: http://www.ema.europa.eu/ docs/en-GB/documentlibrary/EPAR-Public-assessmentreport/human/002154/ WC500103073.pdf [Accessed 2011 May 1]
    • Esbriet: CHMP Assessment Report (EMA/CHMP/115147/2011) [Online]
  • 12
    • 0032917960 scopus 로고    scopus 로고
    • Effects of pirfenidone on procollagen gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis
    • Iyer SN, Gurujeyalakshmi G, Giri SN. Effects of pirfenidone on procollagen gene expression at the transcriptional level in bleomycin hamster model of lung fibrosis. J Pharmacol Exp Ther 1999 Apr; 289 (1): 211-8 (Pubitemid 29156031)
    • (1999) Journal of Pharmacology and Experimental Therapeutics , vol.289 , Issue.1 , pp. 211-218
    • Iyer, S.N.1    Gurujeyalakshmi, G.2    Giri, S.N.3
  • 13
    • 0029318974 scopus 로고
    • Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters
    • Iyer SN, Wild JS, Schiedt MJ, et al. Dietary intake of pirfenidone ameliorates bleomycin-induced lung fibrosis in hamsters. J Labs Clin Med 1995; 125: 779-85
    • (1995) J Labs Clin Med , vol.125 , pp. 779-785
    • Iyer, S.N.1    Wild, J.S.2    Schiedt, M.J.3
  • 14
    • 79958297487 scopus 로고    scopus 로고
    • Antifibrotic activities of pirfenidone in animal models
    • Jun 1
    • Schaefer CJ, Ruhrmund DW, Pan L, et al. Antifibrotic activities of pirfenidone in animal models. Eur Respir Rev 2011 Jun 1; 20 (120): 85-97
    • (2011) Eur Respir Rev , vol.20 , Issue.120 , pp. 85-97
    • Schaefer, C.J.1    Ruhrmund, D.W.2    Pan, L.3
  • 16
    • 0033923129 scopus 로고    scopus 로고
    • Anti-inflammatory effect of pirfenidone in the bleomycin- hamster model of lung inflammation
    • DOI 10.1023/A:1007068313370
    • Iyer SN, Hyde DM, Giri SN. Anti-inflammatory effect of pirfenidone in the bleomycin-hamster model of lung inflammation. Inflammation 2000 Oct; 24 (5): 477-91 (Pubitemid 30452555)
    • (2000) Inflammation , vol.24 , Issue.5 , pp. 477-491
    • Iyer, S.N.1    Hyde, D.M.2    Giri, S.N.3
  • 18
    • 0037141772 scopus 로고    scopus 로고
    • Pirfenidone suppresses tumor necrosis factor-α, enhances interleukin-10 and protects mice from endotoxic shock
    • DOI 10.1016/S0014-2999(02)01757-0, PII S0014299902017570
    • Oku H, Nakazato H, Horikawa T, et al. Pirfenidone suppresses tumor necrosis factor-a, enhances interleukin-10 and protects mice from endotoxic shock. Eur J Pharmacol 2002 Jun 20; 446 (1-3): 167-76 (Pubitemid 34722571)
    • (2002) European Journal of Pharmacology , vol.446 , Issue.1-3 , pp. 167-176
    • Oku, H.1    Nakazato, H.2    Horikawa, T.3    Tsuruta, Y.4    Suzuki, R.5
  • 19
    • 0037141774 scopus 로고    scopus 로고
    • A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-α at the translational level
    • DOI 10.1016/S0014-2999(02)01758-2, PII S0014299902017582
    • Nakazato H, Oku H, Yamane S, et al. A novel anti-fibrotic agent pirfenidone suppresses tumor necrosis factor-a at the translational level. Eur J Pharmacol 2002 Jun 20; 446 (1-3): 177-85 (Pubitemid 34722572)
    • (2002) European Journal of Pharmacology , vol.446 , Issue.1-3 , pp. 177-185
    • Nakazato, H.1    Oku, H.2    Yamane, S.3    Tsuruta, Y.4    Suzuki, R.5
  • 20
    • 80052613721 scopus 로고    scopus 로고
    • Pirfenidone attenuates the release of neutrophil (NCA) and monocyte chemotactic activity (MCA) from human lung fibroblasts (FLH-1) in response to tumor necrosis factor (TNF)-alpha [abstract]
    • May 1
    • Koyama S, Kamijyo S, Hashizume M, et al. Pirfenidone attenuates the release of neutrophil (NCA) and monocyte chemotactic activity (MCA) from human lung fibroblasts (FLH-1) in response to tumor necrosis factor (TNF)-alpha [abstract]. Am J Respir Crit Care Med 2010 May 1; 181 Suppl.: A3529
    • (2010) Am J Respir Crit Care Med , vol.181 , Issue.SUPPL.
