Dietary effects of eicosapentaenoic and docosahexaenoic acid esters on lipid metabolism and immune parameters in sprague-dawley rats

Bioscience, Biotechnology and Biochemistry

Volumn 64, Issue 12, 2000, Pages 2588-2593

  Hung, Pham ^a   Gu, Jiong Yan ^a   Kaku, Shihoko ^a   Yunoki, Shin Ichi ^a   Ohkura, Ken Ichi ^a   Ikeda, Ikuo ^a   Tachibana, Hirofumi ^a   Sugano, Michihiro ^b   Yazawa, Kazunaga ^c   Yamada, Koji ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b PREFECTURAL UNIVERSITY OF KUMAMOTO   (Japan)

^c SAGAMI CHEMICAL RESEARCH CENTER   (Japan)

Author keywords

DHA; EPA; Fatty acid composition; LTB4; LTB5

Indexed keywords

4,7,10,13,16,19 DOCOSAHEXAENOIC ACID ETHYL ESTER; 4,7,10,13,16,19-DOCOSAHEXAENOIC ACID ETHYL ESTER; CALCIMYCIN; DOCOSAHEXAENOIC ACID; DRUG DERIVATIVE; FATTY ACID; ICOSAPENTAENOIC ACID; ICOSAPENTAENOIC ACID ETHYL ESTER; IMMUNOGLOBULIN; IONOPHORE; LEUKOTRIENE B4; LEUKOTRIENE B5; LIPID; PHOSPHOLIPID;

ANIMAL; ARTICLE; BLOOD; CHEMISTRY; CYTOLOGY; DIET SUPPLEMENTATION; DRUG EFFECT; EXUDATE; LIPID METABOLISM; LIVER; MALE; METABOLISM; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CALCIMYCIN; DIETARY SUPPLEMENTS; DOCOSAHEXAENOIC ACIDS; EICOSAPENTAENOIC ACID; EXUDATES AND TRANSUDATES; FATTY ACIDS; IMMUNOGLOBULINS; IONOPHORES; LEUKOTRIENE B4; LIPID METABOLISM; LIPIDS; LIVER; MALE; PHOSPHOLIPIDS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 0034572592     PISSN: 09168451     EISSN: 13476947     Source Type: Journal    
DOI: 10.1271/bbb.64.2588     Document Type: Article

References (26)

