Plasma leptin levels and risk of breast cancer in premenopausal women

Cancer Prevention Research

Volumn 4, Issue 9, 2011, Pages 1449-1456

  Harris, Holly R ^a,b   Tworoger, Shelley S ^a,b   Hankinson, Susan E ^a,b   Rosner, Bernard A ^a   Michels, Karin B ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTRADIOL; LEPTIN; LEPTIN RECEPTOR;

ADULT; ARTICLE; BODY FAT; BODY MASS; BREAST CANCER; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HORMONE BLOOD LEVEL; HUMAN; INCIDENTAL FINDING; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; PREMENOPAUSE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR;

ADULT; BODY MASS INDEX; BREAST NEOPLASMS; CASE-CONTROL STUDIES; COHORT STUDIES; FEMALE; HUMANS; LEPTIN; MIDDLE AGED; PREMENOPAUSE; PROSPECTIVE STUDIES; RECEPTORS, LEPTIN; REGRESSION ANALYSIS; RISK; RISK FACTORS;

EID: 80052600134     PISSN: 19406207     EISSN: 19406215     Source Type: Journal    
DOI: 10.1158/1940-6207.CAPR-11-0125     Document Type: Article

References (51)

1. Food, nutrition, physical activity, and the prevention of cancer: a global perspective. London, UK: World Cancer Research Fund/American Institute for Cancer Research; 2007. p. 289.
2. Key T., Pike M. The role of oestrogens and progestagens in the epidemiology and prevention of breast cancer. Eur J Cancer Clin Oncol 1988;24:29-43. (Pubitemid 18009332)
3. Key T., Appleby P., Reeves G., Roddam A., Dorgan J., Longcope C., et al. Body mass index, serum sex hormones, and breast cancer risk in postmenopausal women. J Natl Cancer Inst 2003;95:1218-1226 (Pubitemid 37069552)
4. Michels K.B., Terry K.L., Willett W.C. Longitudinal study on the role of body size in premenopausal breast cancer. Arch Intern Med 2006; 166:2395-2402 (Pubitemid 44833368)
5. Weiderpass E., Braaten T., Magnusson C., Kumle M., Vainio H., Lund E., et al. A prospective study of body size in different periods of life and risk of premenopausal breast cancer. Cancer Epidemiol Biomarkers Prev 2004;13:1121-1127 (Pubitemid 38917900)
6. Palmer J.R., Adams-Campbell L.L., Boggs D.A., Wise L.A., Rosenberg L. A prospective study of body size and breast cancer in black women. Cancer Epidemiol Biomarkers Prev 2007;16:1795-1802 (Pubitemid 47450509)
7. Tworoger S.S., Eliassen A.H., Missmer S.A., Baer H., Rich-Edwards J., Michels K.B., et al. Birthweight and body size throughout life in relation to sex hormones and prolactin concentrations in premenopausal women. Cancer Epidemiol Biomarkers Prev 2006;15:2494-2501 (Pubitemid 46048311)
8. Potischman N., Swanson C.A., Siiteri P., Hoover R.N. Reversal of relation between body mass and endogenous estrogen concentrations with menopausal status. J Natl Cancer Inst 1996;88:756-758 (Pubitemid 26195024)
9. Considine R.V., Sinha M.K., Heiman M.L., Kriauciunas A., Stephens T.W., Nyce M.R., et al. Serum immunoreactive-leptin concentrations in normal-weight and obese humans. N Engl J Med 1996;334:292-295 (Pubitemid 26033933)
10. Hu X., Juneja S.C., Maihle N.J., Cleary M.P. Leptin-a growth factor in normal and malignant breast cells and for normal mammary gland development. J Natl Cancer Inst 2002;94:1704-1711 (Pubitemid 35446839)
11. Widmaier E., Raff H., KT S. Regulation of organic metabolism and energy balance. In: Vander's human physiology: the mechanisms of body function. 10th ed. New York: McGraw-Hill; 2006 pp. 637-639
12. Ahima R.S., Flier J.S. Adipose tissue as an endocrine organ. Trends Endocrinol Metab 2000;11:327-332
13. Garofalo C., Koda M., Cascio S., Sulkowska M., Kanczuga-Koda L., Golaszewska J., et al. Increased expression of leptin and the leptin receptor as a marker of breast cancer progression: Possible role of obesity-related stimuli. Clin Cancer Res 2006;12:1447-1453
