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Volumn 45, Issue 3, 2011, Pages 642-649

Expression profiling identifies klf15 as a glucocorticoid target that regulates airway hyperresponsiveness

Author keywords

Asthma; Glucocorticoid; Klf15

Indexed keywords

ACETYLCHOLINE; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; OVALBUMIN;

EID: 80052550954     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/rcmb.2010-0369OC     Document Type: Article
Times cited : (51)

References (48)
  • 1
    • 33644784718 scopus 로고    scopus 로고
    • Corticosteroids: The drugs to beat
    • DOI 10.1016/j.ejphar.2005.12.052, PII S0014299905013816, The Pharmacology of the Respiratory Tract
    • Barnes P.J. Corticosteroids: The drugs to beat. Eur J Pharmacol 2006;533:2-14. (Pubitemid 43340000)
    • (2006) European Journal of Pharmacology , vol.533 , Issue.1-3 , pp. 2-14
    • Barnes, P.J.1
  • 2
    • 0036810356 scopus 로고    scopus 로고
    • Mechanisms involved in the side effects of glucocorticoids
    • DOI 10.1016/S0163-7258(02)00297-8, PII S0163725802002978
    • Schacke H., Docke W.D., Asadullah K. Mechanisms involved in the side effects of glucocorticoids. Pharmacol Ther 2002;96:23-43. (Pubitemid 35346616)
    • (2002) Pharmacology and Therapeutics , vol.96 , Issue.1 , pp. 23-43
    • Schacke, H.1    Docke, W.-D.2    Asadullah, K.3
  • 3
    • 38049121369 scopus 로고    scopus 로고
    • Airway modeling and remodeling in the pathogenesis of asthma
    • Warner S.M., Knight D.A. Airway modeling and remodeling in the pathogenesis of asthma. Curr Opin Allergy Clin Immunol 2008;8:44-48.
    • (2008) Curr Opin Allergy Clin Immunol , vol.8 , pp. 44-48
    • Warner, S.M.1    Knight, D.A.2
  • 5
    • 36749082528 scopus 로고    scopus 로고
    • Glucocorticoid actions on airway epithelial responses in immunity: Functional outcomes and molecular targets
    • quiz 1264-1245
    • Stellato C. Glucocorticoid actions on airway epithelial responses in immunity: Functional outcomes and molecular targets. J Allergy Clin Immunol 2007;120:1247-1263; quiz 1264-1245.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 1247-1263
    • Stellato, C.1
  • 7
    • 37849000903 scopus 로고    scopus 로고
    • Airway smooth muscle growth in asthma: Proliferation, hypertrophy, and migration
    • Bentley J.K., Hershenson M.B. Airway smooth muscle growth in asthma: Proliferation, hypertrophy, and migration. Proc Am Thorac Soc 2008;5:89-96.
    • (2008) Proc Am Thorac Soc , vol.5 , pp. 89-96
    • Bentley, J.K.1    Hershenson, M.B.2
  • 8
    • 74849084373 scopus 로고    scopus 로고
    • Airway structural components drive airway smooth muscle remodeling in asthma
    • Dekkers B.G., Maarsingh H., Meurs H., Gosens R. Airway structural components drive airway smooth muscle remodeling in asthma. Proc Am Thorac Soc 2009;6:683-692.
    • (2009) Proc Am Thorac Soc , vol.6 , pp. 683-692
    • Dekkers, B.G.1    Maarsingh, H.2    Meurs, H.3    Gosens, R.4
  • 11
    • 0030961991 scopus 로고    scopus 로고
    • Protective effect of inhaled budesonide against unlimited airway narrowing to methacholine in atopic patients with asthma
    • DOI 10.1016/S0091-6749(97)70050-2
    • Booms P., Cheung D., Timmers M.C., Zwinderman A.H., Sterk P.J. Protective effect of inhaled budesonide against unlimited airway narrowing to methacholine in atopic patients with asthma. J Allergy Clin Immunol 1997;99:330-337. (Pubitemid 27123912)
    • (1997) Journal of Allergy and Clinical Immunology , vol.99 , Issue.3 , pp. 330-337
    • Booms, P.1    Cheung, D.2    Timmers, M.C.3    Zwinderman, A.H.4    Sterk, P.J.5
  • 14
    • 27644560427 scopus 로고    scopus 로고
    • Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: Effect of hydrofluoroalkane-flunisolide
    • DOI 10.1016/j.jaci.2005.07.029, PII S0091674905017185
    • Bergeron C., Hauber H.P., Gotfried M., Newman K., Dhanda R., Servi R.J., Ludwig M.S., Hamid Q. Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: Effect of hydrofluoroalkane-flunisolide. J Allergy Clin Immunol 2005;116:983-989. (Pubitemid 41571776)
