Diclofenac sodium-loaded solid lipid nanoparticles prepared by emulsion/solvent evaporation method

Journal of Nanoparticle Research

Volumn 13, Issue 6, 2011, Pages 2375-2386

  Liu, Dongfei ^a   Jiang, Sunmin ^a   Shen, Hong ^a   Qin, Shan ^a   Liu, Juanjuan ^a   Zhang, Qing ^a   Li, Rui ^a   Xu, Qunwei ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

Diclofenac sodium; Drug delivery; Drug loading; Emulsion solvent evaporation; Entrapment efficiency; Nanomedicine; Solid lipid nanoparticles; Water soluble

Indexed keywords

DICLOFENAC SODIUM; DRUG LOADING; ENTRAPMENT EFFICIENCY; NANOMEDICINES; SOLID LIPID NANOPARTICLES; WATER-SOLUBLE;

DRUG DELIVERY; ETHANOL; MEDICAL NANOTECHNOLOGY; NANOPARTICLES; ORGANIC SOLVENTS; PHASE TRANSITIONS; SODIUM;

EVAPORATION;

2 PROPANOL; ALCOHOL; BUTANOL; DICLOFENAC; EMULSIFYING AGENT; GLYCEROL; GLYCEROL STEARATE; MACROGOL 400; ORGANIC SOLVENT; PHOSPHOLIPID; PROPYLENE GLYCOL; SOLID LIPID NANOPARTICLE; TERT BUTYL ALCOHOL;

ARTICLE; DISPERSION; DRUG FORMULARY; DRUG SOLUBILITY; EMULSION; EVAPORATION; PH; PRIORITY JOURNAL; VISCOSITY;

EID: 80052570582     PISSN: 13880764     EISSN: 1572896X     Source Type: Journal    
DOI: 10.1007/s11051-010-9998-y     Document Type: Article

References (36)

