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Volumn 876, Issue 2, 2008, Pages 182-190
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Evaluation of preparative high performance liquid chromatography and cryoprobe-nuclear magnetic resonance spectroscopy for the early quantitative estimation of drug metabolites in human plasma
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Author keywords
Human plasma; Metabolites; NMR; Preparative HPLC; Quantification
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Indexed keywords
ANIMAL CELL CULTURE;
ATOMS;
BIOCHEMISTRY;
BIOMOLECULES;
BODY FLUIDS;
CHROMATOGRAPHIC ANALYSIS;
CHROMATOGRAPHY;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HIGH PRESSURE LIQUID CHROMATOGRAPHY;
MAGNETIC RESONANCE;
MAGNETIC RESONANCE SPECTROMETERS;
MAGNETIC RESONANCE SPECTROSCOPY;
METABOLITES;
NUCLEAR MAGNETIC RESONANCE;
NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;
PARTICLE DETECTORS;
PLASMA (HUMAN);
PLASMAS;
RESONANCE;
CLINICAL DEVELOPMENTS;
CLINICAL STUDIES;
DEVELOPMENT PROCESSES;
DRUG CANDIDATES;
DRUG METABOLITES;
HUMAN PLASMA;
HUMAN PLASMAS;
IN PHASE;
NMR;
PHASE I;
PREPARATIVE HPLC;
PROOF OF CONCEPTS;
QUANTIFICATION;
QUANTITATIVE ESTIMATIONS;
LIQUID CHROMATOGRAPHY;
DRUG METABOLITE;
ARTICLE;
CALIBRATION;
CARBON NUCLEAR MAGNETIC RESONANCE;
CONTROLLED STUDY;
DRUG EFFICACY;
DRUG EXPOSURE;
DRUG SAFETY;
DRUG TOLERABILITY;
EVALUATION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
NITROGEN NUCLEAR MAGNETIC RESONANCE;
NORMAL HUMAN;
PRIORITY JOURNAL;
PROTON NUCLEAR MAGNETIC RESONANCE;
QUANTITATIVE ANALYSIS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CLINICAL TRIALS, PHASE I AS TOPIC;
DRUG MONITORING;
HUMANS;
MAGNETIC RESONANCE SPECTROSCOPY;
PHARMACEUTICAL PREPARATIONS;
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EID: 56549113149
PISSN: 15700232
EISSN: None
Source Type: Journal
DOI: 10.1016/j.jchromb.2008.10.040 Document Type: Article |
Times cited : (50)
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References (24)
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