    • (2005) Journal of Allergy and Clinical Immunology , vol.116 , Issue.5 , pp. 983-989
    • Bergeron, C.1    Hauber, H.P.2    Gotfried, M.3    Newman, K.4    Dhanda, R.5    Servi, R.J.6    Ludwig, M.S.7    Hamid, Q.8
  • 21
    • 0035148088 scopus 로고    scopus 로고
    • 2-agonists and corticosteroids
    • DOI 10.1096/fj.00-0103com
    • Pang L., Knox A.J. Regulation of TNF-alpha-induced eotaxin release from cultured human airway smooth muscle cells by beta2-agonists and corticosteroids. FASEB J 2001;15:261-269. (Pubitemid 32063206)
    • (2001) FASEB Journal , vol.15 , Issue.1 , pp. 261-269
    • Pang, L.1    Knox, A.J.2
  • 22
    • 67651162338 scopus 로고    scopus 로고
    • Noncontractile functions of airway smooth muscle cells in asthma
    • Tliba O., Panettieri R.A. Jr. Noncontractile functions of airway smooth muscle cells in asthma. Annu Rev Physiol 2009;71:509-535.
    • (2009) Annu Rev Physiol , vol.71 , pp. 509-535
    • Tliba, O.1    Panettieri Jr., R.A.2
  • 23
    • 0033161645 scopus 로고    scopus 로고
    • Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle
    • Fernandes D., Guida E., Koutsoubos V., Harris T., Vadiveloo P., Wilson J.W., Stewart A.G. Glucocorticoids inhibit proliferation, cyclin D1 expression, and retinoblastoma protein phosphorylation, but not activity of the extracellular-regulated kinases in human cultured airway smooth muscle. Am J Respir Cell Mol Biol 1999;21:77-88. (Pubitemid 129508630)
    • (1999) American Journal of Respiratory Cell and Molecular Biology , vol.21 , Issue.1 , pp. 77-88
    • Fernandes, D.1    Guida, E.2    Koutsoubos, V.3    Harris, T.4    Vadiveloo, P.5    Wilson, J.W.6    Stewart, A.G.7
  • 25
    • 80052524791 scopus 로고    scopus 로고
    • Klf15 regulates airway response to acetycholine without impacting inflammation in a murine asthma model
    • abstract
    • Masuno K., Jain M.K., Gerber A.N. Klf15 regulates airway response to acetycholine without impacting inflammation in a murine asthma model [abstract]. Am J Respir Crit Care Med 2010;181:A3954.
    • (2010) Am J Respir Crit Care Med , vol.181
    • Masuno, K.1    Jain, M.K.2    Gerber, A.N.3
  • 26
    • 77956696825 scopus 로고    scopus 로고
    • Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13
    • Amrani Y., Syed F., Huang C., Li K., Liu V., Jain D., Keslacy S., Sims M.W., Baidouri H., Cooper P.R., et al. Expression and activation of the oxytocin receptor in airway smooth muscle cells: Regulation by TNFalpha and IL-13. Respir Res 2010;11:104.
    • (2010) Respir Res , vol.11 , pp. 104
    • Amrani, Y.1    Syed, F.2    Huang, C.3    Li, K.4    Liu, V.5    Jain, D.6    Keslacy, S.7    Sims, M.W.8    Baidouri, H.9    Cooper, P.R.10
  • 27
    • 34247892181 scopus 로고    scopus 로고
    • 2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility
    • DOI 10.1152/physiolgenomics.00044.2006
    • McGraw D.W., Fogel K.M., Kong S., Litonjua A.A., Kranias E.G., Aronow B.J., Liggett S.B. Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility. Physiol Genomics 2006;27:171-177. (Pubitemid 46702030)
    • (2006) Physiological Genomics , vol.27 , Issue.2 , pp. 171-177
    • McGraw, D.W.1    Fogel, K.M.2    Kong, S.3    Litonjua, A.A.4    Kranias, E.G.5    Aronow, B.J.6    Liggett, S.B.7
  • 28
    • 63849273722 scopus 로고    scopus 로고
    • Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening
    • Gerber A.N., Masuno K., Diamond M.I. Discovery of selective glucocorticoid receptor modulators by multiplexed reporter screening. Proc Natl Acad Sci USA 2009;106:4929-4934.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 4929-4934
    • Gerber, A.N.1    Masuno, K.2    Diamond, M.I.3
  • 29
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using david bioinformatics resources
    • Huang da W, Sherman BT, Lempicki RA. Systematic and integrative analysis of large gene lists using david bioinformatics resources. Nat Protoc 2009;4:44-57.
    • (2009) Nat Protoc , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 32
    • 33748676135 scopus 로고    scopus 로고
