Synthesis and Antileukemic Activity of Novel 4-(3-(Piperidin-4-yl) Propyl)Piperidine Derivatives

Chemical Biology and Drug Design

Volumn 78, Issue 4, 2011, Pages 622-630

  Vinaya, Kambappa ^a,b   Kavitha, Chandagirikoppal V ^c,d   Chandrappa, Siddappa ^a   Prasanna, Doddakunche S ^a   Raghavan, Sathees C ^c   Rangappa, Kanchugarakoppal S ^a  

^a UNIVERSITY OF MYSORE   (India)

^b Government First Grade College   (India)

^c INDIAN INSTITUTE OF SCIENCE   (India)

^d Government College for Women   (India)

Author keywords

4 amino benzoic acid; Anticancer agents; Apoptosis; Cell death; DNA damage; Leukemia

Indexed keywords

(2 AMINO 1,2,3,4 TETRAHYDRONAPHTHALEN 2 YL) [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]METHANONE; (4 AMINOPHENYL) [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]METHANONE; (4 FLUORO 3 NITROPHENYL) [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]METHANONE; (6 FLUORO 3,4 DIHYDRO 2H CHROMEN 2 YL) [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]METHANONE; 2 [5 [[5 (4 CHLOROPHENYL)FURAN 2 YL]METHYLENE] 4 OXO 2 THIOXOTHIAZOLIDIN 3 YL]ACETIC ACID DERIVATIVE; 2 AMINO 3 (2' ETHYL 4' METHOXYBIPHENYL 4 YL) 1 [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]PROPAN 1 ONE; 3 [2 OXO 2 [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]ETHYL] 2 THIOXOTHIAZOLIDIN 4 ONE; 4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDINE DERIVATIVE; 5 [[5 (4 CHLOROPHENYL)FURAN 2 YL]METHYLENE] 3 [2 OXO 2 [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]ETHYL] 2 THIOXOTHIAZOLIDIN 4 ONE; 6 BROMO 3 [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDINE 1 CARBONYL] 2H CHROMEN 2 ONE; [3 (CYCLOPENTYLOXY) 4 METHOXYPHENYL] [4 [3 (PIPERIDIN 4 YL)PROPYL]PIPERIDIN 1 YL]METHANONE; ACETIC ACID DERIVATIVE; AMIDE; ANTILEUKEMIC AGENT; LACTATE DEHYDROGENASE; PHENYL GROUP; PIPERIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE; CELL PROLIFERATION; CROSS COUPLING REACTION; DNA FRAGMENTATION; DNA STRAND BREAKAGE; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFRARED SPECTROMETRY; LEUKEMIA; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; DNA FRAGMENTATION; HUMANS; LEUKEMIA; MAGNETIC RESONANCE SPECTROSCOPY; PIPERIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 80052608058     PISSN: 17470277     EISSN: 17470285     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2011.01184.x     Document Type: Article

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