Ingestion of (n-3) fatty acids augments basal and platelet activating factor-induced permeability to dextran in the rat mesenteric vascular bed

Journal of Nutrition

Volumn 141, Issue 9, 2011, Pages 1635-1642

  Dombrowsky, Heike ^a,b   Lautenschläger, Ingmar ^a   Zehethofer, Nicole ^b   Lindner, Buko ^b   Schultz, Holger ^b   Uhlig, Stefan ^c   Frerichs, Inéz ^a   Weiler, Norbert ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b RESEARCH CENTER BORSTEL   (Germany)

^c RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARACHIDONIC ACID; CYSTEINE DERIVATIVE; DEXTRAN; ICOSANOID; OMEGA 3 FATTY ACID; PHOSPHOLIPID; PROSTAGLANDIN E2; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE B2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; BLOOD VESSEL PERMEABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEHYDRATION; FAT INTAKE; FEMALE; FLUID TRANSPORT; INFRARED SPECTROSCOPY; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; LIPID COMPOSITION; LYMPH VESSEL; MACROMOLECULE; MEMBRANE FLUIDITY; MESENTERY BLOOD VESSEL; NONHUMAN; PERFUSION PRESSURE; RAT; SMALL INTESTINE; VASOCONSTRICTION; WEIGHT GAIN;

ANIMALS; CAPILLARY PERMEABILITY; DEXTRANS; DIETARY FATS; FATTY ACIDS, OMEGA-3; FEMALE; PHOSPHOLIPIDS; PLATELET ACTIVATING FACTOR; RATS; RATS, WISTAR; SPLANCHNIC CIRCULATION; WEIGHT GAIN;

BACTERIA (MICROORGANISMS); RATTUS;

EID: 80052582600     PISSN: 00223166     EISSN: 15416100     Source Type: Journal    
DOI: 10.3945/jn.111.143016     Document Type: Article

References (51)