14. Ishikawa M., Kitayama J., Nagawa H. Enhanced expression of leptin and leptin receptor (OB-R) in human breast cancer. Clin Cancer Res 2004;10:4325-4331 (Pubitemid 38878870)
15. O'Brien S.N., Welter B.H., Price T.M. Presence of leptin in breast cell lines and breast tumors. Biochem Biophys Res Commun 1999;259:695-698 (Pubitemid 29335596)
16. Laud K., Gourdou I., Pessemesse L., Peyrat J.P., Djiane J. Identification of leptin receptors in human breast cancer: Functional activity in the T47-D breast cancer cell line. Mol Cell Endocrinol 2002;188:219-226 (Pubitemid 34242679)
17. Sulkowska M., Golaszewska J., Wincewicz A., Koda M., Baltaziak M., Sulkowski S. Leptin-from regulation of fat metabolism to stimulation of breast growth. Pathol Oncol Res 2006;12:69-72. (Pubitemid 44197171)
18. Casabiell X., Pineiro V., Peino R., Lage M., Camina J., Gallego R., et al. Gender differences in both spontaneous and stimulated leptin secretion by human omental adipose tissue in vitro: Dexamethasone and estradiol stimulate leptin release in women, but not in men. J Clin Endocrinol Metab 1998;83:2149-2155 (Pubitemid 28496352)
19. Shimizu H., Shimomura Y., Nakanishi Y., Futawatari T., Ohtani K., Sato N., et al. Estrogen increases in vivo leptin production in rats and human subjects. J Endocrinol 1997;154:285-292 (Pubitemid 27330641)
20. Kitawaki J., Kusuki I., Koshiba H., Tsukamoto K., Honjo H. Leptin directly stimulates aromatase activity in human luteinized granulosa cells. Mol Hum Reprod 1999;5:708-713 (Pubitemid 29366866)
21. Magoffin D., Weitsman S., Aagarawal S., Jakimiuk A. Leptin regulation of aromatase activity in adipose stromal cells from regularly cycling women. Ginekol Pol 1999;70:1-7.
22. Brannian J.D., Hansen K.A. Leptin and ovarian folliculogenesis: Implications for ovulation induction and ART outcomes. Semin Reprod Med 2002;20:103-112 (Pubitemid 34764274)
23. Falk R., Brinton L., Madigan M., Potischman N., Sturgeon S., Malone K., et al. Interrelationships between serum leptin, IGF-1, IGFBP3, Cpeptide and prolactin and breast cancer risk in young women. Breast Cancer Res Treat 2006;98:157-165 (Pubitemid 44050764)
24. Aliustaoglu M., Bilici A., Gumus M., Colak A., Baloglu G., Irmak R., et al. Preoperative serum leptin levels in patients with breast cancer. Med Oncol 2010;27:388-391
25. Coskun U., Gunel N., Toruner F., Sancak B., Onuk E., Bayram O., et al. Serum leptin, prolactin and vascular endothelial growth factor (VEGF) levels in patients with breast cancer. Neoplasma 2003;50:41-46 (Pubitemid 36458939)
26. Hou W., Xu Y., Yu T., Zhang L., Zhang W., Fu C., et al. Adipocytokines and breast cancer risk. Chin Med J 2007;120:1592-1596 (Pubitemid 47595751)
27. Liu C., Chang Y., Cheng S., Chern S., Yang T., Lee J., et al. The roles of serum leptin concentration and polymorphism in leptin receptor gene at codon 109 in breast cancer. Oncology 2007;72:75-81. (Pubitemid 350249133)
28. Mantzoros C.S., Bolhke K., Moschos S., Cramer D.W. Leptin in relation to carcinoma in situ of the breast: A study of pre-menopausal cases and controls. Int J Cancer 1999;80:523-526 (Pubitemid 29047515)
29. Petridou E., Papadiamantis Y., Markopoulos C., Spanos E., Dessypris N., Trichopoulos D. Leptin and insulin growth factor I in relation to breast cancer (Greece). Cancer Causes Control 2000;11:383-388 (Pubitemid 30345235)
30. Sauter E.R., Garofalo C., Hewett J., Hewett J.E., Morelli C., Surmacz E. Leptin expression in breast nipple aspirate fluid (NAF) and serum is influenced by body mass index (BMI) but not by the presence of breast cancer. Horm Metab Res 2004;36:336-340 (Pubitemid 38703795)