    • ADAM33 is not essential for growth and development and does not modulate allergic asthma in mice
    • DOI 10.1128/MCB.00646-06
    • Chen C., Huang X., Sheppard D. Adam33 is not essential for growth and development and does not modulate allergic asthma in mice. Mol Cell Biol 2006;26:6950-6956. (Pubitemid 44387643)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.18 , pp. 6950-6956
    • Chen, C.1    Huang, X.2    Sheppard, D.3
  • 34
    • 67749099783 scopus 로고    scopus 로고
    • C terminus of HSC70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FOXO1
    • Li F., Xie P., Fan Y., Zhang H., Zheng L., Gu D., Patterson C., Li H. C terminus of HSC70-interacting protein promotes smooth muscle cell proliferation and survival through ubiquitin-mediated degradation of FOXO1. J Biol Chem 2009;284:20090-20098.
    • (2009) J Biol Chem , vol.284 , pp. 20090-20098
    • Li, F.1    Xie, P.2    Fan, Y.3    Zhang, H.4    Zheng, L.5    Gu, D.6    Patterson, C.7    Li, H.8
  • 36
    • 38349113170 scopus 로고    scopus 로고
    • Transforming growth factor-beta (TGF-1) down-regulates NOTCH3 in fibroblasts to promote smooth muscle gene expression
    • Kennard S., Liu H., Lilly B. Transforming growth factor-beta (TGF-1) down-regulates NOTCH3 in fibroblasts to promote smooth muscle gene expression. J Biol Chem 2008;283:1324-1333.
    • (2008) J Biol Chem , vol.283 , pp. 1324-1333
    • Kennard, S.1    Liu, H.2    Lilly, B.3
  • 37
    • 34648854513 scopus 로고    scopus 로고
    • NR4A nuclear orphan receptors: Protective in vascular disease?
    • DOI 10.1097/MOL.0b013e3282ef77d1, PII 0004143320071000000006
    • Pols T.W., Bonta P.I., De Vries C.J. NR4A nuclear orphan receptors: Protective in vascular disease? Curr Opin Lipidol 2007;18:515-520. (Pubitemid 47462203)
    • (2007) Current Opinion in Lipidology , vol.18 , Issue.5 , pp. 515-520
    • Pols, T.W.1    Bonta, P.I.2    De Vries, C.J.M.3
  • 38
    • 33845450617 scopus 로고    scopus 로고
    • Bone morphogenetic protein-induced Msx1 and Msx2 inhibit myocardin-dependent smooth muscle gene transcription
    • DOI 10.1128/MCB.00759-06
    • Hayashi K., Nakamura S., Nishida W., Sobue K. Bone morphogenetic protein-induced MSX1 and MSX2 inhibit myocardin-dependent smooth muscle gene transcription. Mol Cell Biol 2006;26:9456-9470. (Pubitemid 44904438)
    • (2006) Molecular and Cellular Biology , vol.26 , Issue.24 , pp. 9456-9470
    • Hayashi, K.1    Nakamura, S.2    Nishida, W.3    Sobue, K.4
  • 42
    • 2442715233 scopus 로고    scopus 로고
    • The allergic mouse model of asthma: Normal smooth muscle in an abnormal lung?
    • DOI 10.1152/japplphysiol.00924.2003
    • Wagers S., Lundblad L.K., Ekman M., Irvin C.G., Bates J.H. The allergic mouse model of asthma: Normal smooth muscle in an abnormal lung? J Appl Physiol 2004;96:2019-2027. (Pubitemid 38661478)
    • (2004) Journal of Applied Physiology , vol.96 , Issue.6 , pp. 2019-2027
    • Wagers, S.1    Lundblad, L.K.A.2    Ekman, M.3    Irvin, C.G.4    Bates, J.H.T.5
  • 46
    • 70350540243 scopus 로고    scopus 로고
    • Vitamin d inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1
    • Damera G., Fogle H.W., Lim P., Goncharova E.A., Zhao H., Banerjee A., Tliba O., Krymskaya V.P., Panettieri R.A. Jr. Vitamin d inhibits growth of human airway smooth muscle cells through growth factor-induced phosphorylation of retinoblastoma protein and checkpoint kinase 1. Br J Pharmacol 2009;158:1429-1441.
    • (2009) Br J Pharmacol , vol.158 , pp. 1429-1441
    • Damera, G.1    Fogle, H.W.2    Lim, P.3    Goncharova, E.A.4    Zhao, H.5    Banerjee, A.6    Tliba, O.7    Krymskaya, V.P.8    Panettieri Jr., R.A.9
  • 47
    • 64249119491 scopus 로고    scopus 로고
    • Mouse models of allergic asthma: Acute and chronic allergen challenge
    • Nials A.T., Uddin S. Mouse models of allergic asthma: Acute and chronic allergen challenge. Dis Model Mech 2008;1:213-220.
    • (2008) Dis Model Mech , vol.1 , pp. 213-220
    • Nials, A.T.1    Uddin, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.