Synthesis and biological evaluation of Matijing-Su derivatives as potent anti-HBV agents

Bioorganic and Medicinal Chemistry

Volumn 19, Issue 18, 2011, Pages 5352-5360

  Qiu, Jingying ^a,b   Xu, Bixue ^b   Huang, Zhengming ^c   Pan, Weidong ^b   Cao, Peixue ^b   Liu, Changxiao ^d   Hao, Xiaojiang ^b   Song, Baoan ^a   Liang, Guangyi ^b,e  

^a GUIZHOU UNIVERSITY   (China)

^b INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^c BEIJING 302 HOSPITAL   (China)

^d TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH   (China)

^e GUIYANG COLLEGE OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Anti hepatitis B virus activity; MTS derivatives; Synthesis

Indexed keywords

4 (2 CHLOROACETAMIDO)BENZOIC ACID; 4 ACETAMIDO BENZOIC ACID; 4 BROMOMETHYLBENZOATE; 4 NITROPHENYLALANINE; 4 PROPIONAMIDO BENZOIC ACID; ANTIVIRUS AGENT; LAMIVUDINE; N (N 4 ACETAMIDO BENZOYLPHENYLALANYL)PHENYLALANOL; N (N 4 ACETAMIDO BENZOYLPHENYLALANYL)TYROSINE METHYL ESTER; N (N 4 ACETAMIDO BENZOYLTYROSINEYL)PHENYLALANOL; N (N 4 CHLOROACETAMIDO BENZOYLPHENYLALANYL)PHENYLALANINE METHYL ESTER; N (N 4 PROPIONAMIDO BENZOYLPHENYLALANYL) 4 NITROPHENYLALANINE METHYL ESTER; N (N 4 PROPIONAMIDO BENZOYLPHENYLALANYL)PHENYLALANINE METHYL ESTER; N (N 4 PYRIDINYL FORMYLPHENYLALANYL) 4 NITROPHENYLALANINE METHYL ESTER; N (N 4 PYRIDINYL FORMYLPHENYLALANYL)PHENYLALANINE METHYL ESTER; N (N 4 PYRIDINYL FORMYLPHENYLALANYL)PHENYLALANOL; N (N 4 PYRIDINYL FORMYLPHENYLALANYL)TYROSINE METHYL ESTER; N (N 4 PYRIDINYL FORMYLTYROSINEYL) 4 NITROPHENYLALANINE METHYL ESTER; N (N 4 PYRIDINYL FORMYLTYROSINEYL)PHENYLALANINE METHYL ESTER; N (N 4 PYRIDINYL FORMYLTYROSINEYL)PHENYLALANOL; N (N BENZOYLPHENYLALANYL) O ACETYLPHENYLALANOL; N (N BENZOYLPHENYLALANYL) O BUTYLTYROSINE METHYL ESTER; N (N BENZOYLPHENYLALANYL) O ETHYLTYROSINE METHYL ESTER; N [N (4 DIMETHYLAMINO METHYLBENZOYL)PHENYLALANYL] O ACETYLPHENYLALANOL; N [N (4 DIMETHYLAMINO METHYLBENZOYL)PHENYLALANYL]PHENYLALANOL; N [N (4 MORPHOLINOMETHYLBENZOYL)PHENYLALANYL] O ACETYLPHENYLALANOL; N [N (4 MORPHOLINOMETHYLBENZOYL)PHENYLALANYL]PHENYLALANOL; N [N (4 PYRROLIDIN 1 YLMETHYLBENZOYL)PHENYLALANYL]PHENYLALANOL; N [N 4 [2 (DIMETHYLAMINO)ETHOXY]BENZOYLPHENYLALANYL]PHENYLALANINE METHYL ESTER; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ACIDIFICATION; ANTIVIRAL ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CONTROLLED STUDY; DRUG EFFICACY; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; HYDROLYSIS; IC 50; MELTING POINT; PHARMACOPHORE; PROTON NUCLEAR MAGNETIC RESONANCE; VIRUS REPLICATION;

ANTIVIRAL AGENTS; CELL LINE; DIPEPTIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATITIS B VIRUS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; VIRUS REPLICATION;

HEPATITIS B VIRUS;

EID: 80052573742     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2011.08.001     Document Type: Article

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