    • Koyama, S.1    Kamijyo, S.2    Hashizume, M.3
  • 21
    • 0034004098 scopus 로고    scopus 로고
    • Pirfenidone inhibits NADPH-dependent microsomal lipid peroxidation and scavenges hydroxyl radicals
    • Misra H, Rabideau C. Pirfenidone inhibits NADPHdependent microsomal lipid peroxidation and scavenges hydroxyl radicals. Molec Cell Biochem 2000 Jan; 204 (1-2): 119-26 (Pubitemid 30111765)
    • (2000) Molecular and Cellular Biochemistry , vol.204 , Issue.1-2 , pp. 119-126
    • Misra, H.P.1    Rabideau, C.2
  • 22
    • 0032704292 scopus 로고    scopus 로고
    • Effects of pirfenidone on the generation of reactive oxygen species in vitro
    • Giri SN, Leonard S, Shi X, et al. Effects of pirfenidone on the generation of reactive oxygen species in vitro . J Environ Pathol Toxicol Oncol 1999; 18 (3): 169-77
    • (1999) J Environ Pathol Toxicol Oncol , vol.18 , Issue.3 , pp. 169-177
    • Giri, S.N.1    Leonard, S.2    Shi, X.3
  • 25
    • 34648816354 scopus 로고    scopus 로고
    • Single- and multiple-dose pharmacokinetics of pirfenidone, an antifibrotic agent, in healthy Chinese volunteers
    • DOI 10.1177/0091270007304104
    • Shi S, Wu J, Chen H, et al. Single-and multiple-dose pharmacokinetics of pirfenidone, an antifibrotic agent, in healthy Chinese volunteers. J Clin Pharmacol 2007 Oct; 47 (10): 1268-76 (Pubitemid 47459661)
    • (2007) Journal of Clinical Pharmacology , vol.47 , Issue.10 , pp. 1268-1276
    • Shi, S.1    Wu, J.2    Chen, H.3    Chen, H.4    Wu, J.5    Zeng, F.6
  • 26
    • 67349131293 scopus 로고    scopus 로고
    • Effect of food and antacids on the pharmacokinetics of pirfenidone in older healthy adults
    • Aug
    • Rubino CM, Bhavnani SM, Ambrose PG, et al. Effect of food and antacids on the pharmacokinetics of pirfenidone in older healthy adults. Pulm Pharmacol Ther 2009 Aug; 22 (4): 279-85
    • (2009) Pulm Pharmacol Ther , vol.22 , Issue.4 , pp. 279-285
    • Rubino, C.M.1    Bhavnani, S.M.2    Ambrose, P.G.3
  • 27
    • 84857141737 scopus 로고    scopus 로고
    • InterMune [Accessed 2011 May 11]
    • InterMune. Esbriet(pirfenidone): EU summary of product characteristics [online]. Available from URL: http://www. ema.europa.eu/docs/en-GB/ documentlibrary/EPAR-ProductInformation/human/002154/WC500103049.pdf [Accessed 2011 May 11]
    • Esbriet(pirfenidone): EU Summary of Product Characteristics [Online]
  • 28
    • 0032926937 scopus 로고    scopus 로고
    • Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: Results of a prospective, open-label phase II study
    • Raghu G, Johnson WC, Lockhart D, et al. Treatment of idiopathic pulmonary fibrosis with a new antifibrotic agent, pirfenidone: results of a prospective, open-label phase II study. Am J Respir Crit Care Med 1999 Apr 1; 159 (4): 1061-9 (Pubitemid 29202536)
    • (1999) American Journal of Respiratory and Critical Care Medicine , vol.159 , Issue.I4 , pp. 1061-1069
    • Raghu, G.1    Johnson, W.C.2    Lockhart, D.3    Mageto, Y.4
  • 29
    • 0036967820 scopus 로고    scopus 로고
    • Open-label compassionate use one year-treatment with pirfenidone to patients with chronic pulmonary fibrosis
    • Nagai S, Hamada K, Shigematsu M, et al. Open-label compassionate use one year-treatment with pirfenidone to patients with chronic pulmonary fibrosis. Intern Med 2002 Dec; 41 (12): 1118-23 (Pubitemid 36150010)
