Toll-like receptor 2 expression in refractory periapical lesions

International Endodontic Journal

Volumn 44, Issue 10, 2011, Pages 907-916

  Desai, S V ^a   Love, R M ^a   Rich, A M ^a   Seymour, G J ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Adaptive immunity; Antigen presenting cells; Innate immunity; Periapical cyst; Periapical granuloma; Toll like receptors

Indexed keywords

ANTIBODY; CD19 ANTIGEN; CD3 ANTIGEN; COLORING AGENT; DIAGNOSTIC AGENT; METHYL GREEN; PYRONINE; TLR2 PROTEIN, HUMAN; TOLL LIKE RECEPTOR 2;

ADOLESCENT; ADULT; AGED; ARTICLE; ASYMPTOMATIC DISEASE; B LYMPHOCYTE; CHRONIC DISEASE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; IMMUNOLOGY; LYMPHOCYTE; LYMPHOCYTE COUNT; MALE; MIDDLE AGED; ODONTOGENIC CYST; PATHOLOGY; PLASMA CELL; T LYMPHOCYTE; TOOTH PERIAPICAL DISEASE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIBODIES; ANTIGENS, CD19; ANTIGENS, CD3; ASYMPTOMATIC DISEASES; B-LYMPHOCYTES; CHRONIC DISEASE; COLORING AGENTS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LYMPHOCYTE COUNT; LYMPHOCYTES; MALE; METHYL GREEN; MIDDLE AGED; PERIAPICAL GRANULOMA; PLASMA CELLS; PYRONINE; RADICULAR CYST; T-LYMPHOCYTES; TOLL-LIKE RECEPTOR 2; YOUNG ADULT;

EID: 80052520695     PISSN: 01432885     EISSN: 13652591     Source Type: Journal    
DOI: 10.1111/j.1365-2591.2011.01893.x     Document Type: Article

References (48)