1. Alexy P, Lacik I, Simkova B et al (2004) Effect of melt processing on thermo-mechanical degradation of poly (vinyl alcohol) s. Polym Degrad Stab 85:823-830
2. Almeida AJ, Souto E (2007) Solid lipid nanoparticles as a drug delivery system for peptides and proteins. Adv Drug Deliv Rev 59:478-490 (Pubitemid 47260710)
3. Araujo J, Gonzalez E, Egea MA et al (2009) Nanomedicines for ocular NSAIDs: safety on drug delivery. Nanomedicine 5:394-401
4. Attama AA, Reichl S, Muller-Goymann CC (2008) Diclofenac sodium delivery to the eye: In vitro evaluation of novel solid lipid nanoparticle formulation using human cornea construct. Int J Pharm 355:307-313
5. Baydoun L, Muller-Goymann CC (2003) Influence of n-octenylsuccinate starch on in vitro permeation of sodium diclofenac across excised porcine cornea in comparison to Voltaren ophtha. Eur J Pharm Biopharm 56:73-79 (Pubitemid 36805623)
6. Bertocchi P, Antoniella E, Valvo L et al (2005) Diclofenac sodium multisource prolonged release tablets-a comparative study on the dissolution profiles. J Pharm Biomed Anal 37:679-685 (Pubitemid 40417740)
7. Budhian A, Siegel SJ, Winey KI (2007) Haloperidol-loaded PLGA nanoparticles: Systematic study of particle size and drug content. Int J Pharm 336:367-375 (Pubitemid 46670649)
8. Castro GA, Coelho AL, Oliveira CA et al (2009) Formation of ion pairing as an alternative to improve encapsulation and stability and to reduce skin irritation of retinoic acid loaded in solid lipid nanoparticles. Int J Pharm 381:77-83
9. Cui FD, Shi K, Zhang LQ et al (2006) Biodegradable nanoparticles loaded with insulin-phospholipid complex for oral delivery: preparation, in vitro characterization and in vivo evaluation. J Control Release 114:242-250 (Pubitemid 44291843)
10. Galindo-Rodriguez S, Allemann E, Fessi H et al (2004) Physicochemical parameters associated with nanoparticle formation in the salting-out, emulsification-diffusion and nanoprecipitation methods. Pharm Res 21:1428-1439 (Pubitemid 39149658)
11. Govender T, Stolnik S, Garnett MC et al (1999) PLGA nanoparticles prepared by nanoprecipitation: drug loading and release studies of a water soluble drug. J Control Release 57:171-185 (Pubitemid 29062869)
12. Haznedar S, Dortunc B (2004) Preparation and in vitro evaluation of Eudragit microspheres containing acetazolamide. Int J Pharm 269:131-140 (Pubitemid 38032830)
13. Heiati H, Phillips NC, Tawashi R (1996) Evidence for phospholipid bilayer formation in solid lipid nanoparticles formulated with phospholipid and triglyceride. Pharm Res 13:1406-1410 (Pubitemid 26344990)
14. Italia JL, Bhatt DK, Bhardwaj V et al (2007) PLGA nanoparticles for oral delivery of cyclosporine: nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral. J Control Release 119:197-206 (Pubitemid 46778760)
15. Kaur IP, Bhandari R, Bhandari S et al (2008) Potential of solid lipid nanoparticles in brain targeting. J Control Release 127:97-109
16. Kocbek P, Baumgartner S, Kristl J (2006) Preparation and evaluation of nanosuspensions for enhancing the dissolution of poorly soluble drugs. Int J Pharm 312:179-186
17. Liu J, Gong T, Wang CG et al (2007) Solid lipid nanoparticles loaded with insulin by sodium cholate-phosphatidylcholine-based mixed micelles: preparation and characterization. Int J Pharm 340:153-162 (Pubitemid 47044961)
18. Lucks JS, Muller RH (1991) Medication vehicles made of solid lipid particles (solid lipid nanospheres, SLN). EP 0605497
19. Mehnert W, Mader K (2001) Solid lipid nanoparticles production, characterization and applications. Adv Drug Deliv Rev 47:165-196 (Pubitemid 32324113)
20. Muchow M, Maincent P, Muller RH (2008) Lipid nanoparticles with a solid matrix (SLN, NLC, LDC) for oral drug delivery. Drug Dev Ind Pharm 34:1394-1405
21. Muller RH, Runge SA (1998) Solid lipid nanoparticles (SLN) for controlled drug delivery. In: Benita S (ed) Submicron emulsions in drug targeting and delivery. Harwood Academic Publishers, Amsterdam, pp 219-234
22. Muller RH, Mader K, Gohla S (2000) Solid lipid nanoparticles (SLN) for controlled drug delivery-a review of the state of the art. Eur J Pharm Biopharm 50:161-177 (Pubitemid 30326695)
23. Muller-Goymann CC (2004) Physicochemical characterization of colloidal drug delivery systems such as reverse micelles, vesicles, liquid crystals and nanoparticles for topical administration. Eur J Pharm Biopharm 58:343-356 (Pubitemid 39037240)
24. Myers D (1999) Surfaces, interfaces and colloids: principles and applications, 2nd edn. Wiley, New York, pp 253-294
25. Pardeike J, Hommoss A, Muller RH (2009) Lipid nanoparticles (SLN, NLC) in cosmetic and pharmaceutical dermal products. Int J Pharm 366:170-184
26. Patist A, Chhabra V, Pagidipati R et al (1997) Effect of chain length compatibility on micellar stability in sodium dodecyl sulfate/ alkyltrimethylammonium bromide solutions. Langmuir 13:432-434 (Pubitemid 127561537)
27. Peltonen L, Aitta J, Hyvonen S et al (2004) Improved entrapment efficiency of hydrophilic drug substance during nanoprecipitation of poly (l) lactide nanoparticles. AAPS Pharm Sci Tech 5:E16
28. Schubert MA, Harms M, Muller-Goymann CC (2006) Structural investigations on lipid nanoparticles containing high amounts of lecithin. Eur J Pharm Sci 27:226-236 (Pubitemid 41831258)
29. Shah KA, Date AA, Joshi MD et al (2007) Solid lipid nanoparticles (SLN) of tretinoin: potential in topical delivery. Int J Pharm 345:163-171 (Pubitemid 350087549)
30. Shahgaldian P, Da Silva E, Colemana AW et al (2003) Paraacyl-calix-arene based solid lipid nanoparticles (SLNs): a detailed study of preparation and stability parameters. Int J Pharm 253:23-38 (Pubitemid 36197828)
31. Song CX, Labhasetwar V, Murphy H et al (1997) Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery. J Control Release 43:197-212 (Pubitemid 26390968)
32. Song XR, Zhao Y, Wu WB et al (2008) PLGA nanoparticles simultaneously loaded with vincristine sulfate and verapamil hydrochloride: Systematic study of particle size and drug entrapment efficiency. Int J Pharm 350:320-329 (Pubitemid 351146679)
33. Talukder MMR, Hayashi Y, Takeyama T et al (2003) Activity and stability of Chromobacterium viscosum lipase in modified AOT reverse micelles. J Mol Catal B: Enzym 22:203-209 (Pubitemid 36578985)
34. Tesch S, Schubert H (2002) Influence of increasing viscosity of the aqueous phase on the short-term stability of protein stabilized emulsions. J Food Eng 52:305-312 (Pubitemid 34182050)
35. Valot P, Baba M, Nedelec JM et al (2009) Effects of process parameters on the properties of biocompatible ibuprofenloaded microcapsules. Int J Pharm 369:53-63
36. Wan F, You J, Sun Y et al (2008) Studies on PEG-modified SLNs loading vinorelbine bitartrate (I): preparation and evaluation in vitro. Int J Pharm 359:104-110