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Volumn 54, Issue 6, 2011, Pages 1480-1490

Hypoxia-induced inflammatory cytokine secretion in human adipose tissue stromovascular cells

Author keywords

Adipose tissue; Hypoxia; Inflammation; JNK; Macrophage; Obesity; p38; T cell

Indexed keywords

ACETYLSALICYLIC ACID; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HISTAMINE H2 RECEPTOR ANTAGONIST; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METFORMIN; MITOGEN ACTIVATED PROTEIN KINASE P38; NONSTEROID ANTIINFLAMMATORY AGENT; PROTON PUMP INHIBITOR; STRESS ACTIVATED PROTEIN KINASE; CYTOKINE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

EID: 80052547131     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-011-2103-y     Document Type: Article
Times cited : (120)

References (50)
  • 1
    • 47849121225 scopus 로고    scopus 로고
    • Hypoxia in adipose tissue: A basis for the dysregulation of tissue function in obesity?
    • Trayhurn P, Wang B, Wood IS (2008) Hypoxia in adipose tissue: a basis for the dysregulation of tissue function in obesity? Br J Nutr 100:227-235
    • (2008) Br J Nutr , vol.100 , pp. 227-235
    • Trayhurn, P.1    Wang, B.2    Wood, I.S.3
  • 2
    • 35148854599 scopus 로고    scopus 로고
    • Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice
    • DOI 10.1152/ajpendo.00435.2007
    • Ye J, Gao Z, Yin J, He Q (2007) Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. Am J Physiol Endocrinol Metab 293:E1118-E1128 (Pubitemid 47535846)
    • (2007) American Journal of Physiology - Endocrinology and Metabolism , vol.293 , Issue.4
    • Ye, J.1    Gao, Z.2    Yin, J.3    He, Q.4
  • 3
    • 67650224475 scopus 로고    scopus 로고
    • Macrophages and adipocytes in human obesity: Adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization
    • Capel F, Klimcáková E, Viguerie N et al (2009) Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during calorie restriction and weight stabilization. Diabetes 58:1558-1567
    • (2009) Diabetes , vol.58 , pp. 1558-1567
    • Capel, F.1    Klimcáková, E.2    Viguerie, N.3
  • 5
    • 38149044024 scopus 로고    scopus 로고
    • Contribution of mesothelial cells in the expression of inflammatory-related factors in omental adipose tissue of obese subjects
    • Darimont C, Avanti O, Blancher F et al (2008) Contribution of mesothelial cells in the expression of inflammatory-related factors in omental adipose tissue of obese subjects. Int J Obes 32:112-120
    • (2008) Int J Obes , vol.32 , pp. 112-120
    • Darimont, C.1    Avanti, O.2    Blancher, F.3
  • 6
    • 44949098401 scopus 로고    scopus 로고
    • Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue
    • DOI 10.1016/j.metabol.2008.02.019, PII S0026049508000905
    • Fain JN, Buehrer B, Bahouth SW, Tichansky DS, Madan AK (2008) Comparison of messenger RNA distribution for 60 proteins in fat cells vs the nonfat cells of human omental adipose tissue. Metabolism 57:1005-1015 (Pubitemid 351814693)
    • (2008) Metabolism: Clinical and Experimental , vol.57 , Issue.7 , pp. 1005-1015
    • Fain, J.N.1    Buehrer, B.2    Bahouth, S.W.3    Tichansky, D.S.4    Madan, A.K.5
  • 7
    • 70349150518 scopus 로고    scopus 로고
    • Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissue
    • O'Rourke RW, Metcalf MD, White AE et al (2009) Depot-specific differences in inflammatory mediators and a role for NK cells and IFN-gamma in inflammation in human adipose tissue. Int J Obes Lond 33:978-990
    • (2009) Int J Obes Lond , vol.33 , pp. 978-990
    • O'Rourke, R.W.1    Metcalf, M.D.2    White, A.E.3
  • 12
    • 77954251401 scopus 로고    scopus 로고
    • Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes
    • Ost A, Svensson K, Ruishalme I et al (2010) Attenuated mTOR signaling and enhanced autophagy in adipocytes from obese patients with type 2 diabetes. Mol Med 16:235-246
    • (2010) Mol Med , vol.16 , pp. 235-246
    • Ost, A.1    Svensson, K.2    Ruishalme, I.3
  • 13
    • 77950938618 scopus 로고    scopus 로고
    • Hypoxia-induced Bcl-2 expression in endothelial cells via p38 MAPK pathway
    • Zhang CL, Song F, Zhang J, Song QH (2010) Hypoxia-induced Bcl-2 expression in endothelial cells via p38 MAPK pathway. Biochem Biophys Res Commun 394:976-980
    • (2010) Biochem Biophys Res Commun , vol.394 , pp. 976-980
    • Zhang, C.L.1    Song, F.2    Zhang, J.3    Song, Q.H.4
  • 14
    • 75149173154 scopus 로고    scopus 로고
    • The role of ATF-2 family transcription factors in adipocyte differentiation: Antiobesity effects of p38 inhibitors
    • Maekawa T, Jin W, Ishii S (2010) The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors. Mol Cell Biol 30:613-625
    • (2010) Mol Cell Biol , vol.30 , pp. 613-625
    • Maekawa, T.1    Jin, W.2    Ishii, S.3
  • 16
    • 20744441357 scopus 로고    scopus 로고
    • Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes
    • DOI 10.1128/MCB.25.13.5466-5479.2005
    • Robidoux J, Cao W, Quan H et al (2005) Selective activation of mitogen-activated protein (MAP) kinase kinase 3 and p38alpha MAP kinase is essential for cyclic AMP-dependent UCP1 expression in adipocytes. Mol Cell Biol 25:5466-5479 (Pubitemid 40853582)
    • (2005) Molecular and Cellular Biology , vol.25 , Issue.13 , pp. 5466-5479
    • Robidoux, J.1    Cao, W.2    Quan, H.3    Daniel, K.W.4    Moukdar, F.5    Bai, X.6    Floering, L.M.7    Collins, S.8
  • 17
    • 0026353971 scopus 로고
    • Gastrointestinal surgery for severe obesity: Consensus Development Conference Panel
    • NIH conference
    • NIH conference (1991) Gastrointestinal surgery for severe obesity: Consensus Development Conference Panel. Ann Intern Med 115:956-961
    • (1991) Ann Intern Med , vol.115 , pp. 956-961
  • 18
    • 33745967219 scopus 로고    scopus 로고
    • (5-Hydroxy-2-methyl-1, 4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo
    • Hsu YL, Cho CY, Kuo PL, Huang YT, Plumbagin LCC (2006) (5-Hydroxy-2-methyl-1, 4-naphthoquinone) induces apoptosis and cell cycle arrest in A549 cells through p53 accumulation via c-Jun NH2-terminal kinase-mediated phosphorylation at serine 15 in vitro and in vivo. J Pharmacol Exp Ther 318:484-494
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 484-494
    • Hsu, Y.L.1    Cho, C.Y.2    Kuo, P.L.3    Huang, Y.T.4    Plumbagin, L.C.C.5
  • 19
    • 34347261705 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway
    • DOI 10.1210/en.2006-1441
    • Li G, Barrett EJ, Barrett MO, Cao W, Liu Z (2007) Tumor necrosis factor-alpha induces insulin resistance in endothelial cells via a p38 mitogen-activated protein kinase-dependent pathway. Endocrinology 148:3356-3363 (Pubitemid 46996990)
    • (2007) Endocrinology , vol.148 , Issue.7 , pp. 3356-3363
    • Li, G.1    Barrett, E.J.2    Barrett, M.O.3    Cao, W.4    Liu, Z.5
  • 20
    • 70449113184 scopus 로고    scopus 로고
    • Human adipose tissue macrophages: M1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss
    • Aron-Wisnewsky J, Tordjman J, Poitou C et al (2009) Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss. J Clin Endocrinol Metab 94:4619-4623
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 4619-4623
    • Aron-Wisnewsky, J.1    Tordjman, J.2    Poitou, C.3
  • 22
    • 77956396699 scopus 로고    scopus 로고
    • Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: Implications for systemic inflammation and insulin resistance
    • Yang H, Youm YH, Vandanmagsar B et al (2010) Obesity increases the production of proinflammatory mediators from adipose tissue T cells and compromises TCR repertoire diversity: implications for systemic inflammation and insulin resistance. J Immunol 185:1836-1845
    • (2010) J Immunol , vol.185 , pp. 1836-1845
    • Yang, H.1    Youm, Y.H.2    Vandanmagsar, B.3
  • 23
    • 0036770237 scopus 로고    scopus 로고
    • Interrelationship between serum lipid profile, serum hormones and other components of the metabolic syndrome
    • Garaulet M, Pérez-Llamas F, Zamora S, Tebar FJ (2002) Interrelationship between serum lipid profile, serum hormones and other components of the metabolic syndrome. J Physiol Biochem 58:151-160 (Pubitemid 36192879)
    • (2002) Journal of Physiology and Biochemistry , vol.58 , Issue.3 , pp. 151-160
    • Garaulet, M.1    Perez-Llamas, F.2    Zamora, S.3    Tebar, F.J.4
  • 24
    • 0027459878 scopus 로고
    • Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance
    • Hotamisligil GS, Shargill NS, Spiegelman BM (1993) Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Science 259:87-91 (Pubitemid 23036092)
    • (1993) Science , vol.259 , Issue.5091 , pp. 87-91
    • Hotamisligil, G.S.1    Shargill, N.S.2    Spiegelman, B.M.3
  • 25
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF- [alpha] function
    • DOI 10.1038/39335
    • Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS (1997) Protection from obesity-induced insulin resistance in mice lacking TNF-[alpha] function. Nature 389:610-614 (Pubitemid 27446179)
    • (1997) Nature , vol.389 , Issue.6651 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 26
    • 70349971371 scopus 로고    scopus 로고
    • Themajor inflammatory mediator interleukin-6 and obesity
    • Eder K, Baffy N, Falus A, Fulop AK (2009) Themajor inflammatory mediator interleukin-6 and obesity. Inflamm Res 58:727-736
    • (2009) Inflamm Res , vol.58 , pp. 727-736
    • Eder, K.1    Baffy, N.2    Falus, A.3    Fulop, A.K.4
  • 31
    • 39149112487 scopus 로고    scopus 로고
    • PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes
    • Wang B, Wood IS, Trayhurn P (2008) PCR arrays identify metallothionein-3 as a highly hypoxia-inducible gene in human adipocytes. Biochem Biophys Res Commun 368:88-93
    • (2008) Biochem Biophys Res Commun , vol.368 , pp. 88-93
    • Wang, B.1    Wood, I.S.2    Trayhurn, P.3
  • 32
    • 47849102247 scopus 로고    scopus 로고
    • Hypoxia induces leptin gene expression and secretion in human preadipocytes: Differential effects of hypoxia on adipokine expression by preadipocytes
    • DOI 10.1677/JOE-08-0156
    • Wang B, Wood IS, Trayhurn P (2008) Hypoxia induces leptin gene expression and secretion in human preadipocytes: differential effects of hypoxia on adipokine expression by preadipocytes. J Endocrinol 198:127-134 (Pubitemid 352038192)
    • (2008) Journal of Endocrinology , vol.198 , Issue.1 , pp. 127-134
    • Wang, B.1    Wood, I.S.2    Trayhurn, P.3
  • 33
    • 35448934913 scopus 로고    scopus 로고
    • Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes
    • DOI 10.1007/s00424-007-0301-8
    • Wang B, Wood IS, Trayhurn P (2007) Dysregulation of the expression and secretion of inflammation-related adipokines by hypoxia in human adipocytes. Pflugers Arch 455:479-492 (Pubitemid 47624196)
    • (2007) Pflugers Archiv European Journal of Physiology , vol.455 , Issue.3 , pp. 479-492
    • Wang, B.1    Wood, I.S.2    Trayhurn, P.3
  • 34
    • 0036266125 scopus 로고    scopus 로고
    • Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity
    • Xu H, Uysal KT, Becherer JD, Arner P, Hotamisligil GS (2002) Altered tumor necrosis factor-alpha (TNF-alpha) processing in adipocytes and increased expression of transmembrane TNF-alpha in obesity. Diabetes 51:1876-1883 (Pubitemid 34564301)
    • (2002) Diabetes , vol.51 , Issue.6 , pp. 1876-1883
    • Xu, H.1    Teoman, U.K.2    David, B.J.3    Arner, P.4    Hotamisligil, G.S.5
  • 35
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • DOI 10.1038/35065000
    • Chang L, Karin M (2001) Mammalian MAP kinase signalling cascades. Nature 410:37-40 (Pubitemid 32225829)
    • (2001) Nature , vol.410 , Issue.6824 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 42
    • 0028985547 scopus 로고
    • Beta-adrenergic stimulation and abdominal subcutaneous fat blood flow in lean, obese, and reduced-obese subjects
    • Blaak EE, van Baak MA, Kemerink GJ, Pakbiers MT, Heidendal GA, Saris WH (1995) Beta-adrenergic stimulation and abdominal subcutaneous fat blood flow in lean, obese, and reduced-obese subjects. Metabolism 44:183-187
    • (1995) Metabolism , vol.44 , pp. 183-187
    • Blaak, E.E.1    Van Baak, M.A.2    Kemerink, G.J.3    Pakbiers, M.T.4    Heidendal, G.A.5    Saris, W.H.6
  • 43
    • 0031736759 scopus 로고    scopus 로고
    • Relationship between blood pressure, metabolic variables and blood flow in obese subjects with or without non-insulin-dependent diabetes mellitus
    • DOI 10.1046/j.1365-2362.1998.00360.x
    • Jansson PA, Larsson A, Lönnroth PN (1998) Relationship between blood pressure, metabolic variables and blood flow in obese subjects with or without non-insulin-dependent diabetes mellitus. Eur J Clin Invest 28:813-818 (Pubitemid 28488114)
    • (1998) European Journal of Clinical Investigation , vol.28 , Issue.10 , pp. 813-818
    • Jansson, P.-A.E.1    Larsson, A.2    Lonnroth, P.N.3
  • 44
    • 52649126788 scopus 로고    scopus 로고
    • Macrophage infiltration into adipose tissue may promote angiogenesis for adipose tissue remodeling in obesity
    • Pang C, Gao Z, Yin J, Zhang J, Jia W, Ye J (2008) Macrophage infiltration into adipose tissue may promote angiogenesis for adipose tissue remodeling in obesity. Am J Physiol Endocrinol Metab 295:E313-E322
    • (2008) Am J Physiol Endocrinol Metab , vol.295
    • Pang, C.1    Gao, Z.2    Yin, J.3    Zhang, J.4    Jia, W.5    Ye, J.6
  • 45
    • 62749167010 scopus 로고    scopus 로고
    • Reduced adipose tissue oxygenation in human obesity: Evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response
    • Pasarica M, Sereda OR, Redman LM et al (2009) Reduced adipose tissue oxygenation in human obesity: evidence for rarefaction, macrophage chemotaxis, and inflammation without an angiogenic response. Diabetes 58:718-725
    • (2009) Diabetes , vol.58 , pp. 718-725
    • Pasarica, M.1    Sereda, O.R.2    Redman, L.M.3
  • 48
    • 77949884840 scopus 로고    scopus 로고
    • Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes
    • Pérez de Heredia F,Wood IS, Trayhurn P (2010) Hypoxia stimulates lactate release and modulates monocarboxylate transporter (MCT1, MCT2, and MCT4) expression in human adipocytes. Pflugers Arch 459:509-518
    • (2010) Pflugers Arch , vol.459 , pp. 509-518
    • Pérez De Heredia, F.1    Wood, I.S.2    Trayhurn, P.3
  • 49
    • 34547583651 scopus 로고    scopus 로고
    • Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-d-glucose uptake in human adipocytes
    • DOI 10.1016/j.bbrc.2007.07.032, PII S0006291X07015045
    • Wood IS, Wang B, Lorente-Cebrián S, Trayhurn P (2007) Hypoxia increases expression of selective facilitative glucose transporters (GLUT) and 2-deoxy-D-glucose uptake in human adipocytes. Biochem Biophys Res Commun 361:468-473 (Pubitemid 47193119)
    • (2007) Biochemical and Biophysical Research Communications , vol.361 , Issue.2 , pp. 468-473
    • Wood, I.S.1    Wang, B.2    Lorente-Cebrian, S.3    Trayhurn, P.4


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