1. Leveau P, Wang X, Sun Z, Borjesson A, Andersson E, Andersson R. Severity of pancreatitis-associated gut barrier dysfunction is reduced following treatment with the PAF inhibitor lexipafant. Biochem Pharmacol. 2005;69:1325-31.
2. O'Brien JG, Battistini B, Zaharia F, Plante GE, Sirois P. Effects of tranexamic acid and aprotinin, two antifibrinolytic drugs, on PAF-induced plasma extravasation in unanesthetized rats. Inflammation. 2000;24:411-29.
3. Bar-Natan MF,Wilson MA, Spain DA, Garrison RN. Platelet-activating factor and sepsis-induced small intestinal microvascular hypoperfusion. J Surg Res. 1995;58:38-45.
4. Kubes P, Arfors KE, Granger DN. Platelet-activating factor-induced mucosal dysfunction: role of oxidants and granulocytes. Am J Physiol. 1991;260:G965-71.
5. Rampton DS, Collins CE. Review article: thromboxanes in inflammatory bowel disease: pathogenic and therapeutic implications. Aliment Pharmacol Ther. 1993;7:357-67.
6. Eberhart CE, Dubois RN. Eicosanoids and the gastrointestinal tract. Gastroenterology. 1995;109:285-301.
7. Feigen LP. Differential effects of leukotrienes C4, D4 and E4 in the canine renal and mesenteric vascular beds. J Pharmacol Exp Ther. 1983;225:682-7.
8. Hammarstrom S. Leukotriene C5: a slow reacting substance derived from eicosapentaenoic acid. J Biol Chem. 1980;255:7093-4.
9. Grimminger F, Mayer K, Kramer HJ, Stevens J, Walmrath D, Seeger W. Differential vasoconstrictor potencies of free fatty acids in the lung vasculature: 2-versus 3-series prostanoid generation. J Pharmacol Exp Ther. 1993;267:259-65.
10. Lokesh BR, Hsieh HL, Kinsella JE. Alterations in the lipids and prostaglandins in mouse spleen following the ingestion of menhaden oil. Ann Nutr Metab. 1986;30:357-64.
11. Grimminger F, Mayer K, Kiss L, Walmrath D, Seeger W. PAF-induced synthesis of tetraenoic and pentaenoic leukotrienes in the isolated rabbit lung. Am J Physiol Lung Cell Mol Physiol. 2000;278:L268-75.
12. Roig-Perez S, Guardiola F, Moreto M, Ferrer R. Lipid peroxidation induced by DHA enrichment modifies paracellular permeability in Caco-2 cells: protective role of taurine. J Lipid Res. 2004;45: 1418-28.
13. Usami M, Muraki K, Iwamoto M, Ohata A, Matsushita E, Miki A. Effect of eicosapentaenoic acid (EPA) on tight junction permeability in intestinal monolayer cells. Clin Nutr. 2001;20:351-9.
14. Usami M, Komurasaki T, Hanada A, Kinoshita K, Ohata A. Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation. Nutrition. 2003;19:150-6.
15. James M, Proudman S, Cleland L. Fish oil and rheumatoid arthritis: past, present and future. Proc Nutr Soc. 2010;69:316-23.
16. Seidner DL, Lashner BA, Brzezinski A, Banks PL, Goldblum J, Fiocchi C, Katz J, Lichtenstein GR, Anton PA, Kam LY, et al. An oral supplement enriched with fish oil, soluble fiber, and antioxidants for corticosteroid sparing in ulcerative colitis: a randomized, controlled trial. Clin Gastroenterol Hepatol. 2005;3:358-69.
17. McCall TB, O'Leary D, Bloomfield J, O'Morain CA. Therapeutic potential of fish oil in the treatment of ulcerative colitis. Aliment Pharmacol Ther. 1989;3:415-24.
18. Pontes-Arruda A, Demichele S, Seth A, Singer P. The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. JPEN J Parenter Enteral Nutr. 2008;32:596-605.
19. Marik PE, Zaloga GP. Immunonutrition in critically ill patients: a systematic review and analysis of the literature. Intensive CareMed. 2008;34:1980-90.
20. Friesecke S, Lotze C, Kohler J, Heinrich A, Felix SB, Abel P. Fish oil supplementation in the parenteral nutrition of critically ill medical patients: a randomised controlled trial. Intensive Care Med. 2008;34:1411-20.
21. Barbosa VM, Miles EA, Calhau C, Lafuente E, Calder PC. Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial. Crit Care. 2010;14:R5.
22. Lautenschläger I, Dombrowsky H, Frerichs I, Kuchenbecker SC, Bade S, Schultz H, Zabel P, Scholz J, Weiler N, Uhlig S. A model of the isolated perfused rat small intestine. Am J Physiol Gastrointest Liver Physiol. 2010;298:G304-13.
23. Nicklas W, Baneux P, Boot R, Decelle T, Deeny AA, Fumanelli M, Illgen-Wilcke B. Recommendations for the health monitoring of rodent and rabbit colonies in breeding and experimental units. Lab Anim. 2002;36:20-42.
24. Bligh EG, Dyer WJ. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 1959;37:911-7.
25. Hubner G, Crone C, Lindner B. lipID-a software tool for automated assignment of lipids in mass spectra. J Mass Spectrom. 2009;44: 1676-83.
26. Mantsch HH, McElhaney RN. Phospholipid phase transitions in model and biological membranes as studied by infrared spectroscopy. Chem Phys Lipids. 1991;57:213-26.
27. R Development Core Team. R Foundation for Statistical Computing. R: a language and environment for statistical computing. Vienna; 2011, ISBN 3-900051-07-0. Available from: http://www.R-project.org.