1. Akamine A, Anan H, Hamachi T, Maeda K (1994) A histochemical study of the behavior of macrophages during experimental apical periodontitis in rats. Journal of Endodontics 20, 474-8.
2. Akira S, Takeda K, Kaisho T (2001) Toll-like receptors: critical proteins linking innate and acquired immunity. Nature Immunology 2, 675-80.
3. Babal P, Soler P, Brozman M, Jakubovsky J, Beyly M, Basset F (1987) In situ characterization of cells in periapical granuloma by monoclonal antibodies. Oral Surgery, Oral Medicine, and Oral Pathology 64, 348-52.
4. Colic M, Gazivoda D, Vucevic D, Vasilijic S, Rudolf R, Lukic A (2009) Proinflammatory and immunoregulatory mechanisms in periapical lesions. Molecular Immunology 47, 101-13.
5. Cymerman JJ, Cymerman DH, Walters J, Nevins AJ (1984) Human T lymphocyte subpopulations in chronic periapical lesions. Journal of Endodontics 10, 9-11.
6. Hancock HH, Sigurdsson A, Trope M, Moiseiwitsch J (2001) Bacteria isolated after unsuccessful endodontic treatment in a North American population. Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics 91, 579-86.
7. Hayashi F, Means TK, Luster AD (2003) Toll-like receptors stimulate human neutrophil function. Blood 102, 2660-9.
8. Iwasaki A, Medzhitov R (2004) Toll-like receptor control of the adaptive immune responses. Nature Immunology 5, 987-95.
9. Janeway CA Jr (1989) Approaching the asymptote? Evolution and revolution in immunology. Cold Spring Harbor Symposia on Quantitative Biology 54, 1-13.
10. Jiang J, Zuo J, Hurst IR, Holliday LS (2003) The synergistic effect of peptidoglycan and lipopolysaccharide on osteoclast formation. Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics 96, 738-43.
11. Kakehashi S, Stanley HR, Fitzgerald RJ (1965) The effects of surgical exposures of dental pulps in germ-free and conventional laboratory rats. Oral Surgery, Oral Medicine, and Oral Pathology 20, 340-9.
12. Kawai T, Akira S (2006) TLR signaling. Cell Death & Differentiation 13, 816-25.
13. Kawashima N, Stashenko P (1999) Expression of bone-resorptive and regulatory cytokines in murine periapical inflammation. Archives of Oral Biology 44, 55-66.
14. Keller JF, Currouel F, Colomb E et al. (2010) Toll-like receptor 2 activation by lipoteichoic acid induce differential production of proinflammatory cytokine in human odontoblasts, dental pulp fibroblasts and immature dendritic cells. Immunobiology 215, 53-9.
15. Komai-Koma M, Jones L, Ogg GS, Xu D, Liew FY (2004) TLR2 is expressed on activated T cells as a costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America 101, 3029-34.
16. Lang T, Mansell A (2007) The negative regulation of Toll-like receptor and associated pathways. Immunology & Cell Biology 85, 425-34.
17. Liapatas S, Nakou M, Rontogianni D (2003) Inflammatory infiltrate of chronic periradicular lesions: an immunohistochemical study. International Endodontic Journal 36, 464-71.
18. Lin SK, Kok SH, Lin LD et al. (2007) Nitric oxide promotes the progression of periapical lesion via inducing macrophage and osteoblast apoptosis. Oral Microbiology & Immunology 22, 24-9.
19. Lin LM, Ricucci D, Lin J, Rosenburg PA (2009) Nonsurgical root canal therapy of large cyst-like inflammatory periapical lesions and inflammatory apical cysts. Journal of Endodontics 35, 607-15.
20. Liu H, Komai-Koma M, Xu D, Liew FY (2006) Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proceedings of the National Academy of Sciences of the United States of America 103, 7048-53.
21. Lukic A, Arsenijevic N, Vujanic G, Ramic Z (1990) Quantitative analysis of the immunocompetent cells in periapical granuloma: correlation with the histological characteristics of the lesions. Journal of Endodontics 16, 119-22.
22. Marcato LG, Ferlini AP, Freire Bonfim RC et al. (2008) The role of Toll-like receptors 2 and 4 on reactive oxygen species and nitric oxide production by macrophage cells stimulated with root canal pathogens. Oral Microbiology & Immunology 23, 353-9.
23. McCurdy JD, Olynych TJ, Maher LH, Marshall JS (2003) Cutting edge: distinct Toll-like receptor 2 activators selectively induce different classes of mediator production from human mast cells. Journal of Immunology 170, 1625-9.
24. Molander A, Reit C, Dahlen G, Kvist T (1998) Microbiological status of root-filled teeth with apical periodontitis. International Endodontic Journal 31, 1-7.
25. Mori Y, Yoshimura A, Ukai T, Lien E, Espevik T, Hara Y (2003) Immunohistochemical localization of Toll-like receptors 2 and 4 in gingival tissue from patients with periodontitis. Oral Microbiology & Immunology 18, 54-8.
26. Nair PN, Pajarola G, Schroeder HE (1996) Types and incidence of human periapical lesions obtained with extracted teeth. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics 81, 93-102.
27. Nilsen R, Johannessen AC, Skaug N, Matre R (1984) In situ characterization of mononuclear cells in human dental periapical inflammatory lesions using monoclonal antibodies. Oral Surgery, Oral Medicine, and Oral Pathology 58, 160-5.
28. Nilsen N, Nonstad U, Khan N et al. (2004) Lipopolysaccharide and double-stranded RNA up-regulate toll-like receptor 2 independently of myeloid differentiation factor 88. The Journal of Biological Chemistry 279, 39727-35.
29. Page G, Sattler A, Kersten S, Thiel A, Radbruch A, Miossec P (2004) Plasma cell-like morphology of Th1-cytokine-producing cells associated with the loss of CD3 expression. American Journal of Pathology 164, 409-17.
30. Pasare C, Medzhitov R (2005) Control of B-cell responses by Toll-like receptors. Nature 438, 364-8.
31. Pinheiro ET, Gomes BPFA, Ferraz CCR, Sousa ELR, Teixeira FB, Souza-Filho FJ (2003) Microorganisms from canals of root-filled teeth with periapical lesions. International Endodontic Journal 36, 1-11.
32. Shear M, Speight P (2007) Cysts of the oral and maxillofacial regions, 4th edn. Oxford: Blackwell Munksgaard, pp. 1-2.
33. Siqueira JF Jr, Rocas IN (2004) Polymerase chain reaction-based analysis of microorganisms associated with failed endodontic treatment. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology & Endodontics 97, 85-94.
34. Sjögren U, Hagglund B, Sundqvist G, Wing K (1990) Factors affecting the long-term results of endodontic treatment. Journal of Endodontics 16, 498-504.
35. Staquet MJ, Durand SH, Colomb E et al. (2008) Different roles of odontoblasts and fibroblasts in immunity. Journal of Dental Research 87, 256-61.
36. Stashenko P, Teles R, D'Souza R (1998) Periapical inflammatory responses and their modulation. Critical Reviews in Oral Biology & Medicine 9, 498-521.
37. Stern MH, Dreizen S, Mackler BF, Levy BM (1982) Isolation and characterization of inflammatory cells from the human periapical granuloma. Journal of Dental Research 61, 1408-12.
38. Sundqvist G, Figdor D, Persson S, Sjögren U (1998) Microbiologic analysis of teeth with failed endodontic treatment and the outcome of conservative re-treatment. Oral Surgery Oral Medicine Oral Pathology Oral Radiology & Endodontics 85, 86-93.
39. Suzuki T, Kumamoto H, Ooya K, Motegi K (2001) Immunohistochemical analysis of CD1a-labeled Langerhans cells in human dental periapical inflammatory lesions - correlation with inflammatory cells and epithelial cells. Oral Diseases 7, 336-43.
40. Takahashi K, MacDonald DG, Kinane DF (1996) Analysis of immunoglobulin-synthesizing cells in human dental periapical lesions by in situ hybridization and immunohistochemistry. Journal of Oral Pathology & Medicine 25, 331-5.
41. Takeuchi O, Hoshino K, Kawai T et al. (1999) Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 11, 443-51.
42. Tangye SG, Avery DT, Deenick EK, Hodgkin PD (2003) Intrinsic differences in the proliferation of naive and memory human B cells as a mechanism for enhanced secondary immune responses. Journal of Immunology 170, 686-94.
43. Torabinejad M, Kettering J, Bakland LK (1981) Localization of IgE immunoglobulin in human dental periapical lesions by the peroxidase-antiperoxidase method. Archives of Oral Biology 26, 677-81.
44. Torabinejad M, Kettering JD (1985) Identification and relative concentration of B and T lymphocytes in human chronic periapical lesions. Journal of Endodontics 11, 122-5.
45. Underhill DM, Ozinsky A, Hajjar AM et al. (1999) The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens. Nature 401, 811-5.
46. Vasilevsky S, Chattopadhyay G, Colino J et al. (2008) B and CD4+ T-cell expression of TLR2 is critical for optimal induction of a T-cell-dependent humoral immune response to intact Streptococcus pneumoniae. European Journal of Immunology 38, 3316-26.
47. Walker KF, Lappin DF, Takahashi K, Hope J, Macdonald DG, Kinane DF (2000) Cytokine expression in periapical granulation tissue as assessed by immunohistochemistry. European Journal of Oral Sciences 108, 195-201.
48. Yu SM, Stashenko P (1987) Identification of inflammatory cells in developing rat periapical lesions. Journal of Endodontics 13, 535-40.