31. Tessitore L., Vizio B., Pesola D., Cecchini F., Mussa A., Argiles J., et al. Adipocyte expression and circulating levels of leptin increase in both gynaecological and breast cancer patients. Int J Oncol 2004;24: 1529-1535
32. Woo H-Y, Park H., Ki C-S, Park Y.L., Bae W.G. Relationships among serum leptin, leptin receptor gene polymorphisms, and breast cancer in Korea. Cancer Lett 2006;237:137-142
33. Wu M.H., Chou Y.C., Chou W.Y., Hsu G.C., Chu C.H., Yu C.P., et al. Circulating levels of leptin, adiposity and breast cancer risk. Br J Cancer 2009;100:578-582
34. Stattin P., Söderberg S., Olsson T., Hallmans G., Lenner P., Biessy C., et al. Plasma leptin and breast cancer risk: A prospective study in northern Sweden. Breast Cancer Res Treat 2004;86:191-196 (Pubitemid 39070961)
35. Tworoger S.S., Sluss P., Hankinson S.E. Association between plasma prolactin concentrations and risk of breast cancer among predominately premenopausal women. Cancer Res 2006;66:2476-2482
36. Garland M., Hunter D.J., Colditz G.A., Manson J.E., Stampfer M.J., Spiegelman D., et al. Menstrual cycle characteristics and history of ovulatory infertility in relation to breast cancer risk in a large cohort of US women. Am J Epidemiol 1998;147:636-643 (Pubitemid 28180306)
37. Quantikine: human leptin immunoassay. Minneapolis, MN: R&D Systems.
38. Rosner B. Percentage points for a generalized ESD many-outlier procedure. Technometrics 1983;25:165.
39. Hankinson S., Willett W., Manson J., Colditz G., Hunter D., Spiegelman D., et al. Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 1998;90:1292-1299 (Pubitemid 28433474)
40. Willett W., Stampfer M.J. Total energy intake: Implications for epidemiologic analyses. Am J Epidemiol 1986;124:17-27. (Pubitemid 16095831)
41. Okumura M., Yamamoto M., Sakuma H., Kojima T., Maruyama T., Jamali M., et al. Leptin and high glucose stimulate cell proliferation in MCF-7 human breast cancer cells: Reciprocal involvement of PKC- [alpha] and PPAR expression. Biochim Biophys Acta 2002;1592: 107-116
42. Catalano S., Marsico S., Giordano C., Mauro L., Rizza P., Panno M.L., et al. Leptin enhances, via AP-1, expression of aromatase in the MCF-7 cell line. J Biol Chem 2003;278:28668-28676 (Pubitemid 36935773)
43. Caro J., Sinha M., Kolaczynski J., Zhang P., Considine R. Leptin: The tale of an obesity gene. Diabetes 1996;45:1455-1462 (Pubitemid 26357535)
44. Spiegelman B., Flier J. Adipogenesis and obesity: Rounding out the big picture. Cell 1996;87:377-389 (Pubitemid 26374313)
45. Scarpace P.J., Zhang Y. Leptin resistance: A predisposing factor for diet-induced obesity. Am J Physiol Regul Integr Comp Physiol 2009;296:R493-R500
46. Huang L., Wang Z., Li C. Modulation of circulating leptin levels by its soluble receptor. J Biol Chem 2001;276:6343-6349
47. Sun Q., Van Dam R.M., Meigs J.B., Franco O.H., Mantzoros C.S., Hu F.B. Leptin and soluble leptin receptor levels in plasma and risk of type 2 diabetes in U.S. women. Diabetes 2010;59:611-618
48. Hahn S., Haselhorst U., Quadbeck B., Tan S., Kimmig R., Mann K., et al. Decreased soluble leptin receptor levels in women with polycystic ovary syndrome. Eur J Endocrinol 2006;154:287-294
49. Chu N-F, Spiegelman D., Hotamisligil G.S., Rifai N., Stampfer M., Rimm E.B. Plasma insulin, leptin, and soluble TNF receptors levels in relation to obesity-related atherogenic and thrombogenic cardiovascular disease risk factors among men. Atherosclerosis 2001; 157:495-503. (Pubitemid 32710031)
50. Willett W. Nutritional epidemiology. 2nd ed. Oxford, UK: Oxford University Press; 1998.
51. Troy L., Hunter D., Manson J., Colditz G., Stampfer M., Willett W. The validity of recalled weight among younger women. Int J Obes Relat Metab Disord 1995;19:570-572