    • (2002) Internal Medicine , vol.41 , Issue.12 , pp. 1118-1123
    • Nagai, S.1    Hamada, K.2    Shigematsu, M.3    Taniyama, M.4    Yamauchi, S.5    Izumi, T.6
  • 31
    • 79956341531 scopus 로고    scopus 로고
    • Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): Two randomised trials
    • Noble PW, et al. Pirfenidone in patients with idiopathic pulmonary fibrosis (CAPACITY): two randomised trials. Lancet 2011; 377 (9779): 1760-9
    • (2011) Lancet , vol.377 , Issue.9779 , pp. 1760-1769
    • Noble, P.W.1
  • 32
    • 77951160564 scopus 로고    scopus 로고
    • Pirfenidone in idiopathic pulmonary fibrosis
    • Apr
    • Taniguchi H, Ebina M, Kondoh Y, et al. Pirfenidone in idiopathic pulmonary fibrosis. Eur Respir J 2010 Apr; 35 (4): 821-9
    • (2010) Eur Respir J , vol.35 , Issue.4 , pp. 821-829
    • Taniguchi, H.1    Ebina, M.2    Kondoh, Y.3
  • 33
    • 80052625979 scopus 로고    scopus 로고
    • Pirfenidone doseresponse in patients with idiopathic pulmonary fibrosis (IPF): A comprehensive analysis of outcomes in CAPACITY 2 [abstract no. 388]
    • Sep 18-22; Barcelona
    • Costabel U, Albera C, Bradford W, et al. Pirfenidone doseresponse in patients with idiopathic pulmonary fibrosis (IPF): a comprehensive analysis of outcomes in CAPACITY 2 [abstract no. 388]. 20th Annual Congress of the European Respiratory Society; 2010 Sep 18-22; Barcelona
    • (2010) 20th Annual Congress of the European Respiratory Society
    • Costabel, U.1    Albera, C.2    Bradford, W.3
  • 34
    • 80052629334 scopus 로고    scopus 로고
    • The effect of treatment with pirfenidone on death or lung transplantation in patients with idiopathic pulmonary fibrosis (IPF): Analysis of outcomes in the CAPACITY (CAP) trials [abstract no. 391]
    • Sep 18-22; Barcelona
    • Valeyre D, Albera C, Bradford W, et al. The effect of treatment with pirfenidone on death or lung transplantation in patients with idiopathic pulmonary fibrosis (IPF): analysis of outcomes in the CAPACITY (CAP) trials [abstract no. 391]. 20th Annual Congress of the European Respiratory Society; 2010 Sep 18-22; Barcelona
    • (2010) 20th Annual Congress of the European Respiratory Society
    • Valeyre, D.1    Albera, C.2    Bradford, W.3
  • 35
    • 79951844263 scopus 로고    scopus 로고
    • Clinical course and prediction of survival in idiopathic pulmonary fibrosis
    • Feb
    • Ley B, Collard HR, King TE. Clinical course and prediction of survival in idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 2011 Feb; 183 (4): 431-40
    • (2011) Am J Respir Crit Care Med , vol.183 , Issue.4 , pp. 431-440
    • Ley, B.1    Collard, H.R.2    King, T.E.3
  • 36
    • 80052627476 scopus 로고    scopus 로고
    • The magnitude of pirfenidone treatment effect in patients with idiopathic pulmonary fibrosis (IPF): A pooled analysis of outcomes in the CAPACITY (CAP) studies [abstract no. 389]
    • Sep 18-22; Barcelona
    • Albera C, Bradford W, Costabel U, et al. The magnitude of pirfenidone treatment effect in patients with idiopathic pulmonary fibrosis (IPF): a pooled analysis of outcomes in the CAPACITY (CAP) studies [abstract no. 389]. 20th Annual Congress of the European Respiratory Society; 2010 Sep 18-22; Barcelona
    • (2010) 20th Annual Congress of the European Respiratory Society
    • Albera, C.1    Bradford, W.2    Costabel, U.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.