1. Hornstra, G., The significance of fish and fish oil enriched food for prevention and therapy of ischaemic cardiovascular disease. In The Role of Fats in Human Nutrition, 2nd ed. (Vergroesen, A. J. and CrawfordML, eds.), pp. 151-235, Academic Press, Orlando, FL (1989).
2. Haglund, O., Luostarinen, R., Wallin, R., Wibell, L., and Saldeen, T., The effect of fish oil on triglycerides, cholesterol, fibrinogen and malondialdehyde in humans supplemented with vitamin E.J. Nutr,121,165-169 (1991).
3. Choi, Y.-S., Goto, S., Ikeda, I., and Sugano, M., Effect of dietary n-3 polyunsaturated fatty acids on cholesterol synthesis and degradation in rats of differ-ent ages.Lipids,24,45-50 (1989).
4. Lee, J. H., Ikeda, I., and Sugano, M., Effects of dietary n-6/n-3 polyunsaturated fatty acid balance on tissue lipid levels, fatty acid patterns, and eicosanoid production in rats.Nutrition,8,162-166 (1992).
5. Ikeda, I., Wakamatsu, K., Inayoshi, A., Imaizumi, K., Sugano, M., and Yazawa, K., Linolenic, eicosapentaenoic and docosahexaenoic acids affect lipid metabolism differently in rats.J. Nutr.,124,1898-1906 (1994).
6. Calder, P. C. and Newsholme, E. A., Polyunsaturated fatty acids suppress human peripheral blood lymphocyte proliferation and interleukin-2 production.Clin. Sci.,82,695-700 (1992).
7. Yamada, K., Hung, P., Yoshimura, K., Taniguchi, S., Lim, B. O., and Sugano, M., Effect of unsaturated fatty acids and antioxidants on immunoglobulin production by mesenteric lymph node lymphocytes of Sprague-Dawley rats.J. Biochem.,120,138-144 (1996).
8. −in culture medium of rat mesenteric lymph node and spleen lymphocytes.J. Biochem.,121,1054-1060 (1997).
9. Hung, P., Kaku, S., Yunoki, S., Ohkura, K., Gu, J. Y., Ikeda, I., Sugano, M., Yazawa, K., and Yamada, K., Dietary effect of EPA-rich and DHA-rich fish oils on the immune function of Sprague-Dawley rats.Biosci. Biotechnol. Biochem.,63,135-140 (1999).
10. Yamada, K., Mori, M., Matsuo, N., Shoji, K., Ueyama, T., and Sugano, M., Effect of fatty acids on accumulation and secretion of histamine in RBL-2H3 cells and leukotriene release from peritoneal exudate cells isolated from Wistar rats.J. Nutr. Sci. Vitaminol.,42,301-311 (1996).
11. Anti, M., Armelao, F., Marra, G., Percesepe, A., Bartoli, G. M., Palozza, P., Parrella, P., Carretta, C., Gentiloni, N., De Vitis, I., and Gasbarrini, G., Effect of different doses of fish oil on rectal cell proliferation in patients with sporadic colonic adenomas.Gastroenterology,107,1709-1718 (1994).
12. Reddy, B. S., Dietary fat and colon cancer: Animal model studies.Lipids,27,807-812 (1992).
13. 5by rat leukocytes.Biochem. Pharmacol.,33, 3071-3076 (1984).
14. Lee, T. H., Hoover, R. L., Williams, J. D., Sperling, R. I., Ravalese, J. III., Spur, B. W., Robinson, D. R., Corey, E. J., Lewis, R. A., and Austen, K. F., Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids onin vitroneutrophil function.N. Engl. J. Med.,312,1217-1224 (1985).
15. 5by calcium ionophore-activated human eosinophilsin vitro. J. Immunol.,150,3546-3552 (1993).
16. Reeves, G. P., Nielsen, H. F., and Fahey, C. G., AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition Ad Hoc Writing Committee on the reformulation of the AIN-76 rodent diet.J. Nutr.,123,1939-1951 (1993).
17. Folch, J., Lees, M., and Sloane-Stanley, G. H., A simple method for the isolation and purification of total lipids from animal tissues.J. Biol. Chem.,226,497-509 (1957).
18. Claude, L., and Xavier, P., Thin-layer chromatography of human platelet phospholipids with fatty acid analysis.J. Chromatogr.,420,411-416 (1987).
19. Sugano, M., Ryu, K., and Ide, T., Cholesterol dynamics in rats fed cis- and trans-octadecenoate in the form of triglyceride.J. Lipid Res.,25,474-485 (1984).
20. Lim, B. O., Yamada, K., and Sugano, M., Effects of bile acids and lectins on immunoglobulin production in rat mesenteric lymph node lymphocytes.In Vitro Cell Dev. Biol.,30,407-413 (1994).
21. 4release from rat peritoneal exudate cells.In Vitro Cell. Dev. Biol.,32,340-344 (1996).
22. Powell, W. S., Precolumn extraction and reversed-phase high-pressure liquid chromatography of prostaglandins and leukotrienes.Anal. Biochem.,164,117-131 (1987).
23. Duncan, D. B., Multiple range and multiple F test.Biometrics,11,1-42 (1955).
24. Muggli, R., Dietary fish oils increase the requirement for vitamin E in human, in Health Effects of Fish and Fish oils (Chandra R.K., ed.) pp. 201-210. ARTS Biomedical Publishers and Distributors St. Johns, Newfoundland, Canada (1989).
25. Nassar, B. A., Huang, Y. S., Manku, M. S., Das, U. N., Morse, N., and Horrobin, D. F., The influence of dietary manipulation with n-3 and n-6 fatty acids on liver and plasma phospholipid fatty acids in rats.Lipids,21,652-656 (1986).
26. Metcalfe, D. D., Food allergy.Current Opinion Immunol.,3,881-886 (1991).