The σ Bdependent yabJ-spoVG operon is involved in the regulation of extracellular nuclease, lipase, and protease expression

Journal of Bacteriology

Volumn 193, Issue 18, 2011, Pages 4954-4962

  Schulthess, Bettina ^a   Bloes, Dominik A ^a,d   François, Patrice ^b   Girard, Myriam ^b   Schrenzel, Jacques ^b   Bischoff, Markus ^c   Berger Bächi, Brigitte ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c SAARLAND UNIVERSITY   (Germany)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HYDROLASE; NUCLEASE; PROTEINASE; SIGMA FACTOR; TRANSCRIPTOME; TRIACYLGLYCEROL LIPASE; VIRULENCE FACTOR;

ARTICLE; BACTERIAL VIRULENCE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MODIFICATION; GENE DELETION; GENE EXPRESSION REGULATION; GENE INACTIVATION; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; REGULATORY MECHANISM; REGULON; STAPHYLOCOCCUS AUREUS; SUBREGULON; TRANSCOMPLEMENTATION; TRANSCRIPTION REGULATION; YABJ SPOVG OPERON;

BACTERIAL PROTEINS; GENE DELETION; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC COMPLEMENTATION TEST; LIPASE; MICROCOCCAL NUCLEASE; OPERON; PEPTIDE HYDROLASES; SIGMA FACTOR; STAPHYLOCOCCUS AUREUS;

STAPHYLOCOCCUS AUREUS;

EID: 80052540898     PISSN: 00219193     EISSN: 10985530     Source Type: Journal    
DOI: 10.1128/JB.05362-11     Document Type: Article

References (54)