28. Curran-Everett D. Multiple comparisons: philosophies and illustrations. Am J Physiol Regul Integr Comp Physiol. 2000;279:R1-8.
29. Anzueto L, Benoit JN, Granger DN. A rat model for studying the intestinal circulation. Am J Physiol. 1984;246:G56-61.
30. Singer P, Shapiro H, Theilla M, Anbar R, Singer J, Cohen J. Antiinflammatory properties of omega-3 fatty acids in critical illness: novel mechanisms and an integrative perspective. Intensive Care Med. 2008; 34:1580-92.
31. Rees D, Miles EA, Banerjee T, Wells SJ, Roynette CE, Wahle KW, Calder PC. Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: a comparison of young and older men. Am J Clin Nutr. 2006;83:331-42.
32. Palombo JD, Lydon EE, Chen PL, Bistrian BR, Forse RA. Fatty acid composition of lung, macrophage and surfactant phospholipids after short-term enteral feeding with n-3 lipids. Lipids. 1994;29:643-9.
33. Hung P, Gu JY, Kaku S, Yunoki S, Ohkura K, Ikeda I, Tachibana H, Sugano M, Yazawa K, Yamada K. Dietary effects of eicosapentaenoic and docosahexaenoic acid esters on lipid metabolism and immune parameters in Sprague-Dawley rats. Biosci Biotechnol Biochem. 2000; 64:2588-93.
34. Kudo I, Murakami M. Phospholipase A2 enzymes. Prostaglandins Other Lipid Mediat. 2002;68-69:3-58.
35. Murakami M, Shimbara S, Kambe T, Kuwata H, Winstead MV, Tischfield JA, Kudo I. The functions of five distinct mammalian phospholipase A2S in regulating arachidonic acid release. Type IIa and type V secretory phospholipase A2S are functionally redundant and act in concert with cytosolic phospholipase A2. J Biol Chem. 1998;273: 14411-23.
36. Lautenschläger I, Dombrowsky H, Sarau J, Wong YL, Zabel P, Frerichs I, Unlig S, Weiler N. Mechanismen der PAF-induzierten Perfusions-und Permeabilitā tsünderungen om isoliet perfundierten Dūnndarm der Ratte. Anästh Internsivmed. 2010;51:406.
37. Hsueh W, Gonzalez-Crussi F, Arroyave JL. Release of leukotriene C4 by isolated, perfused rat small intestine in response to platelet-activating factor. J Clin Invest. 1986;78:108-14.
38. Northover AM, Northover BJ. Vasoconstriction in rat isolated mesentery and small intestine in response to various activators of protein kinase C. Agents Actions. 1994;43:29-34.
39. Kuebler WM, Yang Y, Samapati R, Uhlig S. Vascular barrier regulation by PAF, ceramide, caveolae, and NO - an intricate signaling network with discrepant effects in the pulmonary and systemic vasculature. Cell Physiol Biochem. 2010;26:29-40.
40. Jean-Baptiste E. Cellular mechanisms in sepsis. J Intensive Care Med. 2007;22:63-72.
41. Poeze M, Froon AH, Ramsay G, Buurman WA, Greve JW. Decreased organ failure in patients with severe SIRS and septic shock treated with the platelet-activating factor antagonist TCV-309: a prospective, multicenter, double-blind, randomized phase II trial. TCV-309 Septic Shock Study Group. Shock. 2000;14:421-8.
42. Mochizuki T, Satsu H, Totsuka M, Shimizu M. Transepithelial transport of macromolecular substances in IL-4 treated human intestinal T84 cell monolayers. Biosci Biotechnol Biochem. 2009;73:2422-6.
43. Suzuki Y, Deitch EA, Mishima S, Duran WN, Xu DZ. Endotoxininduced mesenteric microvascular changes involve iNOS-derived nitric oxide: results from a study using iNOS knock out mice. Shock. 2000; 13:397-403.
44. Hu G, Minshall RD. Regulation of transendothelial permeability by Src kinase. Microvasc Res. 2009;77:21-5.
45. Kiliaan AJ, Scholten G, Bijlsma PB, Dekker K, Groot JA. Influence of forskolin and carbachol on intestinal absorption of horseradish peroxidase in the goldfish (Carassius auratus). Cell Tissue Res. 1996;285: 51-6.
46. Rosella O, Sinclair A, Gibson PR. Polyunsaturated fatty acids reduce non-receptor-mediated transcellular permeation of protein across a model of intestinal epithelium in vitro. J Gastroenterol Hepatol. 2000; 15:626-31.
47. Zhao S, Jia L, Gao P, Li Q, Lu X, Li J, Xu G. Study on the effect of eicosapentaenoic acid on phospholipids composition in membrane microdomains of tight junctions of epithelial cells by liquid chromatography/ electrospray mass spectrometry. J Pharm Biomed Anal. 2008; 47:343-50.
48. Moreno JJ. Differential effects of arachidonic and eicosapentaenoic acid-derived eicosanoids on polymorphonuclear transmigration across endothelial cell cultures. J Pharmacol Exp Ther. 2009;331:1111-7.
49. Blikslager AT, Roberts MC, Rhoads JM, Argenzio RA. Prostaglandins I2 and E2 have a synergistic role in rescuing epithelial barrier function in porcine ileum. J Clin Invest. 1997;100:1928-33.
50. Flores-Benitez D, Rincon-Heredia R, Razgado LF, Larre I, Cereijido M, Contreras RG. Control of tight junctional sealing: roles of epidermal growth factor and prostaglandin E2. Am J Physiol Cell Physiol. 2009; 297:C611-20.
51. Auvin S, Collet F, Gottrand F, Husson MO, Leroy X, Beermann C, Guery BP. Long-chain polyunsaturated fatty acids modulate lung inflammatory response induced by Pseudomonas aeruginosa in mice. Pediatr Res. 2005;58:211-5.