1. Adhikari, R. P., and R. P. Novick. 2008. Regulatory organization of the staphylococcal sae locus. Microbiology 154:949-959.
2. Ausubel, F. M., et al. 1987. Current protocols in molecular biology. John Wiley & Sons, Inc., New York, NY.
3. Baba, T., et al. 2002. Genome and virulence determinants of high virulence community-acquired MRSA. Lancet 359:1819-1827.
4. Becher, D., et al. 2009. A proteomic view of an important human pathogen- towards the quantification of the entire Staphylococcus aureus proteome. PLoS One 4:e8176.
5. Berends, E. T., et al. 2010. Nuclease expression by Staphylococcus aureus facilitates escape from neutrophil extracellular traps. J. Innate Immun. 2:576-586.
6. B activity in Staphylococcus aureus. Antimicrob. Agents Chemother. 45:1714-1720.
7. B regulon. J. Bacteriol. 186:4085-4099.
8. Bronner, S., H. Monteil, and G. Prevost. 2004. Regulation of virulence determinants in Staphylococcus aureus: complexity and applications. FEMS Microbiol. Rev. 28:183-200.
9. Burlak, C., et al. 2007. Global analysis of community-associated methicillinresistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection. Cell Microbiol. 9:1172-1190.
10. Cassat, J., et al. 2006. Transcriptional profiling of a Staphylococcus aureus clinical isolate and its isogenic agr and sarA mutants reveals global differences in comparison to the laboratory strain RN6390. Microbiology 152: 3075-3090.
11. Chan, P. F., and S. J. Foster. 1998. Role of SarA in virulence determinant production and environmental signal transduction in Staphylococcus aureus. J. Bacteriol. 180:6232-6241.
12. Charbonnier, Y., et al. 2005. A generic approach for the design of wholegenome oligoarrays, validated for genomotyping, deletion mapping and gene expression analysis on Staphylococcus aureus. BMC Genomics 6:95.
13. Cheung, A. L., A. S. Bayer, G. Zhang, H. Gresham, and Y. Q. Xiong. 2004. Regulation of virulence determinants in vitro and in vivo in Staphylococcus aureus. FEMS Immunol. Med. Microbiol. 40:1-9.
14. Cheung, A. L., K. J. Eberhardt, and V. A. Fischetti. 1994. A method to isolate RNA from gram-positive bacteria and mycobacteria. Anal. Biochem. 222: 511-514.
15. Churchill, G. A. 2004. Using ANOVA to analyze microarray data. Biotechniques 37:173-175, 177.
16. Clarke, S. R., and S. J. Foster. 2006. Surface adhesins of Staphylococcus aureus. Adv. Microb. Physiol. 51:187-224.
17. Diep, B. A., et al. 2006. Complete genome sequence of USA300, an epidemic clone of community-acquired methicillin-resistant Staphylococcus aureus. Lancet 367:731-739.
18. Dinges, M. M., P. M. Orwin, and P. M. Schlievert. 2000. Exotoxins of Staphylococcus aureus. Clin. Microbiol. Rev. 13:16-34.
19. Dunman, P. M., et al. 2001. Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. J. Bacteriol. 183:7341-7353.
20. Duthie, E. S., and L. L. Lorenz. 1952. Staphylococcal coagulase; mode of action and antigenicity. J. Gen. Microbiol. 6:95-107.
21. Fujimoto, S., and Y. Ike. 2001. pAM401-based shuttle vectors that enable overexpression of promoterless genes and one-step purification of tag fusion proteins directly from Enterococcus faecalis. Appl. Environ. Microbiol. 67: 1262-1267.
22. B activity depends on RsbU in Staphylococcus aureus. J. Bacteriol. 183:1843-1852.
23. Gill, S. R., et al. 2005. Insights on evolution of virulence and resistance from the complete genome analysis of an early methicillin-resistant Staphylococcus aureus strain and a biofilm-producing methicillin-resistant Staphylococcus epidermidis strain. J. Bacteriol. 187:2426-2438.
24. Goda, S. K., and N. P. Minton. 1995. A simple procedure for gel electrophoresis and northern blotting of RNA. Nucleic Acids Res. 23:3357-3358.
25. B-dependent protein expression in the human pathogen Staphylococcus aureus via biotinylation approach. J. Proteome Res. 9:1579-1590.
26. Holden, M. T., et al. 2004. Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc. Natl. Acad. Sci. U. S. A. 101:9786-9791.
27. B. FEMS Microbiol. Lett. 232:173-179.
28. B modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J. Bacteriol. 184:5457-5467.
29. Katayama, Y., H. Z. Zhang, and H. F. Chambers. 2004. PBP 2a mutations producing very-high-level resistance to beta-lactams. Antimicrob. Agents Chemother. 48:453-459.
30. Kim, H. H., B. J. Lee, and A. R. Kwon. 2010. Expression, crystallization, and preliminary X-ray crystallographic analysis of putative SpoVG from Staphylococcus aureus. Arch. Pharm. Res. 33:1285-1288.
31. B in Staphylococcus aureus reveals its function as a global regulator of virulence genes. J. Bacteriol. 180:4814-4820.
32. B in Staphylococcus aureus: regulation of the sigB operon in response to growth phase and heat shock. Arch. Microbiol. 167:151-159.
33. Kuroda, M., et al. 2001. Whole genome sequencing of methicillin-resistant Staphylococcus aureus. Lancet 357:1225-1240.
34. Matsuno, K., and A. L. Sonenshein. 1999. Role of SpoVG in asymmetric septation in Bacillus subtilis. J. Bacteriol. 181:3392-3401.
35. McCallum, N., et al. 2006. In vivo survival of teicoplanin-resistant Staphylococcus aureus and fitness cost of teicoplanin resistance. Antimicrob. Agents Chemother. 50:2352-2360.
36. B-dependent arlRS and yabJ-spoVG loci affect capsule formation in Staphylococcus aureus. Infect. Immun. 75:4562-4571.
37. B urges Staphylococcus aureus to thicken the cell wall and to resist beta-lactams. Biochem. Biophys. Res. Commun. 288:385-389.
38. B regulon in Staphylococcus aureus and its regulation. Int. J. Med. Microbiol. 296:237-258.
39. Perez, A. R., A. Abanes-De Mello, and K. Pogliano. 2006. Suppression of engulfment defects in Bacillus subtilis by elevated expression of the motility regulon. J. Bacteriol. 188:1159-1164.
40. Renzoni, A., et al. 2006. Transcriptomic and functional analysis of an autolysis-deficient, teicoplanin-resistant derivative of methicillin-resistant Staphylococcus aureus. Antimicrob. Agents Chemother. 50:3048-3061.
41. Rollof, J., J. H. Braconier, C. Soderstrom, and P. Nilsson-Ehle. 1988. Interference of Staphylococcus aureus lipase with human granulocyte function. Eur. J. Clin. Microbiol. Infect. Dis. 7:505-510.
42. Rosenbluh, A., C. D. Banner, R. Losick, and P. C. Fitz-James. 1981. Identification of a new developmental locus in Bacillus subtilis by construction of a deletion mutation in a cloned gene under sporulation control. J. Bacteriol. 148:341-351.
43. Rossi, J., M. Bischoff, A. Wada, and B. Berger-Bächi. 2003. MsrR, a putative cell envelope-associated element involved in Staphylococcus aureus sarA attenuation. Antimicrob. Agents Chemother. 47:2558-2564.
44. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual. Cold Spring Harbor Press, Cold Spring Harbor, NY.
45. Scherl, A., et al. 2006. Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers. BMC Genomics 7:296.
46. B-dependent yabJ-spoVG operon in Staphylococcus aureus: role in methicillin and glycopeptide resistance. Antimicrob. Agents Chemother. 53:1832-1839.
47. Boperon in Staphylococcus aureus. J. Bacteriol. 187:8006-8019.
48. Singh, V. K., J. L. Schmidt, R. K. Jayaswal, and B. J. Wilkinson. 2003. Impact of sigB mutation on Staphylococcus aureus oxacillin and vancomycin resistance varies with parental background and method of assessment. Int. J. Antimicrob. Agents 21:256-261.
49. Sinha, S., et al. 1999. Crystal structure of Bacillus subtilis YabJ, a purine regulatory protein and member of the highly conserved YjgF family. Proc. Natl. Acad. Sci. U. S. A. 96:13074-13079.
50. Talaat, A. M., et al. 2002. Genomic DNA standards for gene expression profiling in Mycobacterium tuberculosis. Nucleic Acids Res. 30:e104.
51. Unoson, C., and E. G. Wagner. 2007. Dealing with stable structures at ribosome binding sites: bacterial translation and ribosome standby. RNA Biol. 4:113-117.
52. Wang, L., J. D. Trawick, R. Yamamoto, and C. Zamudio. 2004. Genomewide operon prediction in Staphylococcus aureus. Nucleic Acids Res. 32: 3689-3702.
53. Wu, S., H. de Lencastre, and A. Tomasz. 1996. Sigma-B, a putative operon encoding alternate sigma factor of Staphylococcus aureus RNA polymerase: molecular cloning and DNA sequencing. J. Bacteriol. 178:6036-6042.
54. B in growth phase dependent regulation of virulence factors in Staphylococcus aureus. Proteomics 4